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Major complications after radiofrequency ablation for liver tumors:Analysis of 255 patients

World Journal of Gastroenterology 2009年第21期15卷 2651-2656页

作者： wen-tao kong wei-wei zhang yu-dong qiu tie zhou jun-lan qiu wei zhang yi-tao ding Department of Hepatobiliary Surgery Drum Tower Hospital Medical College of Nanjing University Nanjing 210008 Jiangsu Province China

AIM:To investigate the major complications after radiofrequency ablation(RFA) for the treatment of liver tumors and analyze possible risk factors that precipitate these ***:From March 2001 to April 2008,255 patients with liver tumors(205 male,50 female;age range,18-89 years;mean age,56.0 years) who received RFA were enrolled in this *** these patients,212 had hepatocellular carcinoma,39 had metastatic liver tumors and four had cholangiocellular *** hundred and forty eight patients had a single tumor,and 107 had multiple *** diameter of the tumors ranged 1.3-20 cm(mean,5.1 cm).All patients were treated with a cooled-tip perfusion electrode attached to a radiofrequency generator(Radionics,Burlington,MA,USA).RFA was performed via the percutaneous approach(n = 257),laparoscopy(n = 7),or open surgical treatment(n = 86).The major complications related to RFA were *** resultant data were analyzed to determine risk factors associated these ***:Among the 255 patients,425 liver tumors were treated and 350 RFA sessions were ***-seven(10%) major complications were observed which included 13 cases of liver failure,10 cases of hydrothorax requiring drainage,three casesof tumor seeding,one case of upper gastrointestinal bleeding,one case ofintrahepatic abscess,one case of bile duct injury,one case of cardiac arrest,and five cases of *** patients had more than two *** failure was the most severe complication and was associated with the highest *** patients died due to worsening liver ***-Pugh classification(P = 0.001) and choice of approach(P = 0.045) were related to post-treatment liver failure,whereas patient age,tumor size and number were not significant factors precipitating this ***:RFA can be accepted as a relatively safe procedure for the treatment of liver ***,attention should be paid to possible com

关键词： Complication Hepatocellular carcinoma Metastatic liver tumor Radiofrequency ablation Liverfailure

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Coevolutionary insights between promoters and transcription factors in the plant and animal kingdoms

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Zoological Research 2022年第5期43卷 805-812页

作者： Jing-Song zhang Hai-Quan Wang Jie Xia Kun Sha Shu-tao He Hao Dai Xiao-Hu Hao yi-wei zhou qiu Wang Ke-Ke ding zhang-Lei Ju wen Wang Luo-Nan Chen Key Laboratory of Systems Biology Shanghai Institute of Biochemistry and Cell BiologyCenter for Excellence in Molecular Cell ScienceChinese Academy of SciencesShanghai 200031China Department of General Surgery Shanghai General Hospital of Shanghai Jiao Tong University School of MedicineShanghai 200080China College of Information Engineering Zhejiang University of TechnologyHangzhouZhejiang 310023China Naval Healthcare Information Center Faculty of Military Health ServicesNaval Medical UniversityShanghai 200433China Bioinformatics Core of Excellence Department GenScript Biotech CorporationNanjingJiangsu 211110China Waigaoqiao Free Trade Zone Wuxi BiologicsShanghai 200131China Department of Cardiology Tongji HospitalTongji University School of MedicineShanghai 200065China School of Ecology and Environment Northwestern Polytechnical UniversityXi’anShaanxi 710072China State Key Laboratory of Genetic Resources and Evolution Kunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650223China Key Laboratory of Systems Health Science of Zhejiang Province School of Life ScienceHangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesChinese Academy of SciencesHangzhouZhejiang 310024China Guangdong Institute of Intelligence Science and Technology ZhuhaiGuangdong 519031China

