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Transcranial magnetic stimulation-induced finger force changes under various finger coordination patterns and target finger force phases

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Neural Regeneration Research 2010年第1期5卷 64-69页

作者： Xiaoying wu Wensheng Hou Xiaolin Zheng Shan Shen Yingtao Jiang Jun Zheng Yan He Key Laboratory of Biorheological Science and Technology Ministry of Education Bioengineering College Chongqing University Chongqing 400044 China Psychology Department University of Surrey Guildford Surrey Gu2 7XFI UK Department of Computer Science New Mexico Institute of Mining and Technology Socorro NM 87801 USA Department of Electrical and Computer Engineering University of Nevada Las Vegas NV 89154 USA

BACKGROUND： The detection of motor evoked potential is utilized to explore neuromuscular finger coordination. The influence of transcranial magnetic stimulation on finger force has been investigated mainly on a single finger, and only time-dependent increased target finger force has been detected in the finger force task. OBJECTIVE： To explore the neural mechanism of finger force coordination in the motor cortex by observing the influence of various finger coordination patterns and patterns of transcranial magnetic stimulation （TMS）-induced finger force changes. DESIGN, TIME AND SETTING： Neurophysiological and behavioral study was performed at the Biomedical Engineering Laboratory of Chongqing University from April to June 2008. PARTICIPANTS： A total of 10 healthy, university students, comprising 5 males and 5 females, aged 21-23 years, voluntarily participated in this study. All participants were right-handed, with normal or corrected vision. Individuals with upper limb complaints or other musculoskeletal disorders were excluded. METHODS： A target force-tracking task was conducted on the index finger, the index and middle fingers, and four fingers （index, middle, ring, and little）, respectively. Target force trace in a single trial consisted of a 6-second ramp phase, a 20-second constant phase, and a 6-second drop phase. During experimentation, an unpredictable single-pulse TMS （120% motor threshold） was applied to the primary motor cortex （M1） in each phase. MAIN OUTCOME MEASURES： Changes in peak force induced by TMS were obtained for each finger pattern during each force-tracking phase. Differences in force changes were tested between different finger pattems with regard to ramp, constant, and drop phases of target force. RESULTS： Under ramp, constant, and drop phases of target force, the increase in magnetic stimulation-induced finger forces changes positively correlated with the number of fingers involved in the force tracking task. The magnetic stimulation-ind

关键词： transcranial magnetic stimulation finger force peak force changes finger combination

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Discrimination of brownheart of Korla pear using vibration frequency spectrum technique

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International Journal of Agricultural and Biological Engineering 2017年第2期10卷 259-266页

作者： Xu Hubo wu Jie Wang Zhaopeng Gao Yongmao Wang Zhipeng Zhao Zhengqiang College of Mechanical and Electrical Engineering Shihezi UniversityShihezi 832003XinjiangChina

The purpose of this work was to use a nondestructive method for detecting the brownheart of Korla pear to reduce the chance of infection among pears without brownheart.A mechanical impulse method based on vibration testing system was used to excite the *** consistent acquisition signal indicated that the test is repeatable at the same positions of fruit equator(cheek).A remarkable frequency signal was excited at 9-12 N force by a rubber tipped *** dominant frequency was identified at the maximum response magnitude to assess the internal defect,and the result was not influenced by the distances between the defect borders and the excitation *** sharp increase of defect mass could significantly affect the dominant *** between the dominant response frequency(fd)and the defect mass percentage(ω)was characterized by an equation fd=410.649e-0.0833ω+261.947 with a good correlation coefficient(R2=0.925).A defect mass of 2.281%was determined as a discrimination *** the threshold exceeded 2.281%,the defective pear could be classified with a high accuracy rate of 96.7%.This finding would provide guidance for determining the optimal detecting time to the brownheart of Korla pears,according to the specific storage conditions when the vibration frequency spectrum method is deployed.

关键词： nondestructive detection vibration frequency spectrum brownheart of Korla pear internal defect fruit quality

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Dynamic Bandwidth Allocation and Rate Coordination for DiffServ Environment

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wuhan University Journal of Natural Sciences 2006年第1期11卷 248-252页

作者： CHEN Gang wu Guo-xin ZHANG San-feng YOU Feng-qin Department of Computer Science and Engineering Southeast University Nanjing 210096 Jiangsu China Key Laboratory of Computer Network and Information Integration of MOE Southeast University Nanjing 210096Jiangsu China

This paper presents a novel model for dynamic bandwidth allocation and rate coordination based on DiffServ and a bandwidth broker（bb）. In this model, assignment of bandwidth was made according to a periodic trace of network characteristics per application. And adjustment of transfer rate was accomplished through negotiation with applications by a bandwidth agent. This model was evaluated using network simulator 2 （NS-2）, and distinct improvements were found in respects of delay and packet loss of overall network and single flow. Finally, the model was suggested to be leveraged to multimedia applications with properties of lower delay and lower packet loss.

