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Combined small bowel and reduced auxiliary liver transplantation:case report

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World Journal of Gastroenterology 2002年第5期8卷 956-960页

作者： Wei-Jie Zhang Dun-Gui Liu qi-fa ye Bo Sha fan-Jun Zhen hui Gun sui-sheng xia institute of organ transplantation,tongji hospital,huazhong university of science and technology,wuhan 430030,Hubei Province,china institute of organ transplantation Tongji Hospital Huazhong University of Science and Technology Wuhan 430030 Hubei Province China. wjzhang@***

AIM: To present a case of combined small bowel andreduced auxiliary liver ***: A 55-year-old patient with short bowelsyndrome and TPN-related liver dysfunction received smallbowel transplantation combined with a reduced auxiliaryliver graft. A liver was added to restore the patient′s liverfunction and to protect the intestinal allograft from *** own liver was not ***: Without donor pretreatment and by conventionalimmunosuppresive therapy following transplantation, thepatient experienced had only one episode of mild intestinalrejection, which was easily reversed by treatment withMethylprednisolone. No liver rejection ***, the patient died of heart and lung failure30d after transplantation, despite successful graftreplacement. Histopathologic examination of specimens afterdeath demonstrated normal structure in both intestinal andliver ***: The auxiliary liver graft might play a role inpreventing intestinal allograft rejection. However, theobservation period in this case is short. Further study isneeded to determine the risks, effect on the protecting thesmall-bowel from rejection, and feasibility of generalapplication of this procedure.

关键词：小肠移植肝移植病例短肠综合征 TPN相关性肝功能不良合并症

Induction of immune tolerance with heart-thymus composite allotransplantation in rats

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Journal of Central South university of technology 2005年第Z1期12卷 331-336页

作者： XIONG Hai-bo xia sui-sheng wen Hao HUANG Zu-fa ye qi-fa medical Academy of transplantation the Third Xiangya Hospital Central South University Changsha 410013 China Institute of Transplantation Tongji Hospital Huazhong Science and Technological University Wuhan 430030 China Department of General Surgery the First Affiliated Hospital Xinjiang Medical University Urumqi 830054 China Medical Academy of Transplantation the Third Xiangya Hospital Central South University Changsha 410013 China Medical Academy of Transplantation the Third Xiangya Hospital Central South University Changsha 410013 China

Objective To study on the role of thymus transplantation for heart allograft in rats. Methods Vascularized heart-thymus combined transplantation was performed with microsurgical technique. Graft survival, histopathology, level of IL-2, IL-4 and its mRNA expression in serum and cardiac grafts were investigated. Results Heart-thymus combined transplantation achieved effect in the prolongation of cardiac graft survival with short-term administration of cyclosporine. Conclusions Vascularized thymus transplantation induced immune tolerance in thymectomized rats.

关键词： thymus transplantation immune tolerance rejection rat

Establishment and improvement of model of vascularized heart-thymus composite transplantation in rats

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Journal of Central South university of technology 2005年第Z1期12卷 347-349页

作者： XIONG Hai-bo xia sui-sheng wen Hao HUANG Zu-fa ye qi-fa medical Academy of transplantation the Third Xiangya HospitalCentral South UniversityChangsha 410013China institute of transplantation Tongji HospitalHuazhong Science and Technological UniversityWuhan 430030China Department of General Surgery the First Affiliated HospitalXinjiang Medical UniversityUrumqi 830054China

Objective To establish and improve the model of heart-thymus composite *** Vascularized both lobes of the thymus is transplanted heterotopically with the heart as a composite graft in *** technique was developed and assessed,and viability of the grafts was evaluated *** Donor operation costed 38.5±3.52 min,vascular anastomosis costed 25.0±3.28 min,operating successful rate was 90%,acute rejection was observed in SD-Wistar group,viable thymus with normal microarchitecture was maintained in Wistar-Wistar *** The improved novel technique for combined heart-thymus transplantation is a valuable method for study of the role of thymus in transplantation immunity.

关键词： heart thymus composite transplantation rat animal model transplantation immunity

Effect of FTY720 and ICAM-1 mAb mono and combination therapy in cardiac allo-transplantation in rats

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Journal of Central South university of technology 2005年第Z1期12卷 343-346页

作者： XIONG Hai-bo HUANG Zu-fa xia sui-sheng ye qi-fa wen Hao institute of transplantation the Third Xiangya HospitalCentral South UniversityChangsha 410013China Department of General Surgery the First Affiliated HospitalXinjiang Medical UniversityUrumqi 830054China institute of transplantation Tongji Hospital of Huazhong Science and Technological UniversityWuhan 430030China

Objective To observe the effect of FTY720 and ICAM-1 mAb mono and combination therapy in cardiac silo-transplantation in *** Rats were randomly assigned to 9 groups,heart allo-transplantation were performed in abdominal site with micro-surgical *** with allografts were treated with different doses of FTY720 and(or)ICAM-1 *** survival,histopathology andlevel of serum IL-2,IFN-γ,IL-4,IL-10were *** Low doses of FTY720(lmg/kg)combined with ICAM-1 mAb achieved synergistic effect in the prolongation of cardiac graft survival,combination index CD=*** Concomitant therapy of FTY720 and ICAM-1 mAb achieved a synergistic effect in the prolongation of heart allograft survival in rats.

关键词： FTY720 ICAM-1 mAb synergy rat heart transplantation immune tolerance rejection

CEPC Technical Design Report

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Radiation Detection technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed xiaocong Ai Abid Aleem Wolfgang Altmannshofer fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci xiao-Jun Bi Yuanjie Bi Tianjian Bian fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen xiang Chen xiaoyu Chen Xin Chen xun Chen xurong Chen ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti wen Han Chiu Guk Cho Ming-Chung Chu xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH university of science and technology Faculty of Physics and Applied Computer ScienceKrakow Anhui university HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu university Institute of ScienceVaranasi Bandirma Onyedi Eylul university Bandirma Beihang university Beijing Beijing Computational science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research institute Co. LtdBeijing Beijing institute of technology Beijing Beijing Normal university Beijing Brown university ProvidenceRI Budker institute of Nuclear Physics Novosibirsk Cadi Ayyad university Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo university Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central china Normal university WuhanHubei Central South university ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan china academy of engineering physics MianyangSichuan china building materials academy Beijing china Center of Advanced science and technology Beijing china institute of Atomic Energy Beijing china Jiliang university HangzhouZhejiang china Nuclear Instrument CO. LTDBeijing china university of Geosciences Beijing china university of Geosciences WuhanHubei china university of Mining and technology XuzhouJiangsu china West Normal university NanchongSichuan Chongqing university Department of PhysicsChongqing Chulalongkorn university Bangkok City university of Hong Kong Department of PhysicsHong Kong Cockcroft institute Daresbury Cornell university IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu university DalianLiaoning Dalian university of technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint institute for Nuclear Research(DLNP JINR) Dubna East china university Of science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by china,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise