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Chinese Journal of Polymer Science 2015年第6期33卷 815-822页

作者： Xiu-bo Jiang qing-fei zhang 贺爱华 Key Laboratory of Rubber-Plastics Ministry of Education/Shandong Provincial Key Laboratory of Rubber-PlasticsSchool of Polymer Science and EngineeringQingdao University of Science and Technology

Abstract Two series of trans-1,4-poly（butadiene-co-isoprene） copolymers （TBIR） were prepared using the catalyst system TiCl4/MgCl2-Al（i-Bu）3 at different reaction temperatures. All dyad and triads sequence distributions, the number-average sequence length and the sequence concentration of the copolymers were calculated according to 13C-NMR spectra. The influences of temperature and initial molar ratio of butadiene to isoprene （Bd to Ip） on the distribution of the chain segments in the TBIR copolymers were discussed. The correlation of copolymer compositions and thermal properties were also evaluated, which facilitated the understanding of controlling the degree of crystallinity and the transition tempera^re by changing Bd content and temperature.

关键词： Trans-1,4- Isoprene Butadiene Copolymer Thermal properties.

Formation and Sintering Behavior of Nanocrystalline Fe-Ni Powder by Mechanical Alloying

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Journal of Iron and Steel Research International 2003年第3期10卷 75-78页

作者： CHEN wen-ge GU Chen-qing DING Bing-jun Xi'an University of Technology Xi'an Jiaotong University

The solid sintering behavior and mechanical properties of Fe-Ni powders prepared by mechanical alloying of elemental powders and hot pressing sintering in vacuum atmospheres were investigated. It was observed that the microstructure of the powder particles evolves in three stages. The alloy powder with average grain size of 20-30 nm was obtained. The sinter densification depends crucially on the particle rearrangement and the large amount of internal strain introduced during milling. The theoretical density of over 95 % was obtained after hot pressing sintering at 800 ℃ for 30 min with pressure of 50 MPa. No significant grain growth was observed during sintering. And also relatively high hardness was obtained.

关键词： mechanical alloying nanostructured material mechanical property hot pressing sintering

Eukaryotic initiation factor 5A2 and human digestive system neoplasms

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World Journal of Gastrointestinal Oncology 2019年第6期11卷 449-458页

作者： qing-Bin Meng Jing-Jing Peng Zi-Wei Qu Xiao-Min Zhu zhang wen Wei-Ming Kang Department of Gastrointestinal Surgery the First Hospital of Wuhan CityWuhan 430022Hubei ProvinceChina Department of Gastroenterology General Hospital of the Yangtze River ShippingWuhan 430015Hubei ProvinceChina 不详 Department of Hepato-Biliary-Pancreatic Surgery and Liver Transplantation the First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of General Surgery Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China

Eukaryotic initiation factor 5A2(eIF5A2),as one of the two isoforms in the family,is reported to be a novel oncogenic protein that is involved in multiple aspects of many types of human *** or gene amplification of EIF5A2 has been demonstrated in many *** evidence shows that eIF5A2 initiates tumor formation,enhances cancer cell growth,increases cancer cell metastasis,and promotes treatment resistance through multiple means,including inducing epithelial–mesenchymal transition,cytoskeletal rearrangement,angiogenesis,and metabolic *** of eIF5A2 in cancer correlates with poor survival,advanced disease stage,as well as metastasis,suggesting that eIF5A2 function is crucial for tumor development and maintenance but not for normal tissue *** these studies suggest that eIF5A2 is a useful biomarker in the prediction of cancer prognosis and serves as an anticancer molecular *** review focuses on the expression,subcellular localization,post-translational modifications,and regulatory networks of eIF5A2,as well as its biochemical functions and evolving clinical applications in cancer,especially in human digestive system neoplasms.