The divergence and continuous evolution of plants and animals contribute to ecological *** and transcription factors(TFs) are key determinants of gene regulation and transcription ***,theevolutionary trajectories and relationships of promoters and TFs are still poorly understood. Here, we conducted extensive analysis of large-scale multi-omics sequences in 420 animal species and 223 plant species spanning nearly a billion years of evolutionary history. Results showed that promoter GC-contentandTFisoelectricpoints,as features/signatures that accompany long biological evolution, exhibited increasing growth in animal cells but a decreasing trend in plant cells. Furthermore, the evolutionary trajectories of promoter and TF signatures in the animal kingdom provided further evidence that Mammalia as well as Aves evolved directly from the ancestor Reptilia. The strong correlation between promoter and TF signatures indicates that promoters and TFs formed antagonistic coevolution in the animal kingdom, but mutualistic coevolution in the plant kingdom. The distinct coevolutionary patterns potentially drive the plant-animal divergence, divergent evolution and ecological diversity.

关键词： Molecularevolution Coevolution Promoter Transcription factor Plant-animal divergence

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Development of a MWDC prototype of the CSR external-target experiment

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Nuclear Science and Techniques 2024年第10期35卷 121-134页

作者： zhou-Bo He Zhi Qin Peng Ma He-Run Yang Xiang-Lun wei Chen-Gui Lu Xiang-Jie wen Xiu-Ling zhang tao Chen Zhi-Jie Li yuan-Sheng Yang Mei-Qiang Zhan Can-wen Liu Meng Li Tian-Li qiu yi-wei Gong Xin-Jie Huang Xiao-Hao yin Zhi-Xuan He jun-wei zhang Hai-Chuan Zou Sheng-wei Fu dong Guo jun-wei Yan Zhe Cao Zhi Deng Jie kong Zhi-Gang Xiao Rong-Jiang Hu Li-Min Duan Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China Department of Physics Tsinghua UniversityBeijing 100084China University of Science and Technology of China Hefei 230026China Key Laboratory of Radiation Physics and Technology of the Ministry of Education Institute of Nuclear Science and TechnologySichuan UniversityChengdu 610064China School of Nuclear Science and Technology Lanzhou UniversityLanzhou 730000China North China University of Water Resources and Electric Power Zhengzhou 450000China

The cooling storage ring(CSR)external-target experiment(CEE)is a spectrometer used in construction to study the properties of nuclear matter in high-baryon density regions at the Heavy-Ion Research Facility in lanzhou(HIRFL).This study presents the design,simulation,manufacturing,and testing of a half-size prototype of a multi-wire drift chamber(MWDC)for the ***,the performance of the MWDC connected to homemade electronics was *** results demonstrated that an energy resolution of 18.5% for 5.9-keV X-rays and a position resolution of 194μm for protons can be achieved by the current *** the size of the largest MWDC reached 176 cm×314 cm,a set of 98 cm×98 cm prototypes was built using the new *** positioning accuracy of the anode wires in this prototype is better than 20μ*** optimization,using commercially available electronics,the prototype can achieved an energy resolution of 19.7%for a^(55)Fe X-ray *** CEE-MWDC detector and electronics were simultaneously *** energy resolution of 22%was achieved for the^(55)Fe source;the track residuals were approximately 330μm for the cosmic *** results demonstrate that the current design and techniques meet the requirements of the CEE-MWDC array.

关键词： CEE MWDC Garfield++ ^(55)Fe source Position resolution

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Safety and efficacy of meplazumab in healthy volunteers and COVID-19 patients: a randomized phase 1 and an exploratory phase 2 trial

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Signal Transduction and Targeted Therapy 2021年第6期6卷 1845-1855页

