检索结果-南通市图书馆

Transition-metal free trifluoromethylimination of alkenes enabled by direct activation of N-unprotected ketimines

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第9期35卷 155-159页

作者： Boqiang Wang Yongzhuo xu Jiajia Wang Muyang Yang Guo-Jun Deng wen Shao Key Laboratory for Green Organic Synthesis and Application of Hunan Province Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of EducationCollege of ChemistryXiangtan UniversityXiangtan 411105China Department School of Chemistry and Chemical Engineering Henan Normal UniversityXinxiang 453007China

A highly site-selective intermolecular trifluoromethylimination of activated and unactivated olefins was reported under transition-metal-and photosensitizer-free *** newly developed strategy provides straightforward and efficient access to diverse value-added vicinal trifluoromethyl amines without resorting to the pre-functionalized *** experiments demonstrate that the approach proceeded through CF_(3)and iminyl two-radicals process,which were generated directly from commercially available benzophenone imine in a novel electron-donor mode via a SET process activated by the bifunctional hypervalent iodine *** synthetic potential of the protocols was further showcased via the condensation/amination sequential cascade,and transformations to accessβ-CF_(3)primary amines.

关键词： Transition-metal free Alkenes difunctionalization Amination Trifluoromethylation Single-electron transfer

A Model for Detecting Fake News by Integrating Domain-Specific Emotional and Semantic Features

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2024年第8期80卷 2161-2179页

作者： wen Jiang Mingshu Zhang xu’an Wang Wei Bin Xiong Zhang Kelan Ren Facheng Yan College of Cryptography Engineering Engineering University of People’s Armed PoliceXi’an710086China Key Laboratory of Network and Information Security Engineering University of People’s Armed PoliceXi’an710086China Key Laboratory of CTC&Information Engineering Engineering University of People’s Armed PoliceMinistry of EducationXi’an710086China

With the rapid spread of Internet information and the spread of fake news,the detection of fake news becomes more and more *** detection methods often rely on a single emotional or semantic feature to identify fake news,but these methods have limitations when dealing with news in specific *** order to solve the problem of weak feature correlation between data from different domains,a model for detecting fake news by integrating domain-specific emotional and semantic features is *** method makes full use of the attention mechanism,grasps the correlation between different features,and effectively improves the effect of feature *** algorithm first extracts the semantic features of news text through the Bi-LSTM(Bidirectional Long Short-Term Memory)layer to capture the contextual relevance of news ***-BiLSTM is then used to extract emotional features and predict the probability of positive and negative emotions in the *** then uses domain features as an enhancement feature and attention mechanism to fully capture more fine-grained emotional features associated with that ***,the fusion features are taken as the input of the fake news detection classifier,combined with the multi-task representation of information,and the MLP and Softmax functions are used for *** experimental results show that on the Chinese dataset Weibo21,the F1 value of this model is 0.958,4.9% higher than that of the sub-optimal model;on the English dataset FakeNewsNet,the F1 value of the detection result of this model is 0.845,1.8% higher than that of the sub-optimal model,which is advanced and feasible.

关键词： Fake news detection domain-related emotional features semantic features feature fusion

M^(6)A modification in cardiovascular disease:With a focus on programmed cell death

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genes & Diseases 2024年第5期11卷 272-284页

作者： wen Li Yao Liu Ruiyan xu Yuan Zong Lu He Jun Hu Guohua Li Institute of Cardiovascular Disease Key Laboratory for Arteriosclerology of Hunan ProvinceHunan International Scientific and Technological Cooperation Base of Arteriosclerotic DiseaseDepartment of PathophysiologyMOE Key Lab of Rare Pediatric DiseasesHengyang Medical SchoolUniversity of South ChinaHengyangHunan 421001China Department of Cardiovascular Medicine The Second Affiliated HospitalHengyang Medical SchoolUniversity of South ChinaHengyangHunan 421001China Department of Obstetrics and Gynecology The First Affiliated HospitalHengyang Medical SchoolUniversity of South ChinaHengyangHunan 421001China Department of Cardiovascular Surgery The Second Affiliated HospitalHengyang Medical SchoolUniversity of South ChinaHengyangHunan 421001China

