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Smell of the sea on a not-so-faraway planet?

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The Innovation 2023年第6期4卷 5-6页

作者： Wei wang Zewen Jiang CAS Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy of ScienoesDatun Road A20Beijing 100101China School of Astronomy and Space Science University of Chinese Academy of Sciences(UCAS)Yuquan Road A19Bejjing 100049China

On September 12,2023,exciting news appear ed in ar Xv about the detection of carbon-bearing molecules on a possible Hycean planet named K2-18b'.I was at an offline meeting when my colleagues showed screenshots of the relevant news in several WeChat groups that lam involved *** taking a quick glance at the spectra and their conclusion,I thought,"Wow!He(*** Nikku from Cambridge)took the first step toward finding what he predicted in advance!"

关键词： planet conclusion finding

The Wandering Earth II:A happy union between science and film

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The Innovation 2023年第2期4卷 3-4页

作者： Shu wang Ewing Luo School of Film Xiamen University No.422Siming South RoadXiamenFujian 361005China Joint Science Center for China Space Station Telescope National Astronomical ObservatoriesChinese Academy of SciencesA20 Datun RoadChaoyangBeijing 100101China G FilmRoom 3014-B-3Road Floor Qingnian Road(Trust Company Warehouse)Chaoyang DistrictBeijing 100123China

In 2023,during the Chinese Lunar New Year,a science fiction film from China called The Wandering Earth II was released globally and received an over-whelming response from *** just the first 3 days,it attracted over 20 million viewers *** film is set in a future world where the Sun is dying out and Earth is facing an impending apocalypse in just 100 *** of seeking refuge in spacecraft,mankind decides to take the planet with them on a journey out of the Solar System,driven by their longing for their beloved home,Earth.

关键词： Earth film union

猪肾动脉射频消融去神经术对内皮素1及其受体的影响

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中华实用诊断与治疗杂志 2019年第4期33卷 313-317页

作者：苏恩勇赵林蔚杨晓航朱彬彬王宪沛齐大屯张优王山高传玉郑州大学人民医院河南省人民医院心内科郑州450003 郑州市心血管病医院心血管内科 450001 河南省心血管流行病学研究中心郑州450003

目的探讨射频消融肾去神经(renal denervation, RDN)术对高脂饮食(high-fat diet, HFD)猪的内皮素1(endothelin-1, ET-1)及其受体的影响。方法健康雄性巴马小型猪15头,随机分为对照组、HFD组和HFD+RDN组各5头,对照组给予正常饮食,HFD组... 详细信息

目的探讨射频消融肾去神经(renal denervation, RDN)术对高脂饮食(high-fat diet, HFD)猪的内皮素1(endothelin-1, ET-1)及其受体的影响。方法健康雄性巴马小型猪15头,随机分为对照组、HFD组和HFD+RDN组各5头,对照组给予正常饮食,HFD组给予HFD,HFD+RDN组行双侧肾动脉射频消融RDN术,并给予HFD。6个月后,检测3组血清总胆固醇(total cholesterol, TC)、三酰甘油(triacylglycerol, TG)、高密度脂蛋白胆固醇(high-density lipoprotein cholesterol, HDL-C)、低密度脂蛋白胆固醇(low-density lipoprotein cholesterol, LDL-C)和血肌酐(serum creatinine, SCr)水平。采用ELISA法检测实验前、6个月后血浆及6个月后肾组织和肺组织肾素、血管紧张素Ⅱ(angiotensinⅡ, AngⅡ)、醛固酮(aldosterone, Ald)和ET-1水平,采用Western blot法检测6个月后肾组织与肺组织ET-1、内皮素A受体(endothelin A receptor, ET_AR)、内皮素B受体(endothelin B receptor, ET_BR)、内皮素转化酶1(endothelin converting enzyme 1, ECE1)蛋白相对表达量。结果 6个月后,HFD组体质量和血清TC水平高于对照组(P0.05),3组血清TG、LDL-C和SCr水平比较差异均无统计学意义(P>0.05);HFD组血浆和肾组织AngⅡ[(202.11±33.76)、(13.43±2.22)ng/L]和ET-1水平[(1.88±0.14)、(17.87±2.36)ng/L]均高于对照组[(128.43±12.45)、(8.72±2.17)ng/L,(1.51±0.08)、(12.80±2.93)ng/L]和HFD+RDN组[(160.95±19.50)、(10.71±1.17)ng/L,(1.66±0.11)、(14.62±0.94)ng/L](P0.05);HFD组肺组织ET-1水平[(0.54±0.09)ng/L]高于对照组[(0.39±0.09)ng/L]和HFD+RDN组[(0.41±0.06)ng/L](P0.05);HFD组肾组织和肺组织ECE1(0.54±0.11、0.63±0.12)、ET-1(0.59±0.10、0.58±0.06)和ET_AR蛋白相对表达量(0.59±0.10、0.36±0.10)均高于对照组[ECE1(0.28±0.08、0.28±0.06)、ET-1(0.13±0.02、0.29±0.08)、ET_AR (0.39±0.06、0.14±0.05)]和HFD+RDN组[ECE1(0.42±0.07、0.49±0.06)、ET-1(0.28±0.17、0.46±0.05)、ET_AR(0.48±0.03、0.17±0.06)](P0.05)。结论 RDN术可抑制HFD诱导猪的血浆、肾和肺组织中ET-1及其受体表达水平改变。

