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Robust Regularization Design of Graph Neural Networks Against Adversarial Attacks Based on Lyapunov Theory

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Chinese Journal of Electronics 2024年第3期33卷 732-741页

作者： wenjie yan Ziqi LI Yongjun QI School of Artificial Intelligence Hebei University of Technology School of Computer Science and Engineering of North China Institute of Aerospace Engineering

The robustness of graph neural networks（GNNs） is a critical research topic in deep *** researchers have designed regularization methods to enhance the robustness of neural networks,but there is a lack of theoretical analysis on the principle of *** order to tackle the weakness of current robustness designing methods,this paper gives new insights into how to guarantee the robustness of GNNs.A novel regularization strategy named Lya-Reg is designed to guarantee the robustness of GNNs by Lyapunov *** results give new insights into how regularization can mitigate the various adversarial effects on different graph *** experiments on various public datasets demonstrate that the proposed regularization method is more robust than the state-of-theart methods such as L1-norm,L2-norm,L2-norm,Pro-GNN,PA-GNN and GARNET against various types of graph adversarial attacks.

关键词： Training Deep learning Garnets Robustness Graph neural networks

An Interactive Perception Method Based Collaborative Rating Prediction Algorithm

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Chinese Journal of Electronics 2023年第1期32卷 97-110页

作者： yan wenjie ZHANG Jiahao LI Ziqi School of Artificial Intelligence Hebei University of Technology

To solve the rating prediction problems of low accuracy and data sparsity on different datasets,we propose an interactive perception method based collaborative rating prediction algorithm named DCAE-MF,by fusing dual convolutional autoencoder(DCAE) and probability matrix factorization(PMF). Deep latent representations of users and items are captured simultaneously by DCAE and are deeply integrated with PMF to collaboratively make rating predictions based on the known rating history of users. A global multi-angle collaborative optimization learning method is developed to effectively optimize all the parameters of DCAE-MF. Extensive experiments are performed on seven real-world datasets to demonstrate the superiority of DCAE-MF on key rating accuracy metrics of the root mean squared error(RMSE) and mean absolute error(MAE).

关键词： Measurement Learning systems Collaboration Prediction algorithms History Optimization

High-performance Ti_(3)C_(2)T_(x)achieved by polyaniline intercalation and gelatinization as a high-energy cathode for zinc-ion capacitor

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Nano Research 2024年第6期17卷 5305-5316页

作者： Peng Liao ZiYu Geng Xin Zhang wenjie yan Zenghui Qiu Haijun Xu College of Mathematics and Physics Beijing University of Chemical TechnologyBeijing 100029China

The actual manufacture of supercapacitors(SCs)is restricted by the inadequate energy density,and the energy density of devices can be properly promoted by assembling zinc-ion capacitors(ZICs)which used capacitive cathode and battery-type ***-dimensional(2D)MXene has brought great focuses in the electrode research on the foundation of large redox-active surface,but the specific capacitance is still affected by the tight stacking of ***_(3)C_(2)T_(x)@polyaniline(PANI)heterostructures are prepared by uniformly depositing the conductive polymer PANI nanorods as the intercalation agent into the external of Ti_(3)C_(2)T_(x)nanosheets to inhibit ***,by using graphene oxide(GO)-assisted low-temperature hydrothermal self-assembly manufacture,2D heterostructures are assembled into the three-dimensional(3D)porous crosslinked Ti_(3)C_(2)T_(x)@PANI-reduced graphene oxide(RGO)*** to the synergistic work of PANI nanorods,Ti_(3)C_(2)T_(X)nanosheets,and 3D crosslinking frameworks of RGO to match capacitive and battery effects,3D porous hierarchical Ti_(3)C_(2)T_(x)@PANI-RGO heterostructure hydrogels have rich ion transport channels,a large number of active sites,and excellent reaction *** is assembled by using Ti_(3)C_(2)T_(x)@PANI-RGO heterostructure hydrogels as cathodes and zinc foil as *** this work,Ti_(3)C_(2)T_(x)@PANI-RGO//Zn ZIC exhibits a wide working window(2.0 V),marked specific capacitance(589.89 F·g^(−1)at 0.5 A·g−1),salient energy density(327.71 Wh·kg^(−1)at 513.61 W·kg^(−1)and 192.20 Wh·kg^(−1)at 13,005.87 W·kg^(−1)),and durable cycling stability(97.87%capacitance retention after 10,000 cycles at 10 A·g^(−1)).This study emphasizes the device design of ZICs and the broad prospect of Ti_(3)C_(2)T_(x)-based hydrogels as viable cathodes for ZICs.