N^(6)-methyladenosine(m^(6)A)methylation is one of the most predominant internal RNA modifications in eukaryotes and has become a hot spot in the field of epigenetics in recent *** diseases(CVDs)are a leading cause of death *** evidence demonstrates that RNA modifications,such as the m^(6)A modification,are associated with the development and progression of many diseases,including *** increasing body of studies has indicated that programmed cell death(PCD)plays a vital role in ***,the molecular mechanisms underlying m^(6)A modification and PCD in CVDs remain poorly ***,elaborating on the highly complex connections between the m^(6)A mechanisms and different PCD signaling pathways and clarifying the exact molecular mechanism of m^(6)A modification mediating PCD have significant meaning in developing new strategies for the prevention and therapy of *** is great potential for clinical application.

关键词： Apoptosis Autophagy Cardiovascular diseases Ferroptosis N^(6)-methyladenosine Programmed cell death Pyroptosis

Local resistance characteristics of elbows for supercritical pressure RP-3 flowing in serpentine micro-tubes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Propulsion and Power Research 2024年第2期13卷 245-256页

作者： Yanchen Fu Yinlong Liu Juan Wang Yu Wang Guoqiang xu Jie wen Research Institute of Aero-engine Beihang UniversityBeijing 100191China National Key Laboratory of Science and Technology on Aero-Engine Aero-thermodynamics Beihang UniversityBeijing 100191China Zhongfa Aviation Institute of Beihang University Hangzhou 310023China AECC Sichuan Gas Turbine Research Institute Chengdu 610500China AECC Hunan Aviation Powerplant Research Institute Zhuzhou 412002China School of Energy and Power Engineering Beihang UniversityBeijing 100191China

Based on the demands of compact heat exchangers and micro cooling channels applied for aviation thermal protection on aero-engines,the elbow localﬂow resistance charac-teristics for supercritical pressure aviation fuel RP-3ﬂowing in adiabatic horizontal serpentine tubes with the inner diameter of 1.8 mm and the massﬂux of 1179 kg/(m^(2)·s)were experimen-tally *** long-short-tube method was used to obtain the elbow pressure drop from the total serpentine tube pressure drop,and the effects of system pressures(P/Pc=1.72-2.58)and geometry parameters including bend numbers(n=5-11),bend diameters(D/d=16.7-27.8),and bend distances(L/d=20-60)on elbow pressure drops and local resistance co-efﬁcients are analyzed on the basis of the thermal physical property *** results show that both the increase in the elbow pressure drop and the decrease in the local resistance coef-ﬁcient with temperatures speed up at the near pseudo-critical temperature region of T>*** the growth of the elbow local pressure drop could be inhibited by the increase of system pressures,while the local resistance coefﬁcient is slightly affected by *** inﬂuence of bend diameters on the local resistance coefﬁcient is mild when D/d is larger than 22.2 in the premise of fully developedﬂow in straight ***,a piecewise empir-ical correlation considering the bend diameter and physical property ratio is developed to pre-dict the elbow pressure drop of the serpentine tube and optimize the layout of the cooling tube system on aero-engines.

关键词： Supercritical pressure Aviation fuel Local resistance coefﬁcient Elbow Serpentine tube Empirical correlation

A Gel-Based Solidification Technology for Large Fracture Plugging

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Fluid Dynamics & Materials Processing 2024年第3期20卷 563-578页

作者： Kunjian Wang Ruibin He Qianhua Liao Kun xu wen Wang Kan Chen Tianjin Branch of CNOOC(China)Co. Ltd.Tianjin300450China Jingzhou Jiahua Technology Co. Ltd.Jingzhou434001China

Fault fractures usually have large openings and considerable extension. Accordingly, cross-linked gel materials aregenerally considered more suitable plugging agents than water-based gels because the latter often undergo contaminationvia formation water, which prevents them from being effective over long times. Hence, in this study, aset of oil-based composite gels based on waste grease and epoxy resin has been developed. These materials havebeen observed to possess high compressive strength and resistance to the aforementioned contamination, therebyleading to notable increase in plugging success rate. The compressive strength, thickening time, and resistance toformation water pollution of these gels have been evaluated indoors. The results show that the compressivestrength of the gel can reach 11 MPa;additionally, the related gelation time can be controlled to be more than3 h, thereby providing a safe construction time;Invasion of formation water has a small effect on the gel strengthand does not shorten the thickening time. All considered performance indicators of the oil-based gel confirm itssuitability as a plugging agent for fault fractures.

