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Microwave-accelerated direct regeneration of LiCoO_(2)cathodes for Li-ion batteries

Science China Chemistry 2024年第7期67卷 2181-2189页

作者： Xueshan Hu Yun-Chao Yin Chao Li Lihui Zhou Lin Yang Yitian Feng Daxian Zuo Chenhui Ning Das Soham sheng Dai Longbin Qiu Lin Zeng Haw Jiunn Woo Jiayu wan Future Battery Research Center Global Institute of Future TechnologyShanghai Jiao Tong UniversityShanghai 200240China Department of Mechanical and Energy Engineering Southern University of Science and TechnologyShenzhen 518055China Centre for Ionics University of Malaya Department of PhysicsFaculty of ScienceUniversity of MalayaKuala Lumpur 50603Malaysia Key Laboratory for Advanced Materials and Feringa Nobel Prize Scientist Joint Research Center School of Chemistry and Molecular EngineeringEast China University of Science and TechnologyShanghai 200237China Department of Natural and Applied Sciences Duke Kunshan UniversityKunshan 215316China

Recycling spent lithium-ion batteries is integral to today's low-carbon environmental protection *** concept of direct regeneration,acknowledged for its environmental sustainability,economic viability,and consistent performance of recycled materials,is gaining *** study presents an efficient and nondestructive approach by utilizing an ultrafast microwave technology to directly regenerate spent lithium cobaltate(LCO)cathode *** contrast to conventional furnacebased processes,this method significantly reduces the regeneration *** subjecting the spent LCO mixed with lithium sources to three microwave heating cycles(at approximately 1,350 K),LCO regeneration is achieved,yielding a specific capacity of 140.8 mAh g^(-1)(0.2 C)with a robust cycle *** further environmental and economic benefits,the ultrafast microwave technology holds scientific promise for directly regenerating cathode materials,while establishing competitiveness for industrial applications.

关键词： battery recycling spent lithium cobaltate microwave directly regeneration cathode materials

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Transforming growth factor-β1 and vascular endothelial growth factor levels in senile acute myeloid leukemia and correlation with prognosis

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World Journal of Clinical Cases 2024年第20期12卷 4121-4129页

作者： wan Li sheng-Yu Ma Hui-Ying Zhao Department of Hematology Suzhou Hospital of Anhui Medical UniversitySuzhou 234000Anhui ProvinceChina

BACKGROUND Acute myeloid leukemia(AML)is a disease in which immature hematopoietic cells accumulate in the bone marrow and continuously expand,inhibiting *** treatment and prognosis of this disease have always been *** To investigate the correlation between vascular endothelial growth factor(VEGF)and transforming growth factor-β1(TGFβ1)expression and prognosis in older adults with *** This study enrolled 80 patients with AML(AML group),including 36 with complete response(AML-CR),23 with partial response(AML-PR),and 21 with no response(AML-NR).The expression levels of VEGF and TGFβ1 were detected by reverse transcription polymerase chain reaction in bone marrow mononuclear cells isolated from 56 healthy ***-Meier analysis was performed to assess overall survival(OS)and progression-or disease-free survival(DFS).Prognostic risk factors were analyzed using a Cox proportional hazards *** The AML group showed a VEGF level of 2.68±*** expression was lower in patients with AML-CR than those with AML-PR or AML-NR(P<0.05).TGFβ1 expression in the AML group was 0.33±*** with AML-CR showed a higher TGFβ1 expression than those with AML-PR or AML-NR(P<0.05).VEGF and TGFβ1 expression in patients with AML was significantly correlated with the counts of leukocytes,platelets,hemoglobin,and peripheral blood immature cells(P<0.05);Kaplan-Meier survival analysis revealed that patients with high TGFβ1 expression had better OS and DFS than those with low TGFβ1 expression(P<0.05),whereas patients with low VEGF levels showed better OS and DFS than those with high VEGF levels(P<0.05).VEGF,TGFβ1,and platelet count were identified by the Cox proportional hazards model as independent risk factors for OS(P<0.05),while VEGF,TGFβ1,and white blood cell count were independent risk factors for DFS(P<0.05).CONCLUSION Decreased VEGF expression and increased TGFβ1 expression in patients with AML provide valuable references for det

关键词： Acute myeloid leukemia Transforming growth factor-β1 Vascular endothelial growth factor Expression level Prognostic correlation

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Plasma metabolites and risk of myocardial infarction:a bidirectional Mendelian randomization study

