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Relationship between dietary niacin intake and erectile dysfunction:a population-based study

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Asian Journal of Andrology 2024年第4期26卷 382-388页

作者： wei-long lin Cheng Zheng Hao-Xu Wang wei Zhang Ming-En lin Department of Urology The First Affiliated Hospital of Shantou University Medical CollegeMedical College of Shantou UniversityShantou 515041China The Second School of Clinical Medicine Southern Medical UniversityGuangzhou 510260China.

Existing research on the precise link between dietary niacin intake and erectile dysfunction(ED)is ***,this study aimed to investigate the potential association between dietary niacin intake and the risk of *** logistic regression and restricted cubic splines(RCSs)were used to examine the relationship between dietary niacin intake and *** interaction analysis was performed to assess the impact of different subgroups on the study *** addition,1:1 propensity score matching(PSM)was employed to adjust for potential confounding factors,ensuring the reliability of the *** analyzed data were collected from the 2001–2004 National Health and Nutrition Examination Survey(NHANES)in the *** study encompassed 3184 adults,among whom 863 participants were identified as having *** adjustments for potential confounders,the findings revealed that higher niacin intake,specifically in the highest tertile,was associated with a decreased risk of ED compared to that in the lowest tertile,showing an odds ratio(OR)of 0.56(95%confidence interval[CI]:0.37–0.85).Analysis of dose–response curves illustrated a negative correlation between dietary niacin intake and the risk of *** and interaction analyses fortified the consistency of these ***,PSM corroborated the validity of the *** study suggests an inverse association between dietary niacin intake and the risk of ***,establishing a cause-and-effect relationship remains elusive,and defining the safe threshold of niacin intake to prevent ED requires further investigation.

关键词： dietary niacin erectile dysfunction National Health and Nutrition Examination Survey propensity score matching

Infiltration by monocytes of the central nervous system and its role in multiple sclerosis: reflections on therapeutic strategies

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Neural Regeneration Research 2025年第3期20卷 779-793页

作者： Guangyong Zhang Qing Yao Chubing long Pengcheng Yi Jiali Song Luojia Wu wei Wan Xiuqin Rao Yue lin Gen wei Jun Ying Fuzhou Hua Department of Anesthesiology the Second Affiliated Hospital of Nanchang UniversityNanchangJiangxi ProvinceChina Key Laboratory of Anesthesiology of Jiangxi Province NanchangJiangxi ProvinceChina

Mononuclear macrophage infiltration in the central nervous system is a prominent feature of neuroinflammation. Recent studies on the pathogenesis and progression of multiple sclerosis have highlighted the multiple roles of mononuclear macrophages in the neuroinflammatory process. Monocytes play a significant role in neuroinflammation, and managing neuroinflammation by manipulating peripheral monocytes stands out as an effective strategy for the treatment of multiple sclerosis, leading to improved patient outcomes. This review outlines the steps involved in the entry of myeloid monocytes into the central nervous system that are targets for effective intervention: the activation of bone marrow hematopoiesis, migration of monocytes in the blood, and penetration of the blood–brain barrier by monocytes. Finally, we summarize the different monocyte subpopulations and their effects on the central nervous system based on phenotypic differences. As activated microglia resemble monocyte-derived macrophages, it is important to accurately identify the role of monocyte-derived macrophages in disease. Depending on the roles played by monocyte-derived macrophages at different stages of the disease, several of these processes can be interrupted to limit neuroinflammation and improve patient prognosis. Here, we discuss possible strategies to target monocytes in neurological diseases, focusing on three key aspects of monocyte infiltration into the central nervous system, to provide new ideas for the treatment of neurodegenerative diseases.

关键词： blood–brain barrier macrophages monocytes multiple sclerosis neuroinflammation review therapy

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基于PLC技术的海上自动化动力系统研究

舰船科学技术 2019年第14期41卷 106-108页

作者：龙威林天津现代职业技术学院

传统海上船舶动力系统在动力输出与传送上存在动力损耗过大、动力值计算输出准确性差的问题。针对问题产生根源结合PLC技术,提出基于PLC技术的海上自动化动力系统研究。通过改进传统动力运算硬件,创建PLC动力综合采集平台,实现对海上舰... 详细信息

传统海上船舶动力系统在动力输出与传送上存在动力损耗过大、动力值计算输出准确性差的问题。针对问题产生根源结合PLC技术,提出基于PLC技术的海上自动化动力系统研究。通过改进传统动力运算硬件,创建PLC动力综合采集平台,实现对海上舰船动力相关参数的综合收集分析处理;其次,引入多动力遗传数据算法对动力参数进行遗传自动逻辑量运算,求得自动化最优动力参数;最后,通过仿真实验证明,提出设计的PLC技术的海上自动化动力系统,具有动力参数计算准确、动力自动化程度高的特点,能够从根本上解决传统海上动力系统存在的问题。

