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Knockout of cryptochrome 1 disturbs the locomotor circadian rhythm and development of Plutella xylostella

Insect Science 2023年第4期30卷 1035-1045页

作者： Shao-Ping Chen Dan-feng Wang wei-feng ma Xiao-Lu Lin Guang Yang State Key Laboratory of Ecological Pest ControlforFujan and Taiwan Crops Institute of Applied EcologyFujian Agriculture and Forestry UniversityFuzhouChina Joint International Research Laboratory of Ecological Pest Control Ministry of EducationFuzhouChina Ministerial and Provincial Joint Innovation Center for Safety Production of Cross-Strait Crops Fujian Agriculture and Forestry UniversityFuzhouChina Key Laboratory of Integrated Pest management for Fujian-Taiwan Crops Ministry of AgricultureFuzhouChina Key Laboratory of Green Pest Control(Fujian Agriculture and Forestry University) Fujian Province UniversityFuzhouChina

Cryptochrome 1(CRY1)functions as a light-responsive photoreceptor,which is crucial for circadian *** identity and function of CRY1 in Plutella xylostella remain *** this study,cryl was cloned and identified in P ***,a cry1-knockout strain(Cry1-KO)of P xylostella with a 2-bp deletion was established from the strain Geneva 88(G88)using the CRISPR/Cas9 *** daily temporal os-cillation of cryl was observed in G88 and Cry1-KO,and cryl mean daily transcription of Cry1-KO was lower than that of *** G88 and Cry1-KO demonstrated rhythmic locomotion under the light/dark condition with Cryl-KO being more active than G88 in the daytime,whereas Cry1-KO completely lost rhythmicity under constant *** developmental period of pre-adult of Cry1-KO was longer than that of G88;the lifespan of the Cry1-KO male adult was shorter than that of G88;the fecundity of Cry1-KO was lower than that of G88;and Cry1-KO showed lower intrinsic rate of increase(r),net repro-duction rate(Ro),finite increase rate(a),and longer mean generation time(T)than *** results indicate that cryl is involved in the regulation of locomotor circadian rhythm and development in P xylostella,providing a potential target gene for controlling the pest and a basis for further investigation on circadian rhythms in lepidopterans.

关键词： circadian rhythm cryptochrome 1 lifespan locomotor activity Plutella xylostella reproduction

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Immune checkpoint inhibition mediated with liposomal nanomedicine for cancer therapy

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Military Medical Research 2024年第1期11卷 98-114页

作者： Guang-Long ma wei-feng Lin Faculty of Medicine Centre for Cancer ImmunologyUniversity of SouthamptonSouthampton SO166YDUK Department of Molecular Chemistry and materials Science Weizmann Institute of Science76100 RehovotIsrael Key Laboratory of Bio-Inspired Smart Interfacial Science and Technology of Ministry of Education School of ChemistryBeihang UniversityBeijing 100191China

Immune checkpoint blockade(ICB)therapy for cancer has achieved great success both in clinical results and on the *** the same time,success drives more attention from scientists to improve ***,only a small portion of patients are responsive to this therapy,and it comes with a unique spectrum of side effects termed immunerelated adverse events(irAEs).The use of nanotechnology could improve ICBs’delivery to the tumor,assist them in penetrating deeper into tumor tissues and alleviate their *** nanomedicine has been investigated and used for decades,and is well-recognized as the most successful nano-drug delivery *** successful combination of ICB with liposomal nanomedicine could help improve the efficacy of ICB *** this review,we highlighted recent studies using liposomal nanomedicine(including new emerging exosomes and their inspired nanovesicles)in associating ICB therapy.

