检索结果-南通市图书馆

Hepatectomy after primary repair of ruptured liver cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2007年第3期6卷 267-270页

作者： Li, Ai-Jun Zhou, Wei-Ping wu, meng-chao Luo, Xiang-Ji Second Mil Med Univ Dept Hepat Surg 3 Eastern Hepatobiliary Surg Hosp Shanghai 200438 Peoples R China

BACKGROUND: Spontaneous rupture of liver tumor is often considered a potentially life-threatening situation. The aim of the present study was to assess re-operation after emergency repair of ruptured liver cancer. METHODS: We reviewed retrospectively five patients who had been admitted within a one-year period and undergone a second operation after emergency repair of primary liver cancer rupture. RESULTS: Five patients (4 males and I female) underwent emergency repair of ruptured liver cancer in local hospitals; three of them received transarterial chemoembolization (TACE). The tumor was in the right hepatic lobe in 2 patients, middle lobe in 1, left median lobe (segment IV) in 1, and caudate lobe (segment 1) in 1. Operative methods included right hemihepatectomy in 2 patients, left partial lobectomy or wedge resection in 1, caudate lobe resection in 1, and middle lobctomy+cholecystectomy+abdominal implant resection in 1. Intra-abdominal chemotherapy was given to all 5 patients. Follow-up showed that one patient died from intrahepatic metastasis and hepatic failure six months after reoperation and that two patients died from extensive intra-abdominal metastases six months later. The remaining two patients have been surviving for 28 months. CONCLUSIONS: Re-operation is indicated for patients with primary liver cancer rupture whose liver function is good and whose foci are localized and operable. Apart from removing the primary foci, it is necessary to clear abdominal metastatic foci, irrigate the abdomen and administer chemotherapy to prolong the patient's life.

关键词： hepatectomy rupture carcinoma hepatocellular

Gene expression of hepatocyte growth factor and its receptor in HCC and nontumorous liver tissues

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 1999年第2期5卷 31-33页

作者： LUO Yun Quan, wu meng chao and CONG Wen Ming

AIM To study the changes of gene expression of hepatocyte growth factor (HGF) and hepatocyte growth factor receptor (HGFr) in hepatocellular carcinoma (HCC) tissue and nontumorous liver tissue and the relationship between these changes and the biological behavior of the *** Gene expression of HGF and HGFr in 26 cases of HCC tissue and their adjacent nontumorous liver tissues was determined with digoxigenin-labeled DNA *** Positive expression of HGF in HCC tissue was similar to that in the adjacent nontumorous liver tissue, but positive rate of HGF expression was lower than HGFr gene expression. However, HGFr expression was higher in the metastatic cases than in those without metastasis. It was found that HGFr was overexpressed in HCC tissue as well as in the adjacent nontumorous liver *** There seems to be a close relationship between overexpression of HGFr gene and tumor metastasis, and the HGF and HGFr system plays an important role in regulating tumor growth and metastasis.

关键词： liver neoplasm hepatocyte growth factor receptor, hepatocyte growth factor gene expression

Surgical treatment of xanthogranulomatous cholecystitis:experience in 33 cases

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2007年第5期6卷 504-508页

作者： Yang, Tian Zhang, Bai-He Zhang, Jin Zhang, Yong-Jie Jiang, Xiao-Qing wu, meng-chao Second Mil Med Univ Dept Biliary Tract Surg Eastern Hepatobiliary Surg Hosp Shanghai 200438 Peoples R China

BACKGROUND: Xanthogranulomatous cholecystitis (XGC) is a rare presentation of chronic cholecystitis, characterized by xanthogranuloma, severe fibrosis and foam cells, and can be a cause of difficulty in cholecystectomy. Patients with XGC are frequently misdiagnosed intraoperatively as having carcinoma of the gallbladder and are treated with extensive excision. This study aimed at providing proper surgical treatment for patients with XGC. METHODS: The clinical data of 33 patients with XGC definitely diagnosed by pathological examination over a period of 10 years were analyzed retrospectively (mean age of onset, 60 years; male/female ratio, 1.5: 1). RESULTS: Preoperatively, the 33 patients were examined by abdominal B-ultrasonography while 20 of them were further examined by computed tomography (CT). Intraoperatively, XGC associated with cholecystolithiasis was found in 97.0% of the patients, thickening of the gallbladder wall in 90.9%, xanthogranulomatous tissue invading into other tissues in 87.9%, XGC associated with choledocholithiasis in 15.2%, and Mirizzi syndrome in 9.1%. In addition, a gallbladder fistula was observed in 4 patients. Open cholecystectomy was performed on 15 patients, partial cholecystectomy on 7, cholecystectomy and partial liver wedge resection on 5, and gallbladder cancer radical correction on 6. The intraoperative misdiagnosis rate was 24.2%. Frozen-section examination was carried out in 9 patients. Postoperative complications were observed in 5 patients. CONCLUSIONS: XGC is difficult to diagnose either preoperatively or intraoperatively and definite diagnosis depends exclusively on pathological examination. Firm adhesions of the gallbladder to neighboring organs and tissues are common and lead to difficulty in surgical treatments. The mode of operation depends on specific conditions in varying cases, and since frozen-section examination plays an important role in determining the nature of the lesions, intraoperative frozen-section examinati

