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Trends of SARS-CoV-2 Infection in Rural Area in Sentinel Community-Based Surveillance——China,December 2022 to January 2023

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China CDC weekly 2023年第11期5卷 241-247页

作者： Wenzhan Jing Fan Ding Yanping Zhang Guoqing Shi Jue Liu Yu Wu Fangyuan Li Wenxin Yan Chenyuan Qin Min Liu Qun Li wannian liang Vanke School of Public Health Tsinghua UniversityBeijingChina Institute for Healthy China Tsinghua UniversityBeijingChina Chinese Center for Disease Control and Prevention BeijingChina School of Public Health Peking UniversityBeijingChina

Introduction:In late 2022,a rapid transmission of Omicron variants of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)occurred throughout *** purpose of this study was to provide the latest data and evaluate trends of SARS-CoV-2 infection in rural China among the community ***:Data on SARS-CoV-2 infection among approximately 90,000 participants in rural China were collected by the National Sentinel Community-Based Surveillance(NSCS)*** were tested for SARS-CoV-2 infection(defined as positive for SARS-CoV-2 nucleic acid or antigen)twice weekly from December 16,2022 to January 12,*** daily average of newly positive rate and its estimated daily percentage change were calculated to describe the national and regional trends of SARS-CoV-2 infection in rural ***:In rural China,the daily average new positive rate of SARS-CoV-2 infection peaked at 4.79%between December 20–22,2022 and then decreased to 0.57%between January 10–12,2023,with an average decrease of 29.95%per *** peak of new SARS-CoV-2 infection was slightly earlier and lower in North China(5.28%between December 20–22,2022)than in South China(5.63%between December 23–26,2022),and then converged from December 30,2022 to January 2,*** peak of 6.09%occurred between December 20–22,2022 in eastern China,while the peak of 5.99%occurred later,between December 27–29,2022,in central ***:Overall,the epidemic wave in rural China peaked between December 20–22,2022,and passed quickly following the optimization of prevention and control ***,SARSCoV-2 infection in community populations in rural China is sporadic.

关键词： China Rural prevention

Trends of SARS-CoV-2 Infection in Sentinel Community-Based Surveillance After the Optimization of Prevention and Control Measures—China,December 2022-January 2023

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China CDC weekly 2023年第7期5卷 159-164页

作者： Jue Liu Fan Ding Yu Wu Wenzhan Jing Wenxin Yan Chenyuan Qin Fangyuan Li Yanping Zhang Min Liu wannian liang Qun Li School of Public Health Peking UniversityBeijing MunicipalityChina Chinese Center for Disease Control and Prevention Beijing MunicipalityChina Vanke School of Public Health Tsinghua UniversityBeijing MunicipalityChina

Introduction:On December 7,2022,China implemented the“Ten New Measures”to optimize its prevention and control measures for coronavirus disease 2019(COVID-19).To provide the latest data after the optimization,we evaluated trends of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection among the community population in ***:We utilized data from the National Sentinel Community-Based Surveillance(NSCS)system in China to assess trends of SARS-CoV-2 *** is a national community-based surveillance cohort with 0.42 million participants from all 31 provincial-level administrative divisions(PLADs)and Xinjiang Production and Construction Corps(XPCC).Participants were tested for infection twice a week(a total of eight rounds)from December 16,2022 to January 12,***-CoV-2 infection was defined as testing positive for SARS-CoV-2 nucleic acid or *** calculated the daily average of newly positive rates of SARS-CoV-2 ***:In this national cohort,the daily average newly positive rate of SARS-CoV-2 infection decreased from 4.13% in Round 1(December 16-19,2022)to 0.69% in Round 8(January 10-12,2023).The epidemic peak occurred in Round 2(December 20-22,2022).Similar trends were observed in urban areas(decreasing from 4.65% to 0.73%),rural areas(decreasing from 2.83% to 0.57%),the eastern region(decreasing from 4.18% to 0.67%),the central region(decreasing from 5.43% to 0.61%),and the western region(decreasing from 3.01%to 0.77%).Conclusions:NSCS data showed that the peak of SARS-CoV-2 infection in China had ***-2 infection in community populations in China is currently at a low epidemic level.

关键词： Round prevention utilized

Trends of SARS-CoV-2 Infection Among Couriers in Risky Business After the Optimization of Prevention and Control Measures——China,December 2022 to January 2023

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China CDC weekly 2023年第11期5卷 248-254页

作者： Yu Wu Fan Ding Jue Liu Wenzhan Jing Wenxin Yan Chenyuan Qin Fangyuan Li Yanping Zhang Guoqing Shi wannian liang Qun Li Min Liu School of Public Health Peking UniversityBeijingChina Chinese Center for Disease Control and Prevention BeijingChina Vanke School of Public Health Tsinghua UniversityBeijingChina Institute for Healthy China Tsinghua UniversityBeijingChina

Introduction:On December 7,2022,China implemented“Ten New Measures”to optimize prevention and control measures for coronavirus disease 2019(COVID-19).The purpose of this study was to evaluate the national and regional trends of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection among couriers in China from December 2022 to January ***:Data from the National Sentinel Community-based Surveillance in China was utilized,including participants from 31 provincial-level administrative divisions and Xinjiang Production and Construction *** were tested for SARS-CoV-2 infection twice a week from December 16,2022 to January 12,*** was defined as a positive result for SARS-CoV-2 nucleic acid or *** daily average newly positive rate of SARSCoV-2 infection and the estimated daily percentage change(EDPC)were ***:In this cohort,8 rounds of data were *** daily average newly positive rate of SARS-CoV-2 infection decreased from 4.99%in Round 1 to 0.41%in Round 8,with an EDPC of−33.0%.Similar trends of the positive rate were also observed in the eastern(EDPC:−27.7%),central(EDPC:−38.0%)and western regions(EDPC:−25.5%).Couriers and community population showed a similar temporal trend,with the peak daily average newly positive rate of couriers being higher than that of community *** Round 2,the daily average newly positive rate of couriers decreased sharply,becoming lower than that of community population in the same ***:The peak of SARS-CoV-2 infection among couriers in China has *** couriers are a key population for SARS-CoV-2 infection,they should be monitored continuously.

关键词： Round sharply prevention

Immunohistochemical localization of Ca^(2+)/calmodulin-dependent kinase in tobacco

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Chinese Science Bulletin 2001年第3期46卷 230-233页

作者： YANG wannian, liang Shuping & LU YingtangCenter of Developmental Biology, College of Life Science, Wuhan University, Wuhan 430072, China Center of Developmental Biology College of Life Science Wuhan University Wuhan China

The existence of Ca2+/calmodulin-dependent kinase (CaM kinase, CaMK) in tobacco is verified immuno-logically and its distribution in different tissues of tobacco is studied. It has been demonstrated that CaMK is mainly distributed in early developing anthers, developing ovules and embryos, lateral root primordium, apical meristem and leaf primordium of buds and mesophyll cells and developing vascular bundles of leaves. There is enormous CaM kinase distributed in leaf epidermis fair cells and guard cells of stomas too. Little kinase is found in mature stem or root cells. The distribution properties of CaM kinase in tobacco are consistent with those of CaM, suggesting that there exists the Ca2+ signal transduction pathway mediated by CaM kinase in tobacco and it plays an important role in the plant growth and development.

关键词： CaM kinase immunohistochemical localization tobacco anthers.