关键词： Liposome Exosome Immune checkpoint blockade(ICB)

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The anti-Temperature-vibration properties of viscoelastic anticorrosive tape

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Petroleum Science 2022年第5期19卷 2413-2419页

作者： Hai-Liang Nie wei-feng ma Xiao-wei Hu wei Dang Jun-Jie Ren Ke Wang Jun Cao Tian Yao Xiao-Bin Liang Institute of Safety Assessment and Integrity State Key Laboratory for Performance and Structure Safety of Petroleum Tubular Goods and Equipment MaterialsCNPC Tubular Goods Research InstituteXi'an710077China No.2 Oil Extraction Plant Changqing Oilfield BranchPetroChinaGansu745100China

Viscoelastic anticorrosive tape is extensively used for repairing anticorrosive layers on compressor outlet pipelines in the oil and gas ***,there is no relevant research on the coupling effect of temperature and vibration on the performance of viscoelastic anticorrosive *** this paper,acceleration tests of temperature and vibration coupling conditions were conducted to investigate the performance of viscoelastic anticorrosive *** temperature and vibration treatment,the specimens showed wide variance in thickness,and the adhesion and chemical soaking resistance of the tape was ***,the viscoelastic anticorrosive tape still showed high *** to theoretical calculations,the tested viscoelastic body can repair pipes with a maximum diameter of 903 ***,this viscoelastic anticorrosive tape is suitable for the compressor outlets of buried pipelines with diameters smaller than 903 *** research in this paper provides a method and basis for the selection of repairing materials for the anticorrosion coatings of compressor outlet pipelines.

关键词： Station Compressor outlet Anticorrosive coating Viscoelastic anticorrosive tape

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Optimal search path planning of UUV in battlefeld ambush scene

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Defence Technology（防务技术） 2024年第2期32卷 541-552页

作者： wei feng Yan ma Heng Li Haixiao Liu Xiangyao Meng Mo Zhou Naval Research Institute Beijing100161China

Aiming at the practical application of Unmanned Underwater Vehicle(UUV)in underwater combat,this paper proposes a battlefield ambush scene with UUV considering ocean ***,by establishing these mathematical models of ocean current environment,target movement,and sonar detection,the probability calculation methods of single UUV searching target and multiple UUV cooperatively searching target are given ***,based on the Hybrid Quantum-behaved Particle Swarm Optimization(HQPSO)algorithm,the path with the highest target search probability is ***,through simulation calculations,the influence of different UUV parameters and target parameters on the target search probability is analyzed,and the minimum number of UUVs that need to be deployed to complete the ambush task is demonstrated,and the optimal search path scheme is *** method proposed in this paper provides a theoretical basis for the practical application of UUV in the future combat.

关键词： Battlefield ambush Optimal search path planning UUV path Planning Probability of cooperative search

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A Dual-Cluster-Head Based Medium Access Control for Large-Scale UAV Ad-Hoc Networks

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China Communications 2024年第5期21卷 123-136页

作者： Zhao Xinru wei Zhiqing Zou Yingying ma Hao Cui Yanpeng feng Zhiyong Key Laboratory of Universal Wireless Communications Ministry of EducationSchool of Information and Communication EngineeringBeijing University of Posts and TelecommunicationsBeijing100876China

Unmanned Aerial Vehicle(UAV)ad hoc network has achieved significant growth for its flexibility,extensibility,and high deployability in recent *** application of clustering scheme for UAV ad hoc network is imperative to enhance the performance of throughput and energy *** conventional clustering scheme,a single cluster head(CH)is always assigned in each ***,this method has some weaknesses such as overload and premature death of CH when the number of UAVs *** order to solve this problem,we propose a dual-cluster-head based medium access control(DCHmaC)scheme for large-scale UAV *** DCHmaC,two CHs are elected to manage resource allocation and data forwarding ***,two CHs work on different *** of CH is used for intra-cluster communication and the other one is for inter-cluster communication.A markov chain model is developed to analyse the throughput of the *** result shows that compared with FM-maC(flying ad hoc networks multi-channel maC,FM-maC),DCHmaC improves the throughput by approximately 20%~50%and prolongs the network lifetime by approximately 40%.

