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In vitro antioxidant and anti-cancer activities and phytochemical analysis of Commelina benghalensis L. root extracts

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Asian Pacific Journal of Tropical Biomedicine 2020年第9期10卷 417-425页

作者： Riffat Batool Ejaz Aziz Javed Iqbal Hina Salahuddin Benny kwong-Huat Tan Saira Tabassum Tariq Mahmood University Institute of Biochemistry and Biotechnology PMAS-UAAR RawalpindiPakistan Department of Botany GDC KhanpurHaripur Pakistan Department of Plant Sciences Faculty of Biological SciencesQuaid-i-Azam UniversityIslamabad-45320Pakistan Department of Zoology University of OkaraOkaraPakistan Department of Pharmacology Yong Loo Lin School of MedicineNational University of SingaporeSingapore Department of Biotechnology Faculty of Biological SciencesQuaid-i-Azam UniversityIslamabad-45320Pakistan

Objective:To explore antioxidant potential,anti-cancer activity,and phytochemicals of Commelina benghalensis ***:The roots of Commelina benghalensis were extracted in different solvents(methanol,ethanol,benzene,chloroform,n-hexane)with a range of *** activity was evaluated by reducing power assay,DPPH radical scavenging activity and phosphomolybdenum method,cytotoxicity by MTT assay,apoptotic and cell cycle analysis by flow cytometry,migratory and invasive potential by wound scratch assay and invasion assay,respectively,functional groups analysis by FT-IR spectroscopy and phytochemicals by aluminum chloride colorimetric and FolinCiocalteu ***:The extracts showed worthy antioxidant *** chloroform extract demonstrated the most significant cytotoxic effect on MDA-MB-231(breast cancer)cell line,induced apoptosis and reduced migratory and invasive potential of MDA-MB-231 *** and ethanol extracts presented good yield of total phenolic and total flavonoid *** FTIR spectroscopic studies revealed different characteristic peak values with various functional compounds such as alkenes,alkanes,aliphatic amines,aromatics,alkyl halides,carboxylic acid,alcohols,ester,aldehydes and ***:The results demonstrate the potential use of Commelina benghalensis as a good antioxidant with significant anticancer effect.

关键词： Commelina benghalensis Anti-cancer Antioxidant FT-IR

Financial reporting of cash flow： Arbitrary items and management preferences

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Journal of Modern Accounting and Auditing 2010年第4期6卷 1-14,25页

作者： Lau Chee kwong Faculty of Business and Accountancy INTI International University College Putra Nilai 71800 Malaysia

The international financial reporting standard for cash flow statement （IAS 7） provides options for the classification of certain cash flow items （arbitrary items）. Therefore, business firms may classify the arbitrary items using the option that would maximize their own interest. This reduces the comparability of financial statements amongst business firms. This study aims to investigate the factors explaining management preferences in the selection of financial reporting practices on the arbitrary cash flow items. It concludes that managers tend to magnify the CFO reported in order to maximize the shareholders＇ wealth, which in turn would maximize their compensation. Managers of business firms with a relatively smaller size of CFO tend to classify interest paid and dividends paid as non-CFO in order to magnify their CFO. They also tend to classify interest received as CFO in order to inflate their relatively smaller size of CFO up to expectation. Similarly, managers of business firms with a relative larger size of dividends paid would classify the dividends paid outside CFO.

关键词： cash flow reporting arbitrary items management preference

A comparison of the clinical, demographic and psychiatric profiles among patients with erosive and non-erosive reflux disease in a multi-ethnic Asian country

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World Journal of Gastroenterology 2005年第23期11卷 3558-3561页

作者： Tiing-Leong Ang kwong-Ming Fock Tay-Meng Ng Eng-Kiong Teo Tju-Siang Chua Jessica Tan Division of Gastroenterology

