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Research on the dynamics of the South china Sea opening:Evidence from analogue modeling

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Science china Earth Sciences 2006年第10期49卷 1053-1069页

作者： SUN zhen1,2, ZHOU Di1, ZHONG Zhihong3, xia Bin2, QIU Xuelin1, ZENG Zuoxun4 & JIANG Jianqun5 1. CAS Key Laboratory of Marginal Sea Geology, South china Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, china 2. CAS Key Laboratory of Marginal Sea Geology, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, china 3. Department of Technology, Shenzhen branch of CNOOC, Guangzhou 510240, china 4. Faculty of Earth Sciences, china university of Geosciences, Wuhan 430074, china 5. Hainan Oil & Gas Exploration Company, Liaohe Oilfield Petrochina, Panjin 124010, china 1. CAS Key Laboratory of Marginal Sea Geology South China Sea Institute of Oceanology Chinese Academy of Sciences Guangzhou 510301 China 2. CAS Key Laboratory of Marginal Sea Geology Guangzhou Institute of Geochemistry Chinese Academy of Sciences Guangzhou 510640 China 3. Department of Technology Shenzhen Branch of CNOOC Guangzhou 510240 China 4. Faculty of Earth Sciences China University of Geosciences Wuhan 430074 China 5. Hainan Oil & Gas Exploration Company Liaohe Oilfield PetroChina Panjin 124010 China

Independent of Indochina extrusion, the South china Sea experienced a process from passive continental rifting to marginal sea drifting. According to the fault patterns in the Beibu Gulf basin and the Pearl River Mouth basin, the continental rifting and early spreading stage from 32 to 26 Ma were controlled by extensional stress field, which shifted clockwise from southeastward to south southeastward. From 24 Ma on, the sea spread in NW-SE direction and ceased spreading at around 15.5 Ma. Integrated geological information with the assumption that the South china Sea developed along a pre-Cenozoic weakness zone, we did analogue experiments on the South china Sea evolu- tion. Experiments revealed that the pre-existing weakness zone goes roughly along the uplift zone between the present Zhu-1 and Zhu-2 depression. The pre-existing weakness zone is composed of three segments trending NNE, roughly EW and NEE, respectively. The early opening of the South china Sea is accompanied with roughly 15° clockwise rotation, while the SE sub-sea basin opened with SE extension. Tinjar fault was the western boundary of the Nansha block (Dangerous Ground), while lupar fault was the eastern boundary of the Indochina, NW-trending rift belt known as Zengmu basin developed between above two faults due to block divergent of Indochina from Nansha. In the experiment, transtensional flower structures along NW-trending faults are seen, and slight inversion occurs along some NE-dipping faults. The existence of rigid massifs changed the orientations of some faults and rift belt, and also led to deformation concentrate around the massifs. The rifting and drifting of the South china Sea might be caused by slab pull from the proto South china Sea subducting toward Borneo and/or mantle flow caused by India-Asia collision.

关键词： South china Sea, rifting and drifting, clockwise rotation, analogue modeling, rigid massifs.

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有氧健身操对女青年身体形态和机能的影响

体育学刊 2003年第1期10卷 61-62页

作者：王晓贞李太行中国矿业大学体育系江苏徐州221008 东北大学秦皇岛分校体育部河北秦皇岛066000

对持续参加 6个月以上有氧健身操的部分女青年锻炼前后身体形态指标和机能指标进行测试 ,结果显示 :长期参加有氧健身操锻炼可消除体内多余脂肪、降低体脂 ,增强肌力 ,使外型更加健美和谐 ;同时有效地改善心肺功能 ,提高人体的有氧耐力。

关键词：有氧健身操女青年身体形态生理机能

三河北工区双复杂滩坝砂储层精细描述方法应用与效果

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石油物探 2024年第5期63卷 1040-1050页

作者：夏连军张军华朱相羽王喜安罗震中国石化江苏油田分公司物探研究院江苏南京210046 中国石油大学(华东)地球科学与技术学院山东青岛266580 中国石化江苏油田分公司江苏扬州225000

苏北盆地三河北滩坝砂储层具有“盖储叠合、厚度变化,储层信号弱、岩性相变”的盖层、储层双复杂特点,其精细描述较常规滩坝砂储层更为困难。为此,首先对目标区开展井震标定分析,明确阜二段3个砂组的主要地震特征,根据其特点,提出“提频... 详细信息

