检索结果-南通市图书馆

Bibliometric analysis of olaparib and pancreatic cancer from 2009 to 2022:A global perspective

World Journal of Gastrointestinal Oncology 2024年第11期16卷 4489-4505页

作者： Xu Feng Yi-Han Chai Ke-Xin jiang wen-bin jiang wen-Chao Chen Yu Pan Department of General Surgery Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310016Zhejiang ProvinceChina

BACKGROUND Genetic screening for breast cancer gene 1(BRCA)1/2 mutations can inform breast/ovarian/pancreatic cancer patients of suitable therapeutic *** to seven percent of pancreatic cancer patients have germline BRCA *** genes aid in DNA repair,especially homologous recombination,which impacts genomic stability and cancer cell ***1 regulates the cell cycle,ubiquitination,and chromatin remodeling,whereas BRCA2 stimulates the immune *** predict the efficacy of platinum chemotherapy or polymerase(PARP)inhibitors such as *** To determine the trends and future directions in the use of olaparib for pancreatic cancer *** To evaluate the trends in how olaparib works in pancreatic cancer,we performed a bibliometric *** hundred and ninety-six related publications were accessed from the Web of Science Core Collection and were published between 2009 and *** analytic parameters included publications,related citations,productive countries and institutes,influential authors,and keyword *** This study visualizes and discusses the current research,including the present global trends and future directions in olaparib and pancreatic ***,this study sheds light on optimizing the use of olaparib in pancreatic cancer treatment,Feng X et *** use of olaparib in pancreatic cancer WJGO https://*** 4490 November 15,2024 Volume 16 Issue 11 offering valuable guidance for researchers in this *** Our findings identified trends in olaparib and pancreatic cancer,with China and the USA leading and with global cooperation tightening.O'Reilly EM's team and Memorial Sloan-Kettering had the highest *** Journal of Clinical Oncology was the most cited *** PARP inhibitors are emerging,and combination therapy is suggested for future therapeutic trends.

关键词： Olaparib Pancreatic cancer Bibliometric analysis Breast cancer susceptibility gene Poly(adenosine diphosphate-ribose)polymerase

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

FDGLib: A Communication Library for Efficient Large-Scale Graph Processing in FPGA-Accelerated Data Centers

引用

Journal of Computer Science & Technology 2021年第5期36卷 1051-1070页

作者： Yu-Wei Wu Qing-Gang Wang Long Zheng Xiao-Fei Liao Hai Jin wen-bin jiang Ran Zheng Kan Hu National Engineering Research Center for Big Data Technology and System School of Computer Science and Technology Huazhong University of Science and TechnologyWuhan 430074China Services Computing Technology and System Laboratory School of Computer Science and Technology Huazhong University of Science and TechnologyWuhan 430074China Cluster and Grid Computing Laboratory School of Computer Science and TechnologyHuazhong University of Science and TechnologyWuhan 430074China

With the rapid growth of real-world graphs,the size of which can easily exceed the on-chip(board)storage capacity of an accelerator,processing large-scale graphs on a single Field Programmable Gate Array(FPGA)becomes *** multi-FPGA acceleration is of great necessity and *** cloud providers(e.g.,Amazon,Microsoft,and Baidu)now expose FPGAs to users in their data centers,providing opportunities to accelerate large-scale graph *** this paper,we present a communication library,called FDGLib,which can easily scale out any existing single FPGA-based graph accelerator to a distributed version in a data center,with minimal hardware engineering *** provides six APIs that can be easily used and integrated into any FPGA-based graph accelerator with only a few lines of code *** the torus-based FPGA interconnection in data centers,FDGLib also improves communication efficiency using simple yet effective torus-friendly graph partition and placement *** interface FDGLib into AccuGraph,a state-of-the-art graph *** results on a 32-node Microsoft Catapult-like data center show that the distributed AccuGraph can be 2.32x and 4.77x faster than a state-of-the-art distributed FPGA-based graph accelerator ForeGraph and a distributed CPU-based graph system Gemini,with better scalability.

关键词： data center accelerator graph processing distributed architecture communication optimization

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Factors associated with the nurses’intent to stay in China,Japan,and Korea:an integrative review

引用

Frontiers of Nursing 2020年第3期7卷 269-278页

作者： Ting Xue wen-bin jiang Meng-Di Ma Jie Zhang Ming-Hui Lu Yong-Mei jiang School of Nursing Qingdao UniversityQingdaoShandong 266021China Nursing Department The Affiliated Hospital of Qingdao UniversityQingdaoShandong 266000China Emergency Department Qilu Hospital of Shandong University(Qingdao)QingdaoShandong 266035China Intensive Care Unit Tianjin Medical University General Hospital Airport HospitalTianjin300300China