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全球新冠疫苗研发与接种策略进展

中华疾病控制杂志 2023年第8期27卷 955-962页

作者：吴俣刘珏刘民梁万年北京大学公共卫生学院流行病与卫生统计学系重大疾病流行病学教育部重点实验室(北京大学)北京100191 清华大学万科公共卫生与健康学院北京100084

WHO于2023年5月5日宣布新型冠状病毒感染(corona virus disease 2019,COVID⁃19)疫情不再构成国际关注的突发公共卫生事件。全球疫情相对稳定,但是各国仍不能放松对COVID⁃19的警惕。接种新冠疫苗仍是有效的预防手段。本文主要围绕当前全... 详细信息

WHO于2023年5月5日宣布新型冠状病毒感染(corona virus disease 2019,COVID⁃19)疫情不再构成国际关注的突发公共卫生事件。全球疫情相对稳定,但是各国仍不能放松对COVID⁃19的警惕。接种新冠疫苗仍是有效的预防手段。本文主要围绕当前全球新冠疫苗研发进展、不同国家疫苗接种策略调整情况等进行对比分析,并结合WHO推荐对新冠疫苗接种策略的最新指导意见,分析探讨全球新冠疫苗研发及各国疫苗接种策略对我国的启示,提出适合我国国情的针对性疫苗接种建议。

关键词：新型冠状病毒感染疫苗接种策略世界卫生组织

新型冠状病毒Omicron变异株的流行病学特征及防控研究

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中国全科医学 2022年第1期25卷 14-19页

作者：吴俣刘珏刘民梁万年北京大学公共卫生学院北京市100191 清华大学万科公共卫生与健康学院北京市100084

Omicron(B.1.1.529)变异株于2021年11月24日首次从南非报告给世界卫生组织,截至2021年12月8日全球共有57个国家和地区报告了Omicron感染病例。目前Omicron变异株在部分非洲国家已成为主导毒株,且传播速度快。尽管Omicron变异株引起的疾... 详细信息

Omicron(B.1.1.529)变异株于2021年11月24日首次从南非报告给世界卫生组织,截至2021年12月8日全球共有57个国家和地区报告了Omicron感染病例。目前Omicron变异株在部分非洲国家已成为主导毒株,且传播速度快。尽管Omicron变异株引起的疾病症状较轻,多数病例为无症状感染者和轻型患者,但病例数量的快速增长可能给全球卫生系统带来沉重压力。此外,Omicron变异株的变异来源、传播特征、疫苗抗性等尚不明确,给各国和地区的疫情防控带来很大挑战。本文就Omicron变异株的病原学特征、变异来源、传播特征及可能的机制、流行现状、疫苗对其保护效果、防控措施等方面的研究进展进行综述,以期为科学防控Omicron变异株所致疫情提供参考。

关键词：新型冠状病毒 Omicron关切变异株新型冠状病毒肺炎流行病学综述

新型冠状病毒Omicron变异株亚型BA.4与BA.5的流行病学特征及防控研究

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中国全科医学 2022年第30期25卷 3721-3725页

作者：吴俣刘珏刘民梁万年北京大学公共卫生学院流行病与卫生统计学系北京市100191 清华大学万科公共卫生与健康学院北京市100084

全球新型冠状病毒肺炎疫情仍处于大流行状态,Omicron仍是全球优势株,约占全球基因序列的99%。全球多个地区正在经历第7波疫情,主要由Omicron变异株亚型BA.4和BA.5引起,目前对于Omicron变异株亚型BA.4和BA.5的流行病学特征尚不明确,给各... 详细信息

全球新型冠状病毒肺炎疫情仍处于大流行状态,Omicron仍是全球优势株,约占全球基因序列的99%。全球多个地区正在经历第7波疫情,主要由Omicron变异株亚型BA.4和BA.5引起,目前对于Omicron变异株亚型BA.4和BA.5的流行病学特征尚不明确,给各国家和/或地区的疫情防控带来很大挑战。本文就Omicron变异株亚型BA.4和BA.5的发现与流行现状、潜伏期、传播力、临床症状、病死率、疫苗对其保护效果等方面的研究进展进行综述,以期为科学防控Omicron变异株亚型BA.4和BA.5所致疫情提供参考。