关键词： xanthogranulomatous cholecystitis surgical treatment cholecystectomy

Expression of vascular endothelial growth factor and its receptors KDR and Fit-1 in gastric cancer cells

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2002年第6期8卷 994-998页

作者： Hua Zhang Jian wu Lin meng Cheng-chao Shou,Peking University School ofOncology,Beij ing Institute for Cancer Research,Beijing 100034,China Department of Biochemistry and Molecular Biology Peking University School of Oncology Beijing Institute for Cancer Research China.

AIM: The expression of vascular endothelial growth factor (VEGF) and its receptors KDR and Flt-1 by gastric carcinoma tissues and different gastric carcinoma cell lines was detected to elucidate the molecular mechanism of this growth factor in promoting tumor ***: The expression of VEGF, Flt-1 and KDR was determined by reverse transcription-polymerase chain reaction (RT-PCR) in gastric cancer cell lines RF-1, RF-48,AGS-1, NCI-N87, NCI-SNU-1, NCI-SNU-5, NCI-SNU-16 and KATO-Ⅲ. The expression of Flt-1 and KDR in paraffinembedded specimens of gastric cancer was determined by immunohistochemistry. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used to assess the role of VEGF in tumor cell ***: All 8 gastric cancer cell lines analyzed expressed VEGF121 and VEGF16s and six of them expressed both Flt-1 and KDR, while cell line NCI-SNU-5 expressed Flt-1 only and cell line KATOⅢ expressed neither Flt-1 nor KDR. The gastric carcinoma tissues expressed Flt-1 and KDR widely,with the positive rate of expression of Flt-1 and KDR being 84.6 % and 70 % respectively. The exogenous VEGF stimulated the growth of KDR-positive cell lines NCI-N87 and AGS-1 in a dose-dependent manner but exhibited no effect on the growth of KDR-negative cell line ***: VEGF and its receptors KDR and Flt-1 were expressed widely in gastric carcinoma cells and the VEGF stimulated KDR-positive tumor cell growth directly. These results suggest that VEGF may play a role in promoting tumor growth and metastasis by participating in both paracrine and autocrine pathways.

关键词：血管内皮生长因子 VEGF受体 KDR Flt-1 胃癌细胞基因表达

Primary mixed germ cell tumor of the liver with sarcomatous components

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2010年第5期16卷 652-656页

作者： Xu, Ai-Min Gong, Shao-Juan Song, Wei-Hua Li, Xiao-Wei Pan, Chun-Hua Zhu, Jun-Jun wu, meng-chao Second Mil Med Univ Dept Intervent Radiotherapy 3 Eastern Hepatobiliary Surg Hosp Shanghai 200438 Peoples R China

Germ cell tumor(GCT)of the liver is extremely rare. Here,we describe a case of hepatic mixed GCT with significant sarcomatous components and elevated serum α-fetoprotein(AFP)in a 34-year-old ***,the tumor was composed of two GCTs components:yolk sac tumor and immature *** predominant components of immature teratoma consisted of several types of tissue that represented different germinal layers(endoderm,mesoderm and ectoderm) and showed varying degrees of differentiation with significant sarcomatous *** yolk sac component showed positivity for AFP and cytokeratin(AE1/ AE3).The immature teratoma components showed positivity for varying differentiation *** cytogenetic analysis revealed that the yolk sac tumor and immature teratoma were positive for i(12p)and 12p *** particular,the rhabdomyoblastic components also showed typical i(12p)and 12p *** suggested that sarcomatous components may be associated with dedifferentiation or malignant transformation of certain mesenchymal components within teratoma.

关键词： Germ cell tumor Teratoma Sarcoma Liver neoplasms

Smart Cellulose‑Based Janus Fabrics with Switchable Liquid Transportation for Personal Moisture and Thermal Management

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第1期17卷 333-347页

作者： Jianfeng Xi Yanling Lou Liucheng meng chao Deng Youlu Chu Zhaoyang Xu Huining Xiao Weibing wu Jiangsu Co‑Innovation Center of Efficient Processing and Utilization of Forest Resources International Innovation Center for Forest Chemicals and MaterialsJiangsu Provincial Key Lab of Sustainable Pulp and Paper Technology and Biomass MaterialsNanjing Forestry UniversityNanjing 210037People’s Republic of China College of Materials Science and Engineering Nanjing Forestry UniversityNanjing 210037People’s Republic of China Department of Chemical Engineering University of New BrunswickFrederictonNB E3B 5A3Canada Macromolecular Chemistry and Bavarian Polymer Institute University of BayreuthBayreuth 95440Germany

