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Frontiers of Chemical Science and Engineering 2023年第8期17卷 1131-1139页

作者： wen-jie jin Yu Xin Xian-Wei Cheng jin-Ping Guan Guo-Qiang Chen Key Laboratory of Flame Retardancy Finishing of Textile Materials(CNTAC) College of Textile and Clothing EngineeringSoochow UniversitySuzhou 215123China

Riboflavin sodium phosphate has been confirmed as a promising biomass product derived from natural *** this paper,a novel method of dyeing and multifunctional modification of silk fabric by impregnation with riboflavin sodium phosphate was proposed,such that protein silk fabric can be endowed with bright yellow color and *** results of this paper confirmed that the pH and concentration of riboflavin sodium phosphate solution are critical factors for dyeing and multifunctional ***,the photochromic performance was one of the most distinctive features of the modified silk fabric,and the dyed silk fabric turned into fluorescent green from original yellow under 365 nm ultraviolet ***,the modified silk fabric exhibited good antibacterial properties with a high inhibition rate of 92%for Escherichia ***,the flame retardancy of silk fabric was significantly improved after *** damaged length of modified silk fabric with 40%owf riboflavin sodium phosphate was lower than 10.4 cm and passed the B1 *** revealed by the result of this paper,riboflavin sodium phosphate is sufficiently effective in serving as an eco-friendly multifunctional agent for strengthening the add-value of silk textiles.

关键词： biomass riboflavin sodium phosphate silk protein multifunctional modification flame retardant

Physiological property and yield of the sweet sorghum mutants induced by heavy ion irradiation

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Nuclear Science and Techniques 2016年第4期27卷 83-88页

作者： wen-Ting Gu wen-Jian Li Rui-Yuan Liu wen-jie jin Tao-Li-Wei Yang Xi-Cun Dong Institute of Modern Physics Chinese Academy of Sciences

Soil salinity can limit plant growth and productivity. The cultivation of tolerant varieties is convenient and cost-effective for making good use of the saline *** sweet sorghum plant has a high tolerance for saline alkaline soils. The KF1210-3 and KF1210-4 early-maturity mutants of sweet sorghum were obtained via carbon ion irradiation. The study assesses the productivity of three sweet sorghum cultivars(KF1210-3, KF1210-4, and KFJTCK) which were grown in intermediate(4.6 d S m^(-1)) and high(11.9 d S m^(-1)) soil salinity. The sweet sorghum grown in the soil salinity of 4.6 d S m^(-1)produced 50.00–57.30 %greater fresh weight than that in the soil salinity of11.9 d S m^(-1), while the difference was not as obvious among the dry biomass of the three sweet sorghum cultivars. Moreover, the Brix degree of the sweet sorghum grown in the soil salinity of 11.9 d S m^(-1)was greater than that grown in the soil salinity of 4.6 d S m^(-1). The heavy ion irradiation experiment is of great significance in screening plant mutants, improving environmental conditions, and assessing the productivity. This process, in turn, aids in the understanding of the effects of the biochemical and physiological mechanisms of salt stress.

关键词：早熟突变体甜高粱重离子生理特性辐照诱导土壤含盐量产量土壤盐分

Synergistic responses of NHX, AKT1, and SOS1 in the control of Na^+ homeostasis in sweet sorghum mutants induced by ^(12)C^(6+)-ion irradiation

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Nuclear Science and Techniques 2018年第1期29卷 32-38页

作者： wen-Ting Gu Li-Bin Zhou Rui-Yuan Liu wen-jie jin Ying Qu Xi-Cun Dong wen-Jian Li Institute of Modern Physics Chinese Academy of Sciences

Sweet sorghum mutants induced by^(12)C(6+)-ion irradiation were planted under different soil salinity conditions to investigate the mechanisms maintaining the transport and spatial distribution of Na^+. The functions of the synergistic responses of NHX, AKT1, and SOS1 related to Na^+ accumulation were investigated in control(KFJT-CK) sorghum and KF1210-3 and KF1210-4 mutants. The results indicated that the NHX, AKT1, and SOS1 proteins in sweet sorghum are mainly involved in the transport, exclusion, and spatial distribution of Na^+,respectively. In addition to physiological parameters, we also measured the expression levels of NHX, AKT1, and SOS1 genes. The experimental results indicated that 150 m M Na Cl induced marked increases in the transcripts of NHX and SOS1 after 8 and 12 h in the KF1210-3,KF1210-4, and KFJT-CK cultivars. In contrast, however, a decrease in AKT1 was observed. On the basis of our results, we propose a model in which cooperation amongNHX, AKT1, and SOS1 facilitates Na^+ homeostasis in sweet sorghum in response to an increase in salt concentration. Accordingly, study of the regulatory mechanisms in sweet sorghum generated by carbon ion irradiation is essential for the selection of salt-tolerant cultivars.

