检索结果-南通市图书馆

Interaction between diet and genetics in patients with inflammatory bowel disease

World Journal of Gastroenterology 2024年第12期30卷 1644-1650页

作者： Daniéla oliveira Magro Ligia Yukie sassaki Júlio Maria Fonseca Chebli Department of Surgery Faculty of Medical SciencesState University of Campinas(UNICAMP)Campinas 13083-970São PauloBrazil Department of Internal Medicine Medical SchoolSao Paulo State University(UNESP)Botucatu 18618-687São PauloBrazil Department of Medicine University Hospital of the Federal University of Juiz de ForaUniversity of Juiz de Fora School of MedicineJuiz de Fora 36036-247Minas GeraisBrazil

In this editorial,we comment on the article by Marangoni et al,published in the recent issue of the World Journal of Gastroenterology 2023;29:5618-5629,about“Diet as an epigenetic factor in inflammatory bowel disease”.The authors emphasized the role of diet,especially the interaction with genetics,in promoting the inflam-matory process in inflammatory bowel disease(IBD)patients,focusing on DNA methylation,histone modifications,and the influence of *** this editorial,we explore the interaction between genetics,gut microbiota,and diet,in an only ***,we provided dietary recommendations for patients with *** Western diet,characterized by a low fiber content and deficiency the micronutrients,impacts short-chain fatty acids production and may be related to the pathogenesis of *** the other hand,the consumption of the Mediter-ranean diet and dietary fibers are associated with reduced risk of IBD flares,particularly in Crohn’s disease(CD)*** to the dietary guidance from the International Organization for the Study of Inflammatory Bowel Diseases(IOIBD),the regular consumption of fruits and vegetables while reducing the consumption of saturated,trans,dairy fat,additives,processed foods rich in maltodextrins,and artificial sweeteners containing sucralose or saccharine is recommended to CD *** patients with ulcerative colitis,the IOIBD recommends the increased intake of natural sources of omega-3 fatty acids and follows the same restrictive recommendations aimed at CD patients,with the possible inclusion of red *** conclusion,IBD is a complex and hetero-geneous disease,and future studies are needed to elucidate the influence of epigenetics on diet and microbiota in IBD patients.

关键词： Diet Genetics MicroRNAs Gastrointestinal microbiome Inflammatory bowel diseases Crohn’s disease

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

evaluating new biomarkers for diabetic nephropathy:Role ofα2-macroglobulin,podocalyxin,α-L-fucosidase,retinol-binding protein-4,and cystatin C

引用

World Journal of Diabetes 2024年第6期15卷 1212-1225页

作者： Jing-Jing Li Ru-la sa Yu Zhang Zhao-Li Yan Department of Infectious Diseases Inner Mongolia Medical UniversityHohhot First HospitalHohhot 010000Inner Mongolia Autonomous RegionChina Department of endocrinology The Affiliated Hospital of Inner Mongolia Medical UniversityHohhot 010000Inner Mongolia Autonomous RegionChina Department of Dermatology Inner Mongolia Autonomous Region People’s HospitalHohhot 010000Inner Mongolia Autonomous RegionChina

BACKGROUND The intricate relationship between type 2 diabetes mellitus(T2DM)and diabetic nephropathy(DN)presents a challenge in understanding the significance of various biomarkers in *** To elucidate the roles and diagnostic values ofα2-macroglobulin(α2-MG),podocalyxin(PCX),α-L-fucosidase(AFU),retinol-binding protein-4(RBP-4),and cystatin C(CysC)in *** From December 2018 to December 2020,203 T2DM patients were enrolled in the *** these,115 were diagnosed with DN(115 patients),while the remaining 88 patients were classified as *** urinary levels ofα2-MG,PCX,and AFU and the serum concentrations RBP-4 and CysC were measured in conjunction with other relevant clinical indicators to evaluate their potential correlations and diagnostic *** After adjustments for age and gender,significant positive correlations were observed between the biomarkers CysC,RBP-4,α2-MG/urinary creatinine(UCr),PCX/UCr,and AFU/UCr,and clinical indicators such as urinary albumin-to-creatinine ratio(UACR),serum creatinine,urea,24-h total urine protein,and neutrophil-to-lymphocyte ratio(NLR).Conversely,these biomarkers exhibited negative correlations with the estimated glomerular filtration rate(Peceiver operating characteristic(ROC)curve analysis further demonstrated the diagnostic performance of these biomarkers,with UACR showcasing the highest area under the ROC curve(AUC^(ROC))at *** This study underscores the diagnostic significance ofα2-MG,PCX,and AFU in the development of *** biomarkers RBP-4,CysC,PCX,AFU,andα2-MG provide promising diagnostic insights,while UACR is the most potent diagnostic biomarker in assessing DN.

