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我国基本养老保险基金征缴的策略性互动行为分析

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保险研究 2024年第2期 96-110页

作者：王雪辉上海对外经贸大学会展与传播学院

基本养老金作为退休职工的主要收入来源,是实现“老有所养”美好生活所需的经济基础和重要保障。本文基于两区制空间杜宾模型探讨了我国地方政府在基本养老保险基金征缴方面的差异化策略性互动行为。研究发现:随着基本养老保险基金收支... 详细信息

基本养老金作为退休职工的主要收入来源,是实现“老有所养”美好生活所需的经济基础和重要保障。本文基于两区制空间杜宾模型探讨了我国地方政府在基本养老保险基金征缴方面的差异化策略性互动行为。研究发现:随着基本养老保险基金收支压力提高,我国地方政府养老保险基金实际征缴率呈“倒U型”变化趋势;地方政府对基本养老保险基金征缴的策略性互动存在于地理邻近与经济邻近的地区间,受软、硬预算约束的影响,地理邻近地区间表现为“模仿行为”,经济邻近地区间表现为“逐顶竞争”;基金征缴的策略性互动行为存在显著的时间阶段性与区域异质性;随着养老保险基金收支压力的提高,地方政府对养老保险基金征缴的策略性互动增强。

关键词：基本养老金策略性互动软预算约束两区制空间杜宾模型

基于Kriging模型的船舶主机隔离系统抗冲击优化

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哈尔滨工程大学学报 2024年第7期45卷 1266-1272页

作者：王茀凡赵华讯王爽郭君哈尔滨工程大学船舶工程学院黑龙江哈尔滨150001 中海石油(中国)有限公司海南分公司海南海口570100

为了提高系统的抗冲击性能和优化效率,本文以限位隔离系统的刚度阻尼等7个参数为设计变量,以系统冲击响应中的相对位移响应和绝对加速度响最大峰值为响应值建立Kriging代理模型。通过NSGA-II多目标优化算法对构建的代理模型进行多目标优... 详细信息

为了提高系统的抗冲击性能和优化效率,本文以限位隔离系统的刚度阻尼等7个参数为设计变量,以系统冲击响应中的相对位移响应和绝对加速度响最大峰值为响应值建立Kriging代理模型。通过NSGA-II多目标优化算法对构建的代理模型进行多目标优化,优化目标为相对位移响应和绝对加速度响最大峰值两者和的最小值。与初始方案相比,优化后系统相对位移响应降低了27.139%,绝对加速度响应降低了37.846%。结果表明:建立的代理模型对隔离系统的冲击响应有较精确的预报作用,优化后船舶主机隔离系统的抗冲击得到明显提高。

关键词：船舶主机隔离系统多目标优化 Kriging代理模型冲击响应试验设计最优拉丁方 NSGA-Ⅱ算法

Surface plasmon-coupled radiative heat transfer between graphene-covered magnetic Weyl semimetals

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Science China Technological Sciences 2024年第11期67卷 3405-3412页

作者： SONG JinLin YAO XinJie JIN Lin CHEN Lei zhao HaiLong CHENG Qiang School of Electrical and Information Engineering Wuhan Institute of Technology State Key Laboratory of Coal Combustion School of Energy and Power EngineeringHuazhong University of Science and Technology

Weyl semimetals(WSMs) have recently attracted considerable research attention because of their remarkable optical and electrical properties. In this study, we investigate the near-field radiative heat transfer(NFRHT) between graphene-covered Weyl slabs, particularly focusing on the supported coupled surface plasmon polaritons(SPPs). Unlike bare Weyl slabs where the epsilon-near-zero(ENZ) effect contributes the most to the NFRHT, adding a monolayer graphene sheet yields coupled SPPs, i.e.,the coupling of graphene SPPs(GSPPs) and Weyl SPPs(WSPPs), which dominates the NFRHT. The graphene sheet greatly suppresses the ENZ effect by compressing the parallel wavevector, thereby enabling the heat transfer coefficient(HTC) to be significantly changed. Further, for the graphene-covered magnetic Weyl slab configuration, an increase in the number of Weyl nodes suppresses the SPP coupling and ENZ effect, thereby weakening the NFRHT with a regulation ratio of 4.4 whereas an increase in the Fermi level slightly influences the NFRHT. Several typical heterostructures are also proposed for comparison, and results show that a mono-cell structure has the largest total HTC. Our findings will facilitate the understanding of surface plasmon-coupled radiative heat transfer and enable opportunities in energy harvesting and thermal management at the nanoscale based on WSM-based systems.

