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Effect of gender on the reliability of COVID-19 rapid antigen test among elderly

World Journal of Clinical Cases 2022年第29期10卷 10820-10822页

作者： Wassan Nori wisam akram Department of Obstetrics and Gynecology Mustansiriyah UniversityBaghdad 10052Iraq Department of Obstetrics and Gynecology College of MedicineMustansiriyah UniversityBaghdad 10052Iraq

Defining con-founders that affect the reliability of diagnostic tests for coronavirus disease 2019 is vital to breaking the chain of *** elderly population is a higher risk group for the emerging ***,gender seems to exert a critical role in modifying the infection risk among women owing to hormonal *** menopause transition is an exceptional period for older women where the protective and immunomodulatory effects of the estrogen hormone are ***,attention should be given to postmenopausal women since they will have an increased risk compared to their pre-menopausal peers.

关键词： COVID-19 Rapid antigen test Real-time reverse transcription-polymerase chain reaction Age Gender Postmenopausal women

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Metformin effect on internal carotid artery blood flow assessed by area under the curve of carotid artery Doppler in women with polycystic ovarian syndrome

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World Journal of Clinical Cases 2023年第6期11卷 1318-1329页

作者： wisam akram Wassan Nori Muna Abdul Ghani Zghair Department of Obstetrics and Gynecology MustansiriyahAl Saydihya 10052BaghdadIraq Department of Radiology MustansiriyahAl Saydihya 10052BaghdadIraq

BACKGROUND Insulin resistance(IR)was reported in most polycystic ovarian syndrome(PCOS)***,a biguanide drug,successfully reduced *** Model Assessment for IR(HOMA-IR)and Doppler parameters assessed metformin's *** To verify whether the area under the curve of the internal carotid artery(AUC-ICA)Doppler wave can be a useful marker for assessing IR among PCOS cases who presented with menstrual irregularity and were treated with metformin over 6 *** An observational,cross-sectional study recruited 54 eligible PCOS women;the anthropometrics were as follows:age,body mass index(BMI),menstrual cycle days,biochemical serum cholesterol,low and high-density lipoprotein,sex hormone-binding globulin,fasting blood glucose,and HOMA-IR,hormonal testosterone,luteinizing hormone over follicle-stimulating hormone ratio,and ultrasonic pulsatility index(PI)and resistance index(RI),carotid artery intima-media thickness(CIMT)and(AUC-ICA)parameters were initially recorded and repeated 3 mo and 6 mo later with metformin tab 500 mg;three times/day for 6 *** addition,AUC-ICA was assessed by taking repeated systolic and diastolic wave height *** Metformin caused a progressive reduction in BMI,menstrual cycle days,biochemical hormonal,and Doppler parameters(CIMT,PI,RI,and AUC-ICA).AUC-ICA correlated strongly to all PCOS ***-ICA correlated inversely with treatment time(r=-0.98,P<0.001)and positively with HOMA-IR(r=0.98,P<0.0001).Via the best subset regression model,the AUC-ICA had the highest predictive value for *** AUC-ICA preceded PI,RI,and CIMT with a strong,meaningful correlation to all PCOS parameters,making it a reliable marker for the assessment of IR,especially during metformin *** studies are recommended to promote the application in practice.

关键词： Carotid artery intima-media thickness Insulin resistance Internal carotid artery Doppler Metformin Polycystic ovarian syndrome

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Fertility outcomes following bariatric surgery

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World Journal of Experimental Medicine 2023年第1期13卷 1-3页

作者： Wassan Nori wisam akram Eham Amer Ali Department of Obstetrics and Gynecology Mustansiriyah UniversityBaghdad 10052SaydyiaIraq Department of Obstetrics and Gynecology MustansiriyahBaghdad 10052Al YarmoukIraq Department of Chemistry and Biochemistry MustansiriyahBaghdad 10052Iraq

Obesity impacts human health in more than one *** influence of obesity on human reproduction and fertility has been extensively *** surgery(BS)has been used as an effective tool to achieve long-term weight loss in both *** improves hormonal profiling,increasing the odds of spontaneous pregnancy and success rates following assisted reproductive techniques in infertile *** obese males,BS does improve sexual function and hormonal profile;however,conflicting reports discuss reduced sperm parameters following *** the benefits of BS in the fertility field are acknowledged,many areas call for further research,like choosing the safest surgical techniques,determining the optimal timing to get pregnant,and resolving the uncertainty of sperm parameters.

关键词： Bariatric surgery Male fertility Female fertility Assisted reproduction technique Seminal fluid

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Clinical implication of platelet to lymphocyte ratio in early onset preeclampsia:A single-center experience

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World Journal of Obstetrics and Gynecology 2023年第3期12卷 17-27页

作者： wisam akram Zina Abdullah Hussein Mazin Hameed Humadi Wassan Nori Obstetrics and Gynecology Mustansiriyah UniversityBaghdad 10052Iraq Department of Inspection Ministry of HealthBaghdad 10052Iraq

BACKGROUND Preeclampsia(PE)is a pregnancy syndrome of undetermined etiology;inflammation was one of the proposed theories for its *** To examine the platelet to lymphocyte ratio(PLR),an inflammatory biomarker,as a marker to predict poor maternal-neonatal outcomes in early-onset PE(EoPE).METHODS A cross-sectional study enrolled 60 pregnant women with EoPE(at 32-30 wk of gestation)at a university *** criteria and hematological indices were collected,including platelet counts and indices(mean platelet volume and platelet distribution width),PLR,and the Doppler study,which calculated estimated fetal weight(EFW),amniotic fluid index(AFI),resistance index(RI),and pulsatility index(PI).Participants were followed until delivery,where maternal outcomes were recorded,including;delivery mode and reason for cesarean section,and neonatal outcomes,including fetal growth restriction(FGR),meconium-stained liquid,the 5-min Apgar score,and admission to the intensive care *** There was a trend of insignificant increases in cesarean ***-one-point two percent(37/60)fetuses were admitted to the neonatal care unit;70.0%of admitted fetuses were meconium-stained liquor,and 56.7%of them had *** was positively correlated with AFI and EFW as r=0.98,0.97,P<0.001;PLR showed negative correlations with PI and RI as r=-0.99,-0.98,P<*** Apgar score and the number of days admitted to the intensive care unit had a positive and negative correlation(0.69,-0.98),P<0.0001,*** operating characteristic calculated a PLR cutoff value(7.49)that distinguished FGR at 100%sensitivity and 80%*** Strong,meaningful relationships between PLR and FGR parameters and a poor neonatal outcome with a significant P value make it a recommendable biomarker for screening EoPE-related *** studies are suggested to see the impact on maternal-neonatal health.

关键词： Preeclampsia Early onset Maternal complication Adverse perinatal outcome Apgar score

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