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GIS Based Aroma Characteristic for Regional Distribution of Tobacco Using Kriging Interpolation Method Set in Henan Province of China

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Journal of Northeast Agricultural University(English Edition) 2018年第4期25卷 71-78页

作者： Xu Yue-qi wang Peng-ze Tao Tao Dang Xia Li Yan-zhou Wei hui-qin Ma wen-hui Yang Nan Pingdingshan Branch of Henan Province Tobacco Company Pingdingshan 467000HenanChina Tianchang International Tobacco Co. Ltd.Tianchang Redrying FactoryXuchang 461000HenanChina College of Tobacco Science Henan Agricultural UniversityZhcngzhou 450002China Tianchang International Tobacco Co. Ltd.Xuchang 461000HcnanChina

To study the regional distribution features of aroma characteristics, the regional distribution maps of aroma characteristics of 225 tobacco leaf samples from Henan Province were drawn by Kriging interpolation method in ArcGIS. The results showed that:(1) the aroma quality of flue-cured tobacco from Henan Province tobacco-growing areas ranged from better to slightly better and aroma quantity ranged from just a little to much. The ability of diffusiveness expressed slight to a little strong and the raw green odour, immature odour and ligneous odour were tiny;(2) there were significant differences between the aroma quality and scorched odour and no statistical differences among the aroma quantity, diffusiveness, raw green odour, ligneous odour and immature odour from different counties;(3) there were trends that scale of aroma quality increased from southwest to both north and east, aroma quantity showed a patchy distribution in space, diffusiveness decreased from east to west, scorched odour increased from west to both north and south, ligneous odour increased from north to south and green odour increased from south to north.

关键词： tobacco leaf sensory evaluation aroma characteristic regional distribution characteristic

Pathogens of first-episode pulmonary infection in 141 children with chronic granulomatous disease

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Chinese Medical Journal 2024年第4期137卷 502-504页

作者： hui Liu Shunying Zhao Haiming Yang Jinrong Liu hui Xu Xiaolei Tang Yuelin Shen Xiaoyan Zhang Xiaohui wen Yuhong Zhao Ping Chu huimin Li Department of Second Respiratory Medicine National Clinical Research Center for Respiratory DiseasesBeijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijing 100045China Office of Scientific Research Beijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijing 100045China

To the Editor:Chronic granulomatous disease(CGD)is an inherited primary immunodeficiency disease characterized by recurrent life-threatening bacterial or fungal infection and tissue granuloma formation.^([1])Pulmonary infection is the most frequent manifestation,affecting nearly 80%of patients,[2]and remains the major cause of morbidity and mortality in patients with *** of the pathogenic microorganisms responsible for first-episode pulmonary infection provide information on the spectrum of infection in patients with CGD,help guide the empirical choice of antibiotics or antifungal therapy,and contribute to the early identification and management of *** is the commonest causative agent of pulmonary infection,but the distribution of other pathogens varies among countries.^([2–5])Few studies have investigated the etiology of pulmonary infection in CGD in a large cohort in China.

关键词： granuloma infection mortality

Plexin domain-containing 1 may be a biomarker of poor prognosis in hepatocellular carcinoma patients,may mediate immune evasion

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 2091-2112页

作者： Ming-Yue Tang Xue Shen Run-Sheng Yuan hui-Yuan Li Xin-Wei Li Yi-Ming Jing Yue Zhang Hong-Hong Shen Zi-Shu wang Lei Zhou Yun-Chuan Yang He-Xin wen Fang Su Department of Medical Oncology The First Affiliated Hospital of Bengbu Medical CollegeBengbu 233000Anhui ProvinceChina Otolaryngology and Head and Neck Surgery The First Affiliated Hospital of Bengbu Medical CollegeBengbu 233000Anhui ProvinceChina Department of Neurology The First Affiliated Hospital of Bengbu Medical CollegeBengbu 233000Anhui ProvinceChina Department of Hepatobiliary Surgery The First Affiliated Hospital of Bengbu Medical CollegeBengbu 233000Anhui ProvinceChina Department of Gastrointestinal Surgery The First Affiliated Hospital of Bengbu Medical CollegeBengbu 233000Anhui ProvinceChina