关键词： QoS bandwidth broker(bb) dynamic bandwidth allocation rate coordination

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外源脱落酸对干旱胁迫下狗牙根幼苗光合特性的影响

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草原与草坪 2024年第1期44卷 99-105页

作者：李舒琦许喆吴邦高任健代微然云南农业大学动物科学技术学院云南昆明650201 中国科学院生态环境研究中心城市与区域生态国家重点实验室北京100085 云南省巧家县崇溪镇农业农村和集体经济发展中心云南昭通654600

【目的】研究外源脱落酸(ABA)对干旱胁迫下狗牙根(Cynodon dactylon)光合特性的影响,为缓解狗牙根干旱损伤及抗旱栽培提供参考依据。【方法】利用聚乙二醇(Polyethylene glycol-6000,PEG-6000)模拟中度和重度干旱胁迫,研究干旱胁迫和外... 详细信息

【目的】研究外源脱落酸(ABA)对干旱胁迫下狗牙根(Cynodon dactylon)光合特性的影响,为缓解狗牙根干旱损伤及抗旱栽培提供参考依据。【方法】利用聚乙二醇(Polyethylene glycol-6000,PEG-6000)模拟中度和重度干旱胁迫,研究干旱胁迫和外源ABA(200,500μmol/L)对狗牙根幼苗光合色素、净光合速率、气孔导度和叶绿素荧光参数等光合指标的影响。【结果】干旱胁迫降低了狗牙根叶绿素含量、净光合速率、最大荧光(Fm)、可变荧光(Fv)、电子传递速率(ETR),提高了光化学猝灭(qP)和非光化学猝灭(NPQ)(P<0.05)。外源ABA降低了干旱胁迫对光合的抑制作用,不过其效应与喷施浓度及干旱程度有关。中度干旱胁迫下,喷施500µmol/L ABA使叶绿素含量、PSII最大光化学量子产量(Fv/Fm)、qP显著提高(P<0.05);重度干旱胁迫下,外源500µmol/L ABA提高了狗牙根叶绿素含量、净光合速率和水分利用率,降低了胞间CO_(2)浓度(P<0.05),但对叶绿素荧光参数影响不显著。【结论】外源ABA可通过提高光合色素含量、水分利用率及光能转化效率等形式缓解干旱胁迫对狗牙根幼苗的伤害,使植株更好地适应干旱环境,其中喷施浓度为500µmol/L效果较好。

关键词：狗牙根干旱胁迫外源脱落酸光合特性

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Amorphous NiO_(n)coupled with trace PtO_(x)toward superior electrocatalytic overall water splitting in alkaline seawater media

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Nano Research 2023年第5期16卷 6517-6530页

作者： Wenli Yu Hongru Liu Ying Zhao Yunlei Fu Weiping Xiao Bin Dong Zexing wu Yongming Chai Lei Wang State Key Laboratory of Heavy Oil Processing College of ScienceChina University of Petroleum(East China)Qingdao 266580China Key Laboratory of Eco-chemical Engineering Ministry of EducationInternational Science and Technology Cooperation Base of Eco-chemical Engineering and Green ManufacturingCollege of Chemistry and Molecular EngineeringQingdao University of Science and TechnologyQingdao 266042China College of Science Nanjing Forestry UniversityNanjing 210037China

Developing corrosion resistance bifunctional electrocatalysts with high activity and stability toward both hydrogen evolution reaction(HER)and oxygen evolution reaction(OER),especially electrolysis in seawater,is of prime significance but still pressingly ***,in-situ introduced PtO_(x)on the derivative amorphous NiO_(n)is prepared via heat treatment of Ni ZIFL nanosheets on nickel foam under low temperature(PtO_(x)-NiO_(n)/NF).The synthesized PtO_(x)-NiO_(n)/NF possesses suprahydrophilic and aerophilic surface,then in favor of intimate contact between the electrode and electrolyte and release of the generated gas bubbles during the *** a result,the in-situ PtO_(x)-NiO_(n)/NF electrode presents outstanding bifunctional activity,which only requires extremely low overpotentials of 32 and 240 mV to reach a current density of 10 mA·cm^(-2)for HER and OER,respectively,which exceeds most of the electrocatalysts previously developed and even suppresses commercial Pt/C and RuO_(2)*** for two-electrode cell organized by PtO_(x)-NiO_(n)/NF,the voltages down to 1.57 and 1.58 V are necessary to drive 10 mA·cm^(-2)with remarkable durability in 1 M KOH and alkaline seawater,respectively,along with remarkable ***,a low cell voltage of 1.88 V is needed to achieve 1,000 mA·cm^(-2)toward water-splitting under industrial *** study provides a new idea for designing in-situ amorphous metal oxide bifunctional electrocatalyst with strong Pt–support interaction for overall water splitting.

