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Journal of Natural Gas Chemistry 2007年第1期16卷 6-11页

作者： Yonggang wei hua Wang Fang he Xianquan Ao Chiyuan Zhang Faculty of Materials and Metallurgy Engineering Kunming University of Science and Technology Kunming 650093 Yunnan China

A new technique -- the direct partial oxidation of methane to synthesis gas using lattice oxygen in molten salts medium has been introduced. Using CeO2 as the oxygen carrier, thermodynamic data were calculated in the reaction process, and the results indicated that direct partial oxidation of methane to synthesis gas using lattice oxygen of cerium oxide is feasible in theory. In a stainless steel reactor, the effects of temperature and varying amounts of γ-Al2O3 supported CeO2 on cn4 conversion, H2 and CO selectivity, were investigated, respectively. The results show that 10% CeO2/γ-Al2O3 has the maximal reaction activity at a temperature of 865 ℃ and above, the H2/CO ratio in the gas that has been produced reaches 2 and the CH4 conversion, H2 and CO selectivity reached the following percentages： i.e. 61%, 89%, and 91% at 870 ℃, respectively. In addition, increase of reaction temperature is favorable for the partial oxidation of methane.

关键词： partial oxidation methane cerium oxide synthesis gas molten salt

Ricci-flat Graphs with Girth Four

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Acta Mathematica Sinica,English Series 2021年第11期37卷 1679-1691页

作者： wei hua he Jun LUO Chao YANG wei YUAN Hui Chun ZHANG School of Mathematics and Statistics Guangdong University of TechnologyGuangzhou 510520P.R.China School of Mathematics Sun Yat-sen UniversityGuangzhou 510275P.R.China School of Mathematics and Statistics Guangdong University of Foreign StudiesGuangzhou 510006P.R.China

Lin-Lu-Yau introduced a notion of Ricci curvature for graphs and obtained a complete classification for all Ricci-flat graphs with girth at least *** this paper,we characterize all Ricci-flat graphs of girth four with... 详细信息

关键词： Ricci curvature Ricci-flat graph vertex-disjoint

Linear Arboricity of Regular Digraphs

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Acta Mathematica Sinica,English Series 2017年第4期33卷 501-508页

作者： wei hua he Hao LI Yan Dong BAI Qiang SUN Department of Applied Mathematics Guangdong University of TechnologyGuangzhou 510006P.R.China Laboratoire de Recherche en Informatique UMR 8623C.N.R.S.-Universitg de Paris-sud91405-Orsay cedexFrance

A linear directed forest is a directed graph in which every component is a directed *** linear arboricity la(D) of a digraph D is the minimum number of linear directed forests in D whose union covers all arcs of D. For every d-regular digraph D, Nakayama and P′eroche conjecture that la(D) = d + 1. In this paper, we consider the linear arboricity for complete symmetric digraphs,regular digraphs with high directed girth and random regular digraphs and we improve some wellknown results. Moreover, we propose a more precise conjecture about the linear arboricity for regular digraphs.

关键词： Linear arboricity digraph Lovász Local Lemma random regular digraphs

Recent Advances of DNA Hydrogels in Biomedical Applications

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Journal of Analysis and Testing 2021年第2期5卷 155-164页

作者： huai-Qing Chen Wan Yang hua Zuo hua-wei he Ye-Jing Wang State Key Laboratory of Silkworm Genome Biology Biological Science Research CenterSouthwest UniversityChongqing 400715China College of Pharmaceutical Sciences Southwest UniversityChongqing 400715China Chongqing Key Laboratory of Sericultural Science Chongqing Engineering and Technology Research Center for Novel Silk MaterialsSouthwest UniversityChongqing 400715China Chongqing Key Laboratory of Soft-Matter Material Chemistry and Function Manufacturing Chongqing 400715China

DNA hydrogel is one of DNA-based nanomaterials with unique advantages such as precise self-assembly,programmability,addressability,high stability,excellent biocompatibility and biodegradability,and tunable *** features have greatly promoted the development of DNA hydrogels in various applications,especially molecular diagnostics,biosensing,drug delivery,and cancer *** this review,we briefly review the history of DNA hydrogels,the latest advances of DNA hydrogels in biomedical applications especially in biosensing,drug delivery and cancer therapy,and prospect the key challenges and future directions.