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Journal of Geriatric Cardiology 2024年第2期21卷 219-231页

作者： Dong-Hua LI Qiang WU Jing-sheng LAN Shuo CHEN You-Yi HUANG Lan-Jin WU Zhi-Qing QIN Ying HUANG wan-Zhong HUANG Ting ZENG Xin HAO Hua-Bin SU Qiang SU Department of Cardiovascular Medicine Minzu Hospital of Guangxi Zhuang Autonomous RegionGuangxiChina Senior Department of Cardiology the Sixth Medical CenterChinese PLA General HospitalBeijingChina Library of Graduate School Chinese PLA General HospitalBeijingChina Department of Cardiology Jiangbin Hospital of Guangxi Zhuang Autonomous RegionGuangxiChina Health Management Institute the Second Medical CenterChinese PLA General HospitalBeijingChina

BACKGROUND Myocardial infarction(MI)is a critical cardiovascular event with multifaceted etiology,involving several genetic and environmental *** is essential to understand the function of plasma metabolites in the development of MI and unravel its complex *** This study employed a bidirectional Mendelian randomization(MR)approach to investigate the causal relationships between plasma metabolites and MI *** used genetic instruments as proxies for plasma metabolites and MI and conducted MR analyses in both directions to assess the impact of metabolites on MI risk and vice *** addition,the large-scale genome-wide association studies datasets was used to identify genetic variants associated with plasma metabolite(1400 metabolites)and MI(20,917 individuals with MI and 440,906 individuals without MI)*** variance weighted was the primary method for estimating causal *** estimates are expressed as beta coefficients or odds ratio(OR)with 95%*** We identified 14 plasma metabolites associated with the occurrence of MI(P<0.05),among which 8 plasma metabolites[propionylglycine levels(OR=0.922,95%CI:0.881–0.965,P<0.001),gamma-glutamylglycine levels(OR=0.903,95%CI:0.861–0.948,P<0.001),hexadecanedioate(C16-DC)levels(OR=0.941,95%CI:0.911–0.973,P<0.001),pentose acid levels(OR=0.923,95%CI:0.877–0.972,P=0.002),X-24546 levels(OR=0.936,95%CI:0.902–0.971,P<0.001),glycine levels(OR=0.936,95%CI:0.909–0.964,P<0.001),glycine to serine ratio(OR=0.930,95%CI:0.888–0.974,P=0.002),and mannose to trans-4-hydroxyproline ratio(OR=0.912,95%CI:0.869–0.958,P<0.001)]were correlated with a decreased risk of MI,whereas the remaining 6 plasma metabolites[1-palmitoyl-2-arachidonoyl-GPE(16:0/20:4)levels(OR=1.051,95%CI:1.018–1.084,P=0.002),behenoyl dihydrosphingomyelin(d18:0/22:0)levels(OR=1.076,95%CI:1.027–1.128,P=0.002),1-stearoyl-2-docosahexaenoyl-GPE(18:0/22:6)levels(OR=1.067,95%CI:1.027–1.109,P=0.001),alpha-ketobutyrate levels(OR=1.108,95%

关键词： infarction alterations diagnosis

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OsPRMT6a-mediated arginine methylation of OsJAZ1 regulates jasmonate signaling and spikelet development in rice

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Molecular Plant 2024年第6期17卷 900-919页

作者： Kun Dong Fuqing Wu Siqi Cheng Shuai Li Feng Zhang Xinxin Xing Xin Jin sheng Luo Miao Feng Rong Miao Yanqi Chang Shuang Zhang Xiaoman You Peiran wang Xin Zhang Cailin Lei Yulong Ren Shanshan Zhu Xiuping Guo Chuanyin Wu Dong-Lei Yang Qibing Lin Zhijun Cheng Jianmin wan State Key Laboratory of Crop Gene Resources and Breeding National Key Facility for Crop Gene Resources and Genetic ImprovementInstitute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China State Key Laboratory for Crop Genetics and Germplasm Enhancement Nanjing Agricultural UniversityNanjing 210095China

