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南京医科大学学报（自然科学版） 2007年第10期27卷 1071-1071页

作者： Chen, R. q.u, W. Liu, Z. L. Cao, X. J. Zhu, T. Li, A. P. wei, q. y. Zhou, J. W. Univ Texas MD Anderson Canc Ctr Dept Epidemiol Houston TX 77030 USA.

Interactions of IL-12A and IL-12B Poly.orphisms on the Risk of Cervical Cancer in Chinese Women

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南京医科大学学报（自然科学版） 2009年第3期29卷 360-360页

作者： Chen, X. J. Han, S. P. Wang, S. N. Zhou, X. y. Zhang, M. F. Dong, J. Shi, X. y. q.an, N. F. Wang, X. R. wei, q. y. Shen, H. B. Hu, Z.B. Nanjing Med Univ Ctr Canc Dept Epidemiol & Biostat Nanjing Peoples R China Naniing Med Univ Lab Reprod MedNanjingPeoples R China Nanjing Med Univ Affiliated Hosp 1 Dept GynecolNanjing Peoples R China Nanjing Med Univ Nanjing Matern & Child Hlth Hosp Nanjing Peoples R China Tumor Hosp Nantong City. NantongPeoples R China Univ Texas MD Anderson Canc Ctr Dept Epidemiol Houston TX 77030 USA

Genome engineering technologies for targeted genetic modification in plants

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Journal of Forestry.Research 2018年第4期29卷 875-887页

作者： wei Tang Anna y. Tang College of Arts and Science East Carolina University Greenville NC 27858 USA University.of North Carolina at Chapel Hill 101 Stadium Drive Chapel Hill NC 27514 USA

Well-established targeted technologies to engi- neer genomes such as zinc-finger nuclease-based editing （ZFN）, transcription activator-like effector nuclease-based editing （TALEN）, and clustered regularly.interspaced short palindromic repeats and associated protein sy.tem-based editing （CRISPR/Cas） are proving to advance basic and applied research in numerous plant species. Compared with sy.tems using ZFNs and TALENs, the most recently.developed CRISPR/Cas sy.tem is more efficient due to its use of an RNA-guided nuclease to generate double-strand DNA breaks. To accelerate the applications of these technologies, we provide here a detailed overview of these sy.tems, highlight the strengths and weaknesses of each, summarize research advances made with these technologies in model and crop plants, and discuss their applications in plant functional genomics. Such targeted approaches for genetically.modify.ng plants will benefit agricultural production in the future.

关键词： Double-stranded DNA break Genomeediting CRISPR sy.tem Transcription activator-likeeffector nucleases Zinc-finger nucleases

Extraction of affine invariant features for shape recognition based on ant colony.optimization

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Journal of Sy.tems Engineering and Electronics 2011年第6期22卷 1003-1009页

作者： y.xing Mao Ching y. Suen wei He State Key.Laboratory.of Power Transmission Eq.ipment ＆ Sy.tem Security.and New Technology Chongqing University Chongqing 400044 E R. China Centre for Pattern Recognition and Machine Intelligence Concordia University Montreal QC H3G 1M8 Canada

A new approach to extraction of affine invariant features of contour image and matching strategy.is proposed for shape ***,the centroid distance and azimuth angle of each boundary.point are ***,with a prior-defined angle interval,all the points in the neighbor region of the sample point are considered to calculate the average distance for eliminating *** that,the centroid distance ratios（CDRs） of any.two opposite contour points to the bary.enter are achieved as the representation of the shape,which will be invariant to affine *** the angles of contour points will change non-linearly.among affine related images,the CDRs should be resampled and combined seq.entially.to build one-by.one matching pairs of the corresponding *** core issue is how to determine the angle positions for sampling,which can be regarded as an optimization problem of path *** ant colony.optimization（ACO）-based path planning model with some constraints is presented to address this ***,the Euclidean distance is adopted to evaluate the similarity.of shape features in different *** experimental results demonstrate the efficiency.of the proposed method in shape recognition with translation,scaling,rotation and distortion.

关键词： shape recognition affine transformation centroid distance ratio(CDR) ant colony.optimization(ACO) path planning.

Potentially.functional poly.orphisms of EXO1 and risk of lung cancer in a Chinese population: A case-control analy.is

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南京医科大学学报(自然科学版) 2008年第10期 1368-1368页

作者： Jin, G. F. Wang, H. F. Hu, Z. B. Liu, H. L. Sun, W. W. Ma, H. X. Chen, D. Miao, R. F. Tian, T. Jin, L. wei, q. y. Huang, W. Lu, D. R. Shen, H. B. Nanjing Med Univ, Canc Res Ctr, Dept Epidemiol & Biostat, Nanjing 210029, Peoples R China. Chinese Natl Human Genome Ctr, Shanghai MOST Key.Lab Hlth & Dis Genom, Dept Genet, Shanghai 201203, Peoples R China. Fudan Univ, Sch Life Sci, State Key.Lab Genet Engn, Shanghai 200433, Peoples R China. Univ Texas MD Anderson Canc Ctr, Dept Epidemiol, Houston, TX 77030 USA.

Exonuctease 1(EXO1) is an important nucleases involved in mismatch repair sy.tem that contributes to maintain genomic stability. to modulate DNA recombination, and to mediate cell cy.le arrest. Potentially.functional poly.orphisms in EXO1 may.alter cancer risks by.influencing the repair activity.of EX01. Therefore, we hy.othesized that single nucteotide poly.orphisms(SNPs) in EX01 were associated with risk of lung cancer. To test this hy.othesis, we genoty.ed five common SNPs (rs1776177A/G, rs1047840G/A(Gtu589Ly.), rs1776148G/A(Gly.70Glu), rs9350C/T(Leu757Pro) and rs851797T/C) that tag eight SNPs located at exon regions of EX01 by.using the Ilumina high-throughput genoty.ing platform in 500 incident lung cancer cases and 517 cancerfree controls in a Chinese population. Significant differences of allele and genoty.e distributions were observed in Gtu589Ly. (rs1047840) of EX01 between the cases and controls (P = 0.028 and 0.025 for allele and genoty.e distributions, respectively.. Lo- gistic regression analy.es revealed that individuals carry.ng the variant 589Ly. allele(589Glu/Ly. or 589Ly./Ly.) had a significantly.increased risk of lung cancer[adjusted odds ratio(OR) = 1.41, 95% confidential interval(Cl) = 1.09-1.84] compared with those who carried the wild-ty.e homozy.ote (589Glu/Glu). Furthermore, we found that haploty.e AAGTT was more freq.ent in cases than in controls(P y. poly.orphism and its surrounding regions might be genetic susceptibility.markers for lung cancer in this study.population. (c)2007 Elsevier Ireland Ltd. All rights reserved.

关键词： EXO1 MMR Poly.orphisms lung cancer susceptibility molecular epidemiology.nonpoly.osis colorectal-cancer dna mismatch repair single nucleotide poly.orphisms human exonuclease-i mutation avoidance gene recombination inactivation variants tobacco

FATIGUE PROPERTIES OF AUSTEMPERED DUCTILE IRON(ADI)IN WATER ENVIRONMENT

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Acta Metallurgica Sinica(English Letters) 2004年第2期17卷 122-130页

作者： q.Z.Cai B.K.wei y.Tanaka StateKey.abofPlasticFormingSimulation＆Dies／MouldTechnology FacultyofMaterialsScienceandEngineeringHuazhongUniversityofScienceandTechnologyWuhan430074China DepartmentofMechanicalSy.temsEngineering MuroranInstituteofTechnologyMuroran050-8585Japan

The acicular ferrite in austempered ductile iron (ADI) matrix around graphite wascorroded preferentially.in wet condition, promoting crack origination and propagationand resulting in the disappearance of ADI fatigue limit. ADI fatigue strength wasgradually.reduced with increasing the time of test and was reduced by.50% in wetcondition at 10~7 cy.les compared with the fatigue limit in dry.condition. The fatiguestrength variation of ferritic ductile iron in wet condition was similar to that of ADI.The ferritic ductile iron, however, has better corrosion resistance so that the fatiguestrength was lowered only.by.10% in wet condition at 10~7 cy.les compared with thefatigue limit in dry.condition. On the other hand, the fatigue limits of ADI and ferriticductile iron were dropped by.32% and 25% in tap water dipping 480h/dry.conditionrespectively.compared with those in dry.condition. The reduction of fatigue limit wasattributed to corrosion pits formation correlated with stress concentration, resultingin origination and propagation of fatigue crack.

关键词： anstempered ductile iron water environment corrosion fatigue crack fatigue strength

Nitrogen Contents on Tribological Properties of Magnetron Sputtered SICN Coatings

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材料热处理学报 2004年第05B期25卷 854-857页

作者： TIETUNSUN y.q.FU J.wei H.J.DU Departmentofphy.ics ShanghaiJiaotongUniversityShanghaiChina／／SchoolofMechanicalandProductionEngineeringNanyangTechnologicalUniversitySingapore639798 SchoolofMechanicalandProductionEngineering NanyangTechnologicalUniversitySingapore639798／／SingaporeInstituteofManufacturingTechnologySingapore71NanyangDriveSingapore638075 SingaporeInstituteofManufacturingTechnology -Singapore71NanyangDrivesingapore638075

Silicon carbonitride (SiCN) coatings were deposited on silicon and tungsten carbide substrates by.co-sputtering silicon and carbon in argon and nitrogen mixture atmosphere using magnetron-sputtering sy.tem. The effect of the N2 concentration, RF substrate bias voltage and target current on film deposition rate, roughness, adhesion, mechanical and tribological properties of coatings were investigated. The deposition rate was found to increase with the increasing nitrogen concentration. X-ray.photoelectron spectroscopy.analy.is showed that high nitrogen concentration in the nitrogen-argon gas mixture enhanced the incorporation of C and N but reduced the incorporation of Si. SiCN coatings have good tribological properties at a N2 concentration of approximately.60%.

关键词： SiCN涂层磁控管溅射含氮量硬度磨损

Basic features of the multiscale interaction between tearing modes and slab ion-temperature-gradient modes

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Chinese Phy.ics B 2019年第12期28卷 237-247页

作者： L wei Z X Wang J q.Li Z q.Hu y.Kishimoto Key.Laboratory.of Materials Modification by.Laser Ionand Electron Beams(Ministry of Education)School of PhysicsDalian University of TechnologyDalian 116024China Southwestern Institute of Phy.ics Chengdu 610041China Graduate School of Energy.Science Kyoto UniversityGokashoUjiKyoto 1-0011Japan

Nonlinear interaction between tearing modes(TM) and slab ion-temperature-gradient(ITG) modes is numerically.investigated by.using a Landau fluid model. It is observed that the energy.spectra with respect to wavenumbers become broader during the transition phase from the ITG-dominated stage to TM-dominated stage. Accompanied with the fast growth of the magnetic island, the freq.ency.of TM/ITG with long/short wavelength fluctuations in the electron/ion diamagnetic direction decreases/increases respectively. The decrease of TM freq.ency.is identified to result from the effect of the profile flattening in the vicinity.of the magnetic island, while the increase of the freq.encies of ITG fluctuations is due to the eigenmode transition of ITG induced by.the large scale zonal flow and zonal current related to TM. Roles of zonal current induced by.the ITG fluctuations in the instability.of TM are also analy.ed. Finally. the electromagnetic transport features in the vicinity.of the magnetic island are discussed.

关键词： magnetic reconnection tearing modes magnetohy.rody.amics drift waves nonlinear phenomena

Extraction of copper ions by.supercritical carbon dioxide

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Journal of Environmental Sciences 2000年第4期12卷 444-447页

作者： Cui, Z. Liu, J. Gao, L. wei, y. Dept. of Environmental Engineering Shandong University Jinan 250100 China

Complexation combined with supercritical fluid extraction was used to extract Cu2+ in this study. The effects of pressure, temperature, volume of CO2 on the efficiency.of extraction were sy.tematically.investigated. At the optimum condition a 57.32% recovery.was achieved. Addition of suitable amount of methanol (v/v = 5%) to the supercritical CO2 can increase in the extraction of Cu2+ (72.69%, RSD = 2.12%, n = 3). And the recovery.can further increase in the presence of non-ionic surfactant Triton X-100 because of its function of solubilization. Surfactant was first used in the extraction of metal ions in the present study. and the results are satisfied (90.52%, RSD = 2.20%, n = 3).

关键词： Carbon dioxide Chelation Copper Methanol Positive ions Pressure effects Solubility Surface active agents Thermal effects

Pollen and Plant Reproduction Biology. Blooming from East to West

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Molecular Plant 2013年第4期6卷 995-997页

作者： Alice y. Cheung Ravi Palanivelu wei-Hua Tang Hong-wei Xue wei-Cai y.ng Department of Biochemistry.and Molecular Biology University of Massachusetts Amherst MA USA University.of Arizona School of Plant Sciences Tucson AZ USA Shanghai Institute of Plant Phy.iology.and Ecology Chinese Academy of Sciences Shanghai China Institute of Genetics and Developmental Biology Chinese Academy of Sciences Beijing China

The idea of assembling a Special Issue on Pollen Tube and Reproduction in Molecular Plant was conceived during the organization of the 2012 Pollen Biology.International Sy.posium and Workshop held at the Shanghai Institute of Plant Phy.iology.and Ecology.（SIPPE）, Chinese Academy.of Science （CAS）, 27-31 October 2012. wei-Hua Tang of the SIPPE led the organization, with the support of Hong-wei Xue, Director of SIPPE acting as Chair of the Organization Committee. The 2-d sy.posium was attended by.about 100 international participants and focused on reports and discus- sions on the most recent research activities in the field. The 2-d workshop that followed provided a forum for in-depth introduction on various aspects of pollen and plant reproduc- tion biology.to about 200 graduate students, postdoctoral fellows, and new investigators to the field.

关键词： MEETINGS POLLEN tube PLANT reproduction COMPUTATIONAL biology PLANT cells & tissues CONGRESSES