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Chinese Chemical Letters 2024年第9期35卷 145-149页

作者： Qiuyun Li Yannan Zhu Yining Wang Gang Qi wen-Juan Hao Kelu Yan bo Jiang School of Chemistry and Chemical Engineering Yancheng Institute of TechnologyYancheng 224051China School of Chemistry&Materials Science Jiangsu Normal UniversityXuzhou 221116China Key Laboratory of Life-Organic Analysis of Shandong Province School of Chemistry and Chemical EngineeringQufu Normal UniversityQufu 273165China

Catalytic C–H activation-initiated annulation reactions have emerged as a versatile strategy for the efficient construction of diverse ring structural units and complex cyclic molecules in synthetic ***,we describe a new Rh(Ⅲ)-catalyzed C–H activation-initiated transdiannulation reaction of N,Ndimethyl enaminones with gem-difluorocyclopropenes in the presence of H_(2)O,enabling a facile and oxygen transfer access to ring-fluorinated tricyclicγ-lactones with a 6-5 ring-junction tetrasubstituted *** approach features bond-forming/annulation efficiency,good functional group tolerance and complete regioselectivity,which may include a complex process consisting of Rh(Ⅲ)-catalyzed C(sp2)–H activation,cyclic alkene insertion,defluorinated ring-opening of gem-difluorocyclopropane,intramolecular oxygen transfer,intramolecular cyclization and oxidative hydration.

关键词： C-H bond activation Enaminones Transannulation Oxygen transfer Regioselectivity

Substantial increase of heat-induced labor and economic loss in China under rapid economic and environmental temperature growth

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Advances in Climate Change Research 2024年第4期15卷 708-716页

作者： bo-wen CHU Jian-Feng LUO Ke-Xin WANG Zhen-Cheng XING Hai-Kun WANG Joint International Research Laboratory of Atmospheric and Earth System Sciences School of Atmospheric SciencesNanjing UniversityNanjing 210023China Collaborative Innovation Center of Climate Change Jiangsu ProvinceNanjing 210023China Frontiers Science Center for Critical Earth Material Cycling Nanjing UniversityNanjing 210023China Nanjin-Helski Insiute in Amosperc and Earth System Sciences Nanjing UniversityNanjing 210023China

Exposure to heat stress causes diminished work performance and leads to economic *** the last two decades,China has experienced both rapid economic development and environmental warming;however,the spatiotemporal variations of association between environmental heat and labor loss have been rarely investigated behind this double ***,we evaluated the variation in China's heat-induced labor productivity loss and related economic cost from 2001 to 2019 and investigated the effect of economic development and regional *** found that decline in labor productivity because of heat stress increased significantly(p<0.05 for heavy-intensity work),and the corresponding economic loss also exhibited a drastic increase by 6-to *** relative economic loss showed a slight but nonsignificant increase with an average value of 0.54%of the annual total *** the sub-regional and sectoral level,adverse effects were more prominent in the southeast region,and the secondary industry sectors,such as construction and manufacturing,contributed to larger proportions of economic *** transformation of industrial structure made economic sectors more vulnerable to heat exposure,and increasingly preventive effects of air-conditioning use were noted on economic damage due to heat-induced productivity decline(36.0%relative economic benefits in 2019 compared to 9.7%in 2001).Our findings could provide a deep insight into heat burden on occupational health and heat adaptation strategies regionally under climate change,especially in developing areas with higher temperature and humidity environment.

关键词： Heat stress Labor loss Wet bulb globe temperature China Economic impact

Characteristics of microscopic pore heterogeneity and development model of Wufeng‒Longmaxi Shales in the Pengshui area of south-east Chongqing

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Frontiers of Earth Science 2024年第1期18卷 188-203页

作者： Lu SUN Zhigang wen Guisong HE Peixian ZHANG Chenjun WU Liwen ZHANG Yingyang XI bo LI College of Resources and Environment Yangtze UniversityWuhan 430100China Research Institute of Exploration and Development Sinopec East China CompanyNanjing 210011China

Normal-pressure shale gas reservoirs are widely distributed in south-eastern Chongqing and show good potential for resource *** paper reports the organic matter(OM),physical,and pore characteristics,mineral composition,and gas content of representative shale samples from the Upper Ordovician Wufeng Formation and Member 1 of the Lower Silurian Longmaxi Formation(Long 1 Member).Microscopic pores within different shale layers of the Long 1 Member were classified,quantitatively evaluated,and their development mechanisms were systematically *** found that OM characteristics,mineral composition,and pore type were the main factors affecting the enrichment and preservation of shale *** characteristics of the Long 1 Member are mainly controlled by changes in the sedimentary *** are evident differences in total organic carbon content and mineral composition vertically,leading to a variable distribution of pores across different *** matter abundance controls the degree of OM pore development,while clay minerals abundance control the development of clay mineral-related *** organic carbon content generally controls the porosity of the Long 1 Member,but clay minerals also play a role in OM-poor *** connectivity and permeability are influenced by the development of pores associated with brittle *** propose a microscopic pore development model for the different *** geochemical data and this pore development model,layers 1‒4 are considered to be excellent shale gas preservation and enrichment *** preservation conditions in layers 5‒7 result in high levels of shale gas *** 8‒9 possess a better sealing condition compared with layers 5‒7 and are conducive to the enrichment and preservation of shale gas,and can thus be used as future potential target *** research provides a theoretical basis for exploring and evaluating shale gas potential in the studied region or other co