关键词： DNA hydrogels Self-assembly Biosensing Drug carrier Cancer therapy

Effect of resveratrol treatment on apoptosis and apoptotic pathways during boar semen freezing

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2020年第6期21卷 485-494页

作者： wei-hua he Xiao-hu ZHAI Xiu-jun DUAN he-shuang DI Jiangsu Agri-animal Husbandry Vocational College Taizhou 225300China

Resveratrol(3,5,4’-trihydroxystilbene,RSV) has been widely used in mammalian cells,but whether it can be used during freezing boar semen is still *** effects of RSV treatment during boar semen freezing on its anti-freezing ability,apoptosis,and possible apoptotic pathways were observed in this *** motility,mitochondrial membrane potential(ΔΨm),adenosine triphosphate(ATP) content,terminal deoxynucleotidyl transferase(TdT)-mediated dUTP nick-end labeling(TUNEL)-positive apoptotic state,and messenger RNA(mRNA) expression levels of apoptotic genes involved in different apoptotic pathways after freezing with or without RSV treatment were *** results showed that:(1) Compared with fresh sperm,the motility,normal acrosome rate,and plasma membrane integrity rate of frozen boar sperm decreased significantly(Phe sperm motility(0.44 vs.0.40,P>0.05),but it did significantly improve the normal acrosome rate(57.65% vs.47.00%,Phe rate of high mitochondrial ΔΨm of boar sperm.(3) RSV treatment significantly decreased reactive oxygen species(ROS) levels(58.65% vs.88.41%,Phe ATP content(0.49 μmol/L vs.0.25 μmol/L,Phe apoptotic rate of the freezing group(80.41%) with TUNEL detection increased significantly compared to the fresh group(9.70%,Phe apoptotic rate(68.32%,Phe genes from the death receptor-mediated apoptotic pathway(tumor necrosis factor-α(TNF-α),Fas ligand(FasL),and Caspase-8),but also the genes from the mitochondria-mediated apoptotic pathway(manganese superoxide dismutase(MnSOD),B-cell lymphoma 2(Bcl-2),Bcl-2-associated X protein(Bax),and Caspase-9) were both signific

关键词： Resveratrol(RSV) Boar semen freezing Antioxidant Mitochondrial function Apoptotic pathway

SYMBOLIC ANALYTICAL SYSTEM DEVELOPED ON MICROCOMPUTER AND SOME EXAMPLES

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Chinese Journal of Aeronautics 1992年第4期 234-242页

作者： Cao Da-wei,he hua-can,Chen Qiu(Northwestern Polytechnical University,Xi’an China)

By referring to REDUCE system,a new system or a language of non-numerical manipulationfor symbolic analysis has been built on PC *** symbolic analyticalsystem is a mathematical expert system,which makes use of the principles andmethods of artificial intelligence to the algebra,calculus and other calculating *** to being a system for calculating manipulation,it is also a language for thestatement of *** a set of simple syntax,users write program in its own *** system can operate both in interactive manner or in program *** are given in two-dimensional analysis form or FORTRAN source program formwhich may be used in numerical calculation *** system has complete systematic controlfunctions and error-handling capability,allowing job—*** job may be interruptedif *** and function-keys provide great convenience to *** two non-numerical examples of the system are presented.

关键词： RK SYMBOLIC ANALYTICAL SYSTEM DEVELOPED ON MICROCOMPUTER AND SOME EXAMPLES LISP

Decreases of voltage-dependent K~+ currents densities in ventricular myocytes of guinea pigs by chronic oxidant stress

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Acta Pharmacologica Sinica 2004年第6期25卷 49-53页

作者： De-li DONG, Yan LIU, Yu-hong ZHOU,wei-hua SONG, he WANG, Bao-feng YANG2 Department ofpharmacology, Harbin Medical University, Harbin 150086, China Department of pharmacology Harbin Medical University

AIM: To determine the changes of delayed rectifier K+ currents (Ik) and inward rectifier K+ currents (Ik1) in the ventricular myocytes of guinea pigs during the gradual apoptotic process by the chronic oxidant stress treatment. METHODS: H2O250 μmol/L (24 h) was used for inducing apoptosis in the cardiomyocytes culture of neonatal rats and to treat the isolated ventricular myocytes of adult guinea pigs in vitro for 24 h. Apoptosis was evaluated by TUNEL methods and voltage-dependent K+ currents were recorded by patch-clamp techniques. RESULTS: H2O2 50 μmol/L (24 h)induced cell apoptosis in the cardiomyocytes culture of neonatal rats. This concentration was used to treat the isolated ventricular myocytes of adult guinea pigs in vitro for 24 h and the voltage-dependent K+ currents densities (Ik, Ik1) were down-regulated. The densities of the delayed rectifier K+ currents (Ik) in 50 μmol/L H2O2 group were 2.52±0.57 pA/pF vs 5.73±1.84 pA/pF in the control group at +50 mV (n=8, Phe densities of the inward rectifier K+ currents (Ik1) in 50 μmol/L H2O2 group were -13.9± 2.70 pA/pF, 2.52±0.57 pA/pF vs -59.7±11.9 pA/pF, 5.73±1.84 pA/pF in the control group at -120 mV (n=8, Phe extent of inward rectifier property of Ik1 was weakened by 50 μmol/L H2O2treatment. CONCLUSION: The densities of Ik, Ik1 in the cardiomyocytes of guinea pigs were down- regulated and the inward rectifier property of Ik1 was weakened during the gradual apoptotic process after 50 μmol/L H2O2 treatment for 24 h.