关键词： near-field radiative heat transfer Weyl semimetal surface plasmon polariton epsilon-near-zero graphene

DIA-based proteome profiling with PRM verification reveals the involvement of ER-associated protein processing in pollen abortion in Ogura CMS cabbage

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Horticultural Plant Journal 2024年第3期10卷 755-770页

作者： Peiwen wang Lin Zhu Ziheng Li Mozhen Cheng Xiuling Chen Aoxue wang Chao wang Xiaoxuan Zhang Key Laboratory of Biology and Genetic Improvement of Horticultural Crops(Northeast Region) Ministry of Agriculture and Rural AffairsNortheast Agricultural UniversityHarbinHeilongjiang 150030China College of Horticulture and Landscape Architecture Northeast Agricultural UniversityHarbinHeilongjiang 150030China

Ogura cytoplasmic male sterility(Ogura CMS)is extensively applied in hybrid seed production in cruciferous ***,the posttranscriptional molecular basis of Ogura CMS in cruciferous crops remains ***,a data-independent acquisition-based proteomic approach coupled with a parallel reaction monitoring-based targeted proteomic assay was used to analyze the proteome dynamics of Ogura CMS cabbage line RM and its maintainer line RF during floral bud development to obtain insights into the mechanism underlying Ogura CMS in cruciferous crops.A total of 9162 proteins corresponding to 61464 peptides were identified in RM and RF floral *** proteomic fluctuation of RM was weaker than that of *** in protein expression between RM and RF gradually enlarged with floral bud *** continually up-regulated and eight continually down-regulated proteins were found in RM relative to RF throughout floral bud *** expressed proteins between RM and RF during floral bud development were implicated in the endoplasmic reticulum(ER)-associated protein processing pathway,in which most of them exhibited down-regulated expression in *** data suggest that ER-associated protein processing may be involved in pollen abortion in Ogura CMS cabbage by inhibiting the expression of critical *** findings not only deepen the understanding of the molecular mechanisms of Ogura CMS in cruciferous crops but also provide better guidance for applying Ogura CMS in the hybrid breeding of cruciferous crops.

关键词： Ogura cytoplasmic male sterility(Ogura CMS) Cabbage Data-independent acquisition(DIA) Parallel reaction monitoring(PRM) Pollen development

Efficacy and safety of first-line treatment for metastatic triple-negative breast cancer:A network meta-analysis

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Cancer Pathogenesis and Therapy 2024年第2期2卷 81-90页

作者： Mingqiang Shi Zhoujuan Li Guoshuang Shen Tianzhuo wang Jinming Li Miaozhou wang Zhen Liu Fuxing zhao Dengfeng Ren Jiuda zhao Breast Disease Diagnosis and Treatment Center of Affiliated Hospital of Qinghai University&Affiliated Cancer Hospital of Qinghai UniversityXiningQinghai 810000China