关键词： shale gas pore characteristics Longmaxi Formation reservoir model

Correlation of personality with individual reproductive success in shrub-nesting birds depends on their life history style

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Avian Research 2024年第1期15卷 42-49页

作者： Jianchuan Li wen Zhang Ningning Sun Yujie Wang Lifang Gao Ran Feng Liqing Fan bo Du Tibet Museum of Natural Science Lhasa850011China School of Life Sciences Lanzhou UniversityLanzhou730000China Institute of Plateau Ecology Tibet Agricultural and Animal Husbandry UniversityLinzhi860000China

Two questions in the research of animal personality—whether there is a correlation between a personality trait and individual reproductive success,and what is the genetic basis underlying a personality trait—remain *** addressed these two questions in three shrub-nesting birds,the Azure-winged Magpie(Cyanopica cyanus,AM),White-collared Blackbird(Turdus albocinctus,WB),and Brown-cheeked Laughingthrush(Trochalopteron henrici,BL).The personality type of an individual was first identified according to its response to a territorial ***,we compared the fleeing distance,breeding parameters,and differential expressed genes(DEGs) in the brain transcriptome between bold and shy *** the three species,bold breeders exhibited more aggressiveness towards an intruder of their territory than did shy *** reproductive success of bold breeders was significantly higher than that of shy breeders in AM but not in WB and *** three species shared one DEG,crabp1,which was up-regulated in bold relative to in shy *** regulating the expression of corticotropin-releasing hormone,higher crabp1 gene expression can decrease cellular response to retinoic ***,bold individuals are insensitive to external stresses and able to exhibit more aggressiveness to intruders than their shier *** is beneficial to bold individuals in AM but not in WB and BL because the former could evoke neighbors to make the same response of defending against intruders but the latter could *** a personality trait may have the same genetic basis across species,its correlation with reproductive success depends largely on the life history style of a species.

关键词： boldness Life history style Personality Reproductive success Transcriptome analysis

Transcriptomic analysis identifies the neuropeptide cortistatin (CORT) as an inhibitor of temozolomide (TMZ) resistance by suppressing the NF-kB-MGMT signaling axis in human glioma

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Genes & Diseases 2024年第3期11卷 385-399页

作者： Zongze He bo Peng Qi Wang Jie Tian Ping Liu Jie Feng Yiwei liao Longyi Chen Ping Jia Jian Tang Department of Neurosurgery Sichuan Provincial People's HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuan 610072China Department of Rehabilitation Medicine Sichuan Provincial People's HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuan 610072China Department of Neurosurgery Xiangya HospitalCentral South UniversityChangshaHunan 410008China

Glioma is a common tumor originating in the brain that has a high mortality ***(TMZ)is the first-line treatment for high-grade ***,a large pro-portion of gliomas are resistant to TMZ,posing a great challenge to their *** the study,the specific functions and mechanism(s)by which cortistatin(CORT)regulates TMZ resis-tance and glioma progression were *** decreased expression of CoRT was detected in glioma tissues,and highly expressed CORT was associated with a better survival rate in pa-tients with *** overexpression notably decreased the capacity of glioma cells to pro-liferate and migrate in vitro and to form tumors in *** overexpression also markedly suppressed the viability and enhanced the apoptosis of TMZ-resistant U251 cells by regulating MGMT,p21,and Puma ***,CORT overexpression reduced the resistance of gliomas to TMZ in *** expression Was negatively correlated with MGMT expression in both glioma tissues and cells,and it was found that CORT inhibited NF-kB pathway activation in glioma cells,thereby inhibiting MGMT *** conclusion,CORT regulates glioma cell growth,migration,apoptosis,and TMZ resistance by weakening the activity of NF-kB/p65 and thereby regulating MGMT *** CORT/NF-kB/MGMT axis might be regarded as a molecular mechanism contributing to the resistance of glioma to *** data also suggest that CORT regulates the viability and metastatic potential of glioma cells,independent of its effects on TMZ resistance,providing evidence of novel therapeutic targets for glioma that should be evaluated infurther studies.