关键词：新型冠状病毒 Omicron变异株 BA.4亚型 BA.5亚型流行病学疾病传播传染性疫苗体征和症状

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新时期健康中国建设中的医防协同:理论机制与政策演变

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中国科学基金 2023年第3期37卷 451-460页

作者：刘珏闫温馨刘民梁万年北京大学公共卫生学院北京100191 清华大学万科公共卫生与健康学院北京100084 清华大学健康中国研究院北京100084

我国医防协同的实践由来已久,医防协同已成为我国新时期健康中国建设中全方位、全周期保障人民健康的重要途径。尽管我国的医防协同工作已经取得进展,但其相对割裂的现状并未发生根本性扭转。以此为背景,结合自2018年以来对不同地区、... 详细信息

我国医防协同的实践由来已久,医防协同已成为我国新时期健康中国建设中全方位、全周期保障人民健康的重要途径。尽管我国的医防协同工作已经取得进展,但其相对割裂的现状并未发生根本性扭转。以此为背景,结合自2018年以来对不同地区、不同部门的现场调研以及现有研究,本文介绍了新时期我国医防协同的定义、政策演进过程及内涵,并设计了医防协同的理论机制模型,揭示了医疗服务体系与公共卫生体系整合的组织基础、服务供给内容及协同机制设计,为国内和国际整合型医疗卫生服务体系改革及治理提供理论基础、改革路径和中国经验。

关键词：医防协同政策演变理论机制体系协同服务整合

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四十年中国热浪归因死亡负担时空变化史

Science Bulletin 2022年第13期67卷 1340-1344,M0004页

作者：陈慧琪赵亮董伟程亮亮蔡闻佳杨军鲍俊哲梁信忠 Shakoor Hajat 宫鹏梁万年黄存瑞 School of Public Health Sun Yat-sen UniversityGuangzhou 510080China Shanghai Key Laboratory of Meteorology and Health Shanghai Meteorological ServiceShanghai 200030China The State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Key Laboratory of Meteorological Disaster Ministry of Education&Joint International Research Laboratory of Climate and Environment Change&Collaborative Innovation Center on Forecast and Evaluation of Meteorological DisastersNanjing University of Information Science and TechnologyNanjing 210044China Department of Earth System Science Tsinghua UniversityBeijing 100084China Institute for Environmental and Climate Research Jinan UniversityGuangzhou 510632China School of Public Health Zhengzhou UniversityZhengzhou 450001China Earth System Science Interdisciplinary Center&Department of Atmospheric and Oceanic Science University of MarylandCollege Park MD 20742USA Department of Epidemiology and Population Health London School of Hygiene and Tropical MedicineLondon WC1E 7HTUK Department of Earth Sciences the University of Hong KongHong Kong 999077China Vanke School of Public Health Tsinghua UniversityBeijing 100084China Institute of Healthy China Tsinghua UniversityBeijing 100084China

热浪通过增加死亡和发病风险导致巨大的公共卫生负担.而在气候变暖与社会经济发展相交织的风险下,中国人群所面临的热浪导致的健康负担的时间演变规律、空间分布特征及其驱动因素仍然存在大量空白.本研究应用基于事件的归因损失评估方... 详细信息

热浪通过增加死亡和发病风险导致巨大的公共卫生负担.而在气候变暖与社会经济发展相交织的风险下,中国人群所面临的热浪导致的健康负担的时间演变规律、空间分布特征及其驱动因素仍然存在大量空白.本研究应用基于事件的归因损失评估方法定量评估了过去40年格点水平的每日热浪归因死亡人数.研究发现,热浪相关死亡人数具有快速增长、非线性和极端性的特征,40年间增加了4倍,2010年代年均归因死亡人数达15500人.归因死亡负担还呈现强烈的区域异质性,华东和华中地区负担更重.随着时间的推移,中国可归因死亡人数上升的主要影响因素是增加的热浪发生频率,其次是人口增长和老龄化.这项工作为民众提供了更为直观的高温健康危害信息,同时为制定有针对性的气候变化适应措施提供重要信息.

关键词：社会经济发展气候变化适应区域异质性死亡人数损失评估公共卫生极端性发病风险