关键词： Eukaryotic translation initiation factor 5A2 Hypusine modification Acetylation modification Drug resistance Cancer therapeutics

玉米果穗相关性状QTL定位及重要候选基因分析

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作物学报 2024年第6期50卷 1435-1450页

作者：郑雪晴王兴荣张彦军龚佃明邱法展华中农业大学作物遗传改良全国重点实验室/湖北洪山实验室湖北武汉430070 甘肃省农业科学院作物研究所甘肃兰州730070

玉米果穗相关性状与产量直接相关,其遗传基础解析对于指导玉米遗传改良意义重大。本研究对3年6个环境下的168份高代回交重组自交系(AB-RILs)的穗长、穗行数和百粒重等8个性状进行表型鉴定,结合玉米10 K芯片产生的覆盖全基因组的11,407个... 详细信息

玉米果穗相关性状与产量直接相关,其遗传基础解析对于指导玉米遗传改良意义重大。本研究对3年6个环境下的168份高代回交重组自交系(AB-RILs)的穗长、穗行数和百粒重等8个性状进行表型鉴定,结合玉米10 K芯片产生的覆盖全基因组的11,407个SNP(Single Nucleotide Polymorphisms)标记对8个性状进行QTL定位。共鉴定到32个与8个果穗性状相关的QTL,其中包含5个环境一致性的QTL,3个多效性QTL。进一步利用507份关联群体的基因型与表型数据对主效QTL候选区间进行关联分析,鉴定到19个可能与果穗性状相关的重要候选基因,结合候选基因的进化分析和表达分析等,初步确定其中4个为关键候选基因。以上结果为玉米育种中果穗性状的遗传改良提供了重要的标记信息,同时也为果穗性状相关基因克隆提供指导。

关键词：玉米 AB-RIL群体果穗籽粒 QTL定位候选区间关联分析

Effect of austenitizing temperature on microstructure in 16Mn steel treated by cerium

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International Journal of Minerals,Metallurgy and Materials 2011年第6期18卷 652-658页

作者： Bin wen Bo Song Ning Pan qing-yun Hu Jing-hong Mao State Key Lab of Advanced Metallurgy University of Science and Technology Beijing Beijing 100083 China School of Metallurgical and Ecological Engineering University of Science and Technology Beijing Beijing 100083 China School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China

The change of inclusions and microstructure of 16Mn steel treated by Ce were observed,and the effect of austenitizing temperature on the microstructure was also *** results show that the inclusions are transformed from Si-Mn-Al composite oxide and MnS into AlCeO3,Ce2O2S,and MnS composite inclusions after being treated by *** of intragranular ferrites are formed in 16Mn steel containing～0.017wt% Ce.A large amount of intragranular acicular ferrites are formed after being austenitized for 20min at 1473 *** prior austenite grain size fit for the formation of intragranular acicular ferrites is about 120μm.

关键词： steel metallurgy inclusions ferrite austenite grain size

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市售肉类罐头产品现状

食品工业 2024年第7期45卷 103-109页

作者：董莉周娇李清曾庆陈秋月张崟成都大学肉类加工四川省重点实验室成都610106

随着现代社会经济的不断发展,肉制品罐头种类也随着国内家庭生活水平和肉制品罐头加工与生产技术水平的提高而持续增多。为明确市售肉类罐头产品现状,对近年来在我国市场上流通的肉类罐头产品进行调研,通过对市场上肉制品罐头的品牌、... 详细信息

随着现代社会经济的不断发展,肉制品罐头种类也随着国内家庭生活水平和肉制品罐头加工与生产技术水平的提高而持续增多。为明确市售肉类罐头产品现状,对近年来在我国市场上流通的肉类罐头产品进行调研,通过对市场上肉制品罐头的品牌、净含量、配料、保质期等信息进行调研,并对调研结果进行分类汇总和对比分析,结果发现:在罐头种类方面,以调味类肉罐头的数量及种类居多;在市场占用份额方面,梅林品牌的肉罐头的市场占有率较大;在食用方法方面,大多数肉类罐头以开罐即食方式居多;在净含量方面,畜肉罐头以100~200 g居多,禽肉罐头以300~400 g最多,水产罐头以100~200 g最多;在贮藏方法方面,肉类罐头以常温贮存居多;在保质期方面,大部分罐头的保质期为12~36个月,有少部分罐头保质期小于1个月。调研的开展对肉类罐头新产品开发中配方、品牌及净含量设计等具有参考价值。

关键词：肉罐头分类汇总对比分析

P2X7 Receptor in Alcoholic Steatohepatitis and Alcoholic Liver Fibrosis

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Journal of Clinical and Translational Hepatology 2022年第6期10卷 1205-1212页

作者： Guo-qing Xia Qian Fang Jun-Nan Cai Zi-Xuan Li Feng-Zhi zhang Xiong-wen Lv Institute for Liver Diseases of Anhui Medical University HefeiAnhuiChina The Key Laboratory of Anti-inflammatory and Immune Medicines Ministry of EducationHefeiAnhuiChina Inflammation and Immune-Mediated Diseases Laboratory of Anhui Province Anhui Institute of Innovative DrugsSchool of PharmacyAnhui Medical UniversityHefeiAnhuiChina Wannan Medical College Yijishan HospitalAffiliated Hospital 1WuhuAnhuiChina