关键词： Cortistatin Glioma MGMT NF-kB pathway Temozolomide

A new infrageneric classification of Gastrochilus(Orchidaceae:Epidendroideae)based on molecular and morphological data

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Plant Diversity 2024年第4期46卷 435-447页

作者： Jun-Yi Zhang Yue-Hong Cheng Min liao Yu Feng Sen-Long Jin Ting-Mei He Hai He bo Xu China-Croatia“Belt and Road”Joint Laboratory on Biodiversity and Ecosystem Services CAS Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization&Ecological Restoration and Biodiversity Conservation Key Laboratory of Sichuan ProvinceChengdu Institute of BiologyChinese Academy of SciencesP.O.Box 416Chengdu 610041SichuanChina College of Life Sciences Chongqing Normal UniversityChongqing 401331China Wolong National Natural Reserve Administration Bureau Wenchuan 623006SichuanChina University of Chinese Academy of Sciences Beijing 100049China

Gastrochilus is an orchid genus containing 73 species of mainly epiphytic on trees or rocks in mountain forests of tropical and subtropical *** phylogenetic analyses and morphological assessments have failed to produce a well-resolved phylogeny at the infrageneric *** the present study,a new infrageneric classification of Gastrochilus is proposed based on thoroughly morphological and phylogenetic analyses based on 52 *** phylogenetic analysis divided the genus into six sections including three new sections,***,*** and *** also reinstate *** to the specific ***,two new species,*** Jun ***,***&Yue *** and *** Jun ***,***&Yue ***,are described and illustrated.A key to six sections of the genus is presented.

关键词： Gastrochilus Phylogeny Character evolution Taxonomy New species

Genetic dissection and validation of a major QTL for grain weight on chromosome 3B in bread wheat(Triticum aestivum L.)

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Journal of Integrative Agriculture 2024年第1期23卷 77-92页

作者： Simin liao Zhibin Xu Xiaoli Fan Qiang Zhou Xiaofeng Liu Cheng Jiang Liangen Chen Dian Lin bo Feng Tao Wang Chengdu Institute of Biology Chinese Academy of SciencesChengdu 610041China University of Chinese Academy of Sciences Beijing 100049China The Innovative Academy of Seed Design Chinese Academy of SciencesBeijing 100101China

Grain weight is one of the key components of wheat(Triticum aestivum L.)*** manipulation of grain weight is an efficient approach for improving yield potential in breeding programs.A recombinant inbred line(RIL)population derived from a cross between W7268 and Chuanyu 12(CY12)was employed to detect quantitative trait loci(QTLs)for thousand-grain weight(TGW),grain length(GL),grain width(GW),and the ratio of grain length to width(GLW)in six *** major QTLs,***-2D,***-2D,***-3B,***-4B.1,***-2D.1,***-2D.1 and ***-3B.1,were consistently identified in at least four environments and the best linear unbiased estimation(BLUE)datasets,and they explained 2.61 to 34.85%of the phenotypic *** interactions were detected between the two major TGW QTLs and three major GW *** addition,***-3B.1 and ***-3B were co-located,and the improved TGW at this locus was contributed by *** other loci,***-3B.1/***-3B had no effect on grain number per spike(GNS).They were further validated in advanced lines using Kompetitive Allele Specific PCR(KASP)markers,and a comparison analysis indicated that ***-3B.1/***-3B is likely a novel *** haplotypes were identified in the region of this QTL and their distribution frequencies varied between the landraces and *** to gene annotation,spatial expression patterns,ortholog analysis and sequence variation,the candidate gene of ***-3B.1/***-3B was ***,the major QTLs and KASP markers reported here provide valuable information for elucidating the genetic architecture of grain weight and for molecular marker-assisted breeding in grain yield improvement.

关键词： thousand-grain weight QTL mapping haplotype analysis candidate gene

Effect of male HBV infection on the outcomes of IVF/ICSI cycles:a retrospective cohort study based on propensity score matching

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Asian Journal of Andrology 2024年第4期26卷 415-420页

作者： Su-Qin Zhu Xiu-Hua liao wen-wen Jiang Yan Sun Hui-Ling Xu Xiao-Jing Chen Bei-Hong Zheng Fujian Provincial Reproductive Medicine Center Fujian Maternity and Child Health HospitalCollege of Clinical Medicine for Obstetrics and Gynecology and PediatricsFujian Medical UniversityFuzhou 350001China Fujian Key Laboratory of Prenatal Diagnosis and Birth Defect Fuzhou 350001China Fujian Maternal-Fetal Clinical Medicine Research Center Fuzhou 350001China.