关键词： 12C6+-ion irradiation Sweet sorghum Salt stress NHX AKT1 SOS1

Changes in neurological and pathological outcomes in a modified rat spinal cord injury model with closed canal

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Neural Regeneration Research 2020年第4期15卷 697-704页

作者： Xin Sun Xing-Zhen Liu Jia Wang Hai-Rong Tao Tong Zhu wen-jie jin Kang-Ping Shen Shanghai Key Laboratory of Orthopedic Implants Department of Orthopedic SurgeryShanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Pathology Shanghai Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina

Most animal spinal cord injury models involve a laminectomy,such as the weight drop model or the transection ***,in clinical practice,many patients undergo spinal cord injury while maintaining a relatively complete spinal ***,open spinal cord injury models often do not simulate real injuries,and few previous studies have investigated whether having a closed spinal canal after a primary spinal cord injury may influence secondary ***,we aimed to assess the differences in neurological dysfunction and pathological changes between rat spinal cord injury models with closed and open spinal ***-Dawley rats were randomly divided into three *** the sham group,the tunnel was expanded only,without inserting a screw into the spinal *** the spinal cord injury with open canal group,a screw was inserted into the spinal canal to cause spinal cord injury for 5 minutes,and then the screw was pulled out,leaving a hole in the vertebral *** the spinal cord injury with closed canal group,after inserting a screw into the spinal canal for 5 minutes,the screw was pulled out by approximately 1.5 mm and the flat end of the screw remained in the hole in the vertebral plate so that the spinal canal remained closed;this group was the modified model,which used a screw both to compress the spinal cord and to seal the spinal *** 7 days post-operation,the Basso-Beattie-Bresnahan scale was used to measure changes in neurological ***-eosin staining was used to assess *** evaluate the degree of local secondary hypoxia,immunohistochemical staining and western blot assays were applied to detect the expression of hypoxia-inducible factor 1α(HIF-1α)and vascular endothelial growth factor(VEGF).Compared with the spinal cord injury with open canal group,in the closed canal group the Basso-Beattie-Bresnahan scores were lower,cell morphology was more irregular,the percentage of morphologically normal neurons was lower

关键词： Basso-Beattie-Bresnahan scores closed spinal canal HIF-1α hypoxia model nerve regeneration open spinal canal rat secondary injury spinal cord injury VEGF

Aldehyde dehydrogenase 2 overexpression inhibits neuronal apoptosis after spinal cord ischemia/reperfusion injury

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Neural Regeneration Research 2017年第7期12卷 1166-1171页

作者： Xing-zhen Liu Xin Sun Kang-ping Shen wen-jie jin Zhi-yi Fu Hai-rong Tao Zhi-xing Xu Shanghai Key Laboratory of Orthopedic Implants Department of Orthopedic surgery Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai China

Aldehyde dehydrogenase 2（ALDH2）is an important factor in inhibiting oxidative stress and has been shown to protect against renal ischemia/reperfusion ***,we hypothesized that ALDH_2 could reduce spinal cord ischemia/reperfusion *** cord ischemia/reperfusion injury was induced in rats using the modified Zivin＇s method of clamping the abdominal *** successful model establishment,the agonist group was administered a daily consumption of 2.5%*** 7 days post-surgery,the Basso,Beattie,and Bresnahan score significantly increased in the agonist group compared with the spinal cord ischemia/reperfusion injury ***_2expression also significantly increased and the number of apoptotic cells significantly decreased in the agonist group than in the spinal cord ischemia/reperfusion injury *** analysis revealed that ALDH_2 expression negatively correlated with the percentage of TUNEL-positive cells（r=-0.485,P〈0.01）.In summary,increased ALDH_2 expression protected the rat spinal cord against ischemia/reperfusion injury by inhibiting apoptosis.

关键词： nerve regeneration spinal cord ischemia/reperfusion injury aldehyde dehydrogenase 2 alcohol apoptosis oxidative stress terminaldeoxynucleotidyl transferase dUTP nick-end labeling neural regeneration

Association between SHBG(TAAAA)n and AR(CAG)n polymorphisms and PCOS risk: A meta-analysis

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World Journal of Meta-Analysis 2015年第1期3卷 72-81页

作者： jie-wen jin Shi-Lin Chen Zhan-Tao Deng Center for Translational Medicine and Jiangsu Key Laboratory of Molecular Medicine Medical School of Nanjing University