Background:Metastatic triple-negative breast cancer(mTNBC)is an aggressive histological subtype with poor *** first-line treatments are currently available for *** study conducted a network meta-analysis to compare these first-line regimens and to determine the regimen with the best ***:A systematic search of PubMed,EMBASE,the Cochrane Central Register of Controlled Bases,and mi-nutes of major conferences was ***-free survival(PFS),overall survival(OS),and objective response rate(ORR)were analyzed via network meta-analysis using the R software(R Core Team,Vienna,Austria).The efficacy of the treatment regimens was compared using hazard ratios and 95%confidence ***:A total of 29 randomized controlled trials involving 4607 patients were *** ranking was based on the surface under the cumulative ranking *** meta-analysis results showed that cisplatin combined with nab-paclitaxel or paclitaxel was superior to docetaxel plus capecitabine in terms of PFS and *** programmed death-ligand 1(PD-L1)and breast cancer susceptibility gene(BRCA)mutation-positive tumors,atezolizumab/pembrolizumab combined with nab-paclitaxel and talazoparib was superior to docetaxel plus *** significant difference was observed among the treatments in ***,diarrhea,and fatigue were common serious adverse ***:Cisplatin combined with nab-paclitaxel or paclitaxel is the preferred first-line treatment for *** PD-L1 and BRCA mutation-positive tumors,atezolizumab/pembrolizumab combined with nab-paclitaxel and talazoparib is an effective treatment option,Neutropenia,diarrhea,and fatigue are frequently occurring serious adverseevents.

关键词： Metastatictriple-negativebreast cancer First-line treatment Chemotherapy Immune-checkpoint inhibitors Poly(ADP-Ribose)polymerase inhibitors AKT inhibitor Networkmeta-analysis

改进VSG和下垂控制双驱动的孤岛微电网稳定运行控制策略

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电力系统及其自动化学报 2024年第10期36卷 117-126页

作者：赵辉王涛胡平韩璟琳刘洋国网河北省电力有限公司石家庄050081 国网河北省电力有限公司经济技术研究院石家庄050021

针对孤岛微电网频率和电压在传统控制方式下难以保持稳定的问题,提出一种改进虚拟同步发电机和下垂控制双驱动的稳定运行控制策略。首先,在传统下垂控制中引入耦合补偿和虚拟阻抗,提出一种改进下垂控制策略;将辅助惯性加入虚拟同步发电... 详细信息

针对孤岛微电网频率和电压在传统控制方式下难以保持稳定的问题,提出一种改进虚拟同步发电机和下垂控制双驱动的稳定运行控制策略。首先,在传统下垂控制中引入耦合补偿和虚拟阻抗,提出一种改进下垂控制策略;将辅助惯性加入虚拟同步发电机调速单元中提供惯性响应,并结合有功功率频率环路附加功率提出一种改进虚拟同步发电机控制方法;然后,基于电压同步控制器和双环控制器提出两种改进控制方法优势互补的暂态稳定性综合控制策略;最后,通过仿真和实验分析结果验证了本文所提控制方法和切换策略在负荷大扰动情况下的有效性,为后续微电网稳定运行控制提供借鉴。

关键词：暂态稳定性虚拟阻抗孤岛型微电网下垂控制虚拟同步发电机

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Inhalable nanoparticles with enhanced cuproptosis and cGAS-STING activation for synergistic lung metastasis immunotherapy

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Acta Pharmaceutica Sinica B 2024年第8期14卷 3697-3710页

作者： Chongzheng Yan Huaiyou Lv Yafei Feng Yuhan Li Zhongxi zhao Department of Pharmaceutics Key Laboratory of Chemical Biology of Ministry of EducationSchool of Pharmaceutical SciencesCheelloo College of MedicineShandong UniversityJinan 250012China Key University Laboratory of Pharmaceutics&Drug Delivery Systems of Shandong Province School of Pharmaceutical SciencesCheeloo College of MedicineShandong UniversityJinan 250012China Department of Pharmacy Yantai Yuhuangding Hospital Affiliated to Qingdao UniversityYantai 264001China