AIM:To examine the clinical spectrum of gastroesophageal reflux disease (GERD) and compare erosive (ERD) with non-erosive (NERD) in terms of clinical, demographic and psychiatric profiles. METHODS: Patients with reflux symptoms were enrolled and stratified to NERD and ERD after endoscopy (LA classification). Patients with ERD presenting with dyspepsia were included. Patients on proton pump inhibitors (PPI) or H2 receptor antagonists before endoscopy were excluded. Demographic data, Helicobacter pylori(H pylori) status and presence of minor psychiatric morbidity (based on General Health Questionnaire-28) were analyzed. RESULTS: Among 690 patients screened, 533 were eligible for analysis (male to female ratio: 3:2; Chinese: 75.4%; Malay: 9.8%; Indian: 14.8%). Clinical spectrum of GERD: N: 40.5%; A: 46%; B: 9.2%; C: 2.1%; D: 0.6%; Barrett's esophagus: 1.7%. Compared to patients with NERD, patients with ERD were significantly older (45 vs 39.4 years), more likely to be male (64.4% vs 53.7%), tended to smoke (19.6% vs 9.7%), less likely to have minor psychiatric morbidity (26.4 vs 46.7%) and were more likely to respond to PPI (79.7 vs 66.8%). There was also a trend towards a higher BMI (24.5 vs 23.5). Race, alcohol consumption and H pylori status were not significant. On multivariate analysis, age and presence of minor psychiatric morbidity remained with significant differences. CONCLUSION: The majority of patients who have typical symptoms of GERD have NERD or mild erosive reflux disease. Compared to patients with erosive reflux disease, patients with NERD were younger and had a higher prevalence of minor psychiatric morbidity.

关键词： Reflux disease Clinical spectrum Psychiatric morbidity

Silver(Ⅱ) 5,10,15,20-tetra(ethoxycarbonyl) porphyrin:An unexpected six-coordinate linear assembled structure

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Chinese Chemical Letters 2018年第9期29卷 1404-1408页

作者： Hua-Hua Wang Hai-Yang Liu Fan Cheng Atif Ali Lei Shi Xin-Yan Xiao Chi-kwong Chang School of Chemistry and Chemical Engineering Key Laboratory of Functional Molecular Engineering of Guangdong Province South China University of Technology Department of Chemistry Southern University of Science and Technology Department of Chemistry Guangdong University of Education Department of Chemistry Michigan State University

The crystal structure of silver（Ⅱ） 5,10,15,20-tetra（ethoxycarbonyl）porphyrin （Ag[Ⅱ]TECP） revealed it formed a one-dimensional coordination polymer through weak Ag-O interactions with an unusual six-coordinated... 详细信息

关键词： Porphyrin Silver Six-coordinated assembly Crystal structure Hydrogen bond

A NOVEL DEHYDROGENATION REACTION UNDER SINGLET OXYGENATION CONDITION

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Chinese Chemical Letters 1991年第8期2卷 613-616页

作者： Hiu kwong LEUNG Yong Yue LIN Zhi Ming LIN Institute of Photographic Chemistry Academia SinicaBeijing 100101

1-Aryl-2-merhy1-4,5-dihydropyrro1-3-carboxylic acid ethyl ester was observed to dehydrogenate to give 1-ary1-2-methyl-pyrro1-3-carboxylic acid ethyl ester upon irradiation in the presence of oxygen and in the presence... 详细信息

关键词： TPP A NOVEL DEHYDROGENATION REACTION UNDER SINGLET OXYGENATION CONDITION than

RECOMBINANT TISSUE-PLASMINOGEN ACTIVATOR(rt-PA)IN ACUTE MYOCARDIAL INFARCTION IN THE CHINESEIN HONG KONG

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中华医学杂志(英文版) 1992年第5期105卷 374-378页

作者： Woo Kam Sang Tse Kin Kee Mak Yiu kwong Chung Hau kwong Tse Chun Yan Department of Medicine Prince of Wales Hospital The Chinese University of Hong Kong Hong Kong Medical Unit United Christian Hospital Hong Kong

