检索结果-南通市图书馆

Salivary C-reactive protein and mean platelet volume as possible diagnostic markers for late-onset neonatal pneumonia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Pediatrics 2024年第1期13卷 41-51页

作者： wafaa Ahmed Metwali Abdelrahman mohamed Elmashad Sahar Mohey Eldin Hazzaa Mohammed Al-Beltagi mohamed Basiony Hamza Department of Pediatric Faculty of MedicineTanta UniversityTanta 31511AlgahrbiaEgypt Department of Clinical Pathology Faculty of MedicineTanta UniversityTanta 31511AlgahrbiaEgypt Department of Pediatric University Medical CenterDr.Suliaman Al Habib Medical GroupManama 26671ManamaBahrain Department of Pediatric University Medical CenterKing Abdulla Medical CityArabian Gulf UniversityManama 26671ManamaBahrain

BACKGROUND Neonatal sepsis,a formidable threat to newborns,is a leading cause of neonatal mortality,with late-onset sepsis manifesting after 72 hours post-birth being particularly ***,a prevalent sepsis presentation,poses a significant risk,especially during the neonatal phase when lung defenses are *** diagnosis of pneumonia is imperative for timely and effective ***,a minimally invasive diagnostic medium,holds great promise for evaluating infections,especially in *** To investigate the potential of serum C-reactive protein(CRP),salivary CRP(sCRP),and mean platelet volume(MPV)as diagnostic markers for late-onset neonatal pneumonia(LONP).METHODS Eighty full-term neonates were systematically examined,considering anthropometric measurements,clinical manifestations,radiology findings,and essential biomarkers,including serum CRP,sCRP,and *** The study reveals noteworthy distinctions in serum CRP levels,MPV,and the serum CRP/MPV ratio between neonates with LONP and healthy *** exhibited a robust discriminatory ability[area under the curve(AUC)=0.87]with high sensitivity and specificity at a cutoff value of>*** between serum CRP,sCRP,and MPV were also ***,sCRP demonstrated excellent predictive value for serum CRP levels(AUC=0.89),underscoring its potential as a diagnostic *** This study underscores the diagnostic promise of salivary and serum biomarkers,specifically MPV and CRP,in identifying and predicting LONP among *** findings advocate for further research to validate their clinical utility in larger neonatal cohorts.

关键词： Neonatal sepsis Late-onset pneumonia Salivary C-reactive protein Mean platelet volume Diagnostic markers Newborn infections

Preliminary Palynostratigraphic Data on the Middle Albian-Lower Cenomanian of the Tarfaya Basin, Southwest Morocco

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Geology 2024年第4期14卷 548-568页

作者： Khaoula Chafai Touria Hssaida wafaa Maatouf mohamed Z. Yousfi Sara Chakir Soukaina Jaydawi Hanane Khaffou Department of Geology Faculty of Sciences Ben M&#8217Sik University Hassan II Casablanca Morocco Department of Petroleum Laboratory Office National des Hydrocarbures et des Mines Rabat Morocco Department of Geology Faculty of Sciences Dhar El Mahraz Sidi Mohamed Ben Abdellah University Fes Morocco Department of Geology Faculty of Sciences Mohammed V University Rabat Morocco

The Tarfaya-Laayoune-Boujdour basin is of great interest to oil exploration;on this aspect, there has been exploration by the Moroccan National Office of Hydrocarbons and Mining, which has shown indices of oil and/or gas recorded in most wells drilled in the Moroccan Atlantic margin. FD-1 well, object of this study, is one of these wells located in the offshore Tarfaya-Laayoune-Boujdour basin. A palynological examination of the processed samples revealed the existence of organic palynomorphs, well conserved and rich in dinoflagellate cysts. The latter are composed of worldwide marker taxa of high stratigraphic resolutions. Thus, the middle upper Albian (3408 - 3408.5 m) is determined by the presence of Cribroperidinium tensiftense, Tehamadinium coummia, Spiniferella cornuta, Chichaouadinium vestitum, Dinopterygium alatum and Litosphaeridium arundum. The upper Albian (3406.5 - 3408 m) is characterized by the FOs of marker taxa: Cyclonephelium chabaca, Cribroperidinium auctificum and Chichaouadinium vestitum. Lastly, the upper Albian-lower Cenomanian transition is defined between 3404 m and 3406.50 m, as suggested by the FOs of Chichaouadinium boydii, Dinopterygium tuberculatum, Sepispinula ancorifera, Litosphaeridium conispinum, Prolixosphaeridium conulum and Xenascus ceratioides.