作者： Huijie Bian Zhao-Hui Zheng ding wei Aidong wen Zheng zhang Jian-Qi Lian wen-Zhen Kang Chun-qiu Hao Jing Wang Rong-Hua Xie Ke dong Jie-Lai Xia Jin-Lin Miao wen Kang Guoquan Li Di zhang Mingru zhang Xiu-Xuan Sun Likun ding Kui zhang junfeng Jia Jin ding Zhiqin Li Yanyan Jia Lin-Na Liu Zhe zhang Zhao-wei Gao Hong Du Na Yao Qing Wang Ke Wang Jie-Jie Geng Bin Wang Ting Guo Ruo Chen yu-Meng Zhu Li-Juan Wang Qian He Rui-Rui Yao ying Shi Xiang-Min Yang Jian-Sheng zhou yi-Nan Ma Ya-tao Wang Xue Liang Fei Huo Zhe Wang Yang zhang Xu Yang Ye zhang Lu-Hua Gao Ling Wang Xiao-Chun Chen Hao Tang Shuang-Shuang Liu Qing-yi Wang Zhi-Nan Chen Ping Zhu National Translational Science Center for Molecular Medicine and Department of Cell Biology Fourth Military Medical UniversityXi'anChina Department of Clinical Immunology Xijing HospitalFourth Military Medical UniversityXi'anChina Department of Pharmacy Xijing HospitalFourth Military Medical UniversityXi'anChina Center for Infectious Diseases Tangdu HospitalFourth Military Medical UniversityXi'anChina Department of Nuclear Medicine Xijing HospitalFourth Military Medical UniversityXi'anChina department of Clinical Diagnosis Tangdu HospitalFourth Military Medical UniversityXKanChina College of Military Preventive Medicine Fourth Military Medical UniversityXi'anChina Department of Pharmaceutics Tangdu HospitalFourth Military Medical UniversityXi'anChina Department of Pathology Fourth Military Medical UniversityXi'anChina Jiangsu Pacific Meinuoke Biopharmaceutical Co.Ltd ChangzhouChina Department of Foreign languages Fourth Military Medical UniversityXi'anChina

Recent evidence suggests that CD147 serves as a novel receptor for severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)*** CD147 via anti-CD147 antibody could suppress the in vitro SARS-CoV-2 *** is a humanized anti-CD147 IgG_(2) monoclonal antibody,which may effectively prevent SARS-CoV-2 infection in coronavirus disease 2019(COVID-19)***,we conducted a randomized,double-blinded,placebo-controlled phase 1 trial to evaluate the safety,tolerability,and pharmacokinetics of meplazumab in healthy subjects,and an open-labeled,concurrent controlled add-on exploratory phase 2 study to determine the efficacy in COVID-19 *** phase 1 study,59 subjects were enrolled and assigned to eight cohorts,and no serious treatment-emergent adverse event(TEAE)or TEAE grade≥3 was *** serum and peripheral blood Cmax and area under the curve showed non-linear pharmacokinetic *** obvious relation between the incidence or titer of positive anti-drug antibody and dosage was observed in each *** biodistribution study indicated that meplazumab reached lung tissue and maintained>14 days stable with the lung tissue/cardiac blood-pool ratio ranging from 0.41 to *** the exploratory phase 2 study,17 COVID-19 patients were enrolled,and 11 hospitalized patients were involved as concurrent *** meplazumab treatment significantly improved the discharged(P=0.005)and case severity(P=0.021),and reduced the time to virus negative(P=0.045)in comparison to the control *** results show a sound safety and tolerance of meplazumab in healthy volunteers and suggest that meplazumab could accelerate the recovery of patients from COVID-19 pneumonia with a favorable safety profile.

关键词： patients dosage phase

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Efficacy and safety of sirolimus early conversion protocol in liver transplant patients with hepatocellular carcinoma:A single-arm, multicenter, prospective study

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Hepatobiliary & Pancreatic Diseases International 2022年第2期21卷 106-112页