BACKGROUND For the first time,we investigated the oncological role of plexin domain-containing 1(PLXDC1),also known as tumor endothelial marker 7(TEM7),in hepatocellular carcinoma(HCC).AIM To investigate the oncological profile of PLXDC1 in *** Based on The Cancer Genome Atlas database,we analyzed the expression of PLXDC1 in *** immunohistochemistry,quantitative real-time polymerase chain reaction(qRT-PCR),and Western blotting,we validated our *** prognostic value of PLXDC1 in HCC was analyzed by assessing its correlation with clinicopathological features,such as patient survival,methylation level,tumor immune microenvironment features,and immune cell surface checkpoint ***,to assess the immune evasion potential of PLXDC1 in HCC,we used the tumor immune dysfunction and exclusion(TIDE)website and immunohistochemical staining *** Based on immunohistochemistry,qRT-PCR,and Western blot assays,overexpression of PLXDC1 in HCC was associated with poor *** and multivariate Cox analyses indicated that PLXDC1 might be an independent prognostic *** HCC patients with high methylation levels,the prognosis was worse than in patients with low methylation *** enrichment analysis of HCC tissues indicated that genes upregulated in the high-PLXDC1 subgroup were enriched in mesenchymal and immune activation signaling,and TIDE assessment showed that the risk of immune evasion was significantly higher in the high-PLXDC1 subgroup compared to the low-PLXDC1 *** high-risk group had a significantly lower immune evasion rate as well as a poor prognosis,and PLXDC1-related risk scores were also associated with a poor *** As a result of this study analyzing PLXDC1 from multiple biological perspectives,it was revealed that it is a biomarker of poor prognosis for HCC patients,and that it plays a role in determining immune evasion status.

关键词： Plexin domain-containing 1 Biomarker Immune evasion Prognosis Immunotherapy Hepatocellular carcinoma

Fabrication of RGO/Cu composites based on electrostatic adsorption

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Transactions of Nonferrous Metals Society of China 2020年第4期30卷 982-991页

作者： wen-min ZHAO Rui BAO Jian-hong YI Xiang-hui HOU Dong FANG Chun-xuan LIU Faculty of Materials Science and Engineering Kunming University of Science and TechnologyKunming 650093China Key Laboratory of Advanced Materials of Yunnan Province Kunming 650093China Faculty of Engineering University of NottinghamUniversity ParkNottingham NG72RDUK Hunan Xiangtou Goldsky Technology Group Co. Ltd.Changsha 410012China

To address the issues of reduced graphene oxide(RGO) dispersion in copper(Cu) matrix and interface bonding between RGO and Cu, an electrostatic adsorption method with interface transition phase design was employed to prepare the RGO/Cu based composites. Cu-Ti alloy powder was employed to improve the combination by forming carbides at the RGO-Cu interface. It was noted that the mechanical property of 0.3 wt.%RGO/Cu-Ti composite was increased by 60% compared with that of the matrix. Strengthening mechanism analysis suggested that the enhancement of the mechanical property was ascribed to the load transfer and second phase strengthening which were from the improved dispersion of RGO and the in-situ formed titanium carbide phase.

关键词： graphene oxide(GO) electrostatic adsorption Cu?Ti in-situ TixCy mechanical property

MRI Optimization Scanning of Cervical Spine with Titanium Alloy Internal Fixation

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MRI Optimization Scanning of Cervical Spine with Titanium Al...

普朗斑岩型铜矿床成矿元素多重分形特征及其矿化强度指示

2009中华医学会影像技术分会第十七次全国学术大会

作者： ZHANG Yan QU wen XU hui ZHAO Qiang ZHOU Guangjin 北京大学第三医院

Objective:To discuss how to optimize MRI scanning parameters of cervical spine with titanium alloy internal fixation,to reduce susceptibility artifacts

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吉林大学学报（地球科学版） 2021年第4期51卷 1054-1063页

作者：万丽刘慧曾祥健广州大学数学与信息科学学院广州510006 数学与交叉科学广东普通高校重点实验室(广州大学) 广州510006

成矿元素品位的变化受控于长期地质作用过程,具有较强的非线性特征,定量刻画其变化特征有助于深入理解成矿过程,并为找矿预测提供理论依据。运用多重分形去趋势移动均值(MFDMA)法,分析云南普朗斑岩型铜矿床4号勘探线钻孔Cu元素品位的多... 详细信息

成矿元素品位的变化受控于长期地质作用过程,具有较强的非线性特征,定量刻画其变化特征有助于深入理解成矿过程,并为找矿预测提供理论依据。运用多重分形去趋势移动均值(MFDMA)法,分析云南普朗斑岩型铜矿床4号勘探线钻孔Cu元素品位的多重分形特征及其对矿化强度的指示意义。结果显示:所有钻孔Cu元素品位具有多重分形特征,且不同矿化等级的元素分布存在局部奇异性差异,多重分形强度随矿化强度等级减弱而增加;这些特征指示在钾硅化带—带内侧强矿化钻孔的高品位相对聚集,而带外侧角岩化—青磐岩化带的高品位相对分散;通过数据随机重排技术推测Cu品位多重分形结构奇异性差异是由其分布概率密度和长相关性共同作用引起,后者的作用贡献大于前者。