关键词： polyaniline(PANI) Ti_(3)C_(2)T_(x)@PANI heterostructure intercalation process three-dimensional(3D)porous hydrogel high energy density zinc-ion capacitor

Cloning, characterization and expression analysis of a microsomal glutathione S-transferase gene from the seagrass Zostera marina

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Acta Oceanologica Sinica 2019年第10期38卷 111-115页

作者： wenjie yan Jiao Liu Samphal Seng Bin Zhou Kuke Ding Department of Marine Ecology College of Marine Life SciencesOcean University of ChinaQingdao 266003China Institute of Oceanology Chinese Academy of SciencesQingdao 266071China Faculty of Fisheries&Aquaculture Royal University of AgriculturePhnom Penh 12101Cambodia National Institute for Radiological Protection Chinese Center for Disease Control and PreventionBeijing 100088China Key Laboratory of Radiological Protection and Nuclear Emergency Chinese Center for Disease Control and PreventionBeijing 100088China

The response of glutathione S-transferase(GST)in Zostera marina to temperature variation was analyzed at molecular level by cloning the microsomal GST gene and texting the microsomal GST expression regularity under different *** speaking,express ZmGST in Escherichia coli,then purify the recombinant protein and make the thermal stability ***,the experiments were carried out to provide a theoretical basis for the further elaboration to the population degradation mechanisms of *** conclusion,the thermostability and the response of ZmGST gene to temperature changes can determine its temperature tolerance range,and affect its resilience in turn.

关键词： Zostera marina antioxidant enzyme glutathione S-transferase (GST) temperature enzyme activity

Effects of silkworm pupa protein on apoptosis and energy metabolism in human colon cancer DLD-1 cells

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Food Science and Human Wellness 2022年第5期11卷 1171-1176页

作者： Xiaojiao Ji Jing Wang Aijin Ma Duo Feng Yue He wenjie yan College of Biochemical Engineering Beijing Union UniversityBeijing 100101China Institute of Food and Nutrition Development Ministry of Agriculture and Rural AffairsBeijing 100125China College of Food and Health Beijing Technology and Business UniversityBeijing 100048China

Objective:To investigate the effects of silkworm pupa(Bombyx mori) protein(SPP) on cell proliferation,apoptosis and energy metabolism in human colon cancer cells ***:CCK-8 was used to detect cell proliferation rate after 72 h of cell culture for the control group(normal cultured DLD-1 cells) and SPP dose groups;Annexin-V/PI was applied to observe cell apoptosis;XFe24 Extracellular Flux Analyzer was used to detect cell mitochondrial respiratory function and glycolytic ***:Comparing with the control,SPP significantly inhibited the proliferation of DLD-1 cells with all the dosage tested(P <0.01);flow cytometry showed that SPP significantly promoted apoptosis(P<0.05).Additionally,SPP could significantly inhibited mitochondrial metabolism and glycolysis of DLD-1 cells and decreased cell energy metabolism in all groups treated with different ***:SPP can cause oxidative damage,promote apoptosis,and reduce mitochondrial respiratory and glycolysis rate in colon cancer DLD-1 cells,which reveals that SPP has the potential to serve as the anti-cancer drugs in the future,but further experimental evidence is needed.

关键词： Colon cancer DLD-1 cells Silkworm pupa protein Apoptosis Mitochondria Glycolysis

Generating 0.42 THz radiation from a second harmonic gyrotron

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Chinese Science Bulletin 2011年第28期56卷 3572-3574页

作者： FU wenjie yan yang LI XiaoYun YUAN XueSong LIU ShengGang Terahertz Research Center School of Physical Electronics University of Electronic Science and Technology of China Chengdu 610054 China

Gyrotrons are high powered coherent electromagnetic radiation sources, and are considered to be available powerful sources that have the potential to bridge the so-called terahertz gap. In the University of Electronic Science and Technology of China, a second harmonic gyrotron has been designed, manufactured, and tested. The gyrotron generated radiation at a 0.423 THz frequency in 5μs pulses with an 8.1 Tesla magnetic field, with a power per pulse of about 4.4 kW. To date this is the highest frequency recorded for vacuum electronic devices in China. The gyrotron design, operation and measurements are presented.

