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Increased Drying Rate Lowers the Critical Water Content for Survival in embryonic Axes of english Oak (Quercus robur L.) Seeds

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Journal of Integrative Plant Biology 2011年第4期53卷 270-280页

作者： Tobias M.Ntuli william.e.finch-savage Patricia Berjak Norman W.Pammenter Plant Germplasm Conservation Research School of Biological and Conservation SciencesUniversity of KwaZulu-NatalWestville CampusPrivate Bag X54001Durban 4000South Africa Department of Life and Consumer Sciences University of South AfricaPrivate Bag X6Florida 1710JohannesburgSouth Africa Warwick HRI Warwick UniversityWellesbourneWarwick CV35 9EFUK Plant Germplasm Conservation Research School of Biological and Conservation SciencesUniversity of KwaZulu-NatalWestville

The potential to cryopreserve embryonic axes of desiccation-sensitive（recalcitrant） seeds is limited by damage during the desiccation necessary for low temperature survival,but the basis of this injury and how to reduce it is not well *** effects of drying rate on the viability,respiratory metabolism and free radical-mediated processes were therefore investigated during dehydration of Quercus robur L embryonic ***,assessed by evidence of germination and tetrazolium staining,showed a sharp decline at 0.27 and 0.8 g/g during rapid（〈12 h） or slow（3d） dehydration,*** dehydration therefore lowered the critical water content for *** any given water content rapid dehydration was associated with higher activities of the free radical processing enzymes,superoxide dismutase,catalase and glutathione reductase and lower levels of hydroperoxide and membrane *** dehydration was also associated with lower malate dehydrogenase activity,and a reduced decline in phosphofructokinase activity and in levels of the oxidized form of nicotinamide *** may have contributed to increased damage during slow dehydration,since viability declined even in hydrated storage after 3 *** results presented are consistent with rapid dehydration reducing the accumulation of damage resulting from desiccation induced aqueous-based deleterious reactions.

关键词： Quercus robur L Seeds Figure NADH

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Geographic-Scale Coffee Cherry Counting with Smartphones and Deep Learning

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Plant Phenomics 2024年第2期6卷 390-400页

作者： Juan Camilo Rivera-Palacio Christian Bunn eric Rahn Daisy Little-savage Paul Günter Schmidt Masahiro Ryo Leibniz Centre for Agricultural Landscape Research(ZALF) Müncheberg15374Germany Alliance of Bioversity International and CIAT Rome00153Italy Brandenburg University of Technology Cottbus-Senftenberg Cottbus03046Germany Producers Direct LondonE28EXUK

Deep learning and computer vision,using remote sensing and drones,are 2 promising nondestructive methods for plant monitoring and ***,their applications are infeasible for many crop systems under tree canopies,such as coffee crops,making it challenging to perform plant monitoring and phenotyping at a large spatial scale at a low *** study aims to develop a geographic-scale monitoring method for coffee cherry counting,supported by an artificial intelligence(AI)-powered citizen science *** approach uses basic smartphones to take a few pictures of coffee trees;2,968 trees were investigated with 8,904 pictures in Junin and Piura(Peru),Cauca,and Quindio(Colombia)in 2022,with the help of nearly 1,000 smallholder coffee ***,we trained and validated YOLO(You Only Look Once)v8 for detecting cherries in the dataset in *** average number of cherries per picture was multiplied by the number of branches to estimate the total number of cherries per *** model's performance in Peru showed an R^(2)of *** the model was tested in Colombia,where different varieties are grown in different biogeoclimatic conditions,the model showed an R^(2)of *** overall performance in both countries reached an R^(2)of *** results suggest that the method can be applied to much broader scales and is transferable to other varieties,countries,and *** our knowledge,this is the first AI-powered method for counting coffee cherries and has the potential for a geographic-scale,multiyear,photo-based phenotypic monitoring for coffee crops in low-income countries worldwide.