关键词： α2-macroglobulin Podocalysin α-L-fucosidase Retinol binding protein-4 Cystatin C Diabetic nephropathy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Performance of evolutionary optimized machine learning for modeling total organic carbon in core samples of shale gas fields

引用

Petroleum 2024年第1期10卷 150-164页

作者： Leonardo Goliatt C.M.saporetti L.C.oliveira e.Pereira Department of Computational and Applied Mechanics Federal University of Juiz de ForaJuiz de ForaBrazil Department of Computational Modeling Polytechnic InstituteRio de Janeiro State UniversityNova FriburgoBrazil Petrobras Rio de JaneiroBrazil Department of Stratigraphy and Paleontology Rio de Janeiro State UniversityRio de JaneiroBrazil

Rock samples'TOC content is the best indicator of the organic matter in source *** origin rock samples’analysis is used to calculate it manually by *** method requires time and resources because it relies on samples from many well intervals in source ***,research has been done to aid this *** learning algorithms can estimate total organic carbon instead of well logs and stratigraphic *** light of these efforts,the current work present a study on automating the total organic carbon estimation using machine learning approaches improved by an evolutionary methodology to give the model flexibility and *** algorithms,differential evolution,particle swarm optimization,grey wolf optimization,artificial bee colony,and evolution strategies were used to improve machine learning models to predict *** six metaheuristics were integrated into four machine learning methods:extreme learning machine,elastic net linear model,linear support vector regression,and multivariate adaptive regression *** samples from the YuDong-Nan shale gas field,located in the Sichuan basin,were used to evaluate the hybrid *** findings show that combining machine learning models with an evolutionary algorithms in a hybrid fashion produce flexible models that accurately predict *** results show that,independent of the metaheuristic used to guide the model selection,optimized extreme learning machines attained the best performance scores according to six *** hybrid models can be used in exploratory geological research,particularly for unconventional oil and gas resources.

关键词： Total organic carbon Hybrid models Automated machine learning evolutionary algorithms Geology

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

elevation transition of aquatic insects closely matches a thermal feature in the Yungas of Northwestern Argentina

引用

Journal of Mountain Science 2024年第2期21卷 433-448页

作者： Alexandra BUITRAGO-GUACANAMe Carlos MOLINeRI Andrés lira-NORIeGA Daniel Andrés DOS saNTOS Neotropical Biodiversity Institute(CONICeT-UNT) UNT-DomesHorco Molle S/N4107 TucumánArgentina CONACYT Research Fellow Network of Advanced Molecular StudiesInstitute of Ecology A.COld Road to Coatepec 351El HayaCP 91073XalapaVeracruzMexico Biostatistics Chair Faculty of Natural Sciences and IMLNational University of TucumánSan Miguel de TucumánMiguel Lillo 2054000 TucumánArgentina

Temperature is a key factor that shapes the distribution of *** knowledge about how species respond to temperature is relevant to devise strategies for addressing the impacts of climate *** insects are particularly vulnerable to climate change,yet there is still much to learn about their ecology and *** the Yungas ecoregion of Northwestern Argentina,cold-and warm-adapted species of the orders ephemeroptera,Plecoptera,and Trichoptera(ePT)are segregated by *** modeled the ecological niche of South American ePT species in this region using available data and projected their potential distribution in geographic *** were grouped based on their ecogeographic similarity,and we analyzed their replacement pattern along elevation gradients,focusing on the ecotone where opposing thermal preferences *** this interface,we identified critical points where the combined incidence of cold and warm assemblages maximizes,indicating a significant transition *** found that the Montane Cloud Forest holds the interface,with a particularly greater suitability at its lower *** main axis of the interface runs in a N-S direction and falls between 14°C-16°C mean annual *** probability of a particular location within a basin being classified as part of the interface increases as Kira’s warmth index approaches a score around *** the interface is critical for defining the thermal limits of species distribution and designing biomonitoring *** in the location of thermal constants related to mountainous ecotones may cause vertical displacement of aquatic insects and vegetation *** have recognized significant temperature thresholds that serve as indicators of suitability for the *** global warming is anticipated to shift these indicators,we suggest using them to monitor the imprints of climate change on mountain ecosystems.