关键词：多重分形去趋势移动均值(MFDMA)法多重分形标度奇异性成矿元素矿化强度普朗斑岩型铜矿床

标准火灾后钢管RPC柱抗近距离爆炸荷载的试验研究

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工程力学 2017年第1期34卷 180-191页

作者：陈万祥郭志昆邹慧辉张涛解放军理工大学爆炸冲击防灾减灾国家重点实验室南京210007

利用野外抗爆试验场对4根大比例标准火灾后的钢管活性粉末混凝土(Reactive Powder Concrete Filled Steel Tubular,简称钢管RPC)柱进行了抗近距离爆炸试验研究,探讨了恒定轴向力条件下比例距离和受火时间对柱动力响应和破坏形态的影响... 详细信息

利用野外抗爆试验场对4根大比例标准火灾后的钢管活性粉末混凝土(Reactive Powder Concrete Filled Steel Tubular,简称钢管RPC)柱进行了抗近距离爆炸试验研究,探讨了恒定轴向力条件下比例距离和受火时间对柱动力响应和破坏形态的影响。结果表明:标准火灾下钢管仍可以有效约束RPC芯柱,限制了RPC的高温爆裂,表现出良好的抗火性能。爆炸作用下火灾后钢管RPC柱的相对位移均超过2.0%,均达到了其屈服状态。当比例距离由0.58 m/kg1/3减小到0.48 m/kg1/3时,钢管RPC柱出现由弯曲变形过渡到弯剪变形的趋势。随着受火时间增加,钢管RPC柱跨中出现明显的塑性变形,最大位移和残余位移均显著增大,发生典型的弯曲破坏。与比例距离相比,钢管RPC柱的抗爆能力对受火时间更为敏感。采用LS-DYNA软件对试验结果进行了数值模拟,模拟结果与试验结果吻合较好。

关键词：钢管RPC 抗爆试验火灾后比例距离动力响应

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丹参酮类抗肿瘤作用与机制研究进展

中国药理学通报 2014年第8期30卷 1041-1044页

作者：郝文慧赵文文陈修平中药质量研究国家重点实验室澳门大学中华医药研究院澳门大学中国澳门特别行政区

丹参酮类是从传统中药丹参(Salvia miltiorrhiza Bunge)及其同属植物中分离到的一大类脂溶性天然产物,包括丹参酮ⅡA、隐丹参酮、丹参酮Ⅰ、二氢丹参酮Ⅰ等多种成分。丹参酮类与丹酚酸类均被证实是丹参的主要特征性成分和活性成分,具有... 详细信息

丹参酮类是从传统中药丹参(Salvia miltiorrhiza Bunge)及其同属植物中分离到的一大类脂溶性天然产物,包括丹参酮ⅡA、隐丹参酮、丹参酮Ⅰ、二氢丹参酮Ⅰ等多种成分。丹参酮类与丹酚酸类均被证实是丹参的主要特征性成分和活性成分,具有较明显的心脑血管保护活性。近年来研究发现,丹参酮类在体内外有较好的抗肿瘤活性。该文就丹参酮类化合物尤其是丹参酮ⅡA的抗肿瘤作用与机制的最新研究进展作一综述,以期为该类化合物的研究和开发提供参考。

关键词：隐丹参酮肿瘤作用与机制进展

Role of saliva proteinase 3 in dental caries

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International Journal of Oral Science 2015年第3期7卷 174-178页

作者： Teng-Yu Yang wen-Jie Zhou Yue Du Song-Tao Wu wen-wen Yuan Yu Yu Lin Su Yang Luo Jie-Hua Zhang wan-Lu Lu Xiao-Qian wang Jiao Chen Yun Feng Xue-Dong Zhou Ping Zhang State Key Laboratory of Oral Diseases West China Hospital of Stomatology Sichuan University

Salivary analysis can be used to assess the severity of caries. Of the known salivary proteins, a paucity of information exists concerning the role of proteinase 3（PR3）, a serine protease of the chymotrypsin family, in dental caries. Whole, unstimulated saliva was collected from children with varying degrees of active caries and tested using a Human Protease Array Kit and an enzyme-linked immunosorbent assay.A significantly decreased concentration of salivary PR3 was noted with increasing severity of dental caries（P,0.01）; a positive correlation（r50.87; P,0.01; Pearson’s correlation analysis） was also observed between salivary p H and PR3 concentration. In an antibacterial test,a PR3 concentration of 250 ng？m L21 or higher significantly inhibited Streptococcus mutans UA159 growth after 12 h of incubation（P,0.05）. These studies indicate that PR3 is a salivary factor associated with the severity of dental caries, as suggested by the negative relationship between salivary PR3 concentration and the severity of caries as well as the susceptibility of S. mutans to PR3.

关键词： salivary caries proteinase 3 pH Streptococcus mutans