关键词： Morocco Tarfaya-Laayoune-Boujdour Basin Albian-Cenomanian Transition Dinoflagellate Cysts Palynostratigraphy

MTP genetic variants associated with non-alcoholic fatty liver in metabolic syndrome patients

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genes & Diseases 2017年第4期4卷 222-228页

作者： Weaam Gouda Esmat Ashour Yehia Shaker wafaa ezzat Biochemistry Dept. National Research CenterDokkiGizaEgypt Internal Medicine Dept. National Research CenterDokkiGizaEgypt

This study was performed for investigation the relationship between variants of MTP gene polymorphism and the development of NAFLD in patients with and without *** study was included 174 NAFLD patients(106 with MS and 68 without MS),and 141 healthy control *** 493 G/T polymorphism of MTP gene was evaluated by PCR-RFLP *** frequency of MTP TT genotype and T allele were significantly higher in NAFLD patients when compared to healthy ***,a significant association in MTP gene polymorphism was observed in NAFLD patients with MS compared to NAFLD patients without MS and *** study suggested that MTP 493 G/T gene polymorphism may act as susceptibility biomarker for NAFLD and MS.

关键词： Genetic variants Metabolic syndrome(MS) Microsomal triglyceride transfer protein(MTP) Non-alcoholic fatty liver disease(NAFLD) PCR-RFLP

A new systematic firefly algorithm for forecasting the durability of reinforced recycled aggregate concrete

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Structural and Civil Engineering 2022年第3期16卷 329-346页

作者： wafaa mohamed SHABAN Khalid ELBAZ mohamed AMIN Ayat gamal ASHOUR Department of Civil and Environmental Engineering College of EngineeringShantou UniversityShantou 515063China Department of Civil Engineering Misr Higher Institute of Engineering and TechnologyMansouraEgypt Department of Civil Engineering Higher Future Institute of Engineering and TechnologyMansouraEgypt Guangdong Engineering Center for Structure Safety and Health Monitoring Shantou UniversityShantou 515063China Civil and Architectural Construction Department Faculty of Technology and EducationSuez UniversityIsmailiaEgypt Department of Civil and Environmental Engineering Collage of EngineeringUniversity of SharjahSharjah 27272UAE

This study presents a new systematic algorithm to optimize the durability of reinforced recycled aggregate *** proposed algorithm integrates machine learning with a new version of the firefly algorithm called chaotic based firefly algorithm(CFA)to evolve a rational and efficient predictive *** CFA optimizer is augmented with chaotic maps and Levy flight to improve the firefly performance in forecasting the chloride penetrability of strengthened recycled aggregate concrete(RAC).A comprehensive and credible database of distinctive chloride migration coefficient results is used to establish the developed algorithm.A dataset composite of nine effective parameters,including concrete components and fundamental characteristics of recycled aggregate(RA),is used as input to predict the migration coefficient of strengthened RAC as output,k-fold cross validation algorithm is utilized to validate the hybrid *** numerical benchmark analyses are applied to prove the superiority and applicability of the CFA algorithm in predicting chloride *** show that the developed CFA approach significantly outperforms the firefly algorithm on almost tested functions and demonstrates powerful *** addition,the proposed strategy can be an active tool to recognize the contradictions in the experimental results and can be especially beneficial for assessing the chloride resistance of RAC.

