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中国护理管理 2019年第7期19卷 1119-1120页

作者： Roger watson 陈雪《Journal of Advanced Nursing》杂志英国赫尔大学健康和社会护理学院《中国护理管理》杂志社

随着我国护理学科快速发展,护理人员科研水平逐年提升,与国际护理同行间交流学术成果的需求日益迫切。培养高水平的护理科研与英文护理论文撰写人才,是提升我国护理学科国际彩响力的重要途径。为竝,我社于2019年4月10-13日举办了“英文... 详细信息

随着我国护理学科快速发展,护理人员科研水平逐年提升,与国际护理同行间交流学术成果的需求日益迫切。培养高水平的护理科研与英文护理论文撰写人才,是提升我国护理学科国际彩响力的重要途径。为竝,我社于2019年4月10-13日举办了“英文护理论文撰写与投稿培训班”。通过4天的深度培训,采用小班讨论式的教学方法,详细介绍国外最新护理研究方法、英文护理论文写作要求、SCI期刊审稿流程等,并提供面对面的个性化指导。Roger watson教授作为国际知名期刊《Journal of Advanced Nursing》的主编,具有丰富的科研经验,担任本次培训班的主要授课教师,他结合在中国及世界各地授课的经验,反思及总结了一些经常被问道却无法作出回答的问题,并与本刊编辑一起,针对这些事情给出建议,旨在鼓励减少作者对编辑的依赖,提升自身科研及写作能力,促进期刊学术研究质量的提升。

关键词：编辑护理学科 Nursing 科研水平论文撰写授课教师培训班护理人员

Cytoplasmic expression of p27^(kip1) is associated with a favourable prognosis in colorectal cancer patients

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World Journal of Gastroenterology 2006年第39期12卷 6299-6304页

作者： Nicholas FS watson Lindy G Durrant John H Scholefield Zahra Madjd Duncan Scrimgeour Ian Spendlove Ian O Ellis Poulam M Patel Section of Gastrointestinal Surgery University of Nottingham Queens' Medical Centre Nottingham United Kingdom Academic Department of Clinical Oncology University of Nottingham Institute of Infections Immunity and Inflammation City Hospital Nottingham United Kingdom Academic Department of Clinical Oncology (with LGD ZM DS and PMP) University of Nottingham Institute of Infections Immunity and Inflammation City Hospital Nottingham United Kingdom Department of Histopathology Nottingham City Hospital and University of Nottingham Nottingham United Kingdom

AIM: To evaluate the prognostic significance of p27kip1 in colorectal cancer patients. METHODS: Cytoplasmic and nuclear p27kip1 expression was evaluated in 418 colorectal cancers using tissue microarrays. Data were associated with known patient and tumor variables and long-term patient outcomes, providing further insight into the mechanisms by which p27kip1 may influence tumor development. RESULTS: Nuclear and cytoplasmic p27Kip1 expressions were detected in 59% and 19% of tumors respectively. Cytoplasmic p27Kip1 was almost invariably associated with positive nuclear p27Kip1 expression. Neither case correlat- ed with known clinical or pathological variables, includ- ing tumor stage, grade or extramural vascular invasion. Furthermore, nuclear p27kip1 expression had no impact on survival. However, we identified a significant correla- tion between expression of cytoplasmic p27kip1 and longer disease-specific survival times. On multivariate analysis, TNM stage and extramural vascular invasion were highly significant independent prognostic factors, with positive cytoplasmic p27 expression showing a trend towards im- proved patient survival (P = 0.059).CONCLUSION: These findings support the recent evi- dence that cytoplasmic p27kip1 has a distinct and impor- tant biological role that can influence tumor outcome.

关键词： Colorectal cancer Tissue microarray p27^Kip1 Prognostic factor

Pterygium associated with light-emitting diode use:a case report

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Annals of Eye Science 2022年第4期7卷 65-68页

作者： Fiona S.Lau Stephanie L.watson Kenneth Gek-Jin Ooi Ophthalmology Department Prince of Wales HospitalRandwickNSWAustralia Faculty of Medicine School of Medical SciencesUniversity of New South WalesRandwickNSWAustralia Cornea Unit Sydney Eye HospitalSydneyNSWAustralia Save Sight Institute Discipline of OphthalmologySydney Medical SchoolThe University of SydneySydneyNSWAustralia Sydney Eye Clinic DarlinghurstNSWAustralia

Background:Pterygium is a sun-related ocular surface disease secondary to ultraviolet(UV)radiation *** occupational UV exposure is known to occur secondary to sun *** present a unique case of pterygium associated with indoor occupational light-emitting diode(LED)exposure not previously described in the *** Description:A mobile phone repairer presented with blurred vision and a superotemporal pterygium of his dominant left eye associated with a magnifying glass LED work lamp was *** was excised routinely with conjunctival autografting to the *** confirmed benign pterygium and recovery was uncomplicated with resolution of ***:The development of pterygium in our patient may have arisen due to the LED lamp’s wavelengths possibly falling within the UV as well as the upper end of the visible light radiation *** the increasing reliance on LED light sources in modern life,ocular conditions arising from exposure to these radiation sources may now need to be listed in the differential diagnoses of patients with *** UV protection counselling for these types of lights may also now need to be considered.