This study aimed to investigate the effects of male hepatitis B virus(HBV)infection on male fertility,embryonic development,and in vitro fertilization/intracytoplasmic sperm injection(IVF/ICSI)*** performed a retrospective cohort study that included 3965 infertile couples who received fresh embryo transfer cycles for the first time at the Fujian Maternity and Child Health Hospital(Fuzhou,China)from January 2018 to January *** couples were categorized based on their HBV infection status into the HBV group(HBV-positive men and HBV-negative women)and the control group(HBV-negative couples).A 1:1 propensity score matching was performed with relatively balanced *** characteristics,semen parameters,laboratory outcomes,clinical outcomes,and obstetric and neonatal outcomes were compared between *** propensity score matching,821 couples were included in each *** groups had similar semen parameters and obstetric and neonatal *** HBV group showed a significantly lower live birth rate than the control group(Pbortion rate than the control group(Pboth P<0.05).In conclusion,in couples who undergo IVF/ICSI,male HBV infection reduces the live birth rate and increases the risk of ***,the incidence of low birth weight in women with IVF/ICSI does not increase with male HBV infection.

关键词： hepatitis B virus in vitro fertilization intracytoplasmic sperm injection live birth rate propensity score matching

Robotic versus laparoscopic surgery for sporadic benign insulinoma:Short-and long-term outcomes

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Hepatobiliary & Pancreatic Diseases International 2024年第4期23卷 399-405页

作者： Zhu-Zeng Yin Yuan-Xing Gao Zhi-Ming Zhao Ming-Gen Hu wen-bo Tang Rong Liu Faculty of Hepato-Pancreato-Biliary Surgery The First Medical CenterChinese PLA General HospitalBeijing 100853China Institute of Hepatobiliary Surgery of Chinese PLA Beijing 100853China Key Laboratory of Digital Hepatobiliary Surgery of Chinese PLA Beijing 100853China

Background:Minimally invasive surgery is the optimal treatment for *** present study aimed to compare short-and long-term outcomes of laparoscopic and robotic surgery for sporadic benign ***:A retrospective analysis of patients who underwent laparoscopic or robotic surgery for insulinoma at our center between September 2007 and December 2019 was *** demographic,perioperative and postoperative follow-up results were compared between the laparoscopic and robotic ***:A total of 85 patients were enrolled,including 36 with laparoscopic approach and 49 with robotic *** was the preferred surgical ***-nine patients(69.4%)underwent enucleation;among them,26 and 33 patients underwent laparoscopic and robotic surgery,*** enucleation had a lower conversion rate to laparotomy(0 vs.19.2%,P=0.013),shorter operative time(102.0 vs.145.5 min,P=0.008)and shorter postoperative hospital stay(6.0 vs.8.5 d,P=0.002)than laparoscopic *** were no differences between the groups in terms of intraoperative blood loss,the rates of postoperative pancreatic fistula and *** a median follow-up of 65 months,two patients in the laparoscopic group developed a functional recurrence and none of the patients in the robotic group had a ***:Robotic enucleation can reduce the conversion rate to laparotomy and shorten operative time,which might lead to a reduction in postoperative hospital stay.

关键词： Robotic surgical procedures Laparoscopy Insulinoma Enucleation Pancreatectomy

Cationic engineered nanodiamonds for efficient antibacterial surface with strong wear resistance

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Nano Research 2024年第3期17卷 939-948页

作者： Fu-Kui Li wen-bo Zhao Yong Wang wen-Tao Huang Ya-Lun Ku Hang Liu Rui Guo Hui-Hui Yu Kai-Kai Liu Chong-Xin Shan Henan Key Laboratory of Diamond Optoelectronic Materials and Devices Key Laboratory of Materials PhysicsMinistry of Educationand School of Physics&MicroelectronicsZhengzhou UniversityZhengzhou 450052China

The spread of diseases caused by bacterial adhesion and immobilization in public places constitutes a serious threat to public *** of bacteria spread by the construction of an antibacterial surface takes precedence over post-infection ***,we demonstrate an effective antibacterial surface with strong wear resistance by constructing cationic engineered nanodiamonds(C-NDs).The C-NDs with positive surface potentials interact effectively with bacteria through electrostatic interactions,where the C-NDs act on the phospholipid bilayer and lead to bacterial membrane collapse and rupture through hydrogen bonding and residual surface oxygen-containing reactive *** this case,bactericidal rate of 99.99%and bacterial biofilm inhibition rate of more than 80%can be achieved with the C-NDs concentration of 1 mg/*** addition,the C-NDs show outstanding antibacterial stability,retaining over 87%of the antibacterial effect after stimulation by adverse environments of heat,acid,and external ***,an antibacterial surface with high wear resistance obtained by integrating C-NDs with commercial plastics has been *** antibacterial surface with a mass fraction of 1 wt.%C-NDs improved abrasion resistance by 3981 times,with 99%killing of adherent *** work provides an effective strategy for highly efficient antibacterial wear-resistant surface,showing great practical applications in public health environments.

关键词： antibacterial surface cationic engineered nanodiamonds wear-resistant