检索结果-南通市图书馆

Collective migrations in an epithelial–cancerous cell monolayer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Collective migrations in an epithelial–cancerous cell monol...

Modern approaches for detection of volatile organic compounds in metabolic studies focusing on pathogenic bacteria:Current state of the art

中国力学大会-2021+1

作者： Jian-Qing Lv Peng-Cheng Chen Liu-Yuan guan wojciech t.gó?d??d? Xi-Qiao Feng Bo Li Institute of Biomechanics and Medical Engineering Applied Mechanics Laboratory Department of Engineering Mechanics Tsinghua University Institute of Physical Chemistry Polish Academy of Sciences

Collective cell migration is extensively observed in embryo development and cancer *** these processes,the interactions between cells with distinct identities and fates are of importance for boundary formation and host defense against *** this paper,we explore the collective dynamics of a two-dimensional cell mixing monolayer consisting of non-tumorigenic mammary epithelial cells and breast cancer *** show that the epithelial–cancerous cell mixing system displays unique sorting *** epithelial cells aggregate to form scattered clusters,which perform random motion with simultaneous translation and rotation,strikingly distinct from the classical persistent random walk of individual migratory *** motility of cancer cells is markedly promoted by the epithelial clusters,exhibiting remarkable contact enhancement of locomotion.A discrete model based on the Johnson–Kendall–Roberts contact mechanics is proposed to identify the influence of intercellular interactions,active migration forces and cell–substrate friction forces on the collective cell *** findings could advance our understanding of many biological processes,such as cancer metastasis and tissue morphogenesis.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Journal of Pharmaceutical Analysis 2024年第4期14卷 483-505页

作者： Karolina Zuchowska wojciech Filipiak department of Pharmacodynamics and Molecular Pharmacology Faculty of PharmacyCollegium Medicum in BydgoszczNicolaus Copernicus University in Torun85-089 BydgoszczPoland

Pathogenic microorganisms produce numerous metabolites,including volatile organic compounds(VOCs).Monitoring these metabolites in biological matrices(e.g.,urine,blood,or breath)can reveal the presence of specific microorganisms,enabling the early diagnosis of infections and the timely implementation of tar-geted ***,complex matrices only contain trace levels of VOCs,and their constituent com-ponents can hinder determination of these ***,modern analytical techniques enabling the non-invasive identification and precise quantification of microbial VOCs are *** this paper,we discuss bacterial VOC analysis under in vitro conditions,in animal models and disease diagnosis in humans,including techniques for offline and online analysis in clinical *** also consider the advant.ges and limitations of novel microextraction techniques used to prepare biological samples for VOC analysis,in addition to reviewing current clinical studies on bacterial volatilomes that address inter-species in-teractions,the kinetics of VOC metabolism,and species-and drug-resistance specificity.

关键词： Volatile organic compounds Pathogenic bacteria metabolites Metabolomics Microextraction techniques gas chromat.graphy-mass spectrometry In vivo breath analysis In vitro model

Advancing Wound Filling Extraction on 3d Faces:An Auto-Segmentation and Wound Face Regeneration Approach

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2024年第5期139卷 2197-2214页

作者： duong Q.Nguyen thinh d.Le Phuong d.Nguyen Nga t.K.Le H.Nguyen-Xuan department of Mathematics and Statistics Quy Nhon UniversityQuy Nhon City55100Viet Nam Applied Research Institute for Science and technology Quy Nhon UniversityQuy Nhon City55100Viet Nam CIRtECH Institute HUTECH UniversityHo Chi Minh City72308Viet Nam