苏北盆地三河北滩坝砂储层具有“盖储叠合、厚度变化,储层信号弱、岩性相变”的盖层、储层双复杂特点,其精细描述较常规滩坝砂储层更为困难。为此,首先对目标区开展井震标定分析,明确阜二段3个砂组的主要地震特征,根据其特点,提出“提频+去屏蔽+90°相移”的研究思路与对策,采用压缩感知方法进行拓频处理,在此基础上利用多道匹配追踪方法进行去强屏蔽处理,最后利用90°相移技术精细刻画砂体。模型测试与实际资料应用结果表明:(1)针对变厚度的复杂盖层,基于压缩感知反射系数稀疏反演的提频目标处理,可以有效分离叠合的复合波;(2)利用幅度可调制的多道匹配追踪方法,能可控去除顶部强屏蔽层的部分能量,使储层内砂组反射同相轴与厚度相一致;(3)90°相移处理能直观地解释有利砂体;(4)将优势地震属性与T_(0)构造图相融合,并结合地震相分析,可以较好地判识研究区滩坝砂体的分布区域。该方法对复杂滩坝砂储层砂体刻画具有理论研究与推广应用价值。

关键词：滩坝砂压缩感知匹配追踪 90°相移属性融合储层精细描述

Ultrasound-guided paravertebral nerve block anesthesia on the stress response and hemodynamics among lung cancer patients

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World Journal of Clinical Cases 2022年第7期10卷 2174-2183页

作者： Shu-Qing zhen Ming Jin Yong-Xue Chen Jian-Hua Li Hua wang Hui-xia Chen Department of Anesthesiology Handan Central HospitalHandan 056001Hebei ProvinceChina Department of Anesthesiology Affiliated Hospital of Hebei University of EngineeringHandan 056002Hebei ProvinceChina

BACKGROUND Thoracic surgery for radical resection of lung tumor requires deep anesthesia which can lead to an adverse inflammatory response,loss of hemodynamic stability,and decreased immune ***,we evaluated the feasibility and benefits of ultrasound-guided paravertebral nerve block anesthesia,in combination with general anesthesia,for thoracic surgery for lung *** block was performed by diffusion of anesthetic drugs along the paravertebral space to achieve unilateral multi-segment intercostal nerve and dorsal branch nerve *** To evaluate the application of ultrasound-guided paravertebral nerve block anesthesia for lung cancer surgery to inform *** The analysis was based on 140 patients who underwent thoracic surgery for lung cancer at our hospital between January 2018 and May *** were randomly allocated to the peripheral+general anesthesia(observation)group(n=74)or to the general anesthesia(control)group(n=66).Patients in the observation group received ultrasound-guided paravertebral nerve block anesthesia combined with general anesthesia,with those in the control group receiving an epidural block combined with general *** outcomes included the operative and anesthesia times,as well as the mean arterial pressure(MAP),heart rate(HR),and blood oxygen saturation(SpO;)measured before surgery,15 min after anesthesia(T1),after intubation,5 min after skin incision,and before extubation(T4).RESULTS The dose of intra-operative use of remifentanil and propofol and the postoperative use of sufentanil was lower in the observation group(1.48±0.43 mg,760.50±92.28 mg,and 72.50±16.62 mg,respectively)than control group(P1 through T4),MAP and HR values were higher in the observation than control group(MAP,90.20±9.15 mmHg,85.50±7.22 mmHg,88.59±8.15 mmHg,and 90.02±10.02 mmHg,respectively;and HR,72.39±8.22 beats/min,69.03±9.03 beats/min,70.12±8.11 beats/min,and 71.24±9.01 beat

关键词： Ultrasound-guided paravertebral nerve block anesthesia Anesthesia lung cancer Stress response Hemodynamics