Although both protein arginine methylation(PRMT)and jasmonate(JA)signaling are crucial for regulating plant development,the relationship between these processes in the control of spikelet development remains *** this study,we used the CRISPR/Cas9 technology to generate two OsPRMT6a loss-of-function mutants that exhibit various abnormal spikelet ***,we found that OsPRMT6a can methylate arginine residues in JA signal repressors OsJAZ1 and *** showed that arginine methylation of OsJAZ1 enhances the binding affinity of OsJAZ1 with the JA receptors OsCOI1a and OsCOI1b in the presence of JAs,thereby promoting the ubiquitination of OsJAZ1 by the SCF^(OsCOI1a/OsCOI1b) complex and degradation via the 26S *** process ultimately releases OsMYC2,a core transcriptional regulator in the JA signaling pathway,to activate or repress JA-responsive genes,thereby maintaining normal plant(spikelet)***,in the osprmt6a-1 mutant,reduced arginine methylation of OsJAZ1 impaires the interaction between OsJAZ1 and OsCOI1a/OsCOI1b in the presence of *** a result,OsJAZ1 proteins become more stable,repressing JA responses,thus causing the formation of abnormal spikelet ***,we discovered that JA signaling reduces the OsPRMT6a mRNA level in an OsMYC2-dependent manner,thereby establishing a negative feedback loop to balance JA *** further found that OsPRMT6a-mediated arginine methylation of OsJAZ1 likely serves as a switch to tune JA signaling to maintain normal spikelet development under harsh environmental conditions such as high ***,our study establishes a direct molecular link between arginine methylation and JA signaling in rice.

关键词： protein arginine methylation jasmonate signaling negative feedback loop spikelet development adaptation to heat stress rice

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整合素α6靶向自组装促凋亡纳米多肽对中枢神经系统急性淋巴细胞白血病的靶向治疗

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Engineering 2024年第4期35卷 226-240页

作者： Jia-Cong Ye wan-Qiong Li Mei-Ling Chen Qian-Kun Shi Hua wang Xin-Ling Li Ying-He Li Jie Yang Qiao-Li wang Fang Hu Yan-Feng Gao Shu-Wen Liu Mu-sheng Zeng Guo-Kai Feng Guangdong Provincial Key Laboratory of New Drug Screening&NMPA Key Laboratory of Drug Metabolism Research and Evaluation School of Pharmaceutical SciencesSouthern Medical UniversityGuangzhou 510515China State Key Laboratory of Oncology in South China&Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy Guangdong Provincial Clinical Research Center for CancerSun Yat-sen University Cancer CenterGuangzhou 510060China School of Pharmaceutical Sciences(Shenzhen) Shenzhen Campus of Sun Yat-sen UniversityShenzhen 518107China Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering Biomaterials Research CenterSchool of Biomedical EngineeringSouthern Medical UniversityGuangzhou 510515China State Key Laboratory of Organ Failure Research Guangdong Provincial Institute of NephrologySouthern Medical UniversityGuangzhou 510515China

There is currently no effective targeted therapeutic strategy for the treatment of central nervous system acute lymphoblastic leukemia(CNS-ALL).Integrinα6 is considered a potential target for CNS-ALL diagnosis and therapy because of its role in promoting CNS-ALL disease *** targeted peptide D(RWYD)(abbreviated RD),with nanomolar affinity to integrinα6 was identified by peptide scanning techniques such as alanine scanning,truncation,and ***,we developed a therapeutic nanoparticle based on the integrinα6-targeted peptide for treating *** self-assembled proapoptotic nanopeptide_(D)(RWYD)-_(D)(KLAKLAK)_(2)-G_(D)(FFY)(abbreviated RD-KLA-Gffy)contains the integrinα6-targeted peptide RD,the well-known proapoptotic peptide_(D)(KLAKLAK)_(2)(abbreviated KLA),and the self-assembling tetrapeptide GD(FFY)(abbreviated Gffy).The functional mechanism of RD-KLA-Gffy is clarified using different *** results demonstrate that RD-KLA-Gffy is highly enriched in CNS-ALL lesions and induces tumor cell apoptosis,thus reducing CNS-ALL disease burden and prolonging the survival of CNS-ALL mice without obvious ***,the combined use of RD-KLA-Gffy and methotrexate(MTX)shows a potent antitumor effect in treating CNS-ALL,indicating that RD-KLA-Gffy plays an important role in suppressing CNS-ALL progression either as a single agent or in combination with MTX,which shows promise for application in CNS-ALL therapy.

关键词： Central nervous system acute lymphoblastic leukemia Integrinα6 Targeted peptide Proapoptotic Nanopeptide

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Effect of Gs-Rb1 on EcoG of sleep and the spatial memory recalling at initial stage of awaking in rats

Effect of Gs-Rb1 on EcoG of sleep and the spatial memory rec...

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中国神经科学学会第四次会员代表大会暨第七届全国学术会议

作者： Tao XIONG,wan-Li wang,sheng-Jun DAI,Zi-Li YOU Laboratory of Molecular Neurobiology,College of Life Science and Technology,University of Electronic Science and Technology of China,Chengdu 610054,China

＜正＞Objective Ginseng,has been used in China and other countries over 2 000 years,has multi-modulations on Central Nervous System,（CNS） as "adaptogen".It was showed Ginsenoside Rbl（Gs-Rbl,25-hydroxy-ginsenoside-Rh1, 40 mg/kg）,one of main components isolated from ginseng,significantly decreased the free-movement-times of mice in our previous *** intended in this experiment to investigate the effect of Gs-Rb1（ip） on electrocorticography（EcoG）, learning and memory of rats,and to analyze the effective pattern of Gs-Rbl on the sleep process and the initial stage of awaking of ***（1） EcoG of sleep recording:Sixteen male rats（250-300 g） were randomly divided into 2 groups: Control for EcoG（CE） and Gs-Rb1 treated for EcoG group（GTE）,8 rats in each *** rat was set the stainless steel screws on the cerebral cortex through the skull（Coordinate of Record point:A/P -0.8,M/L +3.0;Coordinate of reference point:A/P +2.7,M/L -3.0）.The baseline EcoG including sleep-status and waking-status was recorded a week after the *** group rats were administrated（i.p.） Gs-Rbl at 40 mg/kg per day for 3 d from day 7 to day 9 after the electrodes were *** group rats were accordingly administrated（i.p.） with equal volume of normal solution（NS）. The EcoGs were recorded on day *** data of EcoG were processed off-line,with the sampling frequency of 200 Hz;the power spectral density（PSD） of delta,theta,alpha and beta were measured during the paradoxical sleep（PS） and slow wave sleep（SWS） of each rat.（2） Morris water maze test:Sixteen male rats（250-300 g） were randomly divided into two groups:Control group（C） and Gs-Rb1 treated group（GT）,each group with 8 *** group rats were administrated （i.p.） Gs-Rb1 at 40 mg/kg per day for 3 d from day 6 to day 8 and C group rats were accordingly administrated（i.p.） with equal volume of *** rats were trained respectively with Morris water maze（place navigation） for the sequential 5 d. Three days later,the spatial pr

关键词： Gs-Rb1 EcoG Morris water maze test sleep spatial memory

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2株共栖菌对铜绿微囊藻休眠体复苏的影响

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中国环境科学 2024年第8期44卷 4366-4379页

作者：邹万生莫平王智刘良国湖南文理学院生命与环境科学学院水产生物资源及环境生态湖南省工程研究中心湖南常德415000 湖南师范大学生命科学学院湖南长沙410000

为探讨水生共栖菌H1(Sphingobacterium kitahiroshimense 10C^(T))与H2(Bacillus zhangzhouensis DW5-4^(T))对铜绿微囊藻休眠体(DMCs)复苏的联合作用,将菌株H1、H2按不同菌浓度比(菌比)与DMCs用沉积物混匀包埋,以无菌组为对照,在温度15和25℃、光照强度15μmol/(m^(2)⋅s)和光暗比10h:14h条件下进行室内复苏实验,并结合室内实验结果开展野外实验.实验结果表明,低菌比(≤3)时,菌组DMCs可溶性胞外多糖(SPS)浓度显著下降,固着性胞外多糖(CPS)与DMCs光合效率(Fv/Fm)无显著变化(P>0.05),SPS下降不影响Fv/Fm,菌群通过泌出3种代谢产物显著提升DMCs复苏率.菌比提高(≥5)时,菌组DMCs的SPS和CPS浓度均显著下降,其Fv/Fm也显著下降(P<0.05),CPS浓度下降抑制了DMCs光合效率,高菌比菌群通过降低DMCs的光合效率和泌出2种有效抑制DMCs复苏的代谢产物协同降低DMCs复苏率(纯代谢产物作用下的DMCs复苏率高于同条件下菌组复苏率).野外定性实验证实了菌比显著影响DMCs复苏率,实验结果为进一步利用微生物制剂抑控DMCs复苏提供理论依据.