Facial wound segmentation plays a crucial role in preoperative planning and optimizing patient outcomes in various medical *** this paper,we propose an efficient approach for automating 3d facial wound segmentation using a two-stream graph convolutional *** method leverages the Cir3d-FaIR dataset and addresses the challenge of data imbalance through extensive experimentation with different loss *** achieve accurate segmentation,we conducted thorough experiments and selected a high-performing model from the *** selectedmodel demonstrates exceptional segmentation performance for complex 3d facial ***,based on the segmentation model,we propose an improved approach for extracting 3d facial wound fillers and compare it to the results of the previous *** method achieved a remarkable accuracy of 0.9999993% on the test suite,surpassing the performance of the previous *** this result,we use 3d printing technology to illustrate the shape of the wound *** outcomes of this study have significant implications for physicians involved in preoperative planning and intervention *** automating facial wound segmentation and improving the accuracy ofwound-filling extraction,our approach can assist in carefully assessing and optimizing interventions,leading to enhanced patient ***,it contributes to advancing facial reconstruction techniques by utilizing machine learning and 3d bioprinting for printing skin tissue *** source code is available at https://***/SIMOgroup/WoundFilling3d.

关键词： 3d printing technology face reconstruction 3d segmentation 3d printed model

Chebyshev polynomial-based Ritz method for thermal buckling and free vibration behaviors of metal foam beams

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2024年第5期45卷 891-910页

作者： N.d.NgUYEN t.N.NgUYEN Faculty of Civil Engineering Ho Chi Minh City University of Technology and EducationHo Chi Minh City 71309Viet Nam Faculty of Engineering and technology Kien Giang UniversityChau Thanh 92000Viet Nam

this study presents the Chebyshev polynomials-based Ritz method to examine the thermal buckling and free vibration characteristics of metal foam *** analyses include three models for porosity distribution and two scenarios for thermal *** material properties are assessed under two conditions,i.e.,temperature dependence and temperature *** theoretical framework for the beams is based on the higher-order shear deformation theory,which incorporates shear deformations with higher-order *** governing equations are established from the Lagrange equations,and the beam displacement fields are approximated by the Chebyshev *** simulations are performed to evaluate the effects of thermal load,slenderness,boundary condition(BC),and porosity distribution on the buckling and vibration behaviors of metal foam *** findings highlight the significant influence of temperature-dependent(td)material properties on metal foam beams'buckling and vibration responses.

关键词： Ritz method Chebyshev function buckling vibration metal foam beam higher-order beam theory(HOBt)

维普期刊数据库

Paper Analytical device for the Colourimetric detection of Alkaline Phosphatase in Serum and Saliva

在线全文

学校读者我要写书评

暂无评论

Journal of Analysis and testing 2024年第03期8卷 385-394页

作者： d.Alageswari A.Lakshmidevi P.E.Resmi P.V.Suneesh AarathiPradeep t.g.SatheeshBabu department of Chemistry Amrita School of Physical Sciences Coimbatore Amrita Vishwa Vidyapeetham Amrita Biosensor Research Lab Amrita School of Engineering Coimbatore Amrita Vishwa Vidyapeetham Amrita Biomedical Engineering Centre Amrita School of Engineering Coimbatore Amrita Vishwa Vidyapeetham

A paper analytical device (PAd) was developed for the colourimetric estimation of alkaline phosphatase (ALP). ALP catalyzes the hydrolysis of disodium phenyl phosphate (dSPP) to phenol, which then undergoes oxidative coupling with4-aminoantipyrine (4-AAP) producing a reddish brown-coloured quinone imine. the colourimetric reaction tested in solution has been translated onto a PAd for the point of care (PoC) testing of ALP. A uniform colour was obtained in 25 min with the introduction of ALP onto the reagent drop cast paper device. the images obtained by scanning the PAd were processed using ImageJ software. the colour intensity obtained by image processing was proportional to the concentration of ALP present in the sample. ALP in serum and saliva samples were tested using the PAd in the range of 0 to 528 U/L and0 to 187 U/L, respectively. the interference studies revealed that the PAd was selective to ALP in the presence of other biomolecules. the PAd exhibited a limit of detection (LOd) of 3.3 U/L and a sensitivity of 48.36 a.u/Log(U/L) for serum ALP and LOd of 1.69 U/L and a sensitivity of 28.5 a.u/Log (U/L) for salivary ALP. the PAd showed good agreement with the clinical methods for real samples.