甘蓝型油菜株高及其相关性状的主基因+多基因遗传分析

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西北农业学报 2018年第4期27卷 528-536页

作者：刘霞张冰冰马兵赵娜田正书秦梦凡王阳郎丽娜刘亚萍黄镇徐爱遐西北农林科技大学农学院陕西杨凌712100 陕西省种子管理站杨凌试验站陕西杨凌712100

油菜株高对产量、抗逆性尤其是抗倒伏性有重要影响,适当降低株高可提高油菜抗性和收获指数进而提高产量。甘蓝型油菜(Brassica napus L.)矮秆自交系‘74-1002’具有早熟、分枝多、抗倒伏等优良性状,是进行油菜株高遗传和矮化育种的良好... 详细信息

油菜株高对产量、抗逆性尤其是抗倒伏性有重要影响,适当降低株高可提高油菜抗性和收获指数进而提高产量。甘蓝型油菜(Brassica napus L.)矮秆自交系‘74-1002’具有早熟、分枝多、抗倒伏等优良性状,是进行油菜株高遗传和矮化育种的良好材料。以高秆甘蓝型油菜自交系‘HN92’为母本,‘74-1002’为父本,杂交构建6世代遗传群体(P1、P2、F1、F2、B1和B2),对6世代群体的株高及其相关性状进行度量,采用主基因+多基因混合遗传模型进行遗传分析。结果表明:株高(PH)、主花序长度(MIL)及一次有效分枝高度(VBH)均受到2对加性主基因控制,并存在加性—显性多基因效应,PH和MIL的最适遗传模型为E-0模型(MX2-ADI-ADI),VBH的最适遗传模型为E-3模型(MX2-A-AD);有效分枝节间距(IL)和有效分枝数(BN)的遗传均只受加性—显性—上位多基因控制,无主基因效应,其最适遗传模型为C-0模型(PG-ADI)。在B1、B2和F2世代中,PH的主基因+多基因遗传率最高,分别为71.22%、78.71%、81.87%;其次是VBH和MIL,分离世代主基因+多基因平均遗传率分别为57.10%和44.09%;IL和BN的遗传率偏低,3个世代主基因+多基因平均遗传率分别为15.24%和9.68%。相关性分析表明:PH与VBH、MIL和IL的相关性表现为极显著的正相关,相关系数分别为0.533、0.721和0.520。因此,在甘蓝型油菜理想株高育种进程中,在早代对株高进行选择是有效的,该研究也为后期开展株高相关性状QTL分析奠定基础,有利于加快油菜株高分子标记辅助育种进程。

关键词：甘蓝型油菜株高主基因+多基因混合遗传模型遗传分析

Tocilizumab in patients with moderate or severe COVID-19: a randomized, controlled, open-label, multicenter trial

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Frontiers of Medicine 2021年第3期15卷 486-494页

作者： Dongsheng wang Binqing Fu zhen Peng Dongliang Yang Mingfeng Han Min Li Yun Yang Tianjun Yang Liangye Sun Wei Li Wei Shi Xin Yao Yan Ma Fei Xu xiaojing wang Jun Chen Daqing xia Yubei Sun Lin Dong Jumei wang xiaoyu Zhu Min Zhang Yonggang Zhou Aijun Pan xiaowen Hu xiaodong Mei Haiming Wei xiaoling Xu Department of Pulmonary and Critical Care Medicine the First Affiliated Hospital of University of Science and Technology of China(Anhui Provincial Hospital)Hefei 230001China Division of Life Sciences and Medicine University of Science and Technology of ChinaHefei 230027China Intensive Care Unit the First Affiliated Hospital of University of Science and Technology of China(Anhui Provincial Hospital)Hefei 230001China Drug Clinical Trail Institution the First Affiliated Hospital of University of Science and Technology of China(Anhui Provincial Hospital)Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001China Department of Infectious Diseases Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430000China Department of Respiratory Medicine the Second People’s Hospital of FuyangFuyang 236000China Department of Respiratory Medicine National Key Clinical SpecialtyBranch of National Clinical Research Center for Respiratory DiseaseXiangya HospitalCentral South UniversityXiangya Lung Cancer CenterXiangya HospitalCentral South UniversityHunan Provincial Clinical Research Center for Respiratory DiseasesChangsha 410000China lu’an People’s Hospital Affiliated to Anhui Medical university Lu’an 237005China Department of Pulmonary and Critical Care Medicine the First Affiliated Hospital of Bengbu Medical CollegeClinical Research Center for Respiratory Disease(tumor)in Anhui ProvinceBengbu 233004China Department of Respiratory Medicine Anqing Hospital Affiliated to Anhui Medical UniversityAnqing 246000China The First Affiliated Hospital of Nanjing Medical university Nanjing 210000China Department of Rheumatology and Immunology the First Affiliated Hospital of University of Science and Technology of China(Anhui Provincial Hospital)Hefei 230001China Department of Oncology the First Affiliated Hospital of University of Science and Technology of China(Anhui Provincial Hospital)Hefei 230001China Department of Endocrinology

