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Underwater acoustic signal denoising model based on secondary variational mode decomposition

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Defence Technology（防务技术） 2023年第10期28卷 87-110页

作者： Hong Yang wen-shuai Shi Guo-hui Li School of Electronic Engineering Xi'an University of Posts and TelecommunicationsXi'anShaanxi710121China

Due to the complexity of marine environment,underwater acoustic signal will be affected by complex background noise during *** acoustic signal denoising is always a difficult problem in underwater acoustic signal *** obtain a better denoising effect,a new denoising method of underwater acoustic signal based on optimized variational mode decomposition by black widow optimization algorithm(BVMD),fluctuation-based dispersion entropy threshold improved by Otsu method(OFDE),cosine similarity stationary threshold(CSST),BVMD,fluctuation-based dispersion entropy(FDE),named BVMD-OFDE-CSST-BVMD-FDE,is *** the first place,decompose the original signal into a series of intrinsic mode functions(IMFs)by ***,distinguish pure IMFs,mixed IMFs and noise IMFs by OFDE and CSST,and reconstruct pure IMFs and mixed IMFs to obtain primary denoised *** the end,decompose primary denoising signal into IMFs by BVMD again,use the FDE value to distinguish noise IMFs and pure IMFs,and reconstruct pure IMFs to obtain the final denoised *** proposed mothod has three advantages:(i)BVMD can adaptively select the decomposition layer and penalty factor of VMD.(ii)FDE and CS are used as double criteria to distinguish noise IMFs from useful IMFs,and Otsu algorithm and CSST algorithm can effectively avoid the error caused by manually selecting thresholds.(iii)Secondary decomposition can make up for the deficiency of primary decomposition and further remove a small amount of *** chaotic signal and real ship signal are *** experiment result shows that the proposed method can effectively *** improves the denoising effect after primary decomposition,and has good practical value.

关键词： Underwater acoustic signal Denoising Variational mode decomposition Secondary decomposition Fluctuation-based dispersion entropy Cosine similarity

Cellular signaling pathways of T cells in giant cell arteritis

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Journal of Geriatric Cardiology 2021年第9期18卷 768-778页

作者： Hai-Yan LI Jun-Nan XU Zong-wen shuai Department of Rheumatology and Immunology the First Affiliated Hospital of Anhui Medical UniversityHefeiChina

Giant cell arteritis(GCA)is a commonly occurring large vacuities characterized by angiopathy of medium and large-sized *** granulomatous formation plays an important role in the pathogenesis of *** of T cell lineages and signaling pathways in GCA have revealed the essential role of T cells in the pathology of GCA.T cells are the dominant population present in GCA ***4+T cell subtypes that are present include Th1,Th2,Th9,Th17,follicular helper T(Tfh)cells,and regulatory T(Treg)***8 T cells can primarily differentiate into cytotoxic CD8+T lymphocytes and Treg *** instrumental part of GCA is the interplay between dendritic cells,macrophages and endothelial cells,which can result in the vascular injury and the characteristics granulomatous infiltrates *** the inflammatory loop of GCA,several signaling pathways have been reported to play an essential role in recruiting,activating and differentiating T cells,including T-cell receptor(TCR)signaling,vascular endothelial growth factor(VEGF)-Jagged-Notch signaling and the Janus kinase and signal transducer and activator of transcription(STAT)pathway(JAK-STAT)*** this review,we have focused on the role of T cells and their potential signaling mechanism(s)that are involved in the pathogenesis of GCA.A better understanding of the role of T cells mediated complicated orchestration during the homeostasis and the changes could possibly favor developments of novel treatment strategies against immunological disorders associated with GCA.

关键词： GCA Cellular signaling pathways of T cells in giant cell arteritis

Hydraulic turbine system identification and predictive control based on GASA-BPNN

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International Journal of Minerals,Metallurgy and Materials 2021年第7期28卷 1240-1247页

作者： Xiao-ping Jiang Zi-ting Wang Hong Zhu wen-shuai Wang School of Mechanical Electrical and Information Engineering China University of Mining and Technology(Beijing)Beijing 100083China

Based on the characteristics of nonlinearity,multi-case,and multi-disturbance,it is difficult to establish an accurate parameter mod-el on the hydraulic turbine system which is limited by the degree of fitting between parametric model and actual model,and the design of con-trol algorithm has a certain degree of *** at the modeling and control problems of hydraulic turbine system,this paper proposes hydraulic turbine system identification and predictive control based on genetic algorithm-simulate anneal and back propagation neural network(GASA-BPNN),and the output value predicted by GASA-BPNN model is fed back to the nonlinear optimizer to output the control *** results show that the output speed of the traditional control system increases greatly and the speed of regulation is slow,while the speed of GASA-BPNN predictive control system increases little and the regulation speed is obviously faster than that of the traditional control *** with the output response of the traditional control of the hydraulic turbine governing system,the neural network predictive control-ler used in this paper has better effect and stronger robustness,solves the problem of poor generalization ability and identification accuracy of the turbine system under variable conditions,and achieves better control effect.