关键词： Pterygium light-emitting diode(LED) ultraviolet light damage ocular surface disease case report

Human caring for patients suffering from major infectious disease-nurses’ entire use of self

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护理学杂志 2022年第7期37卷 95-96页

作者： Liu Yilan He Jiao Zhang Fengjian Wang Shuang Hu Deying Jean watson Department of Nursing Union Hospital of Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Pediatric Union Hospital of Tongji Medical College Huazhong University of Science and Technology watson Caring Science Institute

Human caring is regarded as the essence and core of *** on ***′s human caring science theory,nursing staff in Wuhan Union Hospital and other healthcare institutions have delivered warm human caring service in patients′ daily *** the outbreak of major infectious disease-pandemic of COVID-19,patients are suffering from great psychological distress and *** nursing professionals around the world,nurses in Wuhan,Hubei,China,along with the colleagues from the National Aid Medical Team,used entire of themselves to conduct diversity human caring measures to patients suffering from the major infectious disease with love and responsibilities,which greatly demonstrated the essence and value of nursing care,and has wide implications for further development of nursing.

关键词： human caring major infectious disease nursing COVID-19 caring relationship

miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus

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World Journal of Gastroenterology 2011年第8期17卷 1036-1044页

作者： Cameron M Smith David I watson Mary P Leong George C Mayne Michael Z Michael Bas PL Wijnhoven Damian J Hussey Department of Surgery Flinders University Bedford Park Department of Gastroenterology and Hepatology Flinders University Bedford Park Department of Surgery Erasmus Medical Centre

AIM: To investigate miR-200 family expression in Barrett's epithelium, gastric and duodenal epithelia, and esophageal adenocarcinoma. METHODS: Real-time reverse transcriptase-polymerase chain reaction was used to measure miR-200, ZEB1 and ZEB2 expression. Ingenuity Pathway Analysis of miR-200 targets was used to predict biological outcomes. RESULTS: Barrett's epithelium expressed lower levels of miR-141 and miR-200c than did gastric and duodenal epithelia (P < 0.001). In silico analysis indicated roles for the miR-200 family in molecular pathways that distinguish Barrett's epithelium from gastric and duodenalepithelia, and which control apoptosis and proliferation. All miR-200 members were downregulated in adenocarcinoma (P < 0.02), and miR-200c expression was also downregulated in non-invasive epithelium adjacent to adenocarcinoma (P < 0.02). The expression of all miR-200 members was lower in Barrett's epithelium derived high-grade dysplastic cell lines than in a cell line derived from benign Barrett's epithelium. We observed signif icant inverse correlations between miR-200 family expression and ZEB1 and ZEB2 expression in Barrett's epithelium and esophageal adenocarcinoma (P < 0.05). CONCLUSION: miR-200 expression might contribute to the anti-apoptotic and proliferative phenotype of Barrett's epithelium and regulate key neoplastic processes in this epithelium.

关键词： miRNA Barrett’s esophagus Esophageal adenocarcinoma miR-200 Epithelial to mesenchymal transition Apoptosis Proliferation Epithelium

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发表中医相关论文的注意事项

中国护理管理 2020年第3期20卷 479-480页

作者： Roger watson 陈雪《Journal of Advanced Nursing》杂志英国赫尔大学健康和社会护理学院《中国护理管理》杂志社

中医在中国已有几千年的发展历史,作为可供普通民众选择的治疗方案,中医也早已被正式批准。在西方,中医越来越受到一些人的欢迎,他们对西医的疗效和不良反应有些顾虑。在西方,中医归属于补充和替代医疗的范畴,补充和替代医疗的拥护者很... 详细信息

中医在中国已有几千年的发展历史,作为可供普通民众选择的治疗方案,中医也早已被正式批准。在西方,中医越来越受到一些人的欢迎,他们对西医的疗效和不良反应有些顾虑。在西方,中医归属于补充和替代医疗的范畴,补充和替代医疗的拥护者很可能是中医的拥护者。作为编辑,我们看到有关中医研究论文的来稿量有所增加,我们热切希望有关中医的研究报告遵循尽可能高的标准进行发表。