关键词： THz辐射二次谐波回旋管电子科技大学真空电子器件中国科技脉冲功率出现频率

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天麻生物活性成分及功效研究进展

食品科学 2023年第17期44卷 332-340页

作者：段昊闫文杰北京联合大学生物化学工程学院生物活性物质与功能食品北京市重点实验室北京100191

天麻是一种食药兼备的植物,主要含有天麻素、派立辛、对羟基苯甲醇、多糖等生物活性成分,具有较好的改善记忆、助眠、抗癫痫等保健功能。目前,围绕天麻相关的生物活性成分及功效研究已取得了较多进展,但缺乏系统总结。因此,本文归纳了... 详细信息

天麻是一种食药兼备的植物,主要含有天麻素、派立辛、对羟基苯甲醇、多糖等生物活性成分,具有较好的改善记忆、助眠、抗癫痫等保健功能。目前,围绕天麻相关的生物活性成分及功效研究已取得了较多进展,但缺乏系统总结。因此,本文归纳了天麻在普通食品和保健食品等领域的使用依据,综述了天麻中主要的生物活性成分、药理作用及作用机制的研究进展,以期为天麻在食品领域的合规性应用及对其功效的深入研究提供参考。

关键词：天麻使用依据生物活性成分功效作用机制

Silkworm pupa peptide ameliorates dextrose sodium sulfate-induced colitis by enhancing gut barriers and modifying gut flora

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Food Science and Human Wellness 2024年

作者： Yaxi Zhou Diandian Wang Hao Duan Shiqi Zhou Jinhong Guo Yu Guo Jian Zhao wenjie yan Beijing Key Laboratory of Bioactive Substances and Functional Food， College of Biochemical Engineering， Beijing Union University

The anti-inflammatory properties of silkworm pupa peptide (SPP) have been recognized for their potential benefits in colitis treatment. However， the underlying mechanism of SPP in colitis animal models remains unclear. The objective of our work was to investigate the improving effect and the mechanism of action of SPP on a mouse model of dextrose sodium sulfate (DSS)-induced colitis. The findings suggested that SPP effectively eased ulcerative colitis (UC) symptoms in mice by decreasing disease activity index， ameliorating histopathological injury， and decreasing serum and colonic markers of inflammation. In addition， our research findings demonstrated that SPP restored intestinal barrier function by increasing the production of tight junction proteins such as zonula occludens-1 (ZO-1)， claudin-1， claudin-3， occludin， and adherens junction protein E-cadherin1. Further， SPP supplementation enhanced the concentration of short-chain fatty acids and positively altered the makeup of the gut bacteria in the mice’s gut. These findings underscore SPP’s ability to slow the progression of colitis and point to its possible use as a functional component in dietary supplements for the prevention of early-stage colitis.

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缓解视疲劳功能的原料及其功效成分研究进展

食品工业科技 2023年第13期44卷 417-424页

作者：段昊闫文杰北京联合大学生物化学工程学院生物活性物质与功能食品北京市重点实验室北京100023

过度用眼、环境过于干燥或受其他因素干扰时,容易导致眼睛长时间调节屈光,引发视疲劳,其主要表现为:经常性出现视物模糊、眼部酸胀、干涩、流泪等眼部不适感。研究表明,补充适宜的物质有助于缓解视疲劳。目前,围绕视疲劳及眼部健康相关... 详细信息

过度用眼、环境过于干燥或受其他因素干扰时,容易导致眼睛长时间调节屈光,引发视疲劳,其主要表现为:经常性出现视物模糊、眼部酸胀、干涩、流泪等眼部不适感。研究表明,补充适宜的物质有助于缓解视疲劳。目前,围绕视疲劳及眼部健康相关的研究已取得了一定的进展,但缺乏系统总结。因此,本文综述了视疲劳产生的生理学机制,以国家特殊食品信息查询平台为数据检索工具,对已获批缓解视疲劳功能保健食品的原料及标志性成分进行了较为系统的统计、分类及分析,并对具有缓解视疲劳功能的功效成分研究进展进行了较为系统的综述,以期为缓解视疲劳保健食品的开发提供一定的参考依据和启发。

关键词：视疲劳保健食品原料机制功效成分