关键词： PLC技术海上自动化动力系统

Aerodynamic Optimization and Flow Mechanism for a Compressor Cascade at Low Reynolds Number

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Journal of Thermal Science 2025年第1期34卷 92-109页

作者： LI lin ZHANG Jianshe CHEN Caiyan TAN wei ZHANG Yanfeng Key Laboratory of Light-Duty Gas-Turbine Institute of Engineering ThermophysicsChinese Academy of Sciences University of Chinese Academy of Sciences National Key Laboratory of Science and Technology on Advanced Light-duty Gas-turbine

Low-Reynolds-number effect is an important factor affecting the performance of compressors and other main components of high-altitude long-endurance unmanned aerial *** improve the flow condition and reduce flow loss under the condition of high altitude and low Reynolds number(Re),this paper proposes an optimization process based on a surrogate model,which combines the class-shape transformation method(CST),the Latin hypercube sampling(LHS) method,the light gradient-boosting machine algorithm(LightGBM),and a genetic algorithm(GA) to optimize a high-subsonic compressor *** surrogate model is verified to be accurate and can be used in the optimization *** accuracy of the GA is higher than the other algorithms under common test *** optimization results are verified by numerical simulation,and the flow differences before and after optimization are compared,especially the flow within the boundary *** changing the blade shape,the optimization process adjusts the loading distribution to delay the transition of the optimized blade on the suction surface,which changes the turbulent reattachment in the laminar separation bubble(LSB) into laminar ***,the mixing loss induced by the turbulent reattachment of the LSB and the wake loss of turbulent separation at the trailing edge are significantly reduced,and the performance of the compressor profile is finally *** addition,turbulent separation of the optimized profile is delayed reducing the range of the wake region on the suction *** this optimization process,the reduction of total pressure loss coefficient at Re of 2.5×10～5,3.5×10～5,and 4.5×10～5 are 16.32%,20.76%,and 22.16%,respectively.

关键词： Reynolds number

Effect of Mechanical Stress in Combination with Verapamil on Levels of Aggrecan and ADAMTS-5 mRNAs and Proteins in Human Osteoarthritic Chondrocyte/Agarose Constructs

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Chinese Medical Journal 2018年第18期131卷 2229-2231页

作者： Dan Luo Yan Shen Jian-Qiang Lyu Yong-Qian Fan Dong-Hui Huang wei-long lin Hai-Min Shen Hu-Ji Xu Jian-long Guan Department of Rheumatology Huadong Hospital Fudan University Shanghai 200040 China Key Laboratory of Exercise and Health Sciences of Ministry of Education School of Kinesiology Shanghai University of Sport Shanghai 200438 China Department of Orthopedic Surgery Huadong Hospital Fudan University Shanghai 200040 China Department of Rheumatology Changzheng Hospital Second Military Medical University Shanghai 200003 China Department of Rheumatology Shanghai Key Laboratory of Clinical Geriatric Medicine Huadong Hospital Fudan University Shanghai 200040 China

To the Editor： Osteoarthritis （OA） has the highest prevalence and economic impact among arthritic maladies and is the most common cause of long-term disability among individuals over 65 years of age. OA is characterized by the degeneration of articular cartilage and the loss of cartilage matrix in affected joints. It is widely accepted that an imbalance between the biosynthesis and the degradation of extracellular matrix （ECM） occurs in OA cartilage.

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教学型智能移动机器人在“走迷宫”竞赛中的应用

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天津职业院校联合学报 2015年第8期17卷 55-61页

作者：龙威林天津现代职业技术学院天津300350

将教学型智能移动机器人成功的应用在电脑鼠走迷宫竞赛当中,与实际教学联系的更加紧密。对电脑鼠走迷宫竞赛中的实际问题,如运动姿态的控制进行了研究,并对几种经典的路径规划和优化算法进行了研究。本文研制的教学型智能移动机器人不... 详细信息

将教学型智能移动机器人成功的应用在电脑鼠走迷宫竞赛当中,与实际教学联系的更加紧密。对电脑鼠走迷宫竞赛中的实际问题,如运动姿态的控制进行了研究,并对几种经典的路径规划和优化算法进行了研究。本文研制的教学型智能移动机器人不仅具有性能稳定、实时性好等特点,此外,在设计上考虑全面,结合了多学科的知识技术,能够实现模块化扩展,也尽可能的降低了成本,便于高校相关专业学生实践学习和竞赛培训使用。

