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Calcitonin gene-related peptide and traumatic brain injury

Neural Regeneration Research 2019年第4期14卷 736-736页

作者： saul Almeida da silva Almir F.de Andrade Robson Luis Oliveira de Amorim wellingson s.paiva Division of Neurological surgery Hospital das Clinicas HCMFUSP Universidade de Sao Paulo

Dear editor,It is with great interest that we read the article“Relationship of calcitonin gene-related peptide with disease progression and prognosis of patients with severe traumatic brain injury”(Chen et al.,2018).In this study,the authors evaluated 121 patients who were divided into mild/moderate traumatic brain injury(TBI)(n=61),severe TBI(n=35)and control(n=25)groups,and measured serum levels of calcitonin gene-related peptide(CGRP)and serum endothelin-1(ET-1).They found that low levels of CGRP and high levels of ET-1 were associated with high mortality at 6 *** of morphological abnormalities on CT scans is very important for evaluating patients with TBI because different diagnoses are made based on different imaging findings(Maas et al.,2005).

关键词： Calcitonin gene-related peptide traumatic brain injury

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Is transcranial magnetic stimulation useful in posttraumatic disorders?

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Neural Regeneration Research 2015年第9期10卷 1528-1528页

作者： wellingson silva paiva Iuri santana Neville Felipe Fregni Manoel Jacobsen Teixeira Neurotrauma Unit Division of Neurosurgery at University of S?o Paulo Medical School Research Center at Hospital samaritano Laboratory of Neuromodulation Spaulding Rehabilitation Hospital at Harvard Medical School

Dear editor, We have read with great interest the recent paper by Herrold et al. （2014） published in Neural Regeneration Research. There is evidence that approximately 20-90% of patients with mild traumatic brain injury develop posttraumatic symptoms, and 40% of these patients have persistent symptoms after trauma （Bazarian et al., 1999; Koski et al., 2015）. Therefore, mild traumatic brain injury becomes an important cause of temporary disability. Indeed, posttraumatic disorders have a significant epidemiological relevance, even though it is still undervalued in most of the trauma centers （Bazarian et al., 1999） and there is no specific treatment method （Koski et al., 2015）. Recently, many neurological and posttraumatic stress disorders had been treated with noninvasive brain stimulation （Boggio et al., 2010; Fox et al., 2012）.

关键词： TMs Is transcranial magnetic stimulation useful in posttraumatic disorders

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