关键词： hydraulic turbine system system identification genetic algorithm simulated annealing algorithm predictive control

Systemic lupus erythematosus with multicentric reticulohistiocytosis: A case report

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World Journal of Clinical Cases 2023年第2期11卷 456-463页

作者： Ping-Ping Liu Zong-wen shuai Li Lian Kang Wang Department of Rheumatology and Immunology Arthritis Research InstituteThe First Affiliated Hospital of Anhui Medical UniversityHefei 230000Anhui ProvinceChina

BACKGROUND Multicentric reticulohistiocytosis(MRH)/systemic lupus erythematosus(SLE) overlap syndrome is an uncommon disease in the clinic and is diagnosed through characteristic clinical manifestations, histopathology, and immunopathology. Here, we report the case of a 30-year-old woman with SLE who developed *** SUMMARY A 30-year-old woman with a history of polyarthritis for the past 12 years had multiple skin nodules on her body for 10 years, including the sacrococcygeal area, dorsum of the hands, interphalangeal joint of the feet and sternoclavicular joint. The histopathology of a biopsy of the distal interphalangeal joint of the hands revealed granulomatous inflammation, fibrous hyperplasia with ground-glass degeneration, inflammatory cell exudation and focal necrosis. The immunohistochemical stains showed positive staining for CD68 and negative staining for S100 and acid-fast staining. The patient was diagnosed with SLE with MRH. Her symptoms were improved after a combined treatment of prednisone, hydroxychloroquine and *** MRH/SLE overlap syndrome is difficult to diagnose and treat. Cyclophosphamide may be an alternative choice for the treatment of MRH.

关键词： Multicentric reticulohistiocytosis Systemic lupus erythematosus Cyclophosphamide Systemic disorder Case report

TiO2 sensitized by red-, green-, blue-emissive carbon dots for enhanced H2 production

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Rare Metals 2019年第5期38卷 404-412页

作者： Dong-Xue Yang Dan Qu Xiang Miao wen-shuai Jiang Li An Yuan-Jing wen Dan-Dan Wu Zai-Cheng Sun Beijing Key Laboratory for Green Catalysis and Separation Department of Chemistry and Chemical Engineering School of Environmental and Energy Beijing University of Technology

Carbon dots(Cdots)with a broad light absorption range could be a potential stable sensitizer for TiO2,which is an excellent ultraviolet(UV)response ***,we systematically investigated the different color emissive Cdots-sensitized TiO2 for H2 ***,all kinds of Cdots enhanced the photocatalytic properties of *** the Cdots-sensitized TiO2 exhibits visible light H2 production due to their absorption in the visible light *** photocurrent and H2 production amount display strong dependence on the light absorption range of *** blue-emissive Cdots endow the weak H2 production rate due to its weak absorption in the visible *** enhanced photocatalytic activities are mainly contributed to the strong light absorbance and high-efficient charge *** light absorption of green-and red-emissive Cdots is another main factor for the high catalytic activities besides charge separation.

关键词： TiO2 Carbon dots Visible light absorption Sensitizer H2 production

Increasing leaching rate of gold cyanide of two-stage calcination generated from refractory ore containing arsenopyrite and pyrrhotite

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Rare Metals 2016年第10期35卷 804-810页

作者： Xiao-E Dang wen-shuai Ke Chen Tang Jun Lv Xue Zhou Cheng-Peng Liu Key Laboratory for Gold and Resources of Shaanxi Xi'an University of Architecture and Technology Jin Rui Mining Technology Development Co. Ltd

For the gold locked within hematite in the two- stage calcination, which leads to a low gold leaching rate, the present work is aiming at pretreating the calcination to selectively dissolve hematite. The calcination was pre- treated by sulfuric acid with cosolvent B. The factors in- fluencing the hematite dissolution rate were studied, and the pretreatment parameters considered were H2SO4 con- tent, B dosage and added time, leaching temperature and time. Simultaneously, mineralogy analysis of the calcination, H2SO4 pretreatment residue and cyanide leaching residue were also carried out. Results indicate that the hematite dissolution rate is quicker, the dissolution tem- perature is lower and the dissolution time is shorter in the role of cosolvent B than without B. At the same time, the gold locked within hematite is effectively released, so the leaching rate of gold cyanide increases about 10 % than that in actual factory production. The results have an actual significance in guiding industrial production.