关键词：内皮素1 高脂饮食肾去神经术高血压内皮素受体猪

Subdomain-Specific Collapse of Denatured Staphylococcal Nuclease Revealed by Single Molecule Fluorescence Resonance Energy Transfer Measurements

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Subdomain-Specific Collapse of Denatured Staphylococcal Nucl...

An Arecibo follow-up study of seven pulsars discovered by Five-hundred-meter Aperture Spherical radio Telescope(FAST)

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作者： Chih-chen wang National Laboratory of Biomacromolecules Institute of BiophysicsChinese Academy of Sciences15 Datun Road

＜正＞By using single molecule fluorescence resonance energy transfer（smFRET）,the equilibrium denaturation of staphylococcal nuclease（SNase） induced by guanidinium hydrochloride（GdmCl） has been *** have characterized the collapse of the denatured chain and its relation to structure *** mutants,K28C/H124C and K28C/K97C,were constructed and labeled for

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Research in Astronomy and Astrophysics 2021年第10期21卷 97-107页

作者： Shen wang Wei-Wei Zhu Di Li Zhi-Chen Pan Pei wang James MCordes Shami Chatterjee Ju-Mei Yao Lei Qian You-Ling Yue Lei Zhang Ru-Shuang Zhao Shuang-Qiang wang Jia-Rui Niu Mao Yuan Chen-Chen Miao Xiao-Yao Xie Zhi-Jie Liu Xu-Hong Yu Shan-Ping You Ling-Qi Meng FAST Collaboration National Astronomical Observatories Chinese Academy of Sciences20A Datun RoadChaoyang DistrictBeijing 100101China College of Astronomy and Space Sciences University of Chinese Academy of SciencesBeijing 100049China NAOC-UKZN Computational Astrophysics Centre University of KwaZulu-NatalDurban 4000South Africa Department of Astronomy Cornell UniversityIthacaNY 14853USA Cornell Center for Astrophysics and Planetary Science Cornell UniversityIthacaNY 14853USA Xinjiang Astronomical Observatories Chinese Academy of Sciences150Science 1-StreetUrumqi 830011China Guizhou Normal University Guiyang 550001China

We present Arecibo 327 MHz confirmation and follow-up studies of seven new pulsars discovered by the Five-hundred-meter Aperture Spherical radio Telescope(FAST).These pulsars are discovered in a pilot program of the Commensal Radio Astronomy FAST Survey(CRAFTS)with the ultra-widebandwidth commissioning *** of them are normal pulsars and two are extreme nulling slow *** J2111+2132’s dispersion measure(DM:78.5 pc cm^(-3))is above the upper limits of the two Galactic free electron density models,NE2001 and YMW16,and PSR J2057+2133’s position is out of the Scutum-Crux Arm,making them uniquely useful for improving the Galactic free electron density model in their *** present a detailed single pulse analysis for the slow nulling *** show evidence that PSR J2323+1214’s main pulse component follows a non-Poisson distribution and marginal evidence for a sub-pulse-drift or recurrent period of 32.3±0.4 rotations from PSR J0539+*** discuss the implication of our finding to the pulsar radiation mechanism.

