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Effect of Xiaochuanping powder on the inflammatory response and airway remodeling in asthmatic rats

Journal of Traditional Chinese Medicine 2018年第1期38卷 61-66页

作者： Zhou Tao Zhang Nianzhi Hu Die wang wendong Xu Shunfu Chen Xu Department of biochemistry and molecular biology Anhui University of Chinese Medicine Department of respiratory medicine the First Affiliated Hospital of Anhui University of Chinese Medicine

OBJECTIVE： To observe the effect of Xiaochuanping powder （XP）, a traditional Chinese prescrip- tion for the treatment of cough and asthma, on serum concentrations of eosinophil cationic protein （ECP）, tumor necrosis factor （TNF）-a, and interleu- kin （IL）-4, eosinophil counts, as well as expression of matrix metalloproteinase （MMP）-9, tissue inhibi- tor of metalloproteinase （TIMP）-I in the lung tissues of asthmatic rats. METHODS： Sixty clean-grade Sprague-Dawley rats were divided randomly into six groups： normal control （NC）, asthma model, Guilong Kechuanning （GK） group, as well as high, intermediate-, and lowdose XP groups. Rats were sensitized with ovalbu- min （OVA） to trigger asthma. Serum concentrations of ECP, TNF-a and IL-4, eosinophil counts, as well as expression of MMP-9 and TIMP-1 in lung tissues were evaluated using an immunofluorescence method, mRNA expression of MMP-9 and TIMP-1 was determined using real-time quantitative poly- merase chain reaction. RESULTS： Compared with the asthma-model group, serum concentrations of ECP, TNF-a, and IL-4, and eosinophil counts decreased significantly in the high- and intermediate-dose XP groups and GK group （all P 〈 0.01）. Protein expression of MMP-9 and TIMP-1 decreased significantly in the high- and intermediate-dose XP groups and GK group （all P 〈 0.01）. Transcription of MMP-9 and TIMP-1 mRNA and the ratio of expression of MMP-9：TIMP-1 in lung tissue were significantly lower （P 〈 0.01）. CONCLUSION： XP can reduce TNF-a secretion, sup- press the infiltration/activation of eosinophils, re- duce serum concentrations of ECP and IL-4, reduce the protein and mRNA expression of MMP-9 and TIMP-1 in lung tissue, and regulate the balance between expression of MMP-9 and TIMP-1. In these ways, XP alleviated the inflammation and remodel- ing of the airways.

关键词： Asthma Airway remodeling Eosino- phils Eosinophil cationic protein Matrix metallo- proteinase 9 Tumor necrosis factor-alpha Tissue in- hibitor of metalloproteinase-1 Xiaochuanping powder

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The effect of solvent in evaporation-induced self-assembly：A case study of benzene periodic mesoporous organosilica

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中国科学：化学 2012年第1期42卷 114-115页

作者： wang wendong FAULKNER Daniel MOIR Jonathon OZIN Geoffrey A. Materials Chemistry Research Group Department of Chemistry University of Toronto 80 St. George Street Toronto M5S 3H6 Canada Department of Materials Science ＆ Engineering University of Toronto 184 College St Toronto M5S 3E4 Canada

Volatile organic solvents were considered to have little influence on the synthesis of mesostructured materials through evaporation-induced self-assembly(EISA),because upon evaporation they leave the sol and hence do not interfere with the self-assembly *** show here that the choice of solvent is crucial in the synthesis of thin films of phenylene-bridged periodic mesoporous organosilica(benzene PMO).Methanol is found to be a better solvent for the synthesis of thin films,whereas ethanol favors the formation of(HO)3Si-C6H4-Si(OH)3 crystals,the identity and structure of which is established by X-ray diffraction.A ternary reactant composition diagram is designed to visualize the relationship among multiple synthesis experiments and to guide the interpretation of experimental results and optimization of the quality of the periodic mesoporous organosilica *** study highlights the importance of solvent choice,a factor often neglected in *** expect it to inspire researchers to explore the effect of solvent in designing the synthesis of mesoporous materials.

