检索结果-南通市图书馆

Optical coherence tomography-guided percutaneous transluminal angioplasty in renal artery fibromuscular dysplasia

在线全文

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2020年第3期17卷 173-174页

作者： wai Kin Chi Tan Guang Ming Bryan P yan Division of Cardiology Department of Medicine and TherapeuticsPrince of Wales Hospitalthe Chinese University of Hong KongHong KongChina

A 40-year-old woman was referred for resistant hypertension despite three anti-hypertensive medications including a diuretic at maximum tolerated *** has no family history of fibromuscular dysplasia(FMD).Contrast-enha... 详细信息

关键词： Fibromuscular dysplasia Optical coherence tomography Renal artery stenosis

Shen-Jing as a Chinese Medicine Concept Might Be a Counterpart of Stem Cells in Regenerative Medicine

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2019年第1期25卷 64-70页

作者： REN yan-bo HUANG Jian-hua CAI wai-jiao SHEN Zi-yin Institute of Integrated Chinese and Western Medicine Huashan Hospital Fudan University

As the epitome of the modern regenerative medicine, stem cells were proposed in the basic sense no more than 200 years ago. However, the concept of "stem cells" existed long before the modern medical description. The hypothesis that all things, including our sentient body, were generated from a small origin was shared between Western and Chinese people. The ancient Chinese philosophers considered Jing(also known as essence) as the origin of life. In Chinese medicine(CM), Jing is mainly stored in Kidney(Shen) and the so-called Shen-Jing(Kidney essence). Here, we propose that Shen-Jing is the CM term used to express the meaning of "origin and regeneration". This theoretical discovery has at least two applications. First, the actions underlying causing Shen-Jing deficiency, such as excess sexual intercourse, chronic diseases, and aging, might damage the function of stem cells. Second, a large number of Chinese herbs with Shen-Jing-nourishing efficacy had been proven to affect stem cell proliferation and differentiation. Therefore, if Shen-Jing in CM is equivalent with stem cells in regenerative medicine, higher effective modulators for regulating stem-cell behaviors from Kidney-tonifying herbs would be expected.

关键词： Shen-Jing Kidney essence Kidney tonifying herbs regenerative medicine stem cells

Cancers of the lung, head and neck on the rise: perspectives on the genotoxicity of air pollution

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Cancer 2014年第10期33卷 476-480页

作者： Ian Chi Kei Wong Yuen-Keng Ng Vivian wai yan Lui Pharmacogenomics and Precision Therapeutics Laboratory Department of Pharmacology and PharmacyLi Ka Shing Faculty of MedicineThe University of Hong Kong

Outdoor air pollution has been recently classified as a class I human carcinogen by the World Health Organization(WHO). Cumulative evidence from across the globe shows that polluted air is associated with increased risk of lung, head and neck, and nasopharyngeal cancers—all of which affect the upper aerodigestive tract. Importantly, these cancers have been previously linked to smoking. In this article, we review epidemiologic and experimental evidence of the genotoxic and mutagenic effects of air pollution on DNA, purportedly a key mechanism for cancer development. The alarming increase in cancers of the upper aerodigestive tract in Asia suggests a need to focus government efforts and research on reducing air pollution, promoting clean energy, and investigating the carcinogenic effects of air pollution on humans.

关键词：空气污染头颈部癌症遗传毒性肺癌世界卫生组织上升实验证据

中医古籍急救知识本体构建及可视化研究——以“虫兽咬伤病救治”领域为例

在线全文

学校读者我要写书评

暂无评论

中国中医药图书情报杂志 2024年第4期48卷 87-94页

作者：张仕娜晏峻峰湖南中医药大学湖南长沙410208

目的深度挖掘中医古籍急救知识并进行知识可视化,促进中医古籍急救知识的信息增值和资源积累。方法抽取中医古籍急救知识,利用本体方法和protégé本体工具,实现中医古籍数据资源间的关联组织和可视化。首先,以《肘后备急方》《外台... 详细信息

目的深度挖掘中医古籍急救知识并进行知识可视化,促进中医古籍急救知识的信息增值和资源积累。方法抽取中医古籍急救知识,利用本体方法和protégé本体工具,实现中医古籍数据资源间的关联组织和可视化。首先,以《肘后备急方》《外台秘要》为例,展现中医古籍急救知识关联方法;其次,构建“虫兽咬伤病救治”本体,实例化展示中医古籍急救知识的统一组织和管理;最后,创建中医古籍急救知识的关联,可视化呈现以疾病、古籍、急救原文为对象的语义网络。结果实现中医古籍急救知识的系统化组织和高效管理,且能对知识进行快速获取和精确定位,以“虫兽咬伤病救治”为例实现中医古籍急救知识的语义检索及可视化。结论中医古籍急救知识可通过核心数据元实现关联,通过本体技术可实现多源异构中医古籍知识重组和深度利用,为古代急救知识传承和普及提供路径。

关键词：中医古籍急救知识本体构建数据关联可视化

机械辅助循环在心肌梗死后室间隔穿孔治疗中的临床应用进展

在线全文

学校读者我要写书评

暂无评论

中国心血管病研究 2024年第7期22卷 658-664页

作者：王炳然张岩中国医学科学院北京协和医学院国家心血管病中心阜外医院心脏外科北京市100037

心肌梗死后室间隔穿孔(post-infarct ventricular septal rupture,PIVSR)是心肌梗死的严重并发症,常表现为心源性休克,即使提供及时干预,患者院内病死率仍极高。目前指南建议对所有患者立即进行手术,但理想的干预时机仍存在争议。近年来... 详细信息

心肌梗死后室间隔穿孔(post-infarct ventricular septal rupture,PIVSR)是心肌梗死的严重并发症,常表现为心源性休克,即使提供及时干预,患者院内病死率仍极高。目前指南建议对所有患者立即进行手术,但理想的干预时机仍存在争议。近年来,包括IABP、体外膜肺氧合(extracorporeal membrane oxygenation,ECMO)、Impella和TandemHeart等在内的现代机械循环支持(mechanical circulatory support,MCS)技术发展迅速,为患者提供稳定血流动力学支持的同时使延迟手术治疗成为可能,其可能成为PIVSR患者成功救治的新希望。然而,相关临床证据的缺乏一定程度上限制了MCS的进一步推广,不同MCS策略的比较和选择也成为PIVSR患者救治过程中丞待解决的关键性问题,基于这些疑问本文就PIVSR患者中MCS的辅助治疗作一综述。

关键词：急性心肌梗死心肌梗死后室间隔穿孔机械循环支持体外膜肺氧合

A Cardiomyopeptin Preparation Protects against Isoproterenol-Induced Chronic Heart Failure in Rats

在线全文

学校读者我要写书评

暂无评论

Chinese Medicine 2023年第4期14卷 242-254页

作者： Zumeng Xia Hoi yan Leung Hoi Ling Siu Chung wai Chan Kam Ming Ko R&D Center Infinitus China Limited Guangzhou China Division of Life Science Hong Kong University of Science & Technology Hong Kong China

The present study investigated the effect of an herbal extract-supplemented cardiomyopeptin preparation (HECP), in the rat model of chronic heart failure. HECP pre-/co-treatment at a daily dose of 0.072 to 0.124 g/kg for 30 days protected against isoproterenol (ISO)-induced chronic myocardial damage in rats in a dose-dependent manner, with the extent of protection, as assessed by plasma cardiac troponin I level, being up to 76%. The cardioprotection afforded by HECP was associated with the enhancement of myocardial mitochondrial antioxidant status, amelioration of plasma parameters on cardiac dysfunction and hypertrophy, as well as an increase in myocardial endothelial nitric oxide synthase activity. Myocardial apoptotic and anti-apoptotic parameters were suppressed and stimulated, respectively. The cardioprotection afforded by HECP was accompanied by an increase in exercise capacity, an indirect functional index of the myocardium, in ISO-challenged rats. In conclusion, HECP may offer a promising prospect in preventing chronic heart failure in human subjects.

关键词： Cardiomyopeptin Herbal Extract Chronic Heart Failure Isoproterenol

FOTool: Modelling Indigenous Community Cultures in Sarawak

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Software Engineering and Applications 2014年第8期7卷 720-729页

作者： Edwin Mit Ng Bong Ding cheah wai Shiang Faculty of Computer Science and Information Technology Universiti Malaysia Sarawak Kota Samarahan Malaysia

Formal-Object Tool (FOTool) is a software modelling approach that integrates formal specification and object oriented model. FOTool integrates the rigour of formal methods and the ease of use of OO techniques. The idea of FOTool is to provide an easy interface by allowing the application developer to develop the software model by using the object-models, while the verification of the models is carried out by using formal models. Before the verification process, the object static and dynamic models need to be transformed into formal models based on the transformation rules defined in FOTool. This paper presents the FOTool architecture, the transformation rules from object to formal models, and discusses the application of FOTool in our continuous research in modeling, the indigenous communities’ knowledge in Sarawak, and also the challenges of modelling the complex cultural, taboos and beliefs of indigenous communities. The knowledge is generated from the heterogeneous cultural, taboos and beliefs of various ethnic groups in Sarawak. The traditional knowledge is then mapped to a logical explanation in relation to modern life style.