关键词： methods:observational pulsars:general stars:neutron

Identification of AtENT3 as the main transporter for uridine uptake in Arabidopsis roots

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Cell Research 2006年第4期16卷 377-388页

作者： Kun Ling Chen~(1,2,*) Min Xin Xu~(2,3,*) Guang Yong Li~(2,3,*) Hui Liang~2 Zong Liang Xia~(2,3) Xin Liu~2 Ji Shu Zhang~1 Ai Min Zhang~2 Dao Wen wang~2 ~1School of Life Sciences,Northwest Agricultural and Forestry University,Yangling 712100,China ~2Center for Plant Gene Research(Beijing)and the State Kev Laboratory of Plant Cell and Chromosome Engineering,Institute of Genetics and Developmental Biology,Chinese Academy of Sciences,datun Road,Chaovang District,Beijing 100101,China ~3Graduate School of the Chinese Academy of Sciences,Yuquan Road,Shijingshan District,Beijing 100039,China SchoolofLifeSciences NorthwestAgriculturalandForestryUniversityYangling712100China andtheStateKeyLaboratoryofPlantCellandChromosomeEngineering InstituteofGeneticsandDevelopmen

Previous studies have shown that Arabidopsis equilibrative nucleoside transporters （AtENTs） possess transport activitieswhen produced in yeast cells and are differentially expressed in Arabidopsis ***,we report further analysis onthe nucleoside transport activities and transcriptional patterns of AtENT *** recombinant proteins of AtENTs3,6,and 7,but not those of AtENTs 1,2,4,and 8,were found to transport thymidine with high *** to previ-ous suggestion that AtENT1 may not transport uridine,this work showed that recombinant AtENT1 was a pH-dependentand high-affinity transporter of *** grown on MS plates,the AtENT3 knockout plants were more tolerant tothe cytotoxic uridine analog 5-fluorouridine than wild-type plants and the knockout plants ofAtENT 1 or ***-sistent with this observation,the AtENT3 knockout line exhibited a significantly decreased ability to take up [3H]uridinevia the roots when compared with wild-type plants and the plants with mutated AtENT 1 or *** indicates thatAtENT3,but not AtENTs 1 and 6,is the main transporter for uridine uptake in Arabidopsis *** transcription ofAtENTs 1,3,4,6,7,and 8 was regulated in a complex manner during leaf development and *** contrast,thesix AtENT members were coordinately induced during seed *** work provides new information on thetransport properties of recombinant AtENT proteins and new clues for future studies of the in vivo transport activitiesand physiological functions of the different ENT proteins in Arabidopsis plants.

关键词： Arabidopsis equilibrative nucleoside transporter expression pattern nucleoside transport functional analysis

血栓抽吸术对急性STEMI患者QTc间期和预后的影响

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河南医学研究 2017年第12期26卷 2116-2119页

作者：杨曙艳李牧蔚刘伟利王宪沛张优齐大屯胡大一高传玉河南省胸科医院心电图室河南郑州450003 郑州大学人民医院心血管内科河南郑州450003 河南省心血管流行病学中心河南郑州450003

目的探讨血栓抽吸术对ST段抬高型心肌梗死(STEMI)患者QTc间期和预后的影响。方法选取86例采用EXPORT导管血栓抽吸术治疗的前壁STEMI患者作为血栓抽吸组,并选择同期连续没有使用EXPORT导管血栓抽吸术的80例前壁STEMI患者作为非血栓抽吸... 详细信息

目的探讨血栓抽吸术对ST段抬高型心肌梗死(STEMI)患者QTc间期和预后的影响。方法选取86例采用EXPORT导管血栓抽吸术治疗的前壁STEMI患者作为血栓抽吸组,并选择同期连续没有使用EXPORT导管血栓抽吸术的80例前壁STEMI患者作为非血栓抽吸组。对比分析两组STEMI患者TIMI血流分级,校正TIMI帧数,ST段抬高回落百分比,心电图QTc间期变化,血浆肌钙蛋白I峰值时间,左室舒张末内径(LVEDd),左室射血分数(LVEF)及临床预后。结果与非血栓抽吸组比较,血栓抽吸组QTc间期和肌钙蛋白峰值时间明显缩短,峰值明显下降(P<0.05);PCI结束时TIMI血流明显改善(P<0.05);住院期间恶性心律失常略有减少(P<0.05)。结论血栓抽吸术可缩短STEMI患者QTc间期,但对住院期间和PCI术后6个月的心血管预后无明显改善。

关键词： ST段抬高心肌梗死血栓抽吸 QTc间期预后

Temporal and spatial distribution characteristics in the natural plague foci of Chinese Mongolian gerbils based on spatial autocorrelation