关键词： hydrogen peroxide potassium apoptosis cardiac myocytes

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2017年国际经济热点问题研究动态

经济纵横 2018年第3期 123-128页

作者：卫兴华何召鹏中国人民大学北京100872 中央财经大学经济学院北京100081

2017年,我国学界对国际经济热点问题进行了广泛研讨。本文主要对"逆全球化"现象与全球经济治理变革、"一带一路"倡议与推进策略及出口贸易、全球价值链与我国贸易地位、资本账户开放、人民币国际化与汇率、对外直接投资与跨国并购等相... 详细信息

2017年,我国学界对国际经济热点问题进行了广泛研讨。本文主要对"逆全球化"现象与全球经济治理变革、"一带一路"倡议与推进策略及出口贸易、全球价值链与我国贸易地位、资本账户开放、人民币国际化与汇率、对外直接投资与跨国并购等相关主题的研究成果进行综述。

关键词： “逆全球化” 全球经济治理 “一带一路” 对外贸易国际金融对外投资

Infiltration by monocytes of the central nervous system and its role in multiple sclerosis: reflections on therapeutic strategies

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Neural Regeneration Research 2025年第3期20卷 779-793页

作者： Guangyong Zhang Qing Yao Chubing Long Pengcheng Yi Jiali Song Luojia Wu wei Wan Xiuqin Rao Yue Lin Gen wei Jun Ying Fuzhou hua Department of Anesthesiology the Second Affiliated Hospital of Nanchang UniversityNanchangJiangxi ProvinceChina Key Laboratory of Anesthesiology of Jiangxi Province NanchangJiangxi ProvinceChina

Mononuclear macrophage infiltration in the central nervous system is a prominent feature of neuroinflammation. Recent studies on the pathogenesis and progression of multiple sclerosis have highlighted the multiple roles of mononuclear macrophages in the neuroinflammatory process. Monocytes play a significant role in neuroinflammation, and managing neuroinflammation by manipulating peripheral monocytes stands out as an effective strategy for the treatment of multiple sclerosis, leading to improved patient outcomes. This review outlines the steps involved in the entry of myeloid monocytes into the central nervous system that are targets for effective intervention: the activation of bone marrow hematopoiesis, migration of monocytes in the blood, and penetration of the blood–brain barrier by monocytes. Finally, we summarize the different monocyte subpopulations and their effects on the central nervous system based on phenotypic differences. As activated microglia resemble monocyte-derived macrophages, it is important to accurately identify the role of monocyte-derived macrophages in disease. Depending on the roles played by monocyte-derived macrophages at different stages of the disease, several of these processes can be interrupted to limit neuroinflammation and improve patient prognosis. here, we discuss possible strategies to target monocytes in neurological diseases, focusing on three key aspects of monocyte infiltration into the central nervous system, to provide new ideas for the treatment of neurodegenerative diseases.

关键词： blood–brain barrier macrophages monocytes multiple sclerosis neuroinflammation review therapy

基于度电成本的绝缘栅双极型晶体管模块的冗余设计

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科学技术与工程 2017年第3期17卷 240-246页

作者：聂伟王华君何昌国河北工业大学控制科学与工程学院天津300130 天津明阳风电设备有限公司天津300384

在海上风电变流器中,IGBT模块等功率器件是容易失效的部件之一。海上风电场的恶劣环境对风电变流器的可靠性提出了更高的要求。为了提高风电变流器整体的可靠性,提出了风电变流器IGBT模块的3种冗余设计方案和相应的控制策略;并对3种冗... 详细信息

在海上风电变流器中,IGBT模块等功率器件是容易失效的部件之一。海上风电场的恶劣环境对风电变流器的可靠性提出了更高的要求。为了提高风电变流器整体的可靠性,提出了风电变流器IGBT模块的3种冗余设计方案和相应的控制策略;并对3种冗余设计方案的可靠性进行比较,得出了3种冗余设计方案均可提高风电变流器的运行可靠性的结论;最后使用度电成本的概念,分别计算了应用3种冗余设计方案的海上风电场20 a全寿命周期内的度电成本,得出了第一种冗余设计方案;即冗余一支桥臂,可以使整个海上风电场的度电成本最低的结论。这为以后风电变流器IGBT模块的冗余设计提供了参考。

关键词：风电变流器绝缘栅双极型晶体管(IGBT)模块冗余设计度电成本