AIM: To systematically assess the association between sex hormone-binding globulin(SHBG)(TAAAA)n and androgen receptor(AR)(CAG)n polymorphisms and polycystic ovarian syndrome(PCOS) ***: We searched MEDLINE(PubM ed), EMBASE and Web of Science database from inception to May2014. To avoid missing any additional studies, we looked through all the references of relevant articles. Case-control studies concerning the(CAG)n variants in the AR gene or the(TAAAA)n polymorphism in the SHBG gene in PCOS patients were included. Five studies regarding the(TAAAA)n polymorphism in the SHBG gene and 14 studies regarding the(CAG)n polymorphism in the AR gene met our criteria. Odd ratio(OR) and weighted mean difference(WMD) were selected as the effect size measurements to evaluate the influence of the(TAAAA)n polymorphism and(CAG)n variants on PCOS risk. Begg's test was used for the evaluation of publication ***: With respect to the relationship between the(TAAAA)n polymorphism and PCOS risk, the statistical results showed that there was no significant difference between PCOS patients and controls in the alleles of TAAAA(S: OR = 0.91, 95%CI: 0.78-1.05; L: OR = 1.10, 95%CI: 0.95-1.27). Subgroup analyses of the combination of alleles indicated similar results(shortshort: OR = 0.87, 95%CI: 0.66-1.14; short-long: OR = 1.12, 95%CI: 0.86-1.46; long-long: OR = 1.03, 95%CI: 0.72-1.47). As for the relationship between the(CAG)n polymorphism and PCOS risk, we found no association between CAG repeat variants and PCOS risk(WDM = 0.03, 95%CI:-0.13-0.08). Subgroup analyses by race and diagnosis criteria indicated the same results(Asian: WMD =-0.03, 95%CI:-0.14-0.07; Caucasian: WMD =-0.02, 95%CI:-0.24-0.21; the criteria of Rotterdam: WMD = 0.01, 95%CI:-0.01-0.03). CONCLUSION: There is no association between(TAAAA)n polymorphism in SHBG gene,(CAG)n repeat variants in AR gene and PCOS.

关键词： Sex hormone-binding globulin TAAAA Androgen receptor CAG Polycystic ovarian syndrome

Protective effect and mechanisms of action of Mongolian medicine Sulongga-4 on pyloric ligation-induced gastroduodenal ulcer in rats

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World Journal of Gastroenterology 2021年第16期27卷 1770-1784页

作者： Shan Tong Huan Wang Li-Sha A Ta-Na Bai Ju-Hua Gong wen-jie jin Li-Li Dai Gen-Na Ba Sung-Bo Cho Ming-Hai Fu School of Mongolian Medicine Inner Mongolia University for NationalitiesTongliao 028000Inner Mongolia Autonomous RegionChina Mongolian Medicine Surgery Department Affiliated Hospital of Inner Mongolia University for NationalitiesTongliao 028000Inner Mongolia Autonomous RegionChina Traditional Mongolian Medicine Research Institute Inner Mongolia University for NationalitiesTongliao 028000Inner Mongolia Autonomous RegionChina

BACKGROUND Sulongga-4(SL-4)is a herbal formula used in traditional Mongolian medical clinics for the treatment of peptic ulcers and gastroenteritis,even though its pharmacological mechanism has not been well *** To evaluate the protective effect and identify the mechanisms of action of SL-4 on gastroduodenal ulcer induced by pyloric ligation(PL)in *** PL was performed to induce gastric and duodenal ulcers in rats,which were then treated with oral SL-4(1.3,2.6,or 3.9 g/kg per day)for 15 ***-induced gastroduodenal *** effects were characterized by pathological and histological evaluations and inflammatory indicators were analyzed by enzyme-linked immunosorbent *** analyses were conducted to identify gene expression profiles of gastroduodenal tissue in PL rats with or without SL-4 *** candidate target genes were selected and verified by quantitative reverse transcription polymerase chain reaction(qRT-PCR).RESULTS SL-4 decreased histopathological features in the PL-induced ulcerated ***-4 significantly (P < 0.05) decreased expression of tumor necrosis factor-α,interleukin (IL)-1β, IL-6, endotoxin, platelet-activating factor, and increasedprostaglandin E2 and epidermal growth factor in ulcer tissue. Microarray analysiswas used to identify a panel of candidate target genes for SL-4 acting on PLinducedulceration. Genes included some complement and coagulation cascadeand retinol metabolism pathways that are closely associated with inflammatoryresponses and gastric mucosal protective mechanisms. qRT-PCR showed thataltered expression of the selected genes, such as CYP2b2, UGT2b1, A2m, andMASP1 was consistent with the microarray ***-4 exerts protective effects against PL-induced gastroduodenal ulcers viareducing inflammatory cytokines and elevating expression of gastric acidinhibitory factors. Downregulation of CYP2b2 and UGT2b1 genes in retinolmetabolism and upregulation of A2m and MASP1 ge