关键词： Alkaline phosphatase Colourimetry ImageJ Paper analytical device Point of care testing

Atomistic Invest.gation of Shock-Induced Amorphization within Micro-shear Bands in Hexagonal Close-Packed titanium

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Acta Metallurgica Sinica(English Letters) 2024年第9期37卷 1590-1600页

作者： Z.C.Meng K.g.Wang t.Ali d.Li C.g.Bai d.S.Xu S.J.Li A.H.Feng g.J.Cao J.H.Yao Q.B.Fan H.Wang R.Yang Institute of Metal Research Chinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China Interdisciplinary Centre for Additive Manufacturing(ICAM) School of Materials and ChemistryUniversity of Shanghai for Science and TechnologyShanghai 200093China School of Materials Science and Engineering Tongji UniversityShanghai 201804China Key Laboratory for Light-Weight Materials Nanjing Tech UniversityNanjing 210009China National Key Laboratory of Science and technology on Materials Under Shock and Impact School of Materials Science and EngineeringBeijing Institute of TechnologyBeijing 100081China Beijing Institute of technology Chongqing Innovation Center Chongqing 401135China

the mechanical response of a single crystal titanium sample against(0001)α surface impact was invest.gated using molecular dynamics ***,non-uniform plastic deformation was observed in the *** high strain rates,amorphization occurred near the edge of the contact region where severe shear strain induced a large number of stacking faults(SFs)and *** contrast,the central part of the contact region underwent less deformation with significantly fewer ***,instead of amorphization by consuming SFs and dislocations,there was a gradual increase in the density of dislocations and SFs during the process of *** local amorphous regions eventually grew into shear bands.

关键词： Shock compression Amorphization Shear band titanium Molecular dynamics

Microfluidic bubble-generator enables digital light processing 3d printing of porous structures

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Aggregate

Aggregate 2024年第1期5卷 280-291页

作者： Philipp Weber Ling Cai Francisco Javier Aguilar Rojas Carlos Ezio garciamendez-Mijares Maria Celeste tirelli Francesco Nalin Jakub Jaroszewicz wojciech Swi eszkowski Marco Costantini Yu Shrike Zhang division of Engineering in Medicine Department of MedicineBrigham and Women’s HospitalHarvard Medical SchoolCambridgeMassachusettsUSA Institute of Physical Chemistry—Polish Academy of Sciences KasprzakaPoland Biomaterials group Materials Design DivisionFaculty of Materials Science and EngineeringWarsaw University of TechnologyWoloskaPoland

three-dimensional(3d)printing is an emerging technique that has shown promising success in engineering human tissues in recent *** development of vatphotopolymerization printing modalities has significantly enhanced the complexity level for 3d printing of various functional structures and ***,the development of microfluidic chip systems is an emerging research sector with promising medical *** work demonstrates the coupling of a digital light processing(dLP)printing procedure with a microfluidic chip system to produce size-tunable,3d-printable porosities with narrow pore size distributions within a gelatin methacryloyl(gelMA)hydrogel *** is found that the generation of size-tunable gas bubbles trapped within an aqueous gelMA hydrogel-precursor can be controlled with high ***,the porosities are printed in two-dimensional(2d)as well as in 3d using the dLP *** addition,the cytocompatibility of the printed porous scaffolds is invest.gated using fibroblasts,where high cell viabilities as well as cell proliferation,spreading,and migration are *** is anticipated that the strat.gy is widely applicable in a range of application areas such as tissue engineering and regenerative medicine,among others.

