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Increased Drying Rate Lowers the Critical Water Content for Survival in embryonic Axes of english Oak (Quercus robur L.) Seeds

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Journal of Integrative Plant Biology 2011年第4期53卷 270-280页

作者： Tobias M.Ntuli william e.finch-savage Patricia Berjak Norman W.Pammenter Plant Germplasm Conservation Research School of Biological and Conservation SciencesUniversity of KwaZulu-NatalWestville CampusPrivate Bag X54001Durban 4000South Africa Department of Life and Consumer Sciences University of South AfricaPrivate Bag X6Florida 1710JohannesburgSouth Africa Warwick HRI Warwick UniversityWellesbourneWarwick CV35 9EFUK Plant Germplasm Conservation Research School of Biological and Conservation SciencesUniversity of KwaZulu-NatalWestville

The potential to cryopreserve embryonic axes of desiccation-sensitive（recalcitrant） seeds is limited by damage during the desiccation necessary for low temperature survival,but the basis of this injury and how to reduce it is not well *** effects of drying rate on the viability,respiratory metabolism and free radical-mediated processes were therefore investigated during dehydration of Quercus robur L embryonic ***,assessed by evidence of germination and tetrazolium staining,showed a sharp decline at 0.27 and 0.8 g/g during rapid（〈12 h） or slow（3d） dehydration,*** dehydration therefore lowered the critical water content for *** any given water content rapid dehydration was associated with higher activities of the free radical processing enzymes,superoxide dismutase,catalase and glutathione reductase and lower levels of hydroperoxide and membrane *** dehydration was also associated with lower malate dehydrogenase activity,and a reduced decline in phosphofructokinase activity and in levels of the oxidized form of nicotinamide *** may have contributed to increased damage during slow dehydration,since viability declined even in hydrated storage after 3 *** results presented are consistent with rapid dehydration reducing the accumulation of damage resulting from desiccation induced aqueous-based deleterious reactions.

关键词： Quercus robur L Seeds Figure NADH

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LeAD POISONING IN ANCIeNT ROMe: THe STATe OF THe QUeSTION

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Journal of Ancient Civilizations 2022年第2期37卷 225-246,276页

作者： Stanley M.Burstein Caleb e.finch California State University Los Angeles The University of Southern California

Introduction Lead pollution as a significant health hazard appears frequently in the news,sometimes spectacularly so as in the case of the recent contamination of the watersupplyof the cityof Flint,Michiganbecause of itsuse inlead pipes in the system.'As a result,it is easy to assume that environmental lead pollution is a recent problem,but that is not the *** exposure is,in fact.

关键词： pollution Flint pipes

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Correspondence of bubble size and frother partitioning in flotation

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Journal of Central South University 2014年第6期21卷 2383-2390页

作者：张炜 Jan e.Nesset James A.finch Mining & Mineral Resources Division Department of Business AdministrationChinalco China Copper Corporation Limited Department of Mining and Materials engineering McGill UniversityMontrealQCH3A 0C5Canada

The size of bubbles created in the flotation process is of great importance to the efficiency of the mineral separation ***,it is believed that frother transport between phases is perhaps the most important reason for the interactive nature of the phenomena occurring in the bulk and froth phases in flotation,as frother adsorbed in the surface of rising bubbles is removed from the bulk phase and then released into the froth as a fraction of the bubbles *** causes the increased concentration in the froth compared to the bulk concentration,named as frother *** reflects the adsorption of frother on bubbles and how to influence bubble size is not *** currently exists no such a topic aiming to link these two key *** fill this vacancy,the correspondence between bubble size and frother partitioning was *** size was measured by sampling-for-imaging(SFI)*** total organic carbon(TOC)analysis to measure the frother partitioning between froth and bulk phases was *** have shown,with no exceptions including four different frothers,higher frother concentration is in the bulk than in the *** results also show strong partitioning giving an increase in bubble size which implies there is a compelling relationship between these two,represented by CFroth/CBulk and *** CFroth/CBulkand D32 curves show similar exponential decay relationships as a function of added frother in the system,strongly suggesting that the frother concentration gradient between the bulk solution and the bubble interface is the driving force contributing to bubble size reduction.

关键词： flotation frother bubble size frother partitioning total organic carbon (TOC) analysis concentration gradient

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A novel approach to prevent bubble coalescence during measurement of bubble size in flotation

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Journal of Central South University 2014年第1期21卷 338-343页

作者：张炜 Jan e.Nesset James A.finch Mining and Mineral Resources Division Department of Business AdministrationChinalco China Copper Corporation Limited Department of Mining and Materials engineering McGill University

effect of frothers in preventing bubble coalescence during flotation of minerals has long been *** evaluate the performance of a frother,an apparatus to measure the bubble size is a basic *** Bubble Size Analyzer(MBSA) or bubble viewer that has been developed and completed by McGill University's Mineral Processing Group during the last decade is a unique instrument to serve this *** parameters which are thought to influence the bubble size measurements by McGill bubble viewer include water quality and frother concentration in the *** show that there is no difference in Sauter mean(D32) when tap or de-ionized water was used instead of process ***,the frother concentration,in this research DowFroth 250(DF250),inside the chamber exhibited a pronounced effect on bubble *** concentration below a certain point can not prevent coalescence inside the chamber and therefore caution must be taken in plant *** was also noted that the frother concentration which has been so far practiced in plant measurements(CCC75-CCC95) is high enough to prevent coalescence with the bubble viewer.