关键词： Austral Yungas ecological Niche Model ephemeroptera Kira’s warmth index Plecoptera Trichoptera

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The first record of dermochelyid turtles in the eocene of Tierra del Fuego:new insights on the evolution of the Weddellian faunas

引用

Advances in Polar Science 2024年第1期35卷 63-77页

作者： Paula BONA Juliana STeRLI Marcelo saúl de la FUeNTe eduardo OLIVeRO Marta S.FeRNÁNDeZ Marcelo ReGUeRO División Paleontología Vertebrados Museo de La Plata-Anexo IIFacultad de Ciencias Naturales y MuseoUniversidad Nacional de La PlataLa Plata B1900FWAArgentina Consejo Nacional de Investigaciones Científicas y Técnicas(CONICeT) Ciudad Autónoma de Buenos Aires C1425FQBArgentina Museo Paleontológico egidio Feruglio Trelew U9100Argentina Instituto de evolución Ecología Histórica y Ambiente-CONICETSan Rafael CP5600Argentina Centro Austral de Investigaciones Científicas-CONICeT Universidad Nacional de Tierra del FuegoUshuaia CP 9410Argentina División Paleontología Vertebrados Museo de La PlataUniversidad Nacional de La PlataLa Plata B1900FWAArgentina

The Antarctic Paleogene marine fossil record has been the key to reconstructing the evolution of the Weddellian Sea and final dismemberment of Southern *** this context,eocene marine vertebrates from Seymour(Marambio)Island have provided valuable *** present the first eocene record of marine reptiles from the southern Atlantic Coast of South *** corresponds to several postcranial turtle remains represented by a proximal end of the right humerus,three caudal and one thoracic vertebrae,a fragment of the left pubis,and ten ossicles of the dorsal carapace,coming from the Leticia Formation(late-mid eocene)at Cabo Tiburones,Tierra del Fuego,*** materials show severalfeatures such as the size and general morphology of the humerus and vertebrae,and the presence of relatively small,irregular,smooth,and unkeeled ossicles,which allow us to assign them to Dermochelyidae *** are a cosmopolitan group ofcryptodiran turtles,registered from the late Cretaceous up to the recent,with some physiological-biological peculiarities(e.g.,endothermy and an exclusive jellyfish-based diet)and characterized by the presence of an osseous carapace formed by *** new finding from the Leticia Formation is an addition to the scarce and extremely fragmentary record of eocene dermochelyids from the southern seas like those from the la Meseta and Submeseta formations(Antarctica)and the waihao and Burnside formations(New Zealand).This new information allows us to discuss the presence of these turtles in such high latitudes in the past and its implication in the evolution of the Weddellian fauna.

关键词： marine reptiles sea turtles Dermochelyidae Paleogene la Meseta Formation Submeseta Formation Leticia Formation

来源：

维普期刊数据库

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Synergic catalysis of W and Ni originating from substitution of trivacant phosphotungstate for the selective oxidation of aniline to azoxybenzene

引用

Chinese Chemical Letters 2024年第2期35卷 558-563页

作者： Sheng Cai Xiao-Yuan Wu Weiming Wu sa-sa wang Can-Zhong Lu CAS Key laboratory of Design and Assembly of Functional Nanostructures and Fujian Provincial Key Laboratory of NanomaterialsFujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China College of Chemistry and Materials Science Fujian Normal UniversityFuzhou 350117China Xiamen Institute of Rare earth Materials Chinese Academy of SciencesXiamen 361021China University of Chinese Academy of Sciences Beijing 100049China