关键词： 3d printing biofabrication bubble digital light processing microfluidics porous

Near resonance vibration isolation on a levered-dual response(LEdAR)Coulomb-damped system by differential preloads/offsets in linear springs

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2024年第6期45卷 1033-1050页

作者： t.I.tOLUWALOJU C.K.tHEIN d.HALIM department of Mechanical Materials and Manufacturing EngineeringUniversity of Nottingham Ningbo ChinaNingbo 315100Zhejiang ProvinceChina Nottingham Ningbo China Beacons of Excellence Research and Innovation Institute University of Nottingham Ningbo ChinaNingbo 315048Zhejiang ProvinceChina

the levered-dual response(LEdAR)Coulomb-damped system attains near resonant vibration isolation by differential preloads/offsets in linear *** takes the advant.ges of both the preloads/offsets in linear springs and the guiderail friction for realizing different levels of vibration *** isolation capacities are invest.gated on the strat.gies with both the horizontal and vertical guiderails,with the horizontal rail only,and without *** compressive preloads generally result in the consumption of most of the initial excitation energy so as to overcome the potential *** isolation onsets at the frequency ratio of 1∓0.095 on the left-hand side(LHS)and the right-hand side(RHS)of the lever are relative to the load plate *** observed near resonant isolation thus makes the LEdAR system a candidate for the isolation of the mechanical systems about resonance while opening a path for simultaneous harvesterisolation functions and passive functions at extreme frequencies.

关键词： lever ratio Coulomb damping preload tension/compression isolation band/depth offset potential

维普期刊数据库

Excellent photoluminescence and electrochemical properties of Sm^(3+) doped Ca_(2)MgSi_(2)O_(7) nanophosphor:display and electrochemical sensor applications

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2024年第6期42卷 1046-1055,I0002页

作者： R.B.Basavaraj K.Sureshkumar d.P.Aarti M.B.Madhusudana Reddy g.Nagaraju t.Ramakrishnappa g.R.Navyashree K.R.Venkatesha Babu K.S.Hemalatha department of Physics BMS Institute of Technology and ManagementBangalore560064India department of Chemistry BMS Institute of Technology and ManagementBangalore560064India department of Chemistry School of Applied SciencesREVA UniversityBangalore560064India Energy Materials ResearchLaboratory Department of ChemistrySiddaganga Institute of TechnologyTumakuru57203KarnatakaIndia School of Physical Sciences REVA UniversityBangalore560057Indi department of Physics Govt.Science CollegeBengaluru560001India department of Physics Maharani Science College for WomenMaharani Cluster UniversityBengaluru560001India

A series of orange-red light emitting Ca_(2)MgSi_(2)O_(7):Sm^(3+)nanopowders were fabricated via low-cost ecofriendly green combustion technique using Aloe vera gel as *** phase purity of the samples were confirmed by the powder X-ray diffraction(PXRd)*** single-phase tetragonal structure is observed from the PXRd results with no additional impurity *** band gap energy of the fabricated powders was estimated by diffuse reflectance spectra(dRS)and is found to be in the range of 4.01-5.98 eV.A high resolution scanning electron microscope(SEM)was used to study the morphological behaviour of the ***-like structures are observed from the SEM *** particle size was evaluated by transmission electron microscopy(tEM)and is found to be~50 *** interplanar distance is found to be 0.53 *** properties were systematically studied in *** phosphors are successfully excited at 403 nm NUV light,producing reddish-orange characteristic *** emission peaks are centered at 558(^(4)g_(5/2)→^(6)H_(5/2)),607(^(4)g_(5/2)→^(6)H_(7/2))and 645 nm(^(4)g_(5/2)→^(6)H_(9/2)),*** the observed peaks the red emanation(^(4)g_(5/2)→^(6)H_(7/2))is stronger than the orange emission(^(4)g_(5/2)→^(6)H_(5/2))in the current *** photoluminescent concentration quenching is noticed above 5 mol%Sm^(3+)ion doping *** dipole-dipole interaction resulting in cross relaxation is found to be the principal cause of concentration quenching *** color features such as Commission Internationale de I’Eclairage(CIE)and correlated color temperature(CCt)were studied in *** optimized chromaticity coordinates were estimated to be(0.6363,0.3632),which fall in the reddish-orange *** average CCt value obtained is 3362 *** average color purity is found to be~82%.Sm^(3+)incorporated Ca_(2)MgSi_(2)O_(7) samples are possible contender for single white light.generation commercial candidates owing to

关键词： green combustion Photoluminescence Orange-red emission Color purity Sensors Rare earths

维普期刊数据库