作者： Ren-yi Su Sun-Bin Ling Qiao-Nan Shan Xu-Yong wei Rui Wang Chang-Ku Jia Li Zhuang Tian Shen Li-Min ding Zhi-Dan Xu Lai-Bang Luo Li-Bo Sun Guang-Ming Li Tai-Shi Fang Nan Jiang Kun zhang Zhao-Jie Su Zhi-Hai Peng Ren lang tao Jiang Qiang He Lin-Sen Ye Yang Yang yu-Ting He wen-Zhi Guo Liu-Gen lan Xu-Yong Sun dong Chen Zhi-Shui Chen Da-wei zhou Shao-jun Ye Qi-Fa Ye Min Tian Jian-Hua Shi Bo Wang Jiang Liu Qian Lu wei Rao Jin-Zhen Cai tao Lv Jia-yin Yang Pu-Sen Wang Lin Zhong Jing-Sheng Ma Qi-Gen Li Sheng-dong Wu Chang-Jiang Lu Cai-De Lu dong-Hua zhang Xuan Wang Zi-Qiang Li Mu-Jian Teng jun-Jie Li wen-tao Jiang Jian-Hua Li Quan-Bao zhang Ning-Qi Zhu Zheng-Xin Wang Kang He Qiang Xia Shao-Hua Song Zhi-Ren Fu wei qiu Guo-yue Lv Rui-Peng Song Ji-zhou Wang Zheng Wang Jian zhou Gang Chen ying-Peng Zhao Li Li Ze-Min Hu Qi-Jie Luo Zhong-zhou Si Bin Xie Xiao-Shun He Zhi-Yong Guo Shu-Sen Zheng Xiao Xu Department of Hepatobiliary and Pancreatic Surgery The Center for Integrated Oncology and Precision MedicineAffiliated Hangzhou First People’s HospitalZhejiang University School of MedicineHangzhou 310006China NHC Key Laboratory of Combined Multi-organ Transplantation Hangzhou 310003China Department of Hepatobiliary and Pancreatic Surgery Shulan(Hangzhou)HospitalZhejiang Shuren University School of MedicineHangzhou 310022China Department of Hepatobiliary and Pancreatic Surgery The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Department of Transplantation Jiangxi Provincial People’s Hospital Affiliated to Nanchang UniversityNanchang 330006China Liver Transplantation Center Beijing You’an HospitalCapital Medical UniversityBeijing 100069China Department of Hepatic Surgery National Clinical Research Center for Infectious DiseaseShenzhen Third People’s HospitalThe Second Affiliated Hospital of Southern University of Science and TechnologyShenzhen 518112China Department of General Surgery Xiang’an Hospital of Xiamen UniversityXiamen 361000China Deartment of Hepatobiliary and Pancreaticosplenic Surgery Beijing Chaoyang HospitalCapital Medical UniversityBeijing 100020China Department of Hepatic Surgery and Liver Transplantation Center The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630China Department of Hepatobiliary and Pancreatic Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Department of Liver Transplantation The Second Affiliated Hospital of Guangxi Medical UniversityNanning 530000China Institute of Organ Transplantation Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Institute of Hepatobiliary Diseases of Wuhan University Transplant Center of Wuhan UniversityHubei Key Laboratory of Medical Technology on TransplantationZhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Hepatobiliary Surgery The First Affiliated Hos

Mammalian target of rapamycin(m TOR) inhibitor as an attractive drug target with promising antitumor effects has been widely investigated. High quality clinical trial has been conducted in liver transplant(LT) recipients in Western countries. However, the pertinent studies in Eastern world are paucity. Therefore, we designed a clinical trial to test whether sirolimus can improve recurrence-free survival(RFS) in hepatocellular carcinoma(HCC) patients beyond the Milan criteria after LT. This is an open-labeled, single-arm, prospective, multicenter, and real-world study aiming to evaluate the clinical outcomes of early switch to sirolimus-based regimens in HCC patients after LT. Patients with a histologically proven HCC and beyond the Milan criteria will be enrolled. The initial immunosuppressant regimens are center-specifc for the frst 4-6 weeks. The following regimens integrated sirolimus into the regimens as a combination therapy with reduced calcineurin inhibitors based on the condition of patients and centers. The study is planned for 4 years in total with a 2-year enrollment period and a 2-year follow-up. We predict that sirolimus conversion regimen will provide survival benefts for patients particular in the key indicator RFS as well as better quality of life. If the trial is conducted successfully, we will have a continued monitoring over a longer follow-up time to estimate indicator of overall survival. We hope that the outcome will provide better evidence for clinical decision-making and revising treatment guidelines based on Chinese population data.