Tocilizumab has been reported to attenuate the“cytokine storm”in COVID-19 *** attempted to verify the effectiveness and safety of tocilizumab therapy in COVID-19 and identify patients most likely to benefit from this *** conducted a randomized,controlled,open-label multicenter trial among COVID-19 *** patients were randomly assigned in a 1:1 ratio to receive either tocilizumab in addition to standard care or standard care *** cure rate,changes of oxygen saturation and interference,and inflammation biomarkers were ***-three patients were randomized to the tocilizumab group,and 32 patients to the control *** cure rate in the tocilizumab group was higher than that in the control group,but the difference was not statistically significant(94.12%vs.87.10%,rate difference 95%CI−7.19%–21.23%,P=0.4133).The improvement in hypoxia for the tocilizumab group was higher from day 4 onward and statistically significant from day 12(P=0.0359).In moderate disease patients with bilateral pulmonary lesions,the hypoxia ameliorated earlier after tocilizumab treatment,and less patients(1/12,8.33%)needed an increase of inhaled oxygen concentration compared with the controls(4/6,66.67%;rate difference 95%CI−99.17%to−17.50%,P=0.0217).No severe adverse events *** mild temporary adverse events were recorded in tocilizumab recipients(20/34,58.82%)than the controls(4/31,12.90%).Tocilizumab can improve hypoxia without unacceptable side effect profile and significant influences on the time virus load becomes *** patients with bilateral pulmonary lesions and elevated IL-6 levels,tocilizumab could be recommended to improve outcome.

关键词： tocilizumab coronavirus disease 2019(COVID-19) cytokine storm

Characterization of chromosome segment substitution lines reveals candidate genes associated with the nodule number in soybean

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Journal of Integrative Agriculture 2022年第8期21卷 2197-2210页

作者： ZOU Jia-nan ZHANG Zhan-guo KANG Qing-lin YU Si-yang wang Jie-qi CHEN Lin LIU Yan-ru MA Chao ZHU Rong-sheng ZHU Yong-xu DONG xiao-hui JIANG Hong-wei WU xiao-xia wang Nan-nan HU zhen-bang QI Zhao-ming LIU Chun-yan CHEN Qing-shan XIN Da-wei wang Jin-hui College of Agriculture Northeast Agricultural UniversityHarbin 150030P.R.China Suihua branch of Heilongjiang Academy of Agricultural Sciences Suihua 152000P.R.China Soybean Research Institute Jilin Academy of Agricultural SciencesChangchun 130033P.R.China Jiamusi branch of Heilongjiang Academy of Agricultural Sciences Jiamusi 154000P.R.China

Soybean is one of the most important food crops *** other legumes,soybean can form symbiotic relationships with Rhizobium *** fixation of soybean via its symbiosis with Rhizobium is pivotal for sustainable *** Ⅲ effectors(T3Es)are essential regulators of the establishment of the symbiosis,and nodule number is a feature of nitrogen-affected ***,genes encoding T3Es at quantitative trait loci(QTLs)related to nodulation have rarely been *** segment substitution lines(CSSLs)have a common genetic background but only a few loci with heterogeneous genetic information;thus,they are suitable materials for identifying candidate genes at a target *** this study,a CSSL population was used to identify the QTLs related to nodule number in *** nucleotide polymorphism(SNP)markers and candidate genes within the QTLs interval were detected,and it was determined which genes showed differential expression between *** candidate genes(GmCDPK28,GmNAC1,GmbHLH,and GmERF5)linked to the SNPs were identified as being related to nodule traits and pivotal processes and pathways involved in symbiosis establishment.A candidate gene(GmERF5)encoding a transcription factor that may interact directly with the T3E NopAA was *** confirmed CSSLs with important segments and candidate genes identified in this study are valuable resources for further studies on the genetic network and T3Es involved in the signaling pathway that is essential for symbiosis establishment.