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Infectious Diseases of Poverty 2017年第1期6卷 1090-1099页

作者： Hai-Wen Du Yong wang Da-Fang Zhuang Xiao-San Jiang State Key Laboratory of Resources and Environmental Information Systems Institute of Geographical Sciences and Natural Resources ResearchChinese Academy of Sciences11A Datun RoadChaoyang DistrictBeijing 100101China College of Resources and Environmental Science Nanjing Agricultural UniversityNo.6 Tongwei RoadNangjing 210095China

Background:The nest flea index of Meriones unguiculatus is a critical indicator for the prevention and control of plague,which can be used not only to detect the spatial and temporal distributions of Meriones unguiculatus,but also to reveal its cluster *** research detected the temporal and spatial distribution characteristics of the plague natural foci of Mongolian gerbils by body flea index from 2005 to 2014,in order to predict plague ***:Global spatial autocorrelation was used to describe the entire spatial distribution pattern of the body flea index in the natural plague foci of typical Chinese Mongolian *** and outlier analysis and hot spot analysis were also used to detect the intensity of clusters based on geographic information system *** quantity of *** nest fleas in the sentinel surveillance sites from 2005 to 2014 and host density data of the study area from 2005 to 2010 used in this study were provided by Chinese Center for Disease Control and ***:The epidemic focus regions of the Mongolian gerbils remain the same as the hot spot regions relating to the body flea *** clustering areas possess a similar pattern as the distribution pattern of the body flea index indicating that the transmission risk of plague is relatively *** terms of time series,the area of the epidemic focus gradually increased from 2005 to 2007,declined rapidly in 2008 and 2009,and then decreased slowly and began trending towards stability from 2009 to *** the spatial change,the epidemic focus regions began moving northward from the southwest epidemic focus of the Mongolian gerbils from 2005 to 2007,and then moved from north to south in 2007 and ***:The body flea index of Chinese gerbil foci reveals significant spatial and temporal aggregation characteristics through the employing of spatial *** diversity of temporary and spatial distribution is mainly affected by seasonal vari

关键词： Geographic information system Temporal and spatial distribution Spatial autocorrelation Moran’s I Body fleas Plague natural focus of Mongolian gerbils China

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An Introduction to the Chinese High-Resolution Earth Observation System:Gaofen-1~7 Civilian Satellites

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Journal of Remote Sensing 2022年第1期2022卷 244-257页

作者： Liangfu Chen Husi Letu Meng Fan Huazhe Shang Jinhua Tao Laixiong Wu Ying Zhang Chao Yu Jianbin Gu Ning Zhang Jin Hong Zhongting wang Tianyu Zhang State Key Laboratory of Remote Sensing Science The Aerospace Information Research InstituteChinese Academy of Sciences(CAS)Datun Road No.20(North)Beijing 100101China University of Chinese Academy of Sciences(UCAS) Beijing 100101China Remote Sensing Application Center Ministry of Housing and Urban-Rural Development of the People’s Republic of ChinaSanlihe Road No.9 Beijing 100835China Key Laboratory of Optical Calibration and Characterization of Chinese Academy of Science Anhui Institute of Optics and Fine MechanicsChinese Academy of SciencesHefei 230031China Center for Satellite Application on Ecology and Environment Ministry of Ecology and EnvironmentBeijing 100006China

The Chinese High-resolution Earth Observation System(CHEOS)program has successfully launched 7 civilian satellites since *** satellites are named by Gaofen(meaning high resolution in Chinese,hereafter noted as GF).To combine the advantages of high temporal and comparably high spatial resolution,diverse sensors are deployed to each ***-1 and GF-6 carry both high-resolution cameras(2m resolution panchromatic and 8m resolution multispectral camera),providing high spatial imaging for land use monitoring;GF-3 is equipped with a C-band multipolarization synthetic aperture radar with a spatial resolution of up to 1 meter,mostly monitoring marine targets;GF-5 carried 6 sensors including hyperspectral camera and directional polarization camera,dedicated to environmental remote sensing and climate research,such as aerosol,clouds,and greenhouse gas monitoring;and GF-7 laser altimeter system payload enables a three-dimensional surveying and mapping of natural resource and land surveying,facilitating the accumulation of basic geographic *** study provides an overview of GF civilian series satellites,especially their missions,sensors,and applications.

关键词： payload Earth surveying