Alcoholic liver disease is one of the most common chronic liver diseases in the *** is a liver disease caused by prolonged heavy drinking and its main clinical features are nausea,vomiting,enlargement of the liver,and *** studies suggest that Kupffer cell-mediated inflam-matory response is a core driver in the development of alco-holic steatohepatitis and alcoholic liver *** a danger signal,extracellular ATP activates the assembly of NLPR3 inflammasome by acting on purine P2X7 receptor,the ac-tivated NLRP3 inflammasome prompts ASC to cleave pro-cCaspase-1 into active caspase-1in *** caspase-1 promotes the conversion of pro-IL-1βto IL-1β,which fur-ther enhances the inflammatory ***,we briefly review the role of the P2X7R-NLRP3 inflammasome axis in the pathogenesis of alcoholic liver disease and the evolution of alcoholic steatohepatitis and alcoholic liver ***-ulation of the inflammasome axis of P2X7R-NLRP3 may be a new approach for the treatment of alcoholic liver disease.

关键词： ATP P2X7 receptor Kupffer cells NLRP3 inflammasome Alcoholic steatohepatitis Alcoholic liver fibrosis

Male fecundity prognosis and infertility diagnosis in the era of personalised medicine

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Asian Journal of Andrology 2010年第4期12卷 463-467页

作者： wen-Bing Zhu Xing-Yu Long Li-qing Fan Institute of Reproductive and Stem Cell Engineering Central South University Reproductive and Genetic Hospital of CITIC- Xiangya Central South University Changsha 410078 China

In daily clinical practice, we attempt to classify diseases according to patients＇ symptoms and reference values for certain tests. A minimal evaluation is performed following the diagnostic standard, and the patient is treated according to the diagnosis. In this ＇classification medicine＇ model, a patient＇s individual characteristics are more or less ignored.

关键词： Male fecundity prongosis infertility diagnosi era of personalised medicina

Synthesis and Crystal Structure of a New Three-dimensional Supramolecule of Copper(Ⅱ) Schiff Base Complex

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Chinese Journal of Structural Chemistry 2008年第2期27卷 187-190页

作者： LI Chun-Hong WANG Qiang XU Yan-qing HU Chang-wen Institute for Chemical Physics and Department of Chemistry Beijing Institute of Technology Beijing 100081 China State Key Laboratory of Explosion Science and Technology Beijing Institute of Technology BeOing 100081 China

A new three-dimensional supramolecule composed of copper-Schiff base complex, [Cu（naphdien）]Cl·H2O, where naphdien is Schiff base of 2-hydroxy-1-naphthaldehyde and diethylenetriamine, has been synthesized and determined by single-crystal X-ray diffraction. It belongs to the monoclinic system, space group P21/c, with a = 7.3490（15）, b = 7.0847（16）, c = 30.845（3）A, β= 95.33（3）°, V = 1599.0（5）A3, Z = 4, C15 H20ClCuN3O2, Mr = 373.33, De = 1.551 g/cm3, μ = 1.543 mm^-1, F（000） = 772, R = 0.0536 and wR = 0.0927 for 2788 unique reflections with 1659 observed ones （I 〉2σ（I））. In the crystal structure, mononuclear units [Cu（naphdien）]Cl·H2O are linked into a two-dimensional framework via strong hydrogen bonds, and extended into a three-dimensional supramolecular structure through π-π stacking interactions.

关键词： copper crystal structure Schiff base hydrogen bonds

NMR Study on Substituted Phenyl Furoisoxazolines

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Chinese Chemical Letters 2003年第3期14卷 298-299页

作者： Xiang zhang qing Hua CHEN 等 InstituteofMateriaMedica ChineseAcademyofMedicalSciences&PekingUnivonMedicalCollegeBeijing100050 DepartmentofChemistry BeijingNormalUniversityBeijing100875

The configurations of substituted phenyl furoisoxazolines were determined by study on their 1H-NMR and 1D NOESY. The characteristic chemical shifts of the g-lactone ring protons in 1H-NMR were also discussed.

关键词： H-NMR NOE configuration phenyl furoisoxazoline.