关键词： Sirolimus Immunosuppressive agents Hepatocellular carcinoma Liver transplantation Conversion

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射频技术在肝细胞癌临床应用中的选择、疗效与思考

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中华肝胆外科杂志 2011年第7期17卷 531-533页

作者：张炜炜孔文韬丁义涛周铁南京大学医学院附属鼓楼医院肝胆外科 210008

射频消融为治疗肝细胞癌的重要方法，具有微创性，可重复性，疗效确切等优点。对于不适宜手术及肝移植的早期肝细胞癌患者，许多中心已将其作为一种有效的手段。笔者回顾了射频治疗肝细胞癌的适应证、技术及疗效。我们体会，对于射频治... 详细信息

射频消融为治疗肝细胞癌的重要方法，具有微创性，可重复性，疗效确切等优点。对于不适宜手术及肝移植的早期肝细胞癌患者，许多中心已将其作为一种有效的手段。笔者回顾了射频治疗肝细胞癌的适应证、技术及疗效。我们体会，对于射频治疗，合理选择患者、优化治疗方案、完全灭活肿瘤与术后密切随访非常重要。新技术的应用，如人工胸水与腹水辅助穿刺、实时超声造影术中引导，腹腔镜与开腹射频，更有助于拓展射频治疗的适应证，减少术后并发症。

关键词：射频肝细胞癌疗效

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The first data release(DR1) of the LAMOST regular survey

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Research in Astronomy and Astrophysics 2015年第8期15卷 1095-1124页

作者： A-Li Luo Yong-Heng Zhao Gang Zhao Li-Cai Deng Xiao-wei Liu yi-Peng Jing Gang Wang Hao-Tong zhang Jian-Rong Shi Xiang-Qun Cui Yao-Quan Chu Guo-Ping Li Zhong-Rui Bai yue Wu Yan Cai Shu-yun Cao Zi-Huang Cao Jeffrey L.Carlin Hai-yuan Chen Jian-jun Chen Kun-Xin Chen Li Chen Xue-Lei Chen Xiao-Yan Chen ying Chen Norbert Christlieb Jia-Ru Chu Chen-zhou Cui yi-Qiao dong Bing Du dong-wei Fan Lei Feng Jian-Ning Fu Peng Gao Xue-Fei Gong Bo-Zhong Gu Yan-Xin Guo Zhan-wen Han Bo-Liang He Jin-Liang Hou Yong-Hui Hou wen Hou Hong-Zhuan Hu Ning-Sheng Hu Zhong-wen Hu Zhi-ying Huo Lei Jia Fang-Hua Jiang Xiang Jiang Zhi-Bo Jiang Ge Jin Xiao kong Xu kong Ya-Juan Lei Ai-Hua Li Chang-Hua Li Guang-wei Li Hai-Ning Li Jian Li Qi Li Shuang Li Sha-Sha Li Xin-Nan Li Yan Li yin-Bi Li Ye-Ping Li yuan Liang Chien-Cheng Lin Chao Liu Gen-Rong Liu Guan-Qun Liu Zhi-Gang Liu wen-Zhi Lu yu Luo yin-Dun Mao Heidi Newberg Ji-jun Ni Zhao-Xiang Qi Yong-jun Qi Shi-yin Shen Huo-Ming Shi Jing Song yi-Han Song ding-Qiang Su Hong-jun Su Zheng-Hong Tang Qing-Sheng tao yuan Tian Dan Wang Da-Qi Wang Feng-Fei Wang Guo-Min Wang Hai Wang Hong-Chi Wang Jian Wang Jia-Ning Wang Jian-Ling Wang Jian-Ping Wang jun-Xian Wang Lei Wang Meng-Xin Wang Shou-Guan Wang Shu-Qing Wang Xia Wang Ya-Nan Wang You Wang yue-Fei Wang You-Fen Wang Peng wei Ming-Zhi wei Hong Wu Ke-Fei Wu Xue-Bing Wu yu-Zhong Wu Xiao-Zheng Xing Ling-Zhe Xu Xin-Qi Xu Yan Xu Tai-Sheng Yan De-Hua Yang Hai-Feng Yang Hui-Qin Yang Ming Yang Zheng-qiu Yao Yong yu Hui yuan Hai-Bo yuan Hai-Long yuan wei-Min yuan Chao Zhai En-Peng zhang Hua-wei zhang Jian-Nan zhang Li-Pin zhang wei zhang Yong zhang Yan-Xia zhang Zheng-Chao zhang Ming Zhao Fang zhou Xu zhou Jie Zhu Yong-Tian Zhu Si-Cheng Zou Fang Zuo National Astronomical Observatories Chinese Academy of Sciences Department of Astronomy Peking University Shanghai Astronomical Observatory Chinese Academy of Sciences Nanjing Institute of Astronomical Optics & Technology National Astronomical ObservatoriesChinese Academy of Sciences University of Science and Technology of China Department of Physics Applied Physics and AstronomyRensselaer Polytechnic InstituteTroyNY 12180USA Department of Physics and Astronomy Earlham CollegeRichmondIN 47374USA Universitt Heidelberg Zentrum für AstronomieLandessternwarteKnigstuhl 1269117 HeidelbergGermany Department of Astronomy Beijing Normal University yunnan Observatories Chinese Academy of Sciences Purple Mountain Observatory Chinese Academy of Sciences