关键词： Locked gold Hematite Pretreatment Two-stage calcination Cosolvent B

Total synthesis of human urotension-Ⅱ by microwave-assisted solid phase method

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Chinese Chemical Letters 2007年第8期18卷 902-904页

作者： Hui Bin Zhang Yu Shi Chi wen Long Huang shuai Jian Ni Center of Drug Research China Pharmaceutical University Nanjing 210009 China

Human urotension-Ⅱ was synthesized efficiently on Wang resin under microwave irradiation using Fmoc/tBu orthogonal protection strategy. Disulphide bridge was formed on solid phase with the irradiation of microwave, then the whole peptide was cleaved from the resin. The purity of crude peptide cyclized under microwave irradiation was higher than that under room temperature.

关键词： Human urotension-Ⅱ Microwave irradiation Solid phase Disulphide bridge

A Novel Hydroperoxyl Substituted Cembranolide Diterpene from Marine Soft Coral Lobophytum crassum

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Chinese Chemical Letters 2005年第11期16卷 1489-1491页

作者： shuai wen YIN Yan Ping SHI Xiao Ming LI Bin Gui WANG Key Laboratory of Experimental Marine Biology Institute of Oceanology Chinese Academy of Sciences Qingdao 266071 Key Laboratory for Natural Medicine of Gansu Province Lanzhou Institute of Chemical Physics Chinese Academy of Sciences Lanzhou 730000 Graduate School of the Chinese Academy of Sciences Beijing 100039

A new cembranolide diterpene with a hydroperoxyl substitution was isolated from the marine soft coral Lobophytum crassum. The structure was elucidated on the basis of chemical and spectral methods.

关键词： Lobophytum crassum 2-hydroperoxysarcophine cembranolide diterpene.

Deciphering the role of FSCN family genes in cancer:a pan-cancer bioinformatics study

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Medical Data Mining 2024年第4期7卷 10-18页

作者： wen-shuai Zhang Dan-Yang Ren Xin Li Department of Pathology Tianjin Cancer Hospital Airport HospitalTianjin 300308China National Clinical Research Center for Cancer Tianjin Medical University Cancer Institute and HospitalKey Laboratory of Cancer Prevention and TherapyTianjin’s Clinical Research Center for CancerTianjin 300060China

Background:The Fascin(FSCN)family,comprising actin-bundling proteins,plays vital roles in cytoskeletal reorganization and cell ***1,FSCN2,and FSCN3 are implicated in cancer progression through cell motility,invasion,and ***,their specific contributions across different cancer types remain ***:We conducted a pan-cancer bioinformatics analysis of FSCN genes using data from The Cancer Genome *** included differential expression patterns,copy number variations(CNVs),mutations,methylation status,and correlations with tumor mutational burden,microsatellite instability,and immune checkpoint molecule *** expression was analyzed using DESeq2,while CNV and mutation analyses utilized GISTIC2.0 and *** data were assessed using the Illumina Human Methylation 450K ***:FSCN1 and FSCN2 showed significant differential expression in multiple cancers,often correlating with poor ***3 exhibited less variability but a protective role in certain *** analysis indicated frequent gene gains in FSCN genes,correlating with increased ***3 had a higher mutation rate,suggesting genetic *** analysis showed hypomethylation of FSCN1 and FSCN2 in tumors compared to normal tissues,whereas FSCN3 had minor *** associations were found between FSCN gene expression and tumor mutational burden,microsatellite instability,and immune checkpoint molecules,suggesting their involvement in tumor immunogenicity and the immune ***:This pan-cancer analysis highlights the multifaceted roles of FSCN genes in cancer biology,emphasizing their potential as biomarkers and therapeutic ***1 and FSCN2 are associated with poor prognosis and aggressive phenotypes,while FSCN3 shows protective roles in specific *** findings offer new avenues for cancer diagnosis and treatment,particularly in personalized *** studie

关键词： Fascin family pan-cancer analysis gene expression copy number variation tumor mutational burden