关键词：溶剂蒸发介孔材料周期性自组装诱导挥发性有机溶剂苯案例

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Spontaneous imbibition characteristics of shale oil reservoir under the influence of osmosis

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International Journal of Coal Science & Technology 2022年第5期9卷 48-58页

作者： Yuliang Su Qinghao Sun wendong wang Xincheng Guo Jilong Xu Guanqun Li Xiugang Pu Wenzhong Han Zhannan Shi Key Laboratory of Unconventional Oil&Gas Development China University of Petroleum(East China)Ministry of EducationQingdao 266580China School of Petroleum Engineering China University of Petroleum(East China)Qingdao 266580China PetroChina Dagang Oilfield Company Tianjin 300280China

The spontaneous imbibition(SI)process in shale oil reservoirs is not only infuenced by capillary force,but also by the osmotic pressure between the fracturing fuid and formation water in the nanopores *** this study,experimental methods are used to investigate the mechanisms of osmosis in the SI,taking into account the presence of initial formation water in shale oil *** investigate the efect of osmosis,SI experiments were performed on the fne-grained felsic shale of the Qikou sag of Dagang ***-feld NMR testers and high-precision electronic balances are utilized for the measuring of oil–water *** results show that,when Sw≠0,high-salinity fuid SI can be divided into four stages:initial imbibition stage,drainage stage,secondary imbibition stage and stationary stage;when Sw=0,there is no drainage stage of high-salinity fuid SI;when Sw≠0 or Sw=0,low-salinity fuid SI can be called the“osmosis-enhanced SI”;and we have found that“newly formed pores or microfractures”as well as reducing salinity can promote *** article presents a systematic study of SI of shale oil reservoirs under the infuence of osmosis,which provide useful information for reservoir numerical simulation and development program design.

关键词： Shale oil Spontaneous imbibition Osmosis Water saturation Capillarity

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A NOVEL INTEREST COVERAGE METHOD BASED ON JENSEN-SHANNON DIVERGENCE IN SENSOR NETWORKS

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Journal of Electronics(China) 2007年第4期24卷 484-489页

作者： wang Yufeng wang wendong College of Telecommunications and Information Engineering Nanjin9 University of Posts and Telecommunications （ NUPT） Nanjin9 210003 China National Laboratory of Switching Technology ＆ Telecommunication Networks Beijing University of Posts and Telecommunications （ B UPT） Beijing 100875 China

In this paper, the idea of interest coverage is provided to form clusters in sensor network, which mean that the distance among data trends gathered by neighbor sensors is so small that, in some period, those sensors can be clustered, and certain sensor can be used to replace the cluster to form the virtual sensor network topology. In detail, the Jensen-Shannon Divergence (JSD) is used to characterize the distance among different distributions which represent the data trend of sensors. Then, based on JSD, a hierarchical clustering algorithm is provided to form the virtual sensor network topology. Simulation shows that the proposed approach gains more than 50% energy saving than Sta- tistical Aggregation Methods (SAM) which transmitted data gathered by sensor only when the differ- ence among data exceed certain threshold.

关键词： Sensor network Interest coverage Jensen-Shannon Divergence (JSD) Hierarchical clustering algorithm

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Phase Transitions and Seepage Characteristics during the Depletion Development of Deep Condensate Gas Reservoirs

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Energy Engineering 2024年第10期121卷 2797-2823页

作者： Qiang Liu Rujun wang Yintao Zhang Chong Sun Meichun Yang Yuliang Su wendong wang Ying Shi Zheng Chen Exploration and Development Technology Research and Development Center of Ultra-Deep Complex Oil and Gas Reservoirs Petro China Tarim Oilfield CompanyKorla841000China School of Petroleum Engineering China University of Petroleum(East China)Qingdao266580China