The Large sky Area Multi-Object Fiber Spectroscopic Telescope（LAMOST） general survey is a spectroscopic survey that will eventually cover approximately half of the celestial sphere and collect 10 million spectra of stars, galaxies and QSOs. Objects in both the pilot survey and the first year regular survey are included in the LAMOST DR1. The pilot survey started in October 2011 and ended in june 2012, and the data have been released to the public as the LAMOST Pilot Data Release in August 2012. The regular survey started in September 2012, and completed its first year of operation in june 2013. The LAMOST DR1 includes a total of 1202 plates containing 2 955 336 spectra, of which 1 790 879 spectra have observed signalto-noise ratio（SNR） ≥ 10. All data with SNR ≥ 2 are formally released as LAMOST DR1 under the LAMOST data policy. This data release contains a total of 2 204 696 spectra, of which 1 944 329 are stellar spectra, 12 082 are galaxy spectra and 5017 are quasars. The DR1 not only includes spectra, but also three stellar catalogs with measured parameters： late A,FGK-type stars with high quality spectra（1 061 918 entries）, A-type stars（100 073 entries）, and M-type stars（121 522 entries）. This paper introduces the survey design, the observational and instrumental limitations, data reduction and analysis, and some caveats. A description of the FITS structure of spectral files and parameter catalogs is also provided.

关键词： techniques: spectroscopic survey—data release—catalog

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人工胸腔积液超声引导经皮射频消融治疗膈顶部肝癌

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临床肿瘤学杂志 2007年第3期12卷 188-190页

作者：周铁仇毓东张炜炜周建新孔文韬丁义涛南京大学医学院附属鼓楼医院肝胆外科

目的：经皮超声引导射频消融是治疗肝脏肿瘤的一种有效的微创方法。但当肿瘤位于肝膈顶部时，由于肺脏气体的干扰肿瘤难以显示，治疗受到了限制。本文将评估射频结合人工胸腔积液治疗肝膈顶部肿瘤的安全性与可行性，并初步探讨其临床应... 详细信息

目的：经皮超声引导射频消融是治疗肝脏肿瘤的一种有效的微创方法。但当肿瘤位于肝膈顶部时，由于肺脏气体的干扰肿瘤难以显示，治疗受到了限制。本文将评估射频结合人工胸腔积液治疗肝膈顶部肿瘤的安全性与可行性，并初步探讨其临床应用价值。方法：15例原发性肝细胞肝癌患者，男性12例，女性3例，肿瘤均位于肝膈顶部。采用超声引导下冷循环射频结合人工胸腔积液的方法对肿瘤进行治疗。术后1月对所有治疗患者均进行增强CT或磁共振检查。结果：所有病例均安全完成射频治疗，未发生手术相关的并发症。随访时间2-18个月，11例患者存活。结论：人工胸腔积液结合经皮射频消融术可能是治疗肝脏膈顶部肿瘤一种安全可行的方法，值得进一步研究。

关键词：人工胸腔积液射频消融肝细胞性肝癌肝膈顶部

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Data release of the LAMOST pilot survey

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Research in Astronomy and Astrophysics 2012年第9期12卷 1243-1246页