Objective:Nurse’s dimission and attrition are globally considered as a public health ***,few studies have focused on the nurse shortage from the perspective of intent to stay,as previous studies have focused only on why they *** purpose of this study was to conduct an integrative review of the factors connected with why nurses in China,Japan,and Korea stay in their current ***:The review was done using three databases namely CNKI,Wanfang,and Web of *** relevant studies published by Chinese,Japanese,and Koreans from 2010 were also included in this *** screening and data extraction were performed by the two researchers,and the qualitative research methods were used for ***:A total of 17 studies were analyzed in this review and of these two were qualitative and 15 were *** themes and six sub-themes emerged from the synthesization of the data of 17 studies,which will help us to find the factors for nurses’intent to *** three aspects such as professional characteristics,nurses’individual characteristics,and organizational factors are the main contributing factors of nurses’intent to ***:This integrated review has thrown some important factors about nurses’intent to *** is increasingly clear that when(1)nurses have a good professional status,(2)nurses could enjoy a good working relationship,(3)the workplace could meet the needs of personal development,and(4)nurses have good organizational support and excellent leaders,they are inclined to stay in their current *** need to adopt targeted measures to improve nurses’intent to stay and to provide a practical reference for health care institutions and managers in different countries and areas to increase the retention rate of nurses and to alleviate the current situation of nurse shortage.

关键词： nurse intent to stay China Japan Korea nursing management nurse shortage

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Purification and characterization of cholecystokinin from the skin of salamander Tylototriton verrucosus

引用

Zoological Research 2015年第3期36卷 174-177页

作者： wen-bin jiang Ma HAKIM Lei LUO Bo-wen LI Shi-Long YANG Yu-Zhu SONG Ren LAI Qiu-Min LU Faculty of Life Science and Technology Kunming University of Science and Technology Kunming Yunnan 650500 China Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences & Yunnan Province KunmingInstitute of Zoology Kunming Yunnan 650223 China

As a group of intestinal hormones and neurotransmitters, cholecystokinins（CCKs） regulate and affect pancreatic enzyme secretion, gastrointestinal motility, pain hypersensitivity, digestion and satiety, and generally contain a DYMGWMDFG sequence at the C-terminus. Many CCKs have been reported in mammals. However, only a few have been reported in amphibians, such as Hyla nigrovittata, Xenopus laevis, and Rana catesbeiana, with none reported in urodele amphibians like newts and salamanders. Here, a CCK called CCK-TV was identified and characterized from the skin of the salamander Tylototriton verrucosus. This CCK contained an amino acid sequence of DYMGWMDF-NH2 as seen in other CCKs. A c DNA encoding the CCK precursor containing 129 amino acid residues was cloned from the c DNA library of T. verrucosus skin. The CCK-TV had the potential to induce the contraction of smooth muscle strips isolated from porcine gallbladder, eliciting contraction at a concentration of 5.0x10-11 mol/L and inducing maximal contraction at a concentration of 2.0x10-6 mol/L. The EC50 was 13.6 nmol/L. To the best of our knowledge, this is the first report to identify the presence of a CCK in an urodele amphibian.

关键词： Cholecystokinin Salamander Skin Amphibian

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Synthesis,Crystal Structure and Magnetic Properties of the New Quaternary Thiophosphate Rb_2FeP_2S_6

引用

Chinese Journal of Structural Chemistry 2018年第10期37卷 1563-1571页

作者： SU Yong-Fei LIU bin-wen,jiang Xiao-Ming ZENG Hui-Yi LIN Yang-Jie GUO Guo-Cong State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences Fuzhou 350002 China

A new quaternary thiophosphate Rb_2FeP_2S_6 was synthesized by the alkali metal halide flux *** compound crystallizes in the monoclinic space group P2_1/c（No.14） with a = 6.042（3）,b = 12.338（6）,c = 9.045（4）？,b = 124.25（2）°,V = 557.3（5）？~3 and Z = *** structure features 1-D infinite _∞~1[FeP_2S_6]^（2-） chains and counter cations Rb~＋.It shows a band gap of 2.03 *** nearest intra-chain Fe^（2＋） cations are antiferromagnetically coupled with each other,and there are weak ferromagnetic-like interactions between neighboring _∞1[FeP_2S_6]（2-） chains,resulting in two successive magnetic phase transitions.