关键词： geographic learning scale coffee deep with cherry counting smartphones

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Activation of the pattern recognition receptor NOD1 augments colon cancer metastasis

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Protein & Cell 2020年第3期11卷 187-201页

作者： Henry Y.Jiang Sara Najmeh Guy Martel elyse MacFadden-Murphy Raquel Farias Paul savage Arielle Leone Lucie Roussel Jonathan Cools-Lartigue Stephen Gowing Julie Berube Betty Giannias France Bourdeau Carlos HFChan Jonathan D.Spicer Rebecca McClure Morag Park Simon Rousseau Lorenzo e.Ferri Thoracic and Upper GI Cancer Research Laboratories Research Institute of McGill University Health Centre1001 Decarie BoulevardBlock ELab#E02-4134MontrealQC H4A 3J1Canada Department of experimental Surgery and Department of Surgery McGill University1650 Cedar AvenueMontrealQC H3G 1A4Canada Meakins-Christie Laboratories Research Institute of McGill University Health Centre1001 Decarie BoulevardMontrealQC H4A 3J1Canada The Rosalind and Morris Goodman Cancer Research Centre McGill University1160 Pine AvenueMontrealQC H3A 1A3Canada Department of Surgery Roy J.and Lucille A.Carver College of MedicineUniversity of IowaUniversity of Iowa Hospitals and Clinics200 Hawkins DriveIowa CityIA 52242USA Department of Pathology Health Sciences North41 Ramsey Lake RoadSudburyONCanada

While emerging data suggest nucleotide oligomerization domain receptor 1(NOD1),a cytoplasmic pattern recognition receptor,may play an important and complementary role in the immune response to bacterial infection,its role in cancer metastasis is entirely ***,we sought to determine the effects of NOD1 on ***1 expression in paired human primary colon cancer,human and murine colon cancer cells were determined using immunohistochemistry and immunoblotting(WB).Clinical significance of NOD1 was assessed using TCGA survival data.A series of in vitro and in vivo functional assays,including adhesion,migration,and metastasis,was conducted to assess the effect of NOD1.C12-ie-DAP,a highly selective NOD1 ligand derived from gram-negative bacteria,was used to activate ***130,a specific NOD1 inhibitor,was used to block C12-ie-DAP *** knockdown(KD)of NOD1 in human colon cancer cells(HT29)was constructed with shRNA lentiviral transduction and the functional assays were thus ***,the predominant signaling pathway of NOD1-activation was identified using WB and functional assays in the presence of specific kinase *** data demonstrate that NOD1 is highly expressed in human colorectal cancer(CRC)and human and murine CRC cell ***,we demonstrate that this increased NOD1 expression negatively impacts survival in patients with ***,we identify NOD1 activation by C12-ie-DAP augments CRC cell adhesion,migration and *** effects are predominantly mediated via the p38 mitogen activated protein kinase(MAPK)*** is the first study implicating NOD1 in cancer metastasis,and thus identifying this receptor as a putative therapeutic target.

关键词： NOD1 ie-DAP ML130 colon cancer metastasis cancer-extracellular matrix adhesion cancer migration p38 MAPK activation intravital microscopy survival analysis

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Conceptual design of a 15-TW pulsed-power accelerator for high-energy-densityephysics experiments

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Matter and Radiation at extremes 2017年第4期2卷 204-223页

作者： R.B.Spielman D.H.Froula G.Brent e.M.Campbell D.B.Reisman M.e.savage M.J.Shoup III W.A.Stygar M.L.Wisher Laboratory for Laser energetics University of RochesterRochesterNY14623USA Sandia National Laboratories AlbuquerqueNM 87185USA

We have developed a conceptual design of a 15-TW pulsed-power accelerator based on the linear-transformer-driver(LTD)architecture described by Stygar[*** et al.,*** *** 18,110401(2015)].The driver will allow multiple,high-energy-density experiments per day in a university environment and,at the same time,will enable both fundamental and integrated experiments that are scalable to larger *** this design,many individual energy storage units(bricks),each composed of two capacitors and one switch,directly drive the target load without additional pulse *** LTD modules in parallel drive the *** module consists of 16 LTD cavities connected in series,where each cavity is powered by 22 bricks connected in *** design stores up to 2.75 MJ and delivers up to 15 TW in 100 ns to the constant-impedance,water-insulated radial transmission *** transmission lines in turn deliver a peak current as high as 12.5 MA to the physics *** maximize its experimental value and flexibility,the accelerator is coupled to a modern,multibeam laser facility(four beams with up to 5 kJ in 10 ns and one beam with up to 2.6 kJ in 100 ps or less)that can provide auxiliary heating of the physics *** lasers also enable advanced diagnostic techniques such as X-ray Thomson scattering and multiframe and three-dimensional *** coupled accelerator-laser facility will be the first of its kind and be capable of conducting unprecedented high-energy-densityephysics experiments.