Deep condensate gas reservoirs exhibit highly complex and variable phase behaviors,making it crucial to understand the relationship between fluid phase states and flow *** study conducts a comprehensive analysis of the actual production process of the deep condensate gas well A1 in a certain oilfield in *** phase behavior analysis and CMG software simulations,the study systematically investigates phase transitions,viscosity,and density changes in the gas and liquid phases under different pressure conditions,with a reservoir temperature of 165°*** research covers three crucial depletion stages of the reservoir:single-phase flow,two-phase transition,and two-phase *** findings indicate that retrograde condensation occurs when the pressure falls below the dew point pressure,reachingmaximum condensate liquid production at around *** pressure decreases,gas phase density and viscosity gradually decrease,while liquid phase density and viscosity show an increasing *** the initial single-phase flow stage,maintaining a consistent gas-oil ratio is observed when both bottom-hole and reservoir pressures are higher than the dew point ***,a sudden drop in bottom-hole pressure below the dew point triggers the production of condensate oil,significantly reducing subsequent gas and oil *** the transitional two-phase flow stage,as the bottom-hole pressure further decreases,the reservoir exhibits a complex flow regime with coexisting areas of gas and *** the subsequent two-phase flow stage,when both bottom-hole and reservoir pressures are below the dew point pressure,a significant increase in the gas-oil ratio is *** reservoir manifests a two-phase flow regime,devoid of single-phase gas flow *** lowpressure conditions in deep condensate gas reservoirs,considerations include gas injection,gas lift,and cyclic gas injection and production in surrounding ***,techniques such as hot nitrogen or CO

关键词： Deep condensate gas reservoirs depletion development phase behavior percolation laws dynamic production analysis

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On the feasibility and efficacy of control traffic protection in software-defined networks

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Science China Chemistry 2015年第12期58卷 40-58页

作者： HU YanNan wang wendong GONG XiangYang QUE XiRong CHENG ShiDuan State Key Laboratory of Networking and Switching Technology Beijing University of Posts and Telecommunications

Software Defined Networking （SDN） is an emerging networking paradigm that assumes a logically centralized control plane separated from the data plane. Despite all its advantages, separating the control and data planes introduces new challenges regarding resilient communications between the two. That is, disconnec- tions between switches and their controllers could result in substantial packet loss and performance degradation. This paper addresses this challenge by studying the issue of control traffic protection in SDNs with arbitrary numbers of controllers. Specifically, we propose a control traffic protection scheme that combines both local rerouting and constrained reverse path forwarding protections, through which switches can locally react to fail- ures and redirect the control traffic using standby backup forwarding options. Our goal is then to find a set of primary routes for control traffic, called protected control network, where as many switches as possible can benefit from the proposed protection scheme. We formulate the protected control network problem, prove its NP-hardness, and develop an algorithm that reconciles proteetability and performance （e.g., switch-to-control latency）. Through extensive simulations based on real topologies, we show that our approach significantly im- proves protectability of control traffic. The results should help further the process of deploying SDN in real-world networks.

关键词： software-defined network protection control traffic resilience optimization

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Coverage Area Based Opportunistic Forwarding Algorithm in VANETs

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China Communications 2012年第12期9卷 56-67页

作者： Ding Yu wang wendong Gong Xiangyang Cui Yong wang Bai State Key Laboratory of Networking and Switching Technology Beijing University of Posts and Telecommunications Beijing 100876 P. R. China Department of Computer Science and Technology Tsinghua University Beijing 100084 P. R. China School of Computer Science Beijing University of Posts and Telecommunications Beijing 100876 P. R. China

The highly mobility of vehicles, intermittent communication between the vehicles and the requirements of real time applications are some of the main challenges of multi-hop message delivery in Vehicular Ad Hoc Networks （ VANETs ）. There are also additional challenges, especially when the destination for the message delivery is a moving vehicle. In this paper, we propose a novel multihop message delivery method, called the Coverage Area-based oPportunistic message forwarding algorithm （CAP）. The main idea of CAP is to cover the potential area of a moving target vehicle as much as possible with the reachable area of the required delivery messages, so that the message can be delivered successfully. Because the success ratio and overhead of the multi-hop message delivery are two important but incompatible parameters in CAP, two tunings are discussed in the algorithm in order to maintain the balance of the two parameters. The simulation results show that compared with other reference approaches, CAP provides an efficient message delivery with a higher success ratio and a shorter message deNNy.

