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Relationship between preoperative psychological stress and shortterm prognosis in elderly patients with femoral neck fracture

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World Journal of Psychiatry 2024年第6期14卷 838-847页

作者： Wen-Hui Fu Zhi-Long Hu Yuan-Jun liao Ri-Jiang Chen Jian-Bin Qiu Wu-Tang Que Wan-Tao Wang wei-hua li wei-Bin Lan Department of Orthopedics Longyan First Affiliated Hospital of Fujian Medical UniversityLongyan 361000Fujian ProvinceChina

BACKGROUND Older adults are at high risk of femoral neck fractures(FNFs).Elderly patients face and adapt to significant psychological burdens,resulting in different degrees of psychological stress *** hip replacement is the preferred treatment for FNF in elderly patients;however,some patients have poor postoperative prognoses,and the underlying mechanism is *** speculated that the postoperative prognosis of elderly patients with FNF may be related to preoperative psychological *** To explore the relationship between preoperative psychological stress and the short-term prognosis of elderly patients with *** In this retrospective analysis,the baseline data,preoperative 90-item Symptom Checklist score,and Harris score within 6 months of surgery of 120 elderly patients with FNF who underwent total hip arthroplasty were *** analyzed the indicators of poor short-term postoperative prognosis and the ability of the indicators to predict poor prognosis and compared the correlation between the indicators and the Harris *** Anxiety,depression,garden classification of FNF,cause of fracture,FNF reduction quality,and length of hospital stay were independent influencing factors for poor short-term postoperative prognoses in elderly patients with FNF(Plity reduction,and length of hospital stay were the highest at 0.880,0.783,and 0.761,***,depression,and somatization scores correlated moderately with Harris scores(r=-0.523,-0.625,and-0.554;all P<0.001).CONCLUSION Preoperative anxiety,depression,and somatization are correlated with poor short-term prognosis in elderly patients with FNF and warrant consid

关键词： Psychological stress Old age Femoral neck fracture Hip replacement Short-term prognosis Correlation

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有限域上的正规元与不可约多项式

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数学学报（中文版） 2024年第4期67卷 624-633页

作者：曹炜李卫华徐碧云闽南师范大学数学与统计学院漳州363000 福建省粒计算及其应用重点实验室漳州363000 宁波大学数学与统计学院宁波315211

设F_(q)为q阶有限域,F_(q)^(n)为F_(q)的n次扩域.设α∈F_(q)^(n),若{α,α^(q),...,α^(q^(n-1))}构成F_(q)^(n)/F_(q)的一组基,称α为F_(q)^(n)/F_(q)的正规元.正规元可用来加速有限域上的算术运算,因而在编码和密码中具有重要应用.正规元的极小多项式一定是非零迹的不可约多项式,但反之未必成立.本文利用线性化多项式给出了关于该问题的一组充分必要条件,推广了已知结论.

关键词：有限域正规元线性化多项式不可约多项式

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Self-assembled Conformations of a Core-shell Comb-like Chain with Adjustable Architectural Parameters

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Chinese Journal of Polymer Science 2023年第9期41卷 1439-1446,I0008页

作者： huan-li Qi Heng-wei Zhou Chao Duan wei-hua li Ming-Ming Ding Xinjiang Laboratory of Phase Transitions and Microstructures in Condensed Matter Physics College of Physical Science and TechnologyYili Normal UniversityYining835000China State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular ScienceFudan UniversityShanghai200433China School of Chemical Engineering and light Industry Guangdong University of TechnologyGuangzhou510006China

Combining Brownian dynamics simulations and self-consistent field theory,we demonstrate that the architectural parameters of coreshell comb-like chains have a decisive influence on their final self-assembled *** the ratio of hydrophilic and hydrophobic segments is N_(g,g)∶N_(g,r)=3∶1,no core-shell structure is observed,and unsegregated chains or clusters are *** N_(g,g)∶N_(g,r)=3∶2or 3∶3,the core-shell comb-like chains can be assembled into single micelles or structures where several small micelles are strung together by the backbone,which is similar to the pearl-necklace structure formed by the polyelectrolytes in poor *** the increase of backbone length or grafting density,the probability of forming single micelles becomes lower,but the structures of two,three or more small micelles strung together are more *** results indicate how to obtain the desired self-assembled structures of core-shell comb-like chains by regulating the architectural parameters,which could provide insights for the optimization of molecular design in various applications.