关键词： Software Modelling Formal Method Object Model Model Integration

A monolithic InP/SOI platform for integrated photonics

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Light(Science & Applications) 2021年第11期10卷 2143-2152页

作者： Zhao yan Yu Han Liying Lin Ying Xue Chao Ma wai Kit Ng Kam Sing Wong Kei May Lau Department of Electronic and Computer Engineering Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina Department of Physics and William Mong Institute of Nano Science and Technology Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina

The deployment of photonic integrated circuits(PICs)necessitates an integration platform that is scalable,high-throughput,cost-effective,and *** we present a monolithic InP on SOI platform to synergize the advantages of two mainstream photonic integration platforms:Si photonics and InP *** monolithic InP/SOI platform is realized through the selective growth of both InP sub-micron wires and large dimension InP membranes on industry-standard(001)-oriented silicon-on-insulator(SOI)*** epitaxial InP is in-plane,dislocation-free,site-controlled,intimately positioned with the Si device layer,and placed right on top of the buried oxide layer to form“InP-on-insulator”.These attributes allow for the realization of various photonic functionalities using the epitaxial InP,with efficient light interfacing between the III-V devices and the Si-based *** exemplify the potential of this InP/SOI platform for integrated photonics through the demonstration of lasers with different cavity designs including subwavelength wires,square cavities,and *** results here mark a critical step forward towards fully-integrated Si-based PICs.

关键词： SOI monolithic integration

Efficacy of vasopressin, steroid, and epinephrine protocol for in-hospital cardiac arrest resuscitation: a systematic review and meta-analysis of randomized controlled trials with trial sequential analysis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2022年第9期19卷 705-711页

作者： Danish Iltaf Satti yan Hiu Athena Lee Keith Sai Kit Leung Jeremy Man Ho Hui Thompson Ka Ming Kot Arslan Babar Gauranga Mahalwar Abraham KC wai Tong Liu Leonardo Roever Gary Tse Jeffrey Shi Kai Chan International Health Informatics Study(IHIS)Network Cardiovascular Analytics Group Hong KongChina-UK Collaboration Emergency Medicine Unit Li Ka Shing Fac-ulty of MedicineThe University of Hong KongHong KongChina Aston Medical School Faculty of Health&Life SciencesAston UniversityBirminghamUnited Kingdom Li Ka Shing Faculty of Medicine The University of Hong KongHong KongChina Department of Anaesthesia and Pain Service Princess Margaret HospitalLai Chi KokKowloonHong KongChina Department of Medicine Cleveland Clinic FoundationClevelandUSA Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease Department of CardiologyTianjin Institute of Cardi-ologySecond Hospital of Tianjin Medical UniversityTianjinChina Department of Clinical Research Federal Uni-versity of UberlândiaUberlândiaBrazil Kent and Medway Medical School CanterburyKentUnited Kingdom 不详

OBJECTIVES To assess the effect of vasopressin,steroid and epinephrine(VSE)combination therapy on return of spontan-eous circulation(ROSC)after in-hospital cardiac arrest(IHCA),and test the conclusiveness of evidence using trial sequential ana-lysis(TSA).METHODS The systematic search included PubMed,EMBASE,Scopus,and Cochrane Central Register of Controlled *** controlled trials(RCTs)that included adult patients with IHCA,with at least one group receiving combined VSE therapy were *** was extracted independently by two *** main outcome of interest was *** out-comes included survival to hospital discharge or survival to 30 and 90 days,with good neurological *** We included a total of three RCTs(n=869).Results showed that VSE combination therapy increased ROSC(risk ra-tio=1.41;95%CI:1.25-1.59)as compared to *** demonstrated that the existing evidence is *** was also validated by the alpha-spending adjusted relative risk(1.32[1.16,1.49],P<0.0001).Other outcomes could not be meta-analysed due to differences in timeframe in the included *** VSE combination therapy administered in cardiopulmonary resuscitation led to improved rates of ***-ture trials of VSE therapy should evaluate survival to hospital discharge,neurological function and long-term survival.

关键词： resuscitation analysis return