关键词：教学型智能移动机器人嵌入式硬件平台嵌入式软件平台电脑鼠走迷宫竞赛路径规划

A Flexible Smart Healthcare Platform Conjugated with Artificial Epidermis Assembled by Three‑Dimensionally Conductive MOF Network for Gas and Pressure Sensing

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Nano-Micro Letters 2025年第2期17卷 601-620页

作者： Qingqing Zhou Qihang Ding Zixun Geng Chencheng Hu long Yang Zitong Kan Biao Dong Miae Won Hongwei Song lin Xu Jong Seung Kim State Key Laboratory of Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityChangchun 130012People’s Republic of China Department of Chemistry Korea UniversitySeoul 02841Republic of Korea TheranoChem Incorporation Seoul 02856Republic of Korea

The rising flexible and intelligent electronics greatly facilitate the noninvasive and timely tracking of physiological information in telemedicine *** building bionic-sensitive moieties is vital for designing efficient electronic skin with advanced cognitive functionalities to pluralistically capture external ***,realistic mimesis,both in the skin’s three-dimensional interlocked hierarchical structures and synchronous encoding multistimuli information capacities,remains a challenging yet vital need for simplifying the design of flexible logic ***,we construct an artificial epidermal device by in situ growing Cu_(3)(HHTP)_(2) particles onto the hollow spherical Ti_(3)C_(2)T_(x) surface,aiming to concurrently emulate the spinous and granular layers of the skin’s *** bionic Ti_(3)C_(2)T_(x)@Cu_(3)(HHTP)_(2) exhibits independent NO_(2) and pressure response,as well as novel functionalities such as acoustic signature perception and Morse code-encrypted message ***,a wearable alarming system with a mobile application terminal is self-developed by integrating the bimodular senor into flexible printed *** system can assess risk factors related with asthmatic,such as stimulation of external NO_(2) gas,abnormal expiratory behavior and exertion degrees of fingers,achieving a recognition accuracy of 97.6%as assisted by a machine learning *** work provides a feasible routine to develop intelligent multifunctional healthcare equipment for burgeoning transformative telemedicine diagnosis.

关键词： Ti_(3)C_(2)T_(x)@Cu_(3)(HHTP)_(2)composites NO_(2)/pressure flexible sensors Health-monitoring Machine learning

新时代人工智能对职业教育专业格局的影响分析

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天津职业院校联合学报 2019年第8期21卷 3-6页

作者：龙威林天津现代职业技术学院

人类社会生活的各个层面都已经感受到人工智能的存在和影响.产品质量和生产效率因人工智能的产品和应用得到了有效的提升.人工智能将从事冗余、机械工作的从业人员解放出来,对各行各业都产生了影响,而教育首当其冲.文中分析了人工智能... 详细信息

人类社会生活的各个层面都已经感受到人工智能的存在和影响.产品质量和生产效率因人工智能的产品和应用得到了有效的提升.人工智能将从事冗余、机械工作的从业人员解放出来,对各行各业都产生了影响,而教育首当其冲.文中分析了人工智能发展对专业岗位的影响,分析了其对职业教育专业结构的影响,并对人工智能的专业构建提出了建设性意见.

关键词：人工智能岗位职业教育专业建设

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智慧农业环境信息采集系统设计

天津职业院校联合学报 2020年第11期22卷 107-113页

作者：龙威林高艺天津现代职业技术学院天津300350 南开大学电子信息与光学工程学院天津300071

随着建立在无线传感器网络基础上的大范围数据采集技术的迅速发展,智慧农业环境信息采集系统能够做到全天候、不间断的监控农田、采集各项土壤信息,从而为所监测农田的田间管理和生产规划提供科学有效的数据参考。本系统建立了分层式的... 详细信息

随着建立在无线传感器网络基础上的大范围数据采集技术的迅速发展,智慧农业环境信息采集系统能够做到全天候、不间断的监控农田、采集各项土壤信息,从而为所监测农田的田间管理和生产规划提供科学有效的数据参考。本系统建立了分层式的网络拓扑结构,上层结构为自组织网络结构,下层则采用星型的网络结构。此外,提出了节点能量供给的改进方案——通过太阳能获取能量的能量供给系统。通过一系列实践证明,本系统具有扩展性好、可靠性高的优点,有较大的实用价值和推广价值。

关键词：智慧农业无线传感器网络太阳能 μC/OS-II