关键词：中医研究不良反应来稿量替代医疗注意事项普通民众治疗方案

PM_(2.5) and PM_(10-2.5) chemical composition and source apportionment near a Hong Kong roadway

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Particuology 2015年第1期13卷 96-104页

作者： Yan Cheng Shuncheng Lee Zhaolin Gu Kinfai Ho Yunwei Zhang Yu Huang Judith C.Chow John G.watson Junji Cao Renjian Zhang Department of Environmental Science and Technology School of Human Settlements and Civil EngineeringXi'an Jiaotong University State Key Laboratory of Loess Quaternary Geology Institute of Earth and EnvironmentChinese Academy of Sciences Department of Civil and Structural Engineering Research Center for Environmental Technology and ManagementThe Hong Kong Polytechnic University School of Public Health and Primary Care The Chinese University of Hong Kong Division of Atmospheric Sciences Desert Research Institute Key Laboratory of Regional Climate-Environment Research for Temperate East Asia Institute of Atmospheric PhysicsChinese Academy of Sciences

Twenty-four-hour PM2.5 and PM10 samples were collected simultaneously at a highly trafficked road-side site in Hong Kong every sixth day from October 2004 to September 2005. The mass concentrations of PM2.5, PMlo-2.5 （defined as PM10 - PM2.5）, organic carbon （OC）, elemental carbon （EC）, water-soluble ions, and up to 25 elements were determined. Investigation of the chemical compositions and potential sources revealed distinct differences between PM2.5 and PM10-2.5. The annual average mass concentrations were 55.5 ＋ 25.5 and 25.9±15.7μg/m^3 for PM2.5 and PM10-2.5, respectively. EC, OM （OM = OC × 1.4）, and ammonium sulfate comprised over -82% of PM2.5, accounting for -29%, -27%, and -25%, respectively, of the PM2.5 mass. Low OC/EC ratios （less than 1） for PM2.5 suggested that fresh diesel-engine exhaust was a major contributor. Seven sources were resolved for PM2.5 by positive matrix factorization （PMF） model, including vehicle emissions （-29%）, secondary inorganic aerosols （-27%）, waste incinera- tor/biomass burning （-23%）, residual oil combustion （-10%）, marine aerosols （-6%）, industrial exhaust （-4%）, and resuspended road dust （-1%）. EC and OM comprised only -19% of PM10-2.5. The average OC/EC ratio of PM10-2.5 was 7.8± 14.2, suggesting that sources other than vehicular exhaust were important contributors. The sources for PM10-2.5 determined by the PMF model included -20% traffic-generated resuspension （e.g., tire dust/brake linear/petrol evaporation）, -17% locally resuspended road dust, -17% marine aerosols, -12% secondary aerosols/field burning, and -11% vehicle emissions.

关键词： PM2.5 PM10-2.5 Roadside Chemical composition Source apportionment Hong Kong

A Japanese version of the stressors in nursing students(SINS)scale

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International Journal of Nursing Sciences 2018年第2期5卷 181-185页

作者： Roger watson Kumi Watanabe Ayako Yamashita Mieko Yamaguchi Caroline Bradbury-Jones Fiona Irvine University of Hull HullHU67RXUK Kagawa University Kagawa Prefecture761-0793Japan Niimi College Niimi718-8585Japan Okayama Prefectural University OkayamaJapan University of Birmingham BirminghamB152TTUK

Objectives:To translate and study the factor structure of a Japanese version of the Stressors in Nursing Students ***:The Stressors in Nursing Students scale was translated into Japanese and administered to a large cohort(N=1298)of female Japanese nursing students across five universities and across all four years of the nursing *** data were analysed using exploratory factor ***:Exploratory factor analysis revealed four factors:‘Clinical’;‘Conflict and confidence’;‘Education’;and‘Free time’.The relationship between the total score on the Stressors in Nursing Students scale and the demographic aspects of the sample was weak but there was a significant increase in the perception of stressors between first and second year ***:There were similarities and differences between the perception of stressors by nursing students in Japan compared with,for example,the United Kingdom and China *** a fourfactor structure was found here,the distribution of items in the Stressors in Nursing Students scale differed from previous studies in the United Kingdom and China with the‘Free time’factor being unique to this *** is an issue for nursing students and is related to the specific stressors they encounter in the process of their work and *** can inform the development of strategies to reduce such stressors among nursing students in multiple,global contexts.

关键词： Nursing students Factor analysis Japan Stressors

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