Partial substitution of polyoxometalate(POM)is an efficient route to modulate the catalytic property of maternal *** this work,a new Keggin type POM involving{Ni 6}cluster,{[Ni(H_(2)O)_(2)(Dach)_(2)][Ni(Dach)_(2)]_(2)}{[Ni_(6)Cl(μ-OH)_(3)(H_(2)O)(Dach)_(3)(WO_(4))(PW9 O_(3)_(4))][Ni_(6)(μ-OH)_(3)(H_(2)O)_(2)(Dach)_(3)(WO_(4))(PW9 O_(3)_(4))]}Cl·27H_(2)O,(1,Dach=1,2-diaminocyclohexane)was *** 1 shows excellent catalytic performance in the selective oxidation of aniline to azoxybenzene(AOB)in *** apparently different results from that with the matrix{PW_(9)O_(34)}({PW9})suggest the successful regulation of the catalytic property of{PW9}by the introduction of the{Ni6}cluster into the *** experimental results indicate that the highlighted performance of 1 is contributed by the synergy of W and Ni sites,which are respectively responsible for the oxidation and condensation steps in the production of *** good selectivity to AOB is essentially attributed to the effective modulation of the reaction rates of oxidation and condensation steps by W and Ni sites,respectively.

关键词： Polyoxometalate {Ni_(6)}cluster Modulated catalytic property Aniline oxidation Azoxybenzene

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Gentiana macrophylla Pall.:a review of the basic source,traditional use,chemical components,pharmacological activities and quality control

引用

Traditional Medicine Research 2024年第12期9卷 13-30页

作者： Qi-er Mu Yi-sa A Yan-Qiu Bai Chu-la sa College of Mongolian Medicine Inner Mongolian Medical UniversityJinshan Economic and Technological Development ZoneTumote Left BannerHohhot 010110China

Gentiana macrophylla Pall.(***),whose genus and family belong to the Gentianaceae and *** main distribution centers of *** resources were the Loess Plateau and the eastern Qinghai-Tibet Plateau in ***,as a traditional medicine,has a long history and was used in different ethnic *** roots were used in traditional Chinese medicine,which had the effect of anti-inflammatory,anti-rheumatism,antiviral,promote blood circulation,eliminate swelling and pain,while its flowers were used in traditional Mongolian medicine,which had the effect of removing“Xieriwusu”(“Xieriwusu”means rheumatism),antiviral,reducing *** previous studies,it could be found that there were more than forty components isolated and identified from *** main chemical components were iridoids,flavonoids,triterpenoids,steroids,phenylpropanoids,and *** terpenoid components represented by gentiopicroside and Loganic acid were the main components of the root of ***,which had anti-inflammatory,antioxidant,hepatoprotective,analgesic,antibacterial and promote gastrointestinal tract *** flower mainly contains isoorientin and isovitexin as the representative of *** have anti-tumor,liver protection,heart protection,inhibition of acetylcholinesterase and inhibition of *** could be seen from previous studies that the research on *** was mainly focused on the root,and the flower was rarely *** was reported that the experimental data of the anti-inflammatory and anti-tumor effects of *** flowers show that its curative effect was very ***,the flowers of the flower of *** can be used as potential medicinal parts for *** that flavonoids are mostly found in flowers and exhibit a range of functions,it is possible to investigate the flowers in order to learn more about ***’s potential medical *** on botanical books,Chi

关键词： Gentiana macrophylla Pall basic source chemical component pharmacological activity quality control

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Stereotactic body radiotherapy in pancreatic adenocarcinoma

引用

Hepatobiliary & Pancreatic Diseases International 2024年第1期23卷 14-19页

作者： Carolina de la Pinta Radiation Oncology Department Ramón y Cajal University HospitalIRYCISAlcaláUniversity28034 MadridSpain

Background:Stereotactic body radiotherapy(SBRT)in pancreatic cancer allows high delivery of radiation doses on tumors without affecting surrounding *** review aimed at the SBRT application in the treatment of pancreatic *** sources:We retrieved articles published in MeDLINe/PubMed from January 2017 to December *** used in the search included:“pancreatic adenocarcinoma”OR“pancreatic cancer”AND“stereotactic ablative radiotherapy(saBR)”OR“stereotactic body radiotherapy(SBRT)”OR“chemoradiotherapy(CRT)”.english language articles with information on technical characteristics,doses and fractionation,indications,recurrence patterns,local control and toxicities of SBRT in pancreatic tumors were *** articles were assessed for validity and relevant ***:Optimal doses and fractionation have not yet been ***,SBRT could be the standard treatment in patients with pancreatic adenocarcinoma in addition to ***,the combination of SBRT with chemotherapy may have additive or synergic effect on pancreatic ***:SBRT is an effective modality for patients with pancreatic cancer,supported by clinical practice guidelines as it has demonstrated good tolerance and good disease *** opens a possibility of improving outcomes for these patients,both in neoadjuvant treatment and with radical intent.