关键词： dual cluster head medium access control UAV swarm

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Stable carbon isotope composition and intrinsic water use efficiency in plants along an altitudinal gradient on the eastern slope of Yulong Snow Mountain, China

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Ecological Processes 2024年第2期13卷 218-230页

作者： feng Jiang Tao Pu Zi-Jing Xue Yan-wei ma Xiao-Yi Shi Fu-Xi Shi College of Geography and Environmental Sciences Zhejiang Normal University Yulong Snow Mountain Glacier and Environment Observation and Research Station/State Key Laboratory of Cryospheric Sciences Northwest Institute of Eco-Environment and ResourcesChinese Academy of Sciences Key Laboratory of National Forestry and Grassland Administration on Forest Ecosystem Protection and Restoration of Poyang Lake Watershed College of Forestry Jiangxi Agricultural University

Background Stable carbon isotope composition(δ13Cp) can be used to estimate the changes in intrinsic water use efficiency（iWUE） in plants,which helps us to better understand plants' response strategies to climate *** study focused on the variations in δ13Cpand iWUE for the different life-form plants（i.e.,herbs,shrubs,and trees）along an altitudinal gradient（3300,3600,3900,4100,4300,and 4500 m） on the eastern slope of Yulong Snow Mountain,southeastern margin of the Qinghai-Tibet *** response mechanisms of δ13Cpand iWUE for different life-form plants to altitude were thoroughly analyzed in this mountain *** The δ13Cpvalues of plants on the eastern slopes of Yulong Snow Mountain ranged from-30.4‰to-26.55‰,with a mean of-28.02‰,indicating a dominance of *** δ13Cpand iWUE values varied among different life-form plants in the order of herbs> shrubs> trees,particularly in 3600,3900,and 4300 ***δ13Cpand iWUE values for herbs and shrubs increased with altitude and were mainly controlled by air *** two parameters for trees exhibited a trend of initial decrease followed by an increase with *** 3900 m,the δ13Cpand iWUE values decreased with altitude,influenced by soil ***,above 3900 m,the two parameters increased with altitude,mainly regulated by air *** addition,iWUE was positively correlated with leaf P content but negatively correlated with leaf N:P ratio,especially for herbs and trees,suggesting that P plays a key role in modulating iWUE in this *** The diffe rentiated responses of water availability for different life-form plants to a higher altitudinal gradient are regulated by air temperature,soil moisture,and leaf P content in the Yulong Snow *** results provide valuable insights into understanding the wate r-carbon relationships in high-altitude ecosystems.

关键词： Stable carbon isotope Water use efficiency Altitude Life form Yulong Snow Mountain

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Gradient sparsification for efficient wireless federated learning with differential privacy

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Science China(Information Sciences) 2024年第4期67卷 272-288页

作者： Kang wei Jun LI Chuan ma Ming DING feng SHU Haitao ZHAO Wen CHEN Hongbo ZHU School of Electronic and Optical Engineering Nanjing University of Science and Technology Zhejiang Lab Key Laboratory of Computer Network and Information Integration(Southeast University) Ministry of Education Data61 Commonwealth Scientific and Industrial Research Organisation School of Information and Communication Engineering Hainan University School of Communications and Information Engineering Nanjing University of Posts and Telecommunications School of Electronic Information and Electrical Engineering Shanghai Jiao Tong University