关键词： Pulsed power accelerator High energy density physics Conceptual design

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水热法处理微藻制备液态生物燃料

水热法处理微藻制备液态生物燃料

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中国化学会第28届学术年会

作者：段培高 Phillip e.savage 河南理工大学 University of Michigan 3074 H.H Dow Building2300 Hayward St.Ann ArborMI 48109

＜正＞藻类生物质因其需要较少的土地生长面积以及比陆地生物质具有更高的能量密度,且不像谷物类乙醇或者豆科类生物柴油那样涉及食物与能源竞争而成为一种可再生液体燃料非常有吸引

关键词：微藻水热液化氢化改质生物燃料

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植物细胞杂种

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新疆农业科学 1980年第6期 46-48页

作者： N.R.Ringertz ,R.e.savage ,刘杰龙

同动物细胞一样,植物细胞离解了细胞壁也能融合.植物细胞融合,无论是种内或种间的,都是可能的,而且产生的异核体能够存活并再生细胞壁和重新复制.植物细胞有两个优点是动物细胞所不能比拟的,那就是植物可以培养单倍体细胞,可以从单个的... 详细信息

同动物细胞一样,植物细胞离解了细胞壁也能融合.植物细胞融合,无论是种内或种间的,都是可能的,而且产生的异核体能够存活并再生细胞壁和重新复制.植物细胞有两个优点是动物细胞所不能比拟的,那就是植物可以培养单倍体细胞,可以从单个的体细胞成长为有机体.

关键词：细胞杂种细胞壁细胞融合动物细胞原生质体有性杂种有色体质体

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根据新西兰从消减至走滑的板块边界转换带的地方震来研究地震各向异性

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世界地震译丛 2001年第4期32卷 1-22页

作者： e.Audoine M.K.savage K.Gledhill 万登堡云南省地震局

用剪切波分裂法研究了消减带(新西兰北岛南半部)及其向倾斜转换断裂的转换带(南岛北部马尔博罗地区)地壳和上地幔中的各向异性。在马尔博罗,延迟时间几乎不随深度而增加,最可能的是,本研究所用的高频震相主要反映了岩石层的各向异性。... 详细信息

用剪切波分裂法研究了消减带(新西兰北岛南半部)及其向倾斜转换断裂的转换带(南岛北部马尔博罗地区)地壳和上地幔中的各向异性。在马尔博罗,延迟时间几乎不随深度而增加,最可能的是,本研究所用的高频震相主要反映了岩石层的各向异性。在马尔博罗断层系中部,快波偏振与断层近似平行。各向异性是由于在马尔博罗断层系之下50～80 km 处存在(30±10)km 厚的变质的片岩(榴辉岩)引起的。在马尔博罗断层系边缘,快波偏振平行于最大压应力方向,与地壳中由裂纹引起的各向异性一致。根据 SKS 震相推断出的地幔中与岛弧一样宽的剪切带,看来在地壳内发生在较窄的区内。在北岛的南半部,所有深度地震的快波偏振都平行于海库兰奇消减带和断层的走向。偏振性质和主要取自地幔的 SKS 震相的性质很相似。这表明,岩石层和上地慢具有一致的走滑剪切形变。对延迟时间随深度增加的地幔,我们计算出在软流层上部200 km 中速度各向异性为(1.2±0.3)%。为了与SKS 延迟时间匹配,这个结果要求直至(580±100)km 的深度都存在各向异性物质,或要求各向异性随深度而变化,或者分裂与频率相关。

关键词：地震各向异性板块边界消减带转换带

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杂种细胞

杂种细胞

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作者： N.R.·林格兹(N.R. Ringertz) R.e.·萨维奇(R.e. savage)

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expert consensus on the use of human serum albumin in adult cardiac surgery

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Chinese Medical Journal 2023年第10期136卷 1135-1143页

