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A chain-like compound of Si@CNT nanostructures and MOF-derived porous carbon as an anode for Li-ion batteries

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International Journal of Minerals,Metallurgy and Materials 2021年第10期28卷 1611-1620页

作者： Ying-jun Qiao Huan Zhang Yu-xin Hu Wan-peng Li wen-jing liu Hui-ming Shang Mei-zhen Qu Gong-chang Peng Zheng-wei Xie Chengdu Institute of Organic Chemistry Chinese Academy of SciencesChengdu 610041China University of Chinese Academy of Sciences Beijing 100039China

Silicon anodes are considered to have great prospects for use in batteries;however,many of their defects still need to be *** preparation of hybrid materials based on porous carbon is one of the effective ways to alleviate the adverse impact resulting from the volume change and the inferior electronic conductivity of a silicon ***,a chain-like carbon cluster structure is prepared,in which MOF-derived porous carbon acts as a shell structure to integrally encapsulate Si nanoparticles,and CNTs play a role in connecting carbon *** on the exclusive structure,the carbon shell can accommodate the volume expansion more effectively,and CNTs can improve the overall stability and *** resulting composite reveals excellent rate capacity and enhanced cycling stability;in particular,a capacity of 732 mA·h·g^(-1) at 2 A·g^(-1) is achieved with a reservation rate of 72.3% after cycling 100 times at 1 A·g^(-1).

关键词： silicon carbon nanotubes metal-organic framework Li-ion batteries

Changes of the trace metals in ice core during 1915-2016 in coastal eastern Antarctica

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Advances in Climate Change Research 2024年第4期15卷 596-608页

作者： jing-wen liu Chuan-Jin LI Gui-Tao SHI Yan liu Zhi-Heng DU Ming-Hu DING Shao-Peng GAO Cun-De XIAO Shi-Chang KANG Bo SUN State Key Laboratory of the Cryosphere Science Northwest Institute of the Eco-Environment and ResourcesChinese Academy of SciencesLanzhou730000China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory for Polar Science of State Oceanic Administration Polar Research Institute of ChinaShanghai 200136China Key Laboratory of Geographic Information Science(Ministry of Education) School of Geographic Sciences and Institute of Eco-ChongmingEast China Normal UniversityShanghai 200241China Institute of Tibetan Plateau and Polar Regions Meteorology Chinese Academy of Meteorological SciencesBeijing 100081China Key Laboratory of Tibetan Environment Changes and Land Surface Processes Instituie of the Tibetan PlateauChinese Academy of SciencesBeijing 100101China State Key Laboratory of Earth Surface Processes and Resource Ecology Beijing Normal UniversityBeijing 100875China

Antarctic trace metal records provide important information for grasping the influence of human activities on the environment over the last *** CA2016-75 ice core is located along the East Antarctic Zhongshan Station-Dome A,enhances the record of metals research in the East Antarctic region,and its high-resolution supplies data support for the study of high-frequency climatic drivers and the effect of human activities on the Antarctic environment.A thorough dataset on seven trace metals(Al,Fe,Mn,Cu,Zn,Ba and Pb)in a coastal ice core in eastern Antarctica during the previous 102 years(1915-2016)is presented in this *** has the lowest concentration(9.51±20.95 pg g^(-1)),and Ba has the highest concentration(36.57±51.35 ng g^(-1)).Notable variations are observed between the pre-1968 AD and post-1968 AD phases for Mn,Zn and *** abrupt,remarkable increase in the concentrations coincided with the change of metal smelting production in the southern *** addition to this,it may also be related to local Antarctic scientific research *** and Fe,the primary crustal elements,are essentially obtained from soil dust;Cu shows high crustal enrichment factors(EFc,>10),indicating that it is notably affected by anthropogenic ***,the anthropogenic activities in the Southern Hemisphere have had an impact on lead deposition in *** study not only enriches the trace metal historical record along the Zhongshan Station-Dome A but also provides a high-resolution ice core record,which is very crucial for the reconstruction of trace metal concentration changes in the last 100 years.