作者： A-Li Luo Hao-Tong zhang Yong-Heng Zhao Gang Zhao Xiang-Qun Cui Guo-Ping Li Yao-Quan Chu Jian-Rong Shi Gang Wang Jian-Nan zhang Zhong-Rui Bai Xiao-Yan Chen Feng-Fei Wang Yan-Xin Guo Jian-jun Chen Bing Du Xiao kong Ya-Juan Lei yin-Bi Li yi-Han Song yue Wu Yan-Xia zhang Xin-Lin zhou Fang Zuo Peng Du Lin He wen Hou yi-Qiao dong Jian Li Guang-wei Li Shuang Li Jing Song yuan Tian Meng-Xin Wang Yong-Hui Hou Zhi-ying Huo Hong-Zhuan Hu Ning-Sheng Hu Zhong-wen Hu Lei Jia Fang-Hua Jiang Xiang Jiang Zi-Bo Jiang Ge Jin Ai-Hua Li Qi Li yin-Dun Mao Zheng-Hong Tang Qing-Sheng tao Liang-Ping Tu Da-Qing Wang Dan Wang Jian-Ping Wang Lei Wang Shou-Guan Wang Shu-Qing Wang Ya-Nan Wang You Wang yue-Fei Wang Ming-Zhi wei Xiang-Xiang Xue Xiao-Zheng Xing Ling-Zhe Xu Xin-Qi Xu Yan Xu De-Hua Yang Shi-Hai Yang Zheng-qiu Yao Yong yu Hui yuan Chao Zhai En-Peng zhang Jing zhang Li-Ping zhang weizhang Yong zhang Zhen-Chao zhang Ming Zhao Fang zhou Yong-Tian Zhu Jie Zhu Si-Cheng Zou National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China lal @ lamost o rg Nanjing Institute of Astronomical Optics and Technology National Astronomical ObservatoriesChinese Academy of Sciences Nanjing 210042 China University of Science and Technologyof China Hefei 230026 China Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 China Institute of Architecture Design and Research Chinese Academy of Sciences Beijing 100190China

This paper describes the data release of the LAMOST pilot survey, which includes data reduction, calibration, spectral analysis, data products and data access. The accuracy of the released data and the information about the FITS headers of spectra are also introduced. The released data set includes 319 000 spectra and a catalog of these objects.

关键词： techniques: spectroscopic survey — data reduction — data release

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腹腔镜超声在经皮射频消融术治疗肝肿瘤中的应用价值

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中华医学超声杂志（电子版） 2012年第9期9卷 64-66页

作者：邱君斓周铁孔文韬蒋智明沈祎张炜炜南京大学医学院附属鼓楼医院普外科超声中心南京210008

目的探讨腹腔镜超声在经皮射频消融术治疗肝肿瘤中的应用价值。方法 31例不能耐受开腹手术的肝癌患者,常规超声均无法经皮定位病灶,行经皮射频消融术时术中均在腹腔镜超声下引导穿刺,并动态观察手术进程。结果 31例肝癌患者均在腹腔镜... 详细信息

目的探讨腹腔镜超声在经皮射频消融术治疗肝肿瘤中的应用价值。方法 31例不能耐受开腹手术的肝癌患者,常规超声均无法经皮定位病灶,行经皮射频消融术时术中均在腹腔镜超声下引导穿刺,并动态观察手术进程。结果 31例肝癌患者均在腹腔镜超声引导下完成经皮射频消融术。其中7例为术前CT或MRI发现而常规超声无法扫查的膈顶部病灶,3例为术前未发现小病灶,1例排除术前MRI诊断的假阳性病灶。31例肝癌患者腹腔镜手术顺利,无术中死亡,术后未出现出血、感染等并发症,5例出现一过性发热,4例出现恶心,3例出现轻微腹痛。术后随访6个月内无1例复发。结论腹腔镜超声可检出术前影像学检查遗漏的肝癌小病灶、定位常规超声盲区处肝癌病灶并引导经皮射频消融术。腹腔镜超声可以辅助完成不能耐受开腹手术、常规经皮超声又无法定位治疗的肝癌患者的经皮射频消融治疗。

关键词：腔内超声检查腹腔镜检查肝肿瘤监测,手术中射频消融

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