关键词： Comb-like polymer Self-assembled conformations Brownian dynamics simulations

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Copper ions-me diate d dynamic re dox-responsive microgels synergize with silicone for efficient and sustainable antibacterial properties

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Journal of Materials Science & Technology 2023年第12期143卷 253-267页

作者： huali li liuqin Zhang Xiaohu Zhang Shuwen Luo Baoshan Yang Min Wu wei-hua li Fa-Qian liu School of Chemical Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China School of Materials Science and Engineering Sun Yat-sen UniversityGuangzhou 510275China Offshore Oil Production Plant of Sinopec Shengli Oilfield Company Dongying 257237China

The antifouling of marine facilities placed below the waterline is a key constraint to the development of the marine ***,commercial Cu_(2)O-based antifouling coatings still have defects such as agglomeration,oxidation,short duration and high *** this reason,we developed for the first time a triple antifouling system consisting of Cu_(2)O@poly(NIPAM-co-DAm)(Cu_(2)O@PND)dynamic redox micro-gels triggered by copper ions and polydimethylsiloxane(PDMS).The catechol groups of PND nanogels can chelate Cu^(2+)and reduce it in situ to obtain Cu_(2)O@PND microgels,which guarantees the stable release of Cu^(+).Furthermore,Cu_(2)O remains stable and free from oxidation because of the electron transfer between PND and Cu^(2+).Finally,superior antifouling performance was achieved by combining the stable Cu^(+)re-leased from Cu_(2)O,in situ conversion of PND to hydrogel,and its oxidation to produce active substances and H_(2)O_(2),and PDMS coating with low surface energy.

关键词： Hydrogel Copper ions Dynamic redox Silicone Efficient-sustainable release Antibacterial

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A Multi-UCAV cooperative occupation method based on weapon engagement zones for beyond-visual-range air combat

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Defence Technology（防务技术） 2022年第6期18卷 1006-1022页

作者： wei-hua li Jing-ping Shi Yun-yan Wu Yue-ping Wang Yong-xi Lyu School of Automation Northwestern Polytechnical UniversityXi'an710129China Shaanxi Province Key Laboratory of Flight Control and Simulation Technology Xi'an710129China Science and Technology on Aircraft Control Laboratory FACRIXi'an710065China

Recent advances in on-board radar and missile capabilities,combined with individual payload limitations,have led to increased interest in the use of unmanned combat aerial vehicles(UCAVs)for cooperative occupation during beyond-visual-range(BVR)air ***,prior research on occupational decision-making in BVR air combat has mostly been limited to one-on-one *** such,this study presents a practical cooperative occupation decision-making methodology for use with multiple *** weapon engagement zone(WEZ)and combat geometry were first used to develop an advantage function for situational assessment of one-on-one *** encircling advantage function was then designed to represent the cooperation of UCAVs,thereby establishing a cooperative occupation *** corresponding objective function was derived from the one-on-one engagement advantage function and the encircling advantage *** resulting model exhibited similarities to a mixed-integer nonlinear programming(MINLP)*** such,an improved discrete particle swarm optimization(DPSO)algorithm was used to identify a *** occupation process was then converted into a formation switching task as part of the cooperative occupation model.A series of simulations were conducted to verify occupational solutions in varying situations,including two-on-two *** results showed these solutions varied with initial conditions and weighting *** occupation process,based on formation switching,effectively demonstrates the viability of the proposed *** cooperative occupation results could provide a theoretical framework for subsequent research in cooperative BVR air combat.