关键词： Eastern Antarctica Ice core Trace metals Human activities

水平偏心受荷桩基础在砂土中的群桩效应（英文）

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2019年第4期20卷 243-257页

作者： Ling-gang KONG Ji-ying FAN jing-wen liu Yun-min CHEN Institute of Geotechnical Engineering College of Architectural and Civil Engineering Zhejiang University Geoengineering Centre at Queen's-RMC Queen's UniversityKingston Bureau of Housing and Urban-Rural Development of Chengdu

目的:p乘子法在水平受荷群桩非线性静力响应分析中应用广泛,是定量表征水平受荷群桩中群桩效应影响的有效方法。本文基于水平偏心受荷群桩中群桩效应的理论、实验和数值分析成果,提出一套定量表征水平偏心受荷群桩群桩效应的p乘子经验算... 详细信息

目的:p乘子法在水平受荷群桩非线性静力响应分析中应用广泛,是定量表征水平受荷群桩中群桩效应影响的有效方法。本文基于水平偏心受荷群桩中群桩效应的理论、实验和数值分析成果,提出一套定量表征水平偏心受荷群桩群桩效应的p乘子经验算法(为区别于水平受荷群桩p乘子,该p乘子被命名为广义p乘子)。创新点:1.提出表征水平偏心受荷群桩群桩效应的p乘子经验算法;2.分析水平偏心受荷群桩中任意两桩的运动规律,给出两桩运动方向角变化范围;3.给出两桩间产生桩-土-桩相互作用的临界条件。方法:1.通过理论分析给出两桩运动方向角变化范围和两桩间产生桩-土-桩相互作用的临界条件;2.利用离心模型实验和数值模拟获得折减系数随两桩运动方向的变化规律;3.采用数值拟合方法在相互作用存在的方向角范围内建立折减系数随两桩运动方向与两桩连线夹角之间的定量关系。结论:1.水平偏心受荷的两根桩,前桩运动方向与两桩连线之间的夹角η介于0°到90°之间,而后桩夹角θ介于-90°到90°之间;2.η和θ组合存在一个范围,在该范围内两桩存在相互作用,且相互作用对后桩的影响往往大于对前桩的影响;3.实验案例验证了本文提出的广义p乘子经验计算公式的合理性。

关键词：水平偏心群桩效应广义p乘子折减系数离心实验

P波斜入射形成的动应力路径及影响因素分析（英文）

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2017年第10期18卷 776-792页

作者： Bo HUANG Qi-qun LI Dao-sheng LING jing-wen liu Yu WANG Institute of Geotechnical Engineering Zhejiang University MOE Key Laboratory of Soft Soils and Geoenvironmental Engineering Zhejiang University CCCC-FHDI Engineering Co. Ltd.

目的:研究P波斜入射下的地基动应力路径,探讨其影响因素和可能变化范围,为进一步研究斜入射地震波作用下场地动力响应奠定理论基础。创新点:1.从数学上证明斜入射P波在任一深度的地基中形成的应力路径在剪应力分量(偏差正应力-水平剪应... 详细信息

目的:研究P波斜入射下的地基动应力路径,探讨其影响因素和可能变化范围,为进一步研究斜入射地震波作用下场地动力响应奠定理论基础。创新点:1.从数学上证明斜入射P波在任一深度的地基中形成的应力路径在剪应力分量(偏差正应力-水平剪应力)组成的平面中为一个斜椭圆;2.分析了P波入射角、土体泊松比和单位波长深度对斜椭圆应力路径形状与大小的影响。方法:1.基于半无限弹性空间的地震波传播理论,考虑地震波在自由界面的反射,推导土体中任一深度处由P波斜入射产生的动应力,并表示成由剪应力分量组成的平面下的应力路径(公式(9))及该应力路径的特征参数表达式(公式(A12)^(A14));2.通过控制变量法,分析参数敏感性(图7、9、10和12)。结论:1.虽然证实P波斜入射引起的应力路径为斜椭圆形式,但在地基深度、入射波频率和波速的特定组合下,斜椭圆仍可从斜线一直变化到圆形,形式较为多样化;2.P波斜入射角度在30?~60?时引起的动偏应力幅最大,最大可达同等条件下其它入射角产生的动应力幅的2倍以上;3.斜入射角大于45?后,斜椭圆路径形状几乎不随入射角改变,在研究范围内以竖直扁椭圆形为主;4.土体饱和度大于70%时,泊松比的变化对土体斜椭圆路径形状影响不大,但动应力幅随泊松比增大而显著降低。

关键词：近场地震 P波斜入射弹性半空间动应力路径

Design of 50 MeV proton microbeam based on cyclotron accelerator

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Nuclear Science and Techniques 2023年第6期34卷 55-68页