关键词：铜绿微囊藻光合效率水生细菌胞外多糖抗氧化酶

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超低场磁共振膝关节正交接收线圈设计

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电工技术学报 2024年第7期39卷 1923-1931页

作者：万裁何为沈晟徐征重庆大学电气工程学院重庆400044 麻省总医院Athinoula A.Martinos生物医学成像中心美国马萨诸塞州02114

射频接收线圈是磁共振成像(MRI)系统中的关键部件,用于检测变化的磁场,其性能直接影响图像的质量。超低场MRI射频接收线圈工作在较低频率,其阻抗特性不同于传统临床MRI射频接收线圈。理论上正交接收线圈比单通道线圈的信噪比(SNR)可以提... 详细信息

射频接收线圈是磁共振成像(MRI)系统中的关键部件,用于检测变化的磁场,其性能直接影响图像的质量。超低场MRI射频接收线圈工作在较低频率,其阻抗特性不同于传统临床MRI射频接收线圈。理论上正交接收线圈比单通道线圈的信噪比(SNR)可以提高41%。而与阵列线圈相比,正交接收线圈可以用更低的成本与设计复杂度达到很好的成像效果。因此该文研究了一种用于超低场MRI(50.4 mT)系统的膝关节正交接收线圈,它由鞍形线圈和亥姆霍兹线圈组成。首先,确定了线圈的支撑结构及尺寸,并通过计算单匝接收线圈的效率及磁场的不均匀性来确定鞍形以及亥姆霍兹线圈的最优尺寸。然后,实测了线圈交流电阻,来评估线圈不同匝数的SNR,发现匝数增多会使得交流电阻显著增加,从而使SNR随着线圈匝数增加先增加后减少。最后,得到了两线圈的最佳匝数,并制作了正交接收线圈,从CuSO_(4)·5H_(2)O体膜以及体内膝关节成像来评估正交接收线圈的性能。在体膜和体内膝关节成像中,正交接收线圈与单通道线圈相比,图像SNR分别最大程度地提升了约33.5%和30.9%。

关键词：磁共振成像超低场膝关节成像正交接收线圈

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Effects of taurine on Bcl-2 and Bax proteins expression in the ischemic myocardium of the rats

Effects of taurine on Bcl-2 and Bax proteins expression in t...

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华东六省一市生物化学与分子生物学会2003年学术交流会

作者： wan Fu-sheng, wang Qing-Song, GONG when-Hua, LUO Da-Ya, ZHAO Xiao-Man, LI Hua (Department of Biochemistry and Molecular Biology,Jiangxi Medical College, Nanchang, 330006, China)

Objective: To investigate the alteration of bcl-2 and bax genes expression in the ischemic myocaradium andthe influence of taurine. Methods: Myocardial ischemia model of rats was induced by ligation of the anterior branchof the left coronary for 4h. All animals were divided into three groups: Sham-operation group. Occlusion group andtaurine group (200mg·kg). The level of myocardial mitochondria Malondialdenyde(MDA)、Superoxide dis-mutase (SOD) and Ca-ATPase activities were determined. The myocardial expression of Bcl-2 and Bax proteinswas detected by immunohistochemistry. Results: Coronary Occlusion of the rats led to significant MDA Content in-

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Security analysis of satellite-to-ground reference-frame-independent quantum key distribution with beam wandering

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Chinese Physics B 2024年第8期33卷 192-201页

作者：周淳赵燕美杨晓亮陆宜飞周雨姜晓磊汪海涛汪洋李家骥江木生汪翔张海龙李宏伟鲍皖苏 Henan Key Laboratory of Quantum Information and Cryptography SSF IEUZhengzhou 450001China Synergetic Innovation Centre of Quantum Information and Quantum Physics University of Science and Technology of ChinaHefei 230026China

The reference-frame-independent(RFI)quantum key distribution(QKD)is suitable for satellite-based links by removing the active alignment on the reference ***,how the beam wandering influences the performance of RFI-QKD remains a pending issue in satellite-to-ground *** this paper,based on the mathematical model for characterizing beam wandering,we present the security analysis for satellite-to-ground RFI-QKD and analytically derive formulas for calculating the secret key rate with beam *** simulation results show that the performance of RFI-QKD is better than the Bennett–Brassard 1984(BB84)QKD with beam wandering in asymptotic ***,the degree of influences of beam wandering is specifically presented for satellite-to-ground RFI-QKD when statistical fluctuations are taken into *** work can provide theoretical support for the realization of RFI-QKD using satellite-to-ground links and have implications for the construction of large-scale satellite-based quantum networks.

关键词： quantum key distribution satellite-to-ground beam wandering

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