关键词： chloride penetrability recycled aggregate concrete machine learning concrete components durability

Immobilization of Co(Ⅱ) Ions in Cement Pastes and Their Effects on the Hydration Characteristics

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2011年第1期27卷 74-80页

作者： Eisa Hekal Essam Kishar wafaa Hegazi Maha mohamed Chemistry Department Faculty of ScienceAin Shams University Chemistry Department Women s College for ArtsScience and EducationAin Shams University

The immobilization of Co（Ⅱ） in various cement matrices was investigated by using the solidification/stabilization（S/S） *** different cement pastes used in this study were ordinary Portland cement in absence and presence of water reducing-and water repelling-admixtures as well as blended cement with *** ratios of Co（Ⅱ） were used（0.5% and 1.0% by weight of the solid binder）.The hydration characteristics of the used cement pastes were tested via the determination of the combined water content,phase composition and compressive strength at different time intervals up to 180 *** degree of immobilization of the added heavy metal ions was evaluated by determining the leached ion concentration after time intervals extended up to 180 *** leachability experiments were carried out by using two modes：the static and the semi-dynamic leaching *** was noticed that the concentration of the leached Co2＋ ions in the static mode of leachability was lower than the solubility of its hydroxide in all the investigated cement pastes.

关键词： Hydration characteristic of cement Admixtures Immobilization Heavy metals

Insights for hepatitis C virus related hepatocellular carcinoma genetic biomarkers: Early diagnosis and therapeutic intervention

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Hepatology 2016年第30期8卷 1251-1261页

作者： wafaa M ezzat Khalda Sayed Amr Department of Internal Medicine National Research Center Department of Medical Molecular Genetics National Research Center

The current review explores the role of emerging molecular contributing factors in liver carcinogenesis on top of hepatitis C virus(HCV). Here we will try to discuss the role genetic and epigenetic factors in pathogenesis of hepatocellular carcinoma. Understanding the role of these factors will help in discovering the mystery of liver carcinogenesis on top of chronic HCV infection. Moreover, use of the studied molecular factors will provide the hepatologists with tailored diagnostic promising biomarkers and flatten the way for establishment of emerging molecular treatment based on exploring the molecular subscription of this aggressive liver cancer.

关键词： Hepatitis C virus Hepatocellular carcinoma Genetic Epigenetic Diagnosis

Unique situation of hepatocellular carcinoma in Egypt:A review of epidemiology and control measures

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2021年第12期13卷 1919-1938页

作者： Reem ezzat mohamed Eltabbakh mohamed El Kassas Internal Medicine Department Faculty of MedicineAssiut UniversityAssiut 71515Egypt Tropical Medicine Department Faculty of MedicineAin Shams UniversityCairo 11566Egypt Endemic Medicine Department Faculty of MedicineHelwan UniversityCairo 11795CairoEgypt

Hepatocellular carcinoma(HCC)is the sixth most common primary malignancy worldwide,and the third most common cause of death among cancers *** occurs in several pre-existing conditions,including hepatitis C,hepatitis B virus,and non-alcoholic *** used to be the country with the heaviest hepatitis C virus(HCV)*** relationship between HCV and HCC is an important research *** Egypt,HCC is a significant public health problem.A possible cause for the increasing rates of detection of HCC in Egypt is the mass screening program that was carried by the government for detecting and treating HCV.A multidisciplinary approach is now widely applied to HCC management in health centers all over *** treatment modalities are available in Egypt,with success rates comparable to global *** Egyptian health authorities have made the elimination of HCV from Egypt a special priority,and this approach should lead to a decrease in number of HCC cases in the near *** this article we review the current situation of HCC in Egypt,including epidemiological aspects,relevant risk factors for HCC development,strategies,and efforts established by health authorities for the screening and prevention of both HCV and HCC in *** highlight the different modalities for HCC treatment.

