Calcitonin gene-related peptide and traumatic brain injury

作     者：Saul Almeida da Silva Almir F.de Andrade Robson Luis Oliveira de Amorim Wellingson S.Paiva 

作者机构：Division of Neurological Surgery Hospital das Clinicas HCMFUSP Universidade de Sao Paulo 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2019年第14卷第4期

页      面：736-736页

核心收录：

学科分类：10[医学] 

主　　题：Calcitonin gene-related peptide traumatic brain injury 

摘      要：Dear editor,It is with great interest that we read the article“Relationship of calcitonin gene-related peptide with disease progression and prognosis of patients with severe traumatic brain injury(Chen et al.,2018).In this study,the authors evaluated 121 patients who were divided into mild/moderate traumatic brain injury(TBI)(n=61),severe TBI(n=35)and control(n=25)groups,and measured serum levels of calcitonin gene-related peptide(CGRP)and serum endothelin-1(ET-1).They found that low levels of CGRP and high levels of ET-1 were associated with high mortality at 6 *** of morphological abnormalities on CT scans is very important for evaluating patients with TBI because different diagnoses are made based on different imaging findings(Maas et al.,2005).