关键词： Chemoradiotherapy Pancreatic adenocarcinoma Radiotherapy Stereotactic body radiotherapy Stereotactic ablative radiotherapy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Bioinspired nanotransducers for neuromodulation

引用

Nano Research 2024年第2期17卷 618-632页

作者： Fan Yang Xiang Wu sa Cai Guosong Hong Department of Materials Science and engineering Stanford UniversityStanfordCA 94305USA Wu Tsai Neurosciences Institute Stanford UniversityStanfordCA 94305USA School of Science Shenzhen Campus of Sun Yat-sen UniversityShenzhen 518107China

The field of neuromodulation has experienced significant advancements in the past decade,owing to breakthroughs in disciplines such as materials science,genetics,bioengineering,photonics,and *** convergence of these fields has resulted in the development of nanotransducers,devices that harness the synergies of these diverse *** nanotransducers,essential for neuromodulation,often draw inspiration from energy conversion processes found in nature for their unique *** this review,we will delve into the latest advancements in wireless neuromodulation facilitated by optical,magnetic,and mechanical *** will examine their working principles,properties,advantages,and limitations in comparison to current methods for deep brain neuromodulation,highlighting the impact of natural systems on their design and ***,we will underscore potential future directions,emphasizing how continued progress in materials science,neuroscience,and bioengineering might expand the horizons of what is achievable with nanotransducer-enabled neuromodulation.

关键词： bioinspired synthesis neuromodulation mechanoluminescence focused ultrasound nanotransducers sono-optogenetics

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Review of Networked Microgrid Protection:Architectures,Challenges,Solutions,and Future Trends

引用

CSee Journal of Power and energy Systems 2024年第2期10卷 448-467页

作者： Jorge de la Cruz Ying Wu John e.Candelo-Becerra Juan C.Vasquez Josep M.Guerrero Center for Research on Microgrids(CROM) Department of Energy TechnologyAalborg University9220 AalborgDenmark Facultad de Minas Departamento de Energia Eléctrica y AutomaticaUniversidad Nacional de ColombiaSede MedellinCarrera 80 No.65-223RobledoMedellin 050041Colombia. Center for Research on Microgrids at UPC(UPC CROM) Department of Electronic EngineeringTechnical University of Catalonia(UPC)08019 Barcelona Spain ICReA Pg.Lluis Companys 2308010 BarcelonaSpain Center for Research on Microgrids at AAU(AAU CROM) AAU EnergyAalborg University(AAU)9220 Aalborg EastDenmark

Design and selection of advanced protection schemes have become essential for reliable and secure operation of networked *** protection schemes that allow correct operation of microgrids have been proposed for individual systems in different topologies and ***,protection schemes for networked microgrids are still in devel-opment,and further research is required to design and operate advanced protection in interconnected *** of these microgrids in different nodes with various intercon-nection technologies increases fault occurrence and complicates protection *** paper aims to point out challenges in developing protection for networked microgrids,potential solutions,and research areas that need to be addressed for their ***,this article presents a systematic analysis of different microgrid clusters proposed since 2016,including several architectures of networked microgrids,operation modes,components,and utilization of renewable sources,which have not been widely explored in previous review ***,the paper presents a discussion on protection systems currently available for microgrid clusters,current challenges,and solutions that have been proposed for these ***,it discusses the trend of protection schemes in networked microgrids and presents some conclusions related to ***—Adaptive eprotection,microgrid cluster,microgrid,multiple microgrid,networked microgrid,real-time simulation,smart grid.

关键词： Adaptive eprotection microgrid cluster microgrid multiple microgrid networked microgrid real-time simulation smart grid

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：