关键词： crystal structure synthesis antiferromagnetic thiophosphate

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Laparoscopic vs open radical resection in management of gallbladder carcinoma:A systematic review and meta-analysis

引用

World Journal of Clinical Cases 2023年第27期11卷 6455-6475页

作者： Shilin He Tu-Nan Yu Jia-Sheng Cao Xue-Yin Zhou Zhe-Han Chen wen-bin jiang Liu-Xin Cai Xiao Liang Department of General Surgery Sir Run-Run Shaw Hospital of Zhejiang University School of MedicineHangzhou 310016Zhejiang ProvinceChina School of Medicine Wenzhou Medical UniversityWenzhou 325035Zhejiang ProvinceChina The Second Clinical Medical College Zhejiang Chinese Medical UniversityHangzhou 310053Zhejiang ProvinceChina Department of Hepatobiliary Surgery Fuyang First People’s Hospital Affiliated to Zhejiang Chinese Medical UniversityHangzhou 311400Zhejiang ProvinceChina

BACKGROUND Radical resection offers the only hope for the long-term survival of patients with gallbladder carcinoma(GBC)above the T1b ***,whether it should be performed under laparoscopy for GBC is still *** To compare laparoscopic radical resection(LRR)with traditional open radical resection(ORR)in managing *** A comprehensive search of online databases,including Medline(PubMed),Cochrane Library,and Web of Science,was conducted to identify comparative studies involving LRR and ORR in GBCs till March 2023.A meta-analysis was subsequently *** A total of 18 retrospective studies were *** the long-term prognosis,the LRR group was comparable with the ORR group in terms of overall survival and tumor-free survival(TFS).LRR showed superiority in terms of TFS in the T2/tumor-node-metastasis(TNM)Ⅱstage subgroup vs the ORR group(P=0.04).In the short-term prognosis,the LRR group had superiority over the ORR group in the postoperative length of stay(POLS)(P<0.001).The sensitivity analysis showed that all pooled results were *** The meta-analysis results show that LRR is not inferior to ORR in all measured outcomes and is even superior in the TFS of patients with stage T2/TNMⅡdisease and *** with sufficient laparoscopic experience can perform LRR as an alternative surgical strategy to ORR.

关键词： Gallbladder carcinoma Laparoscopic radical resection Open radical resection Outcome Systematic review Meta-analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Comparative Assay of Hepatitis B and C Virus Infection Markers by Different Assay Kits^1

引用

Biomedical and Environmental Sciences 2000年第3期13卷 198-204页

作者： SHINICHIRO SHIMBO, ZHANG ZUO wen, QU jiang bin , TAKAO WATANABE  , HARUO MAKATSUKA △, NAOKO MATSUDA INOGUCHI △, KAE HIGASHIKAWA □, AND MASAYUKI IKEDA △, 2 Department of Food and Nutrition, Kyoto Women’s University, Kyoto 6 Kyoto Women’s University 日本 Kyoto 6058501 山东医科大学山东济南 250012 Miyagi University of Education 日本 Sendai 9800845 Miyagi University 日本 Taiwa cho 9813298 Kyoto Industrial Health Association 日本 Kyoto 6048472

In order to compare sensitivity of EIA and RIA assay kits for hepatitis B and C virus (HBV and HCV, respectively) infection markers, 100 serum samples in total were collected form 50 adult women each in urban and rural areas in northeast China. The number of positive cases to the three infection markers on HBV (i.e., HBsAg +, anti HBs +, and anti HBc +) and the one on HCV (anti HCV +) were examined in two laboratories, i.e., in Laboratory A with EIA kits produced in China and in Laboratory B with RIA kits. HCV infection positivity (anti HCV +) was examined by EIA kits in both laboratories, but from different sources in and outside of China, respectively. The assay in Laboratory A gave 2 HBsAg + cases out of the 100 cases examined, whereas there were 9 positive cases in Laboratory B. In contrast, 19 cases were positive to anti HCV when examined in Laboratory A, and there were 3 cases in Laboratory B. Thus, the kits used in Laboratory A gave fewer HBsAg + and more anti HCV + cases than the kits used in Laboratory B. The prevalence of anti HBs + or anti HBc + and cases did not differ when assayed in the two laboratories with EIA and RIA kits, respectively. The agreement of positive and negative findings between the two sets of testing were 93%, 93%, 93%, 86% and 82% for HBsAg, anti HBs, anti HBc, HBV (i.e., either positive to anyone of the three markers or negative to all three markers), and anti HCV, respectively. The implication of the observation on epidemiology on HBV and HCV infection prevalence was discussed.