关键词： Unmanned combat aerial vehicle Cooperative occupation Beyond-visual-range air combat Weapon engagement zone Discrete particle swarm optimization Formation switching

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Optical scattering imaging with sub-nanometer precision based on position-ultra-sensitive giant Lamb shift

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Science China(Physics,Mechanics & Astronomy) 2024年第6期67卷 96-105页

作者： Zeyang liao Yu-wei Lu wei li Xue-hua Wang State Key Laboratory of Optoelectronic Materials and Technologies School of PhysicsSun Yat-sen UniversityGuangzhou 510275China Quantum Science Center of Guangdong-Hong Kong-Macao Greater Bay Area(Guangdong) Shenzhen 518045China

The Lamb shift of a quantum emitter in close proximity to a plasmonic nanostructure can be three or more orders of magnitude larger than that in the free space and is ultra-sensitive to the emitter position and *** demonstrate that this large Lamb shift can be sensitively observed from the scattering or absorption spectrum dip shift of the coupled system when the plasmonic nanoparticle or tip scans the *** these observations,we propose a scanning optical scattering imaging method based on the plasmonic-enhanced Lamb shift with achieves sub-nanometer *** method is based on the scattering or absorption spectrum of the plasmon-emitter coupling system,which is free of the fluorescence quenching problem and easier to implement in a plasmon-emitter coupling *** addition,our scheme works even if the quantum emitter is slightly below the dielectric surface,which can bring about broader applications,such as detecting atoms and molecules or quantum dots above or under a surface.

关键词： Lamb shift plasmon optical scattering imaging

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Predictive model using four ferroptosis-related genes accurately predicts gastric cancer prognosis

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 2018-2037页

作者： li Wang wei-hua Gong Department of Emergency The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina Department of Surgery The Second Affiliated Hospital Zhejiang University School of MedicineHangzhou 310052Zhejiang ProvinceChina

BACKGROUND Gastric cancer(GC)is a common malignancy of the digestive *** to global 2018 cancer data,GC has the fifth-highest incidence and the thirdhighest fatality rate among malignant *** than 60%of GC are linked to infection with Helicobacter pylori(***),a gram-negative,active,microaerophilic,and helical *** parasite induces GC by producing toxic factors,such as cytotoxin-related gene A,vacuolar cytotoxin A,and outer membrane ***,or iron-dependent programmed cell death,has been linked to GC,although there has been little research on the link between *** infection-related GC and *** To identify coregulated differentially expressed genes among ferroptosis-related genes(FRGs)in GC patients and develop a ferroptosis-related prognostic model with discrimination *** Gene expression profiles of GC patients and those with ***-associated GC were obtained from The Cancer Genome Atlas and Gene Expression Omnibus(GEO)*** FRGs were acquired from the FerrDb database.A ferroptosis-related gene prognostic index(FRGPI)was created using least absolute shrinkage and selection operator–Cox *** predictive ability of the FRGPI was validated in the GEO ***,we verified the expression of the hub genes and the activity of the ferroptosis inducer FIN56 in GC cell lines and *** Four hub genes were identified(NOX4,MTCH1,GABARAPL2,and SLC2A3)and shown to accurately predict GC and ***-associated *** FRGPI based on the hub genes could independently predict GC patient survival;GC patients in the high-risk group had considerably worse overall survival than did those in the low-risk *** FRGPI was a significant predictor of GC prognosis and was strongly correlated with disease ***,the gene expression levels of common immune checkpoint proteins dramatically increased in the highrisk subgroup of the FRGPI *** hub genes were also conf

关键词： Ferroptosis Gastric cancer Helicobacter pylori infection Immune checkpoint protein Prognostic model Ferroptosis-related gene prognostic index

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Microneedle patch loaded with ferritin-nanocaged doxorubicin for locally targeted drug delivery and efficient skin cancer treatment

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Particuology 2024年第5期88卷 282-289页

作者： Feng li Yuan Yang hua Yue Shuang Wang Xiao Zhang wei wei State Key Laboratory of Biochemical Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing100190China Key Laboratory of Biopharmaceutical Preparation and Delivery Chinese Academy of SciencesBeijing100190China School of Chemical Engineering University of Chinese Academy of SciencesBeijing100049China