作者： Fei Xiang Fuhua Huang Jiapeng Huang Xin Li Nianguo Dong Yingbin Xiao Qiang Zhao Liqiong Xiao Haitao Zhang CuiZhang Zhaoyun Cheng Liangwan Chen Jimei Chen Huishan Wang Yingqiang Guo Nan Liu Zhe Luo Xiaotong Hou Bingyang Ji Rong Zhao Zhenxiao Jin Robert savage Yang Zhao Zhe Zheng Xin Chen on behalf of Chinese Association of Cardiovascular Surgeons Chinese Society of Thoracic and Cardiovascular Surgery Chinese Society of Cardiothoracic and Vascular Anesthesiology Department of Thoracic and Cardiovascular Surgery Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu 210006China Department of Anesthesiology and Perioperative Medicine University of LouisvilleLouisvilleKentucky 40292United States Department of Cardiovascular Surgery Zhongshan HospitalFudan UniversityShanghai 200031China Department of Cardiovascular Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430000China Department of Cardiovascular Surgery the Second Affiliated HospitalArmy Medical UniversityChongqing 400037China Department of Cardiovascular Surgery Ruijin HospitalShanghai Jiaotong University School of MedicineShanghai 200031China Department of Critical Care Fuwai HospitalChinese Academy of Medical SciencesBeijing 100033China Department of Critical Care Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu 210006China Department of Cardiac Surgery People’s Hospital of Henan ProvincePeople’s Hospital of Zhengzhou UniversityFuwai Central China Cardiovascular Disease HospitalZhengzhouHenan 450003China Department of Cardiac Surgery Fujian Medical University Union HospitalFuzhouFujian 350001China Department of Cardiovascular Surgery Guangdong Cardiovascular InstituteGuangdong Provincial Key Laboratory of South China Structural Heart DiseaseGuangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhouGuangdong 510050China Department of Cardiovascular Surgery General Hospital of Shenyang Military Area CommandShenyangLiaoning 110055China Department of Cardiovascular Surgery West China Hospital of Sichuan UniversityChengduSichuan 610041China Center for Cardiac Intensive Care Beijing Anzhen HospitalBeijing Institute of HeartLung and Blood Vessel DiseasesCapital Medical UniversityBeijing 102218China Department of Cardiopulmonary Bypass Fuwai HospitalChinese Academy of Medical SciencesBeijing 100033China Department of Cardiovascular Surgery Xijing HospitalFourth Militar

Introduction Albumin,which is a 65-kDa liver-synthesized protein,accounts for nearly 50%of total plasma protein and contributes to approximately 80%of intravascular oncotic *** helps maintain microvascular integrity,functions as an antioxidant,and transports hormones,fatty acid,bile salts,bilirubin,electrolytes(e.g.,calcium,magnesium,copper,zinc,et al.),and drugs.[1–3]Human serum albumin(HSA)is a sterile,liquid albumin product derived from large pools of human plasma by fractionation and *** medical use of HAS could date back to approximately the time of World War II.

关键词： Albumin drugs surgery

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ABSORPTION LINeS IN THe SPeCTRA OF THe QSO PKS 1448-232

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Chinese Science Bulletin 1983年第8期28卷 1075-1080页

作者：陈建生 DONALD C.MORTON BRUCe A.PeTeRSON ALAN e.WRIGHT DAVID L.JAUNCeY Beijing Observatory Academia Sinica Anglo-Australian Obserratory Mt. Stromlo and Siding Spring Observatory Australian National Radio Astronomical Observatory CSIRO Division of Radiophysics. OLD AND NeW OBSeRVATIONS savage Bolton and Wright found that the radio source PKS 1448-232 coincided with a stellar object of a magnitude about 16.4 having an ultraviolet excess. A lowresolution spectrum obtained with the Anglo-Australian 3.~m9 Telescope (AAT) confirmed this object to be a QSO with z_(em)=2.22 and revealed many absorption lines

I. OLD AND NeW OBSeRVATIONS savage, Bolton and Wright, found that the radio source PKS 1448-232 coincided with a stellar object of a magnitude about 16.4 having an ultraviolet excess. A lowresolution spectrum obtained with the Anglo-Australian 3.m9 Telescope （AAT） confirmed this object to be a QSO with zem=2.22, and revealed many absorption

关键词： Bolton Australian stellar ultraviolet Anglo savage magnitude excess Morton inverted

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