关键词： coverage area opportunistic forwarding message delivery routing VANETs

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Efficient Security Multimedia System on Embedded Platform

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China Communications 2010年第4期7卷 120-125页

作者： wang Lifeng MENG Qinglei XIAO Chen MA Jian DU Yaogang wang wendong Beijing Electronic Science and Technology Institute Beijing 100070 China Institute of Network Technology Beijing University of Posts and Telecommunications Beijing 100876 China 706 Institute Second Academy of CASIC Beijing 100854 China School of Computer Science and Technology Bei Hang University Beijing 100083 China

Security video communication is a challenging task,especially for wireless video *** efficient security multimedia system on embedded platform is *** analyzing the hardware architecture and resource,the efficient DSP-based H.264/AVC coding is studied by efficient video coding techniques and system optimizing *** protect the confidentiality and integrity of media information,a novel security mechanism is presented,which includes user identify authentication and a perceptual video encryption algorithm based on exploiting the special feature of entropy coding in *** results show that the proposed hardware framework has high performance and achieves a better balance between security and *** proposed security mechanism can achieve high security and low complexity cost,and has a little effect on the compression ratio and transmission ***’s more,encoding and encryption at the same time,the performance of data process can meet real-time application.

关键词： H.264/AVC Encode Optimizing Encryption Identify Authentication

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Autonomic QoS Management Mechanism in Software Defined Network

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China Communications 2014年第7期11卷 13-23页

作者： wang wendong QI Qinglei GONG Xiangyan HU Yannan QUE Xirong State Key Laboratory of Network and Switching Technology Beijing University of Posts and TelecommunicationsBeijing 100876 P.R. China

With the increase of network complexity,the flexibility of network control and management becomes a nontrivial *** Software Defined Network(SDN) and Autonomic Network technologies are sophisticated technologies for the network control and *** two technologies could be combined together to construct a software defined self-managing solution for the future *** autonomic QoS management mechanism in Software Defined Network(AQSDN) is proposed in this *** AQSDN,the various QoS features can be configured autonomically in an OpenFlow switch through extending the OpenFlow and OF-Config *** on AQSDN,a novel packet context-aware QoS model(PCaQoS) is also introduced for improving the network *** takes packet context into account when packet is marked and managed into forwarding *** implementation of a video application's prototype which evaluates the self-configuration feature of the AQSDN and the enhancement ability of the PCaQoS is presented in order to validate this design.

关键词： software defined network autonomic management context aware quality of service (QoS)

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On Reliability-optimized Controller Placement for Software-Defined Networks

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China Communications 2014年第2期11卷 38-54页

作者： HU Yannan wang wendong GONG Xiangyang QUE Xirong CHENG Shiduan State Key Laboratory of Networking and Switching Technology Beijing University of Posts and Telecommunications Beijing 100876 PR.China

By decoupling control plane and data plane,Software-Defined Networking(SDN) approach simplifies network management and speeds up network *** benefits have led not only to prototypes,but also real SDN *** wide-area SDN deployments,multiple controllers are often required,and the placement of these controllers becomes a particularly important task in the SDN *** paper studies the problem of placing controllers in SDNs,so as to maximize the reliability of SDN control *** present a novel metric,called expected percentage of control path loss,to characterize the reliability of SDN control *** formulate the reliability-aware control placement problem,prove its NP-hardness,and examine several placement algorithms that can solve this *** extensive simulations using real topologies,we show how the number of controllers and their placement influence the reliability of SDN control ***,we also found that,through strategic controller placement,the reliability of SDN control networks can be significantly improved without introducing unacceptable switch-to-controller latencies.

关键词： Software-Defined Networking controller placement reliability networkoptimization

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