Ferritin has emerged as a promising nanocarrier for delivering therapeutic agents to ***,the limited drug loading and the off-target impacts after systemic administration remain challenges for cancer treatment with ferritin-based ***,we develop a microneedle patch loaded with ferritin-nanocaged doxorubicin(DoxFe@Fn/MN)for skin cancer ***,doxorubicin(Dox)is encapsulated in ferritin(Fn)using an iron core-assisted strategy,which results in a 3.4-fold increase in Dox loading compared to the direct loading ***,a polyvinyl alcohol-based microneedle(MN)patch is used for the transdermal delivery of DoxFe@Fn,enabling targeted tumour accumulation of DoxFe@Fn and preventing off-target *** released DoxFe@Fn can bind to CD71 highly expressed on skin cancer cells,facilitating its *** a result,the DoxFe@Fn/MN therapy presents a robust antitumour effect in a melanoma tumour model,showing its potential as a promising therapeutic modality for skin cancer treatment.

关键词： Ferritin Microneedle Skin cancer Drug delivery

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Oleophobic interaction mediated slippery organogels with ameliorated mechanical performance and satisfactory fouling-resistance

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Journal of Materials Science & Technology 2022年第26期121卷 227-235页

作者： liangpeng Zeng Hongyuan Cui Huilan Peng Xiaohang Sun Yi liu Jingliang huang Xinxing lin Hui Guo wei-hua li School of Chemical Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China School of Materials Science and Engineering Sun Yat-sen UniversityGuangzhou 510275China

Owing to their inherent semi-solid property and lubricant ability,organogels manifest various unique characteristics and serve as promising candidates for ***,the poor mechanical properties of organogels often limit their practical ***,we report a simple and effective method to prepare organogels with reinforced mechanical performance and surface lubricant ability with the synergistic roles played by oleophobic and oleophilic *** rigid oleophobic chains have a poor affinity to lubricating solvent,which gives rise to high oleophobic interactions between polymer networks;the soft oleophilic chains possess a high affinity to the low surface energy solvent,which lead to high solvent content to maintain the satisfactory lubricant *** organogel of oleophobic methyl methacrylate(MMA)and oleophilic lauryl methacrylate(LMA)is chosen as a representative example to illustrate this *** the optimal composition,the as-prepared organogels offer satisfactory tensile fracture stress,fracture strain,Young’s modulus,toughness,and tearing fracture energy of 480 k Pa,550%,202 k Pa,1.14 MJ m,and 5.14 k J m,respectively,which are far beyond the classical PLMA ***,the biofouling resistance tests demonstrate 4 to 9-fold reduction of protein and bacteria adhesion on the reinforced organogels surface in comparison to the glass substrate and solvent-free dry *** simple and effective approach to toughen organogels,we hope,can be applied in various fields with different practical functional requirements in the future.

关键词： Organogels Mechanical reinforcement Fouling-resistance Slippery surface

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On traceable iterated line graph and hamiltonian path index

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Applied Mathematics(A Journal of Chinese Universities) 2024年第2期39卷 239-252页

作者： NIU Zhao-hong XIONG li-ming YANG wei-hua School of Mathematical Sciences Shanxi UniversityTaiyuan 030006China School of Mathematics and Statistics Beijing Key Laboratory on MCAACIBeijing Institute of TechnologyBeijing 100081China Department of Mathematics Taiyuan University of TechnologyTaiyuan 030024China

Xiong and liu[21]gave a characterization of the graphs G for which the n-iterated line graph L^(n)(G)is hamiltonian,for n≥*** this paper,we study the existence of a hamiltonian path in L^(n)(G),and give a characterization of G for which L^(n)(G)has a hamiltonian *** applications,we use this characterization to give several upper bounds on the hamiltonian path index of a graph.

关键词： iterated line graph traceable hamiltonian index hamiltonian path index

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