作者： Hong-Jin Mou Guang-Bo Mao Jin-Quan Zhang Can Zhao Jin-Long Guo wen-jing liu Ru-Qun Wu Cheng Shen Lei Zhang Jun-Shuai Li Guang-Hua Du Material Research Center Institute of Modern PhysicsChinese Academy of SciencesLanzhou730000China School of Materials and Energy Lanzhou UniversityLanzhou730000China University of Chinese Academy of Sciences Beijing100049China

High-energy proton microbeam facilities are powerful tools in space science,biology and cancer therapy *** primary limitations of the 50 MeV proton microbeam system are the poor beam quality provided by the cyclotron and the problem of intense scattering in the slit ***,we present an optical design for a cyclotron-based 50 MeV high-energy proton microbeam system with a micron-sized *** microbeam system,which has an Oxford triplet lens configuration,has relatively small spherical aberrations and is insensitive to changes in the beam divergence angle and momentum *** addition,the energy filtration included in the system can reduce the beam momentum spread from 1 to 0.02%.The effects of lens parasitic aberrations and the lens fringe field on the beam spot resolution are also *** addition,owing to the severe scattering of 50 MeV protons in slit materials,a slit system model based on the Geant4 toolkit enables the quantitative analysis of scattered protons and secondary *** the slit system settings under a 10-micron final beam spot,very few scattered protons can enter the quadrupole lens system and affect the focusing performance of the microbeam system,but the secondary radiation of neutrons and gamma rays generated at the collimation system should be considered for the 50 MeV proton *** data demonstrate that a 50 MeV proton microbeam system with a micron-sized beam spot based on a cyclotron is feasible.

关键词： 50 MeV proton Microbeam Beam optics Aberrations Scattering

Exploring the targets and molecular mechanism of glycyrrhetinic acid against diabetic nephropathy based on network pharmacology and molecular docking

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World Journal of Diabetes 2023年第11期14卷 1672-1692页

作者： Fan-Di Meng Ling Yuan Duo-Jie Xu Meng-Ying Che Shao-Zhang Hou Dou-Dou Lu wen-jing liu Yi Nan Traditional Chinese Medicine College Ningxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina Key Laboratory of Ningxia Ethnomedicine Modernization Ministry of EducationNingxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina College of Pharmacy Ningxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina Ningxia Key Laboratory of Craniocerebral Diseases Ningxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina

BACKGROUND Diabetic nephropathy(DN)stands as the most prevalent chronic microvascular complication of diabetes *** 50%of DN patients progress to end-stage renal disease,posing a substantial health *** To employ network pharmacology and molecular docking methods to predict the mechanism by which glycyrrhetinic acid(GA)treats DN,subsequently validating these predictions through experimental *** The study initially identified GA targets using Pharm Mapper and the TCMSP *** relevant to DN were obtained from the Genecards,OMIM,and TTD *** Venny database facilitated the acquisition of intersecting targets between GA and *** String database was used to construct a protein interaction network,while DAVID database was used to conducted Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis and Gene Ontology(GO)*** docking experiments were performed using Autodock software with selected *** validation was conducted using renal proximal tubular cells(HK-2)as the study subjects.A hyperglycemic environment was simulated using glucose solution,and the effect of GA on cell viability was assessed through the cell counting kit-8 *** cytometry was employed to detect cell cycle and apoptosis,and protein immunoblot(western blot)was used to measure the expression of proteins of the phosphatidylinositol 3-kinase(PI3K)/protein kinase B(AKT)signaling pathway and insulin resistance pathway,including insulin receptor(INSR),PI3K,p-PI3K,AKT,p-AKT,and glycogen synthase kinase-3(GSK3).RESULTS A total of 186 intersecting targets between GA and DN were identified,which were associated with 144 KEGGrelated enrichment pathways,375 GO biological process entries,45 GO cellular component entries,and 112 GO cellular function *** docking demonstrated strong binding of GA to mitogen-activated protein kinase(MAPK)-1,SRC,PIK3R1,HSP90AA1,CASPASE9,HARS,KRAS,and *** vitro experiment

关键词： Network pharmacology Molecular docking Diabetic nephropathy Glycyrrhetinic acid Mechanism of action

Study on the Tissue Culture of Coleus blumei

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Journal of Northeast Agricultural University(English Edition) 2008年第1期15卷 14-17页

作者： wen jing CHE Ye liu Rongmei HU Baozhong College of Life Sciences Northeast Agricultural University Harbin 150030 China

This paper studied on the way of Coleus blumei, the leaf was chosen as explants and was inoculated on 1/2 MS medium with different combinations of 6-benzyladenine （6-BA）, α-naphthaleneacetic acid （NAA） and indole-3-butyric acid （IBA）. The optimal conditions of callus induction from explants were achieved on the medium containing 6-BA （2.0 mg· L^-1） and NAA （1.0 mg· L^-1）. Shoot tips were induced on the medium containing 6-BA （4.0 mg·L^-1） and NAA （0.5 mg·L^-1）. The same media conditions were found suitable for shoot multiplication, we multiplied shoots rooted best on 1/2 MS medium supplemented with IBA （0.1 mg·L^-1）.