Eighty-nine consecutive Chinese patients(69males,20 females)with acute myocardial infarctiontreated by 100 mg recombinant tissue-plasminogenactivator(rt-PA)(7 intracoronarily,82 intravenously)at 3.7±1.0 hours after onset,and intravenous heparinor dipyridamole therapy started at 3 hours,were stu-died *** mean age was 59.6±***-six patients(51.7%)had anterior and 39patients(43.8%)had inferior *** evi-dence of reperfusion was seen in 63 patients(72.8%),while new complications included hypotension(5.6%),heart failure(6.7%),cardiac arrhythmias(76.4%),hematoma around vascular access sites(23.6%),melena(2.2%)and cerebral infarction(2.2%).Maximal changes in coagulation profiles were seen at3 hours,including a decrease in fibrinogen(by 64.2%),an increase in FDP by 11.7 times and D-dimers by *** patients(10.1%)had recurrence of anginaand 6 patients(6.9%)died due to pump failure(5)andreinfarction(1).Angiogram at 14 days confirmedTIMI(2 or 3)patency of infarct related arteries in62/81(76.5%)patients,with a mean global ejectionfraction of 52.5±12.4%.Nearly all survivors couldmaintain class Ⅰ-Ⅱ functional status after *** safety and promises of rt-PA for acutemyocardial infarction in the Chinese were confirmed.

关键词：

SOMECONSEOUENCESOFTHEABSOLUTECESAROSUMMABILITYOFFOURIERSERIES

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浙江大学学报(理学版) 1964年第4期 27-28页

作者： Chen Kien-kwong

关键词： SOMECONSEOUENCESOFTHEABSOLUTECESAROSUMMABILITYOFFOURIERSERIES

Epinephrine injection therapy versus a combination of epinepnrine injection and endoscopic hemoclip in the treatment of bleeding ulcers

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World Journal of Gastroenterology 2005年第7期11卷 1044-1047页

作者： Tju-Siang Chua kwong-Ming Fock Tay-Meng Ng Eng-Kiong Teo Jessica Yi-Lyn Tan Tiing-Leong Ang Division of Gastroenterology

AIM: To assess the efficacy of hemoclip application in combination with epinephrine injection in the treatment of bleeding peptic ulcers and to compare the clinical outcomes between patients treated with such a combination therapy and those treated with epinephrine injection ***: A total of 293 patients (211 males, 82females) underwent endoscopic therapy for bleeding peptic ulcers. Of these, 202 patients (152 males, 50females) received epinephrine injection therapy while 91patients (59 males, 32 females) received combination therapy. The choice of endoscopic therapy was made by the endoscopist. Hemostatic rates, rebleeding rates, need for emergency surgery and 30-d mortality were the outcome measures ***: Patients who received combination therapy were significantly older (mean age 66±16 years, range24-90 years) and more suffered from chronic renal failure compared to those who received epinephrine injection therapy alone (mean age 61±17 years, range 21-89 years).Failure to achieve permanent hemostasis was 4% in the group who received epinephrine injection alone and 11%in the group who received combination therapy. When the differences in age and renal function between the two treatment groups were taken into account by multivariate analysis, the rates of initial hemostasis,rebleeding rates, need for surgery and 30-d mortality for both treatment options were not significantly ***: Combination therapy of epinephrine injection with endoscopic hemoclip application is an effective method of achieving hemostasis in bleeding peptic ulcer diseases. However, superiority of combination therapy over epinephrine injection alone, could not be demonstrated.

关键词： Bleeding peptic ulcer Epinephrine Endoscopic hemoclip Combination therapy

Case synthesis of a β-chloro bulky bis-pocket corrole:Crystallographic characterization and photophysical properties

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Chinese Chemical Letters 2018年第12期29卷 1888-1892页

作者： Atif Ali Fan Cheng Wei-Hong Wen Xiao Ying Jaipal KANDhadi Hui Wang Hai-Yang Liu Chi-kwong Chang Department of Chemistry Key Laboratory of Functional Molecular Engineering of Guangdong Province South China University of Technology Department of Applied Physics South China University of Technology State Key Laboratory of Optoelectronics Materials and Technologies Sun Yat-sen University Department of Chemistry Michigan State University

A new 2-chloro-5,10,15-tris（2,4,6-triphenylphenyl）-corrole was accidentally synthesized in an acceptable yield of 5.7% during the synthesis of its parent corrole, in which DDQ served as oxidant and chlorinating agent. The compound was well characterized by X-ray diffraction analysis,;H NMR, mass spectroscopy and absorption spectroscopy. Photophysical properties tests revealed that the chlorination caused a sharp decrease in fluorescence intensity, fluorescence life time, and fluorescence quantum *** investigation demonstrated the positive shift of redox potentials for chlorinated corrole as compared to non-chlorinated corrole.

关键词： Corrole β-Chlorination Synthesis Photophysical properties Singlet oxygen