关键词： Drilling loss fault fracture oil-based gel compressive strength gel plugging

EupDB:An integrative and comprehensive functional genomics data hub for Euphorbiaceae plants

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plant Communications 2024年第1期5卷 8-11页

作者： Jiazhi Liu Yan Li Jing Li wen Chen Bangzhen Pan Aizhong Liu Zeng-Fu xu Wei xu Changning Liu CAS Key Laboratory of Tropical Plant Resources and Sustainable Use Yunnan Key Laboratory of Crop Wild Relatives OmicsXishuangbanna Tropical Botanical GardenChinese Academy of SciencesKunming 650223China College of Life Sciences University of Chinese Academy of SciencesBeijing 100049China Key Laboratory of Vascular Biology and Translational Medicine Medical SchoolHunan University of Chinese MedicineChangsha 410208China Key Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China Ministry of EducationSouthwest Forestry UniversityKunming 650224China State Key Laboratory for Conservation and Utilization of Subtropical AgroBioresources College of ForestryGuangxi UniversityNanning 530003China Key Laboratory of National Forestry and Grassland Administration on Cultivation of Fast-Growing Timber in Central South China College of ForestryGuangxi UniversityNanning 530003China Germplasm Bank of Wild Species Yunnan Key Laboratory of Crop Wild Relatives OmicsKunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanChina

Dear Editor,Euphorbiaceae is one of the largest plant families,with nearly 218 genera and 6745 species,and includes many economically and medicinally important ***,cassava(Manihot esculenta)is well known as the"king of starches"and is the fourth most important food source in the tropics;rubber tree(Hevea brasiliensis)is a principal source of natural rubber for over 50000 industrial products worldwide;castor bean(Ricinus communis)is a globally important non-edible oilseed crop and the only commercial source of industrially valuable hydroxyl fatty acids.

关键词： esculenta) comprehensive rubber

Understanding the dehydrogenation properties of Mg(0001)/MgH_(2)(110)interface from first principles

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Materials Reports(Energy) 2024年第1期4卷 89-94页

作者： Jianchuan Wang Bo Han Zhiquan Zeng Shiyi wen Fen xu Yong Du State Key Laboratory of Powder Metallurgy Central South UniversityChangsha410083PR China Powder Metallurgy Research Institute Central South UniversityChangsha410083PR China Guangxi Key Laboratory of Information Materials Guilin University of Electronic TechnologyGuilin541004PR China

Magnesium hydride is one of the most promising solid-state hydrogen storage materials for on-board *** desorption from MgH_(2) is accompanied by the formation of the Mg/MgH_(2) interfaces,which may play a key role in the further dehydrogenation *** this work,first-principles calculations have been used to understand the dehydrogenation properties of the Mg(0001)/MgH_(2)(110) *** is found that the Mg(0001)/MgH_(2)(110) interface can weaken the Mg-H *** removal energies for hydrogen atoms in the interface zone are significantly lower compared to those of bulk MgH_(2).In terms of H mobility,hydrogen diffusion within the interface as well as into the Mg matrix is *** calculated energy barriers reveal that the migration of hydrogen atoms in the interface zone is easier than that in the bulk MgH_(2).Based on the hydrogen removal energies and diffusion barriers,we conclude that the formation of the Mg(0001)/MgH_(2)(110) interface facilitates the dehydrogenation process of magnesium hydride.

关键词： Magnesium hydrides First-principles calculation Hydrogen storage materials Interface Hydrogen desorption

Correlation analysis of interstitial maturity and prognosis of colorectal cancer:Meta-analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2024年第6期16卷 2816-2825页

作者： Zhen-Jun Liu xu-wen Zhang Qi-Qi Liu Shao-Zhao Wang Department of Gastrointestinal Surgery Feicheng People's HospitalFeicheng 271600Shandong ProvinceChina Department of Hepatobiliary Surgery Feicheng People's HospitalFeicheng 271600Shandong ProvinceChina Department of Gastrointestinal Surgery Peking University Shenzhen HospitalShenzhen 518036Guangdong ProvinceChina Department of Anorectal Word Central Hospital Affiliated Shandong First Medical UniversityJinan 250013Shandong ProvinceChina