关键词： Hepatocellular carcinoma Liver cancer Hepatitis C virus Hepatitis B virus Screening Egypt

Molecular detection of virulence genes in Campylobacter species isolated from livestock production systems in South Africa

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2020年第6期19卷 1656-1670页

作者： Bongekile NGOBESE Oliver Tendayi ZISHIRI mohamed ezzat EL ZOWALATY Discipline of Genetics School of Life SciencesUniversity of KwaZulu-NatalDurban 4000South Africa Zoonosis Science Center Department of Medical Biochemistry and MicrobiologyUppsala UniversityUppsala SE-75185Sweden Infectious Diseases and Anti-Infective Therapy Research Group College of Pharmacy and Sharjah Medical Research InstituteUniversity of SharjahSharjah 27272UAE

Campylobacter species are a major cause of foodborne bacterial infections in both developed and developing countries *** jejuni is responsible for the majority of infectio *** study was con ducted to identify virule nceassociated genes in Campylobacter species isolated from livestock production systems in South Africa.A total of 250 fecal samples consisting of cattle(n=50),chickens(n=50),goats(n=50),sheep(n=50)and pigs(n=50)were randomly collected from livestock in Eastern Cape and KwaZulu-Natal provinces of South Africa between April and October *** samples were an a lyzed for the presence of virule nee genes in Campylobacter species using molecular PCR-based *** was found that 77 and 23%of Campylobacter jejuni and Campylobacter coli respectively were isolated from all the livestock *** were positive significant(P<0.05)correlations amongst all the virulenee genes that were *** and Fisher's exact tests were implemented to test for the effect of livestock species on the presenee or absenee of virule nee gen *** study dem on strated that most of livestock species can pote ntially cause zoonotic infecti on s and food pois oning due to the high prevale nee of *** high prevale nee of virule nee genes highlights the sign ifica nee of Campylobacter\r\livestock production systems in South *** requires the implementation of one-health approaches to reduce the impact of foodborne and zoonotic diseases for the welfare of human and animal health.

关键词： Campylobacter zoonotic cytotoxicity pathogenicity virulenee campylobacteriosis foodbome livestock PCR one-health

Association of vitamin D receptor gene polymorphism(VDR)with vitamin D deficiency,metabolic and inflammatory markers in Egyptian obese women

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Genes & Diseases 2017年第3期4卷 176-182页

作者： Moushira Zaki Sanaa Kamal Walaa ABasha Eman Youness wafaa ezzat Hala El-Bassyouni Khalda Amr Biological Anthropology Department National Research CentreGizaEgypt Medical Biochemistry Department National Research CentreGizaEgypt Internal Medicine Department National Research CentreGizaEgypt Clinical Genetics Department National Research CentreCairoEgypt Medical Molecular Genetics Department National Research CentreEgypt

Vitamin D deficiency might contribute to the pathogenesis of metabolic syndrome and could cause immune *** aim of this study is to analyze the associations between Vitamin D receptor(VDR)gene polymorphism,serum 25-hydroxy vitamin D,metabolic and inflammatory biomarkers in Egyptian obese *** study included 201 obese women with vitamin D deficiency and 249 obese matched age healthy controls with sufficient vitamin D *** age ranged between 25 and 35 *** biomarkers(interleukin-6 and C-reactive protein)and serum 25(OH)D were measured by enzyme-linked immunosorbent *** resistance(IR)was determined by the homeostasis model assessment of insulin resistance(HOMA-IR).Vitamin D receptor(VDR)gene polymorphisms of FokI,ApaI,and TaqI were studied by PCR using the restriction fragment length polymorphism(RFLP)*** women with vitamin D deficiency had significant higher values of inflammatory and metabolic parameters compared to ***-logistic regression showed associations between 25(OH)D deficiency and metabolic components when comparing cases with ***,cases carrying polymorphic alleles showed significant lower levels of serum 25(OH)D and higher HOMA-IR,blood pressure levels and lipid parameters compared to those with the wild type homozygote in obese cases with vitamin D *** D deficiency in Egyptian obese women with vitamin D deficiency is associated with abnormal metabolic components and abnormal inflammatory ***,VDR polymorphisms play important role in immune and inflammation status.

关键词： Inflammatory biomarkers Obese women Vitamin D deficiency Vitamin D receptor(VDR)gene polymorphism Egyptian