Due to the insufficient Cu^(+)accumulation,Cu^(+)efflux mechanism,and highly immunosuppressive tumor microenvironment(TME)in lung metastasis,the cuproptosis efficacy is ***,an inhalable nanodevice(CLDCu)is constructed to successfully overcome the drawbacks of *** consists of a Cu^(2+)-chitosan shell and low molecular weight heparin-tocopherol succinate(LMWH-TOS,LT)core with disulfiram(DSF)*** prepared CLDCu can be inhaled and accumulate in large amounts in lung lesions(63.6%)with 56.5 times higher than intravenous *** tumor cells,the mild acidity triggers the co-release of DSF and Cu2+,thus generating bis(diethyldithiocarbamate)-copper(CuET)to block Cu^(+)efflux protein ATP7B and forming toxic Cu^(+),leading to enhanced ***,the released chitosan cooperates with CLDCu-induced cuproptosis to activate stimulator of interferon genes(STING)pathway,which significantly potentiates dendritic cells(DCs)maturation,as wells as evokes innate and adaptive *** lung metastatic mice model,CLDCu is found to induce cuproptosis and reverse the immunosuppressive TME by inhalation ***,CLDCu combined with anti-programmed cell death protein ligand-1 antibody(aPD-L1)provokes stronger antitumor ***,nanomedicine that combines cuproptosis with STING activation is a novel strategy for tumor immunotherapy.

关键词： Cuproptosis cGAS-STING activation Disulfiram Inhalation administration Tumor microenvironment PD-L1 checkpoint blockade Lung metastasis Immunotherapy

基于引气封油方式的轴承腔密封间隙油气两相泄漏流动特性数值与试验研究

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机械工程学报 2024年第3期60卷 214-225页

作者：郭金道赵欢王平孙丹王双沈阳航空航天大学航空发动机学院沈阳110136 沈阳航空航天大学辽宁省航空推进系统先进测试技术重点实验室沈阳110136 中国航发四川燃气涡轮研究院成都610000

轴承腔滑油泄漏直接影响航空发动机的安全性,而现有研究缺乏引气条件对轴承腔滑油密封性能的探索。设计搭建轴承腔密封间隙油气两相泄漏流动特性试验装置,建立轴承腔油气两相泄漏流动特性数值求解模型,在数值与试验结果相互验证的基础上... 详细信息

轴承腔滑油泄漏直接影响航空发动机的安全性,而现有研究缺乏引气条件对轴承腔滑油密封性能的探索。设计搭建轴承腔密封间隙油气两相泄漏流动特性试验装置,建立轴承腔油气两相泄漏流动特性数值求解模型,在数值与试验结果相互验证的基础上,研究轴承腔密封间隙油气两相分布状态与临界封油特性。研究表明:供气压强高于临界封油气压时,滑油与封油气体在油腔内混合形成复杂的油气两相状态,滑油油位越高,油气两相混合区域越大;供气压强低于临界封油气压时,滑油流入密封间隙,油气交界面状态呈现波状或条状,滑油流入气腔后首先呈现股状下流,而后呈膜状渗流。密封间隙由0.05 mm增加至0.20 mm,临界封油气压增加221.5%;滑油油位由30 mm增至120 mm,临界封油气压增加129.2%。滑油油位通过影响滑油加速度、密封间隙通过影响滑油加速度和节流效应对滑油泄漏流动产生影响。研究内容为轴承腔密封间隙泄漏流动特性分析与临界封油气压判定提供理论依据。

关键词：轴承腔引气封油油气两相流泄漏流动临界封油气压

CO2 electrolysis to formic acid for carbon neutralization

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Green Energy & Environment 2024年第9期9卷 1333-1335页

作者： Kezhen Qi Shu-yuan Liu Yingjie Zhang hui Zhang Vadim Popkov Oksana Almjasheva College of Pharmacy Dali University College of Agriculture and Biological Science Dali University School of Arts Minnan Normal University Hydrogen Energy Laboratory Ioffe Institute Department of Physical Chemistry Saint Petersburg Electrotechnical University “LETI”

To avoid carbonate precipitation for CO2electrolysis,developing CO2conversion in an acid electrolyte is viewed as an ultimately challenging *** Nature,Xia et *** explored a proton-exchange membrane system for reducing CO2to formic acid with a Pb±Pb SO4composite catalyst derived from waste lead-acid batteries based on the lattice carbon activation *** to 93%Faradaic efficiency was realized when formic acid was produced by this technology.

关键词： CO 2 electrolysis Proton-exchange membrane system Faradaic efficiency Carbon neutralization CO 2 reduction reaction