关键词： flotation frother bubble size bubble coalescence

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Bubble size as a function of some situational variables in mechanical flotation machines

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Journal of Central South University 2014年第2期21卷 720-727页

The specific results of the work investigating the effect of gas density and water temperature on bubble size were *** were surrogate variables designed to investigate the effect of viscosity(varying water temperature) and altitude(varying gas density).The results show that there is a measurable but relatively small effect of gas density on bubble *** D32 is revealed to increase proportionally as(ρ0/ρg)*** projected impact on flotation kinetics at 4500 m versus sea level is small,of the order of 0.5% recovery loss for a bank of eight flotation *** effect of water temperature(4-40 °C) on bubble size is more significant than gas *** relationship correlates with water viscosity values quite closely.A finding that D32 increases proportionally as(μ/μ20)0.776 highlights the importance of accounting for viscosity effects if,for example,large process temperature fluctuations or deviation from design/test conditions are expected.

关键词： flotation frother bubble size viscosity altitude

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effect of some operational variables on bubble size in a pilot-scale mechanical flotation machine

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Journal of Central South University 2014年第3期21卷 1077-1084页

作者：张炜 J.e.Nesset J.A.finch Mining and Mineral Resources Division Department of Business AdministrationChinalco China Copper Corporation Limited Department of Mining and Materials engineering McGill University

This work aims to provide a relationship of how the key operational variables of frother type and impeller speed affect the size of bubble （D32）. The study was performed using pilot-scale equipment （0.8 m^3） that is up to two orders of magnitude larger than equipment used for studies performed to date by others, and incorporated the key process variables of frother type and impeller speed. The results show that each frother family exhibits a unique CCC95-HLB relationship dependent on n （number of C-atoms in alkyl group） and m （number of propylene oxide group）. empirical models were developed to predict CCC95 from HLB associated with other two parameters a and ft. The impeller speed-bubble size tests show that D32 is unaffected by increased impeller tip speed across the range of 4.6 to 9.2 m/s （representing the industrial operating range）, although D32 starts to increase below 4.6 m/s. The finding is valid for both coalescing and non-coalescing conditions. The results suggest that the bubble size and bubble size distribution （BSD） being created do not change with increasing impeller speed in the quiescent zone of the flotation.

关键词： flotation bubble size operational variables critical coalescence concentration hydrophile-lipophile balance impellerspeed

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effect of solids on pulp and froth properties in flotation

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Journal of Central South University 2014年第4期21卷 1461-1469页

作者：张炜 James A.finch Mining & Mineral Resources Division Department of Business Administration Chinalco China Copper Corporation Limited Department of Mining and Materials engineering McGill University

Froth flotation is a widely used process of particle separation exploiting differences in surface properties. It is important to point out that overall flotation performance(grade and recovery) is a consequence of the quality and quantity of the solid particles collected from the pulp phase, transported into the froth phase, and surviving as bubble-particle aggregates into the overflow. This work will focus on studying these phenomena and will incorporate the effects of particle hydrophobicities in the 3-phase system. Solids are classed as either hydrophilic non-sulphide gangue(e.g. silica, talc), hydrophilic sulphide(e.g. pyrite), or hydrophobic sulphide(e.g. sphalerite). Talc is a surface-active species of gangue that has been shown to behave differently from silica(frother adsorbs on the surface of talc particles). Both are common components of ores and will be studied in detail. The focus of this work is to investigate the role of solids on pulp hydrodynamics, froth bubble coalescence intensity, water overflow rate with solids present, and in particular, the interactions between solids, frother and gas on the gas dispersion parameters. The results show that in the pulp zone there is no effect of solids on bubble size and gas holdup; in the froth zone, although hydrophilic particles solely do not effect on the water overflow rate, hydrophobic particles produce higher intensity of rates on water overflow and bubble coalescence, and many be attributed to the water reattachment.