关键词： soybean TypeⅢeffectors nodule number chromosome segment substitution lines

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豚鼠源马链球菌兽疫亚种的分离鉴定

中国兽医杂志 2024年第4期60卷 86-91页

作者：李艳红白和平信玉春郭柯宇王金锋夏力亮吴同垒史秋梅乐亭县农业农村局河北唐山063699 河北科技师范学院河北省预防兽医学重点实验室河北秦皇岛066604 河北省廊坊市永清县农业农村局河北廊坊065600 河北硕博畜牧服务有限公司河北唐山063500

为了查明河北省唐山市某豚鼠养殖场发病豚鼠感染的病原菌,本试验采集发病豚鼠的眼角脓性分泌物,采用细菌分离纯化、革兰染色、生化鉴定、16S rRNA基因PCR扩增方法对分离菌进行鉴定,通过K-B试纸法检测分离菌株对24种抗菌药的敏感性,试管... 详细信息

为了查明河北省唐山市某豚鼠养殖场发病豚鼠感染的病原菌,本试验采集发病豚鼠的眼角脓性分泌物,采用细菌分离纯化、革兰染色、生化鉴定、16S rRNA基因PCR扩增方法对分离菌进行鉴定,通过K-B试纸法检测分离菌株对24种抗菌药的敏感性,试管二倍稀释法测定19种中药对该分离菌株的最小抑菌浓度(MIC)和最小杀菌浓度(MBC),并通过动物回归试验检测该分离菌株的致病性。结果显示,分离菌株在血琼脂培养基培养24 h生长为针尖状透明菌落、呈β溶血,革兰染色为阳性圆球状、3~5个连接呈短链状,生化特性与马链球菌兽疫亚种相符,将其命名为MLQJ-1;16S rRNA序列比对结果显示,MLQJ-1与马链球菌兽疫亚种同源性高达99.72%,在系统进化树中处于同一分支,鉴定为马链球菌兽疫亚种;MLQJ-1对24种抗菌药的敏感性不同,对青霉素、头孢曲松和阿莫西林等8种抗菌药敏感,对阿米卡星、新霉素和卡那霉素等10种抗菌药耐药;苦地丁、苦参、黄芩和千里光对MLQJ-1的MIC值介于1.9~15.6 mg/mL,MBC值介于1.9~31.2 mg/mL;小鼠腹腔接种MLQJ-1菌液后24 h内全部死亡。结果表明,马链球菌兽疫亚种为本次发病豚鼠的病原菌,青霉素、头孢曲松和苦地丁等药物对该菌具有较强的抑菌效果。

关键词：豚鼠马链球菌兽疫亚种分离鉴定药敏试验

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热扩散对高碳线材碳偏析和网状渗碳体的影响

金属热处理 2019年第1期44卷 241-245页

作者：鲁修宇刘静夏艳花王贞张帆任安超蒋跃东武汉科技大学钢铁冶金及资源利用省部共建教育部重点实验室湖北武汉430081 宝钢股份中央研究院武汉分院湖北武汉430080

改编了碳偏析指数随温度及时间的变化模型,研究了一种线材碳偏析指数在热扩散试验中的变化规律,通过试验验证了碳偏析模型的有效性,并根据模型公式预测了铸坯碳偏析指数需要的热扩散时间。试验结果表明:线材在1200℃经2 min和4 min热扩... 详细信息

改编了碳偏析指数随温度及时间的变化模型,研究了一种线材碳偏析指数在热扩散试验中的变化规律,通过试验验证了碳偏析模型的有效性,并根据模型公式预测了铸坯碳偏析指数需要的热扩散时间。试验结果表明:线材在1200℃经2 min和4 min热扩散后,其碳偏析可以降低至1. 10和1. 05以下,空冷组织网状渗碳体级别显著降低。线材热扩散试验数据与模拟数值趋势一致,存在着线材升温至稳定所需的约0. 5 min差值。经过数值模拟,铸坯经过1200℃-590 min热扩散后偏析指数可降低至要求范围,但在实际操作中需考虑铸坯在加热过程中的热扩散。

关键词：高碳线材热扩散碳偏析网状渗碳体