BACKGROUND To investigate the relationship between interstitial maturity and prognosis of colorectal *** To examine the correlation between interstitial maturity and the prognosis of colorectal *** The paper database PubMed,EMBASE,Cochranelibrary,Springerlink,CNKI,and Wanfang database were searched until December 2023."tumor stroma maturity""desmoplastic stroma reaction""desmoplastic reaction""stroma reaction""degree of stroma reaction""stroma classification""stroma density""colorectal cancer""colon cancer""rectal cancer""prognosis"were searched for the search *** system assessors independently screened the literature quality according to the inclusion exclusion criteria,Quality evaluation and data extraction were performed for the included literatures,and meta-analysis was performed for randomized control trials included at using Review Manager 5.2 *** Finally,data of 9849 patients with colorectal cancer from 19 cosets in 15 literatures were included,including 4339 patients with mature type(control group),3048 patients with intermediate type(intermediate group)and 2456 patients with immature type(immature group).The results of meta-analysis showed:Relapse-free survival[hazard ratio(HR)=2.66,95%confidence interval(CI):2.30-3.08;P<0.00001],disease-free survival(HR=3.68,95%CI:2.33-5.81;P<0.00001)and overall survival(HR=1.70,95%CI:1.53-1.87;P<0.00001)were significantly lower than those in mature group(control group);relapse-free survival(HR=1.36,95%CI:1.17-1.59;P<0.0001)and disease-free survival rate(HR=1.85,95%CI:1.53-2.24;P<0.0001)was significantly lower than the mature group(control group).CONCLUSION There is the correlation between tumor interstitial maturity and survival prognosis of colorectal cancer,and different degrees of tumor interstitial maturity have a certain impact on the quality of life of colorectal cancer patients.

关键词： Colorectal tumor Survival prognosis Tumor interstitial maturity Systematic review Meta-analysis

Assessing the impact of interventions on the major Omicron BA.2 outbreak in spring 2022 in Shanghai

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Infectious Disease Modelling 2024年第2期9卷 519-526页

作者： Hengcong Liu Jun cai Jiaxin Zhou Xiangyanyu xu Marco Ajelli Hongjie Yu School of Public Health Fudan UniversityKey Laboratory of Public Health SafetyMinistry of EducationShanghaiChina Laboratory for Computational Epidemiology and Public Health Department of Epidemiology and BiostatisticsIndiana University School of Public HealthBloomingtonINUSA Shanghai Institute of Infectious Disease and Biosecurity School of Public HealthFudan UniversityShanghaiChina

Background Shanghai experienced a significant surge in Omicron BA.2 infections from March to June *** addition to the standard interventions in place at that time,additional interventions were implemented in response to the ***,the impact of these interventions on BA.2 transmission remains *** We systematically collected data on the daily number of newly reported infections during this wave and utilized a Bayesian approach to estimate the daily effective reproduction *** on public health responses were retrieved from the Oxford COVID-19 Government Response Tracker and served as a proxy for the interventions implemented during this *** a log-linear regression model,we assessed the impact of these interventions on the reproduction ***,we developed a mathematical model of BA.2 *** combining the estimated effect of the interventions from the regression model and the transmission model,we estimated the number of infections and deaths averted by the implemented *** We found a negative association(−0.0069,95%CI:0.0096 to−0.0045)between the level of interventions and the number of *** interventions did not ramp up during the outbreak,we estimated that the number of infections and deaths would have increased by 22.6%(95%CI:22.4–22.8%),leading to a total of 768,576(95%CI:768,021-769,107)infections and 722(95%CI:722–723)*** no interventions were deployed during the outbreak,we estimated that the number of infections and deaths would have increased by 46.0%(95%CI:45.8–46.2%),leading to a total of 915,099(95%CI:914,639-915,518)infections and 860(95%CI:860–861)*** Our findings suggest that the interventions adopted during the Omicron BA.2 outbreak in spring 2022 in Shanghai were effective in reducing SARS-CoV-2 transmission and disease *** findings emphasize the importance of non-pharmacological interventions in controlling quick surges of cases during

关键词： impact spring finding