Federated learning(FL) enables distributed clients to collaboratively train a machine learning model without sharing raw data with each other. However, it suffers from the leakage of private information from uploading models. In addition, as the model size grows, the training latency increases due to the limited transmission bandwidth and model performance degradation while using differential privacy(DP)protection. In this paper, we propose a gradient sparsification empowered FL framework with DP over wireless channels, to improve training efficiency without sacrificing convergence performance. Specifically, we first design a random sparsification algorithm to retain a fraction of the gradient elements in each client’s local model, thereby mitigating the performance degradation induced by DP and reducing the number of transmission parameters over wireless channels. Then, we analyze the convergence bound of the proposed algorithm, by modeling a non-convex FL problem. Next, we formulate a time-sequential stochastic optimization problem for minimizing the developed convergence bound, under the constraints of transmit power, the average transmitting delay, as well as the client’s DP requirement. Utilizing the Lyapunov drift-plus-penalty framework, we develop an analytical solution to the optimization problem. Extensive experiments have been implemented on three real-life datasets to demonstrate the effectiveness of our proposed algorithm. We show that our proposed algorithms can fully exploit the interworking between communication and computation to outperform the baselines, i.e., random scheduling, round robin, and delay-minimization algorithms.

关键词： federated learning differential privacy gradient sparsification Lyapunov drift convergence analysis

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MOF‐derived 1D/3D N‐doped porous carbon for spatially confined electrochemical CO2 reduction to adjustable syngas

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Carbon Energy 2024年第8期6卷 1-13页

作者： wei Zhang Hui Li Daming feng Chenglin Wu Chenghua Sun Baohua Jia Xue Liu Tianyi ma Key Laboratory for Green Synthesis and Preparative Chemistry of Advanced materials Institute of Clean Energy ChemistryCollege of ChemistryLiaoning UniversityShenyangLiaoningChina School of Science RMIT UniversityMelbourneVictoriaAustralia School of Pharmaceutical and Chemical Engineering Taizhou UniversityTaizhouZhejiangChina Department of Chemistry and Biotechnology Swinburne University of TechnologyHawthornVictoriaAustralia

Electrochemical reduction of CO_(2)to syngas(CO and H_(2))offers an efficient way to mitigate carbon emissions and store intermittent renewable energy in ***,the hierarchical one‐dimensional/three‐dimensional nitrogen‐doped porous carbon(1D/3D NPC)is prepared by carbonizing the composite of Zn‐MOF‐74 crystals in situ grown on a commercial melamine sponge(MS),for electrochemical CO_(2)reduction reaction(CO_(2)RR).The 1D/3D NPC exhibits a high CO/H_(2)ratio(5.06)and CO yield(31 mmol g^(−1)h^(−1))at−0.55 V,which are 13.7 times and 21.4 times those of 1D porous carbon(derived from Zn‐MOF‐74)and N‐doped carbon(carbonized by MS),*** is attributed to the unique spatial environment of 1D/3D NPC,which increases the adsorption capacity of CO_(2)and promotes electron transfer from the 3D N‐doped carbon framework to 1D carbon,improving the reaction kinetics of CO_(2)*** results and charge density difference plots indicate that the active site of CO_(2)RR is the positively charged carbon atom adjacent to graphitic N on 1D carbon and the active site of HER is the pyridinic N on 1D *** presence of pyridinic N and pyrrolic N reduces the number of electron transfer,decreasing the reaction kinetics and the activity of CO_(2)*** CO/H_(2)ratio is related to the distribution of N species and the specific surface area,which are determined by the degree of spatial confinement *** CO/H_(2)ratios can be regulated by adjusting the carbonization temperature to adjust the degree of spatial confinement *** the low cost of feedstock and easy strategy,1D/3D NPC catalysts have great potential for industrial application.

关键词： electrochemical CO_(2)reduction reaction melamine sponge metal‐organic frameworks porous carbon syngas

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Effect of heat treatment on microstructural evolution,mechanical properties and tribological properties of H13 steel prepared using selective laser melting

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Journal of Iron and Steel Research International 2024年第5期31卷 1246-1259页

作者： Li-xiong Han Yan Wang Shi-feng Liu Zhao-hui Zhang wei Liu Xin Yang Dang-shen ma Jian Zhou Ying-kang wei College of Metallurgical Engineering Xi’an University of Architecture and TechnologyXi’an710055ShaanxiChina Zhejiang University City College Hangzhou310015ZhejiangChina China Iron and Steel Research Institute Group Co. Ltd.Beijing100081China