关键词： hydrogen/oxygen evolution reaction alkaline seawater splitting amorphous structure ultralow Pt electrocatalyst

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区块链技术下考虑有仿冒品介入的二手卖家博弈与定价策略研究

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曲阜师范大学学报（自然科学版） 2024年第2期50卷 21-34页

作者：刘玲玉吴晨晨徐春明徐大川天津理工大学理学院运筹学与系统工程研究所天津市300384 北京工业大学理学部运筹学与信息工程研究所北京市100124

二手市场中的假冒现象屡见不鲜,区块链技术的溯源功能可解决这一问题,但是在区块链发展初期,无法完全保证链上信息的真实性并且采用区块链技术需要成本.该文构建了由销售正品的高质量卖家和销售仿冒品的低质量卖家组成的Stackelberg博弈... 详细信息

二手市场中的假冒现象屡见不鲜,区块链技术的溯源功能可解决这一问题,但是在区块链发展初期,无法完全保证链上信息的真实性并且采用区块链技术需要成本.该文构建了由销售正品的高质量卖家和销售仿冒品的低质量卖家组成的Stackelberg博弈.分析了卖家的最优策略:两个卖家都不采用区块链技术(NN模型),只有高质量卖家采用区块链技术(BN模型),两个卖家都采用区块链技术(bb模型).研究发现低质量卖家在一定条件下也会采用区块链技术,并且能够促进高质量卖家披露更多的产品信息.数值实验表明,当高质量卖家和低质量卖家都采用区块链技术时消费者剩余最大.

关键词：二手市场信息不对称区块链技术 Stackelberg博弈

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A nanosystem of copper(II)-disulfiram for cancer treatment with high efficacy and few side effects

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Frontiers of Materials Science 2021年第4期15卷 553-566页

作者： Liping ZHAO Xiaoxia WANG Mingxia JIANG Xinghan wu Mogen ZHANG Xiuwen GUAN Jinlong MA Weifen ZHANG College of Pharmacy Weifang Medical UniversityWeifang 261053China Department of Pathology Weifang Medical UniversityWeifang 261053China School of Clinical Medicine Weifang Medical UniversityWeifang 261053China Collaborative Innovation Center for Target Drug Delivery System Weifang Medical UniversityWeifang 261053China Shandong Engineering Research Center for Smart Materials and Regenerative Medicine Weifang Medical UniversityWeifang 261053China

Developing chemotherapy drugs with high efficacy and few side effects has been a bottleneck problem that requires an efficient *** active cancer treatment ingredient disulfiram(DSF),inspired by the copper(II)diethyldithiocarbamate complex(CuET),can be used in a one-pot synthesis method to construct a CuET delivery nanosystem(CuET-ZIFCu@HA).Due to the high biocompatibility,targeting of CD44 overexpressed cancer cells,and acid response of zeolitic imidazolate framework(ZIF)materials of hyaluronic acid(HA),we realized that CuET-ZIFCu@HA could become an effective and highly selective cancer *** in vivo and in vitro experiments have demonstrated that CuET-ZIFCu@HA has robust anti-tumor properties without evident side *** research provided a promising strategy for DSF nanosystems that involves simple preparation and high efficacy,both of which are key to reusing DSF in cancer treatment.

关键词： disulfiram copper(II)diethyldithiocarbamate complex zeolitic imidazolate framework targeted therapy

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基于近场动力学的含细观结构混凝土受压数值模拟

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湖北工业大学学报 2024年第1期39卷 86-91页

作者：邓维超李厚民吴克洋黄笑宇李子毅湖北工业大学土木建筑与环境学院湖北武汉430068 湖北武汉建工集团股份有限公司湖北武汉430000

为实现混凝土受压试验的数值模拟,尝试构建一种基于蒙特卡罗方法生成骨料参数,然后以此构建包含骨料、界面过渡区、水泥浆体三相细观结构的键基近场动力学(bond-base peridynamics,bb-PD)数值模拟方法。数值模拟的结果表明,键基近场动... 详细信息

为实现混凝土受压试验的数值模拟,尝试构建一种基于蒙特卡罗方法生成骨料参数,然后以此构建包含骨料、界面过渡区、水泥浆体三相细观结构的键基近场动力学(bond-base peridynamics,bb-PD)数值模拟方法。数值模拟的结果表明,键基近场动力学方法和细观模型两者相结合的数值模拟方法能够描述混凝土受压过程中具体形态和力学特征,初步证明这种结合的有效性,同时也体现了近场动力学方法在裂纹扩展、破坏等不连续力学问题方面上的有效性。