关键词： Coleus blumei tissue culture hormone

Syphilitic proctitis mimicking rectal cancer:A case report

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World Journal of Gastrointestinal Pathophysiology 2010年第3期1卷 112-114页

作者： wen-Tao Zhao, jing liu, Yu-Ying Li wen-Tao Zhao Yu-Ying Li Department of colorectal surgery the First Affiliated Hospital Guangzhou University of Traditional Chinese Medicine Guangzhou 510405 Guangdong Province China.

Syphilitic proctitis is a rare disease. It usually presents as proctitis, ulcer and neoplasm but lacks pathognomonic clinical symptoms. It is, therefore, difficult to diagnose and is occasionally treated inappropriately. We report the case of a 51-year-old man who had a hard, ulcerated mass, which occupied the circumference of the rectal wall and which mimicked a rectal tumor. Fortu nately, positive finding from routine toluidine red un heated serum test and treponema pallidum particle ag glutination tests made us reevaluate the patient and led us to suspect syphilitic proctitis. This diagnosis was finally confirmed after successful penicillin G benzathine therapy which made surgery unnecessary.

关键词： Syphilis Rectum Proctitis Rectal cancer Treponema pallidum

Potential application of Nardostachyos Radix et Rhizoma-Rhubarb for the treatment of diabetic kidney disease based on network pharmacology and cell culture experimental verification

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World Journal of Diabetes 2024年第3期15卷 530-551页

作者： Meng-Ying Che Ling Yuan Jiao Min Duo-Jie Xu Dou-Dou Lu wen-jing liu Kai-Li Wang Yan-Yan Wang Yi Nan Key Laboratory of Ningxia Minority Medicine Modernization Ministry of Education Ningxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina College of Pharmacy Ningxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina Traditional Chinese Medicine College Ningxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina School of Clinical Medicine Ningxia Medical UniversityYinchuan 750004Ningxia Hui Autonomous RegionChina Department of Endocrinology Yinchuan Hospital of Traditional Chinese MedicineYinchuan 750004Ningxia Hui Autonomous RegionChina

BACKGROUND Diabetic kidney disease(DKD)is one of the serious complications of diabetes mellitus,and the existing treatments cannot meet the needs of today's *** Chinese medicine has been validated for its efficacy in DKD after many years of clinical ***,the specific mechanism by which it works is still *** the molecular mechanism of the Nardostachyos Radix et Rhizoma-rhubarb drug pair(NRDP)for the treatment of DKD will provide a new way of thinking for the research and development of new *** To investigate the mechanism of the NRDP in DKD by network pharmacology combined with molecular docking,and then verify the initial findings by in vitro *** The Traditional Chinese Medicine Systems Pharmacology(TCMSP)database was used to screen active ingredient targets of *** for DKD were obtained based on the Genecards,OMIM,and TTD *** VENNY 2.1 database was used to obtain DKD and NRDP intersection targets and their Venn diagram,and Cytoscape 3.9.0 was used to build a"drug-component-target-disease"*** String database was used to construct protein interaction *** Encyclopedia of Genes and Genomes(KEGG)enrichment analysis and Gene Ontology analysis were performed based on the DAVID *** selecting the targets and the active ingredients,Autodock software was used to perform molecular *** experimental validation using renal tubular epithelial cells(TCMK-1),we used the Cell Counting Kit-8 assay to detect the effect of NRDP on cell viability,with glucose solution used to mimic a hyperglycemic *** cytometry was used to detect the cell cycle progression and *** blot was used to detect the protein expression of STAT3,p-STAT3,BAX,BCL-2,Caspase9,and *** A total of 10 active ingredients and 85 targets with 111 disease-related signaling pathways were obtained for *** analysis of KEGG pathways was performed to determ

关键词： Nardostachyos Radix et Rhizoma-rhubarb Diabetic kidney disease Molecular docking Network pharmacology Experimental validation