The Janus fabrics designed for personal moisture/thermal regulation have garnered significant attention for their potential to enhance human ***,the development of smart and dynamic fabrics capable of managing personal moisture/thermal comfort in response to changing external environments remains a ***,a smart cellulose-based Janus fabric was designed to dynamically manage personal moisture/*** cotton fabric was grafted with N-isopropylacrylamide to construct a temperature-stimulated transport ***,hydrophobic ethyl cellulose and hydrophilic cellulose nanofiber were sprayed on the bottom and top sides of the fabric to obtain wettability *** fabric exhibits anti-gravity directional liquid transportation from hydrophobic side to hydrophilic side,and can dynamically and continuously control the transportation time in a wide range of 3–66 s as the temperature increases from 10 to 40℃.This smart fabric can quickly dissipate heat at high temperatures,while at low temperatures,it can slow down the heat dissipation rate and prevent the human from becoming too *** addition,the fabric has UV shielding and photodynamic antibacterial properties through depositing graphitic carbon nitride nanosheets on the hydrophilic *** smart fabric offers an innovative approach to maximizing personal comfort in environments with significant temperature variations.

关键词： Directional water transport Cotton fabric Anti-gravity directional liquid transportation Janus wettability

Detection of blood AFPmRNA in nude mice bearing human HCC using nested RT-PCR and its significance

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 1998年第3期4卷 88-90页

作者： LIU Yang, ZHANG BaiHe, QIAN GuangXiang, CHEN Han and wu mengchao

ＤｅｔｅｃｔｉｏｎｏｆｂｌｏｏｄＡＦＰｍＲＮＡｉｎｎｕｄｅｍｉｃｅｂｅａｒｉｎｇｈｕｍａｎＨＣＣｕｓｉｎｇｎｅｓｔｅｄＲＴＰＣＲａｎｄｉｔｓｓｉｇｎｉｆｉｃａｎｃｅＬＩＵＹａｎｇ，ＺＨＡＮＧＢａｉＨｅ，ＱＩＡＮＧ... 详细信息

ＤｅｔｅｃｔｉｏｎｏｆｂｌｏｏｄＡＦＰｍＲＮＡｉｎｎｕｄｅｍｉｃｅｂｅａｒｉｎｇｈｕｍａｎＨＣＣｕｓｉｎｇｎｅｓｔｅｄＲＴＰＣＲａｎｄｉｔｓｓｉｇｎｉｆｉｃａｎｃｅＬＩＵＹａｎｇ，ＺＨＡＮＧＢａｉＨｅ，ＱＩＡＮＧｕａｎｇＸｉａｎｇ，ＣＨＥＮＨａ...

关键词： carcinoma, hepatocellular/pathology lung neoplasms/secondary kidney neoplasms/secondary alphafetoproteins/analysis RNA, messenger polymerase chain reaction

new anastomosis method for choledochojejunostomy by the way behind antrue pyloricum

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2013年第24期 4633-4637页

作者： YANG Xin-wei YANG Jue WANG Kui ZHANG Bao-hua SHEN Feng wu meng-chao Eastern Hepatobiliary Surgery Hospital Second Military MedicalUniversity Shanghai 200438 China

Background Reflux cholangitis has been the most common In this study we intended to evaluate the perioperative and choledochojejunostomy. complication after Roux-en-Y choledochojejunostomy. long-term efficacy of a new anastomosis method for Methods Clinical data of 143 eligible patients who underwent choledochojejunostomy in the Eastern Hepatobiliary Surgery Hospital affiliated to the Second Military Medical University, China between January 2007 and December 2010 were retrospectively analyzed. Among the patients, 38 consecutive cases underwent this new anastomosis method for choledochojejunostomy （improved group, IG） and 105 underwent standard Roux-en-Y choledochojejunostomy （control group, CG）. Changes in the incidence of cholangitis, the time of beginning to eat liquid meals, post-operative delayed gastric emptying and liver function between the two groups were compared. Results There was no statistical difference in the levels of alanine transaminase, alkaline phosphomonoesterase and gamma-glutamy transferase between the two groups. The time of beginning to eat liquid meals was significantly shorter in IG than CG （P 〈0.05）. The incidence of delayed gastric emptying was lower in IG than CG, with statistical tendency between the two groups （P=0.052）. Among nine patients with different degrees of acute cholangitis in the two groups, one patient （2.6%） in IG and eight （7.6%） in CG suffered from acute cholangitis within six months of follow-up after discharge, but with no statistical difference between the two groups （P 〉0.05）. Of the nine patients with acute cholangitis, none in IG and four in CG were hospitalized for further treatment （P 〉0.05）. Conclusions Patients in IG had satisfactory perioperative and long-term prognosis with shorter time of beginning to eat liquid meals and lower incidence of delayed gastric emptying. This new procedure of choledochojejunostomy by the way behind antrue pyloricum was easy and safe to perform with no mortality and low complicat

关键词： cholangitis choledochojejunostomy anastomosis, prognosis