关键词：混凝土细观结构近场动力学非均质

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Short-term transcriptomic responses of Populus euphratica roots and leaves to drought stress

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Journal of Forestry Research 2021年第2期32卷 841-853页

作者： Peipei Jiao Zhihua wu Xu Wang Zhenbo Jiang Yanqin Wang Hong Liu Rui Qin Zhijun Li College of Life Sciences Tarim UniversityAlar 843300Xinjiang ProvincePeople’s Republic of China Key Laboratory of Biological Resource Protection and Utilization of Tarim Basin Xinjiang Production and Construction GroupAlar 843300Xinjiang ProvincePeople’s Republic of China Hubei Provincial Key Laboratory for Protection and Application of Special Plant Germplasm in wuling Area of China&Key Laboratory of State Ethnic Affairs Commission for Biological Technology College of Life SciencesSouth-Central University for NationalitiesWuhan 430074Hubei ProvincePeople’s Republic of China

Populus euphratica Oliv.,the Euphrates poplar,is the tallest tree species in the arid desert areas of Northwest *** of its drought-resistance genes is valuable to increase understanding of drought resistance ***-seq of leaves and roots under drought simulation by 25%polyethylene glycol-6000(PEG 6000)were performed at 0,4,and 12 *** and roots responded differently to drought via differentially upregulated and downregulated genes;more genes were downregulated than upregulated in both leaves and ***,these differentially expressed genes were enriched in different GO terms and KEGG *** example,GO term‘response to organic substance’and KEGG pathway‘nitrogen metabolism’were enriched for drought-stressed leaves,while GO term‘cell wall organization or biogenesis’and KEGG pathway‘zeatin biosynthesis’were enriched for drought-stressed *** enrichment of the GO term‘enzyme linked receptor protein signalling pathway’in both leaf and root drought responses suggests that these tissues may also have similar ***,roots under drought stress for four hs responded by activating programed cell *** KEGG pathway‘plant hormone signal transduction’was detected for 4-and 12-h droughtstressed leaves and 12-h drought-stressed roots,suggesting that plant hormone signal transduction plays an important role in both roots and *** enrichment of upregulated and downregulated genes for leaves and roots reflect differentially regulatory mechanisms of response to drought stress via different biological processes such as the regulation of photosynthesis and auxin signalling pathway in leaves,and the regulation of defence response and water homeostasis in *** candidate genes,including transcription factors,protein kinase,transporter,late embryogenesis abundant protein and mannitol dehydrogenase,were further selected to determine their response to drought using *** results show that the expression patte

关键词： Drought stress RNA-seq Populus euphratica qRT-PCR

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Osteoclast-derived apoptotic bodies couple bone resorption and formation in bone remodeling

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Bone Research 2021年第1期9卷 63-74页

作者： Qinyu Ma Mengmeng Liang Yutong wu Fei Luo Zaisong Ma Shiwu Dong Jianzhong Xu Ce Dou Department of Orthopedics Southwest HospitalThird Military Medical UniversityChongqing 400038China Department of Biomedical Materials Science Third Military Medical UniversityChongqing 400038China Department of Orthopedics General Hospital of Xinjiang Military CommandUrumqiXinjiang 830000China State Key Laboratory of Trauma Burns and Combined InjuryThird Military Medical UniversityChongqing 400038China Department of Orthopedic Surgery Johns Hopkins University School of MedicineBaltimoreMD 21205USA

Bone remodeling is precisely coordinated by bone resorption and *** osteoclasts generate large amounts of apoptotic bodies(ABs)marking the end of the bone resorption phase,whereas the functions of osteoclast-derived ABs remain largely ***,we identified the molecular profile of ABs derived from osteoclasts at distinct differentiation stages and investigated their corresponding *** were isolated from apoptotic bone marrow macrophages,preosteoclasts,and mature osteoclasts induced by *** signature analysis with liquid chromatography-tandem mass spectrometry suggested marked protein cargo differences among the different *** bioinformatic analysis showed that the proteomic signatures of the ABs were highly similar to those of their parental ***,pOC-ABs induced endothelial progenitor cell differentiation and increased CD31hiEmcnhi endothelial cell formation in a murine bone defect model via their PDGF-bb ***-ABs induced osteogenic differentiation of mesenchymal stem cells and facilitated osteogenesis via RANKL reverse *** summary,we mapped the detailed proteomic landscapes of ABs derived from osteoclasts and showed that their potential biological roles are important in coupling bone formation with resorption during bone remodeling.

关键词： signature landscape cargo

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