关键词： Sulongga-4 Peptic ulcer Pyloric ligation Microarray analysis Inflammatory reaction Retinol metabolism

Membrane finite element method for simulating fluid flow in porous medium

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Water Science and Engineering 2009年第2期2卷 43-51页

作者： Mei-li ZHAN wen-jie ZHANG jin-chang SHENG Jian-hui LI Shu-yuan HE College of Water Conservancy and Hydropower Engineering Hohai University Nanjing 210098 P. R. China

A new membrane finite element method for modeling fluid flow in a porous medium is presented in order to quickly and accurately simulate the geo-membrane fabric used in civil engineering. It is based on discontinuous finite element theory, and can be easily coupled with the normal Galerkin finite element method. Based on the saturated seepage equation, the element coefficient matrix of the membrane element method is derived, and a geometric transform relation for the membrane element between a global coordinate system and a local coordinate system is obtained. A method for the determination of the fluid flux conductivity of the membrane element is presented. This method provides a basis for determining discontinuous parameters in discontinuous finite element theory. An anti-seepage problem regarding the foundation of a building is analyzed by coupling the membrane finite element method with the normal Galerkin finite element method. The analysis results demonstrate the utility and superiority of the membrane finite element method in fluid flow analysis of a porous medium.

关键词： membrane finite element normal Galerkin finite element method coupling fluidflow in porous medium

考虑自然对流的厚交换层液滴蒸发模型及其检验

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推进技术 2017年第3期38卷 620-629页

作者：王方杨少锋张学智姜文彬金捷北京航空航天大学能源与动力工程学院航空发动机数值仿真研究中心北京100191 先进航空发动机协同创新中心北京100191

两相模型对航空发动机燃烧室数值模拟的准确性至关重要,液体燃料的蒸发特性是两相模型的一个关键因素,为了得到准确合理的两相模型从而为燃烧室的设计提供依据,采用悬滴法实验研究了甲醇、煤油及航空煤油液滴在静止环境下的高温蒸发现象... 详细信息

两相模型对航空发动机燃烧室数值模拟的准确性至关重要,液体燃料的蒸发特性是两相模型的一个关键因素,为了得到准确合理的两相模型从而为燃烧室的设计提供依据,采用悬滴法实验研究了甲醇、煤油及航空煤油液滴在静止环境下的高温蒸发现象,并得到了液滴蒸发速率随环境温度的变化规律。比较实验数据与已有液滴蒸发模型计算结果,发现二者具有较大差距,分析认为已有模型应该考虑静止环境中自然对流对液滴蒸发的影响。在前人工作基础上,用考虑自然对流浮升力因素的厚交换层理论对静止环境下液滴的高温蒸发进行理论推导,得到新的蒸发模型。采用本文实验结果及文献液滴蒸发实验数据对新模型进行了检验。对于甲醇和煤油,在本文的实验工况下,新模型计算结果与实验结果具有较好的一致性,与实验的相对偏差不超过20%;对于煤油,新模型计算结果与文献实验结果的相对偏差不超过10%。

关键词：单液滴蒸发煤油甲醇蒸发率蒸发模型厚交换层理论

基于节点—场所模型的高铁站点地区规划评价——以长三角地区为例

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经济地理 2016年第10期36卷 18-25,38页

作者：宋文杰史煜瑾朱青张文新丁俊翔北京师范大学地理学与遥感科学学院中国北京100875 中国建筑设计院城镇规划设计研究院中国北京100044

随着我国高铁建设的快速发展,沿途城市将高铁站点作为城市发展新的增长极,对高铁站点地区的规划和建设给予了高度关注。基于贝托里尼的"节点—场所"橄榄球模型,通过测算长三角地区26个高铁站点的节点(交通)价值和场所(功能)价值,对高铁... 详细信息

随着我国高铁建设的快速发展,沿途城市将高铁站点作为城市发展新的增长极,对高铁站点地区的规划和建设给予了高度关注。基于贝托里尼的"节点—场所"橄榄球模型,通过测算长三角地区26个高铁站点的节点(交通)价值和场所(功能)价值,对高铁站点地区的规划进行实证评估。结果显示:杭州东站、南京南站、宜兴站等8个站点处于可持续发展状态,而大部分高铁站点偏离可持续发展状态。因此规划建设主体应兼顾高铁站点建设存在的潜力与风险,规划中采取有效的方式促进高铁站点地区可持续发展,以带动城市整体发展。

关键词：节点—场所模型高铁站点规划评价长三角地区