H13 tool steel was successfully prepared by selective laser melting(SLM)*** effects of heat treatment on the microstructure,mechanical properties,and tribological properties of SLMed H13 steel were *** heat treatment process involved a solution treatment and a double aging treatment of the deposited H13 tool steel prepared by *** aim is to optimize the microstructure and mechanical properties of SLMed H13 *** to the rapid heating and cooling effects of SLM,carbide precipitation in the deposited H13 steel was not uniform and residual stresses were *** purpose of the solution treatment is to dissolve the solution at a high temperature to eliminate the residual stresses and defects introduced by the SLM-forming *** solution treatment and first aging treatment produced the precipitation of small carbides at the grain boundaries and inside the crystals,which increased the hardness of SLMed H13 *** hardness increased from 538±4.0 HV of the as-deposited sample to 548±5.8 HV of samples after the first aging ***,the ultimate tensile strength and the elongation at break decreased from 1882 MPa and 11.5%in the as-deposited sample to 1697 MPa and 7.9%in those after the first aging treatment,***,the friction coefficient and wear rate in the as-deposited sample decreased from 0.5160 and 2.36×10^(–6)mm^(−3)N^(−1)m^(−1)to 0.4244 and 1.04×10^(–6)mm^(−3)N^(−1)m^(−1),***,the distribution of carbides inside the crystals was not *** second aging treatment adjusted the morphology of carbide precipitation and made it more uniform,but the precipitation of carbides grew and settled at the bottom of the grain *** hardness decreased to 533±6.7 HV compared with that with the first aging treatment,but the ultimate tensile strength and plasticity reached a balance(1807 MPa,14.05%).Accordingly,the friction coefficient and wear rate also showed a stable and decreasin

关键词： Selective laser melting H13 steel Solution aging Double aging Friction and wear Retained austenite

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Silica-modified Pt/TiO_(2) catalysts with tunable suppression of strong metal-support interaction for cinnamaldehyde hydrogenation

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Chinese Journal of Chemical Engineering 2024年第6期70卷 189-198页

作者： Zhengjian Hou Yuanyuan Zhu Hua Chi Li Zhao Huijie wei Yanyan Xi Lishuang ma Xiang feng Xufeng Lin College of Chemistry and Chemical Engineering China University of Petroleum(East China)Qingdao 266580China Advanced Chemical Engineering and Energy materials Research Center China University of Petroleum(East China)Qingdao 266580China State Key Laboratory of Heavy Oil Processing China University of Petroleum(East China)Qingdao 266580China

Tuning Strong Metal-support Interactions(SMSI)is a key strategy to obtain highly active catalysts,but conventional methods usually enable TiO_(x) encapsulation of noble metal components to minimize the exposure of noble *** study demonstrates a catalyst preparation method to modulate a weak encapsulation of Pt metal nanoparticles(NPs)with the supported TiO_(2),achieving the moderate suppression of SMSI *** introduction of silica inhibits this encapsulation,as reflected in the characterization results such as XPS and HRTEM,while the Ti^(4+) to Ti^(3+) conversion due to SMSI can still be found on the support ***,the hydrogenation of cinnamaldehyde(CAL)as a probe reaction revealed that once this encapsulation behavior was suppressed,the adsorption capacity of the catalyst for small molecules like H_(2) and CO was enhanced,which thereby improved the catalytic activity and facilitated the hydrogenation of ***,the introduction of SiO_(2) also changed the surface structure of the catalyst,which inhibited the occurrence of the acetal reaction and improved the conversion efficiency of C=O and C=C *** manipulation of SMSI formation and its consequence on the performance in catalytic hydrogenation reactions are discussed.

关键词： Pt catalyst Silica modification Hydrogenation Cinnamaldehyde Strong metal-support interaction

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