关键词： Wang Li Zhang Markers by Different Assay Kits~1 Comparative Assay of Hepatitis B and C Virus Infection Chen

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Multi-slice three-dimensional spiral CT cholangiography: a new technique for diagnosis of biliary diseases

引用

Hepatobiliary & Pancreatic Diseases International 2002年第4期1卷 595-603页

作者： Ai-Min Xu Hong-Yan Cheng wen-bin jiang Dong Chen Yu-Chen Jia Meng-Chao Wu the Department of Radiology, Eastern Hepatobiliary Surgery Hospital, Shanghai 200438, China Department of Radiology Eastern Hepatobiliary Surgery Hospital Shanghai 200438 China. xuarmy@***

Objective: To validate multi-slice three-dimensional spiral CT cholangiography (3-D CTC) in clinical di- agnosis of biliary diseases. Methods: This study included 146 patients with bili- ary diseases, involving 73 cases of biliary tumor, 87 cases of radioparent calculus, 12 cases of post cholan- gio-jejunostomy and one case of congenital choledo- chocyst. The data of thin-slice volumetric CT scan were sent to the workstation (GE Advantage Win- dows 3. 1). Rational 3-D CTC including maximum intensity projection, minimum intensity projection, surface shaded display, CT virtual endoscopy and ray sumption was performed. The diagnostic accura- cy of 3-D CTC was compared with that of conven- tional CT, ultrasonography and endoscopic retro- grade cholangiopancreaticography (ERCP). Results: Different biliary diseases showed distinct ima- ging manifestations on 3-D CTC, As a new technique for assessing the status of post cholangio-jejunosto- my, 3-D CTC was superior to conventional CT, ul- trasonography and ERCP in diagnosis of negative bil- iary calculus, extrahepatic cholangiocarcinoma, cancer embolus of the biliary duct, carcinoma of the pancreas head and periampullar carcinoma. It was also superior to conventional CT, ultrasonography or equal to ERCP in diagnosis of hilar cholangiocarcino- ma, but inferior to conventional CT and ultrasonog- raphy in diagnosis of gallbladder cancer. Conclusion: 3-D CTC as a non-invasive and sensitive technique for the diagnosis of biliary diseases with high diagnostic accuracy will greatly increase the de- tection rate of biliary diseases.

关键词： X-ray computed tomography cholangiography bile duct

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

P45 technology reveals bow-and-arrow sign in human ankle

引用

Chinese Medical Journal 2020年第11期133卷 1373-1374页

作者： wen-bin jiang Chan Li Shi-Zhu Sun Wei Chen Sheng-Bo Yu Hong-Jin Sui Department of Anatomy Dalian Medical UniversityDalianLiaoning 116044China Department of Orthopedic Surgery The Third Hospital of Hebei Medical UniversityShijiazhuangHeibei 050051China

To the Editor:Recent studies have shown that the morphology of bone in vivo,including the shape,diameter,length,curve,and alignment of the bone,adapt to longterm loads both before and after skeletal *** deformation and rate are different according to the magnitude of strain,the mode of action,position and the quality of bone of the strain,which is named by law of dynamic deformation of bone.[1]Here,we found that the existence of circular bone trabecula in the calcaneus by P45 plastination *** might be caused by the force conduction to the flexor digitorum brevis during the contraction of the triceps surae according to this law.

关键词： conduction circular contraction

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Blunt Dissection： A Solution to Prevent Bile Duct Injury in Laparoscopic Cholecystectomy

引用

Chinese Medical Journal 2015年第23期128卷 3153-3157页

作者： Xiu-Jun Cai Han-Ning Ying Hong Yu Xiao Liang Yi-Fan Wang wen-bin jiang Jian-Bo Li Lin Ji Department of General Surgery Sir Run Run Shaw Hospital Medical College of Zhejiang University Hangzhou Zhejiang 310016 China

Background： Laparoscopic cholecystectomy （LC） has been a standard operation and replaced the open cholecystectomy （OC） rapidly because the technique resulted in less pain, smaller incision, and faster recovery. This study was to evaluate the value of blunt dissection in preventing bile duct injury （BDI） in laparoscopic cholecystectomy （LC）. Methods： From 2003 to 2015, LC was performed on 21,497 patients, 7470 males and 14,027 females, age 50.3 years （14-84 years）. The Calot＇s triangle was bluntly dissected and each duct in Calot＇s triangle was identified before transecting the cystic duct. Results： Two hundred and thirty-nine patients （1.1%） were converted to open procedures. The postoperative hospital stay was 2.1 （0-158） days, and cases （46%） had hospitalization days of 1 day or less, and 92.8% had hospitalization days of 3 days or less; BDI was occurred in 20 cases （0.09%） including 6 cases of common BDI, 2 cases of common hepatic duct injury, l case of fight hepatic duct injury, I case of accessory fight hepatic duct, 1 case of aberrant BDI l case ofbiliary stricture, 1 case ofbiliary duct perforation, 3 cases ofhemobilia, and 4 cases of bile leakage. Conclusion： Exposing Calot＇s triangle by blunt dissection in laparoscopic cholecystectomy could prevent intraoperative BD1.

关键词： Bile Duct Injury Blunt Dissection Laparoscopic Cholecystectomy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：