关键词： flotation frothers bubble size coalescence gas holdup hydrophobicity

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Alpine Activity Patterns of Mitopus morio(Fabricius, 1779) are Induced by Variations in Temperature and Humidity at Different Scales in Central Norway

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Journal of Mountain Science 2014年第3期11卷 644-655页

作者： Nils HeIN Roland PAPe Oliver-D. finch Jorg LOFFLeR Department of C-eography University of Bonn Meckenheimer AUee 166 D-53115 Bonn Germany Achtern Nordpol 8 D-26180 Rastede Germany

Our research addresses questions about how micro-climate affects activity abundance of a common and widespread harvestman in an alpine ecosystem. Activity patterns of the Harvestman Mitopus morio(Fabricius, 1779) were studied along different alpine gradients in the central Norwegian Scandes. Within a nested design, we surveyed 18 alpine habitats with pitfall traps and microclimatological equipment along oceanic-continental, two elevational, and(fine-scaled) microtopographic gradients. Sites in the oceanic region of the Scandes showed generally higher abundance of M. morio than sites in the continental region. Furthermore, along the elevational gradient, middle-alpine sites showed higher abundances than low-alpine sites. These general patterns are best explained by higher humidity in the oceanic region and in the middlealpine belt. Focusing at a finer scale, i.e. one elevational level within each region, revealed partly opposing activity patterns within relatively short distances. While in the western middle-alpine belt these patterns were best explained by humidityrelated measures but now with higher activity abundance during drier conditions, in the drier eastern middle-alpine belt heat sums rather than humidity were found to be the best explanatoryvariables for the observed patterns. Hence, our results imply a pronounced different reaction of the two populations towards climatic variables that partly even contradict the previously described general pattern. Regardless whether these differences in activity abundance in M. morio are a form of phenotypic plasticity or adaptation, our findings stress the importance of detailed autecological knowledge combined with fine-scaled climatic measurements when aiming at predictions about possible future ecosystem structures and spatiotemporal phenomena. M. morio proves to be an ideal biogeographic model organism for understanding spatio-temporal responses of alpine ecosystems under modified climatic conditions.

关键词： Climate gradients Opiliones Arctic-alpine ecosystems High mountains Scandinavia

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Operations now : 2nd ed.

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丛书名： The McGraw-Hill/Irwin series operations management

2006年

作者： Byron J. finch.

来源：畅想之星图书光盘版（南... 评论

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Activation of the pattern recognition receptor NOD1 augments colon cancer metastasis

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Protein & Cell 2020年第3期11卷 187-201页

作者： Henry Y.Jiang Sara Najmeh Guy Martel elyse MacFadden-Murphy Raquel Farias Paul savage Arielle Leone Lucie Roussel Jonathan Cools-Lartigue Stephen Gowing Julie Berube Betty Giannias France Bourdeau Carlos HFChan Jonathan D.Spicer Rebecca McClure Morag Park Simon Rousseau Lorenzo e.Ferri Thoracic and Upper GI Cancer Research Laboratories Research Institute of McGill University Health Centre1001 Decarie BoulevardBlock ELab#E02-4134MontrealQC H4A 3J1Canada Department of experimental Surgery and Department of Surgery McGill University1650 Cedar AvenueMontrealQC H3G 1A4Canada Meakins-Christie Laboratories Research Institute of McGill University Health Centre1001 Decarie BoulevardMontrealQC H4A 3J1Canada The Rosalind and Morris Goodman Cancer Research Centre McGill University1160 Pine AvenueMontrealQC H3A 1A3Canada Department of Surgery Roy J.and Lucille A.Carver College of MedicineUniversity of IowaUniversity of Iowa Hospitals and Clinics200 Hawkins DriveIowa CityIA 52242USA Department of Pathology Health Sciences North41 Ramsey Lake RoadSudburyONCanada

While emerging data suggest nucleotide oligomerization domain receptor 1(NOD1),a cytoplasmic pattern recognition receptor,may play an important and complementary role in the immune response to bacterial infection,its role in cancer metastasis is entirely ***,we sought to determine the effects of NOD1 on ***1 expression in paired human primary colon cancer,human and murine colon cancer cells were determined using immunohistochemistry and immunoblotting(WB).Clinical significance of NOD1 was assessed using TCGA survival data.A series of in vitro and in vivo functional assays,including adhesion,migration,and metastasis,was conducted to assess the effect of NOD1.C12-ie-DAP,a highly selective NOD1 ligand derived from gram-negative bacteria,was used to activate ***130,a specific NOD1 inhibitor,was used to block C12-ie-DAP *** knockdown(KD)of NOD1 in human colon cancer cells(HT29)was constructed with shRNA lentiviral transduction and the functional assays were thus ***,the predominant signaling pathway of NOD1-activation was identified using WB and functional assays in the presence of specific kinase *** data demonstrate that NOD1 is highly expressed in human colorectal cancer(CRC)and human and murine CRC cell ***,we demonstrate that this increased NOD1 expression negatively impacts survival in patients with ***,we identify NOD1 activation by C12-ie-DAP augments CRC cell adhesion,migration and *** effects are predominantly mediated via the p38 mitogen activated protein kinase(MAPK)*** is the first study implicating NOD1 in cancer metastasis,and thus identifying this receptor as a putative therapeutic target.

关键词： NOD1 ie-DAP ML130 colon cancer metastasis cancer-extracellular matrix adhesion cancer migration p38 MAPK activation intravital microscopy survival analysis

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