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Chinese Chemical Letters 1999年第11期10卷 899-902页

作者： Hua Yue wu Red Er CHEN Yong Min ZHANG(Department of Cheniistry, Wenzhou Normal College, Wenzhou, 325000)(Departnieni of chemistry. zhejiang university at Xixi Campus, hangzhou, 310028) Department of chemistry Wenzhou Normal College Wenzhou 325000 China Department of chemistry Zhejiang University at Xixi Campus Hangzhou 310028 China

Disulfides were reduced by the Sm/NiCl2 or Sin/NiCI_2 6H_2O system to generate thiolateanion. which reacted further with anhydrides or acyl chlorides to afford thiolesters in good yieldsunder mild and neutral conditions.

关键词： Samarium-nickel (II) chloride. disulfide thiolester.

Functionalized selenium nanoparticles ameliorated acetaminophen-induced hepatotoxicity through synergistically triggering PKCδ/Nrf2 signaling pathway and inhibiting CYP 2E1

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Food Science and Human Wellness 2024年第2期13卷 932-945页

作者： Si Zou Yetao Gong Xiujie Li Yanbin wu Jinzhong wu Jianguo wu Ka-Hing Wong College of Pharmacy Fujian University of Traditional Chinese MedicineFuzhou 350122China Research Institute for Future Food The Hong Kong Polytechnic UniversityHong Kong 999077China Department of Food Science and Nutrition The Hong Kong Polytechnic UniversityHong Kong 999077China

Selenium nanoparticles(SeNPs)have been demonstrated potential for use in diseases associated with oxidative *** SeNPs with lower toxicity and higher biocompatibility could bring better therapeutic activity and clinical application ***,this work was conducted to investigate the protective effect of Pleurotus tuber-regium polysaccharide-protein complex funtionnalized SeNPs(PTR-SeNPs)against acetaminophen(APAP)-induced oxidative injure in HepG2 cells and C57BL/6J mouse *** elucidation of the underlying molecular mechanism,in particular their modulation of Nrf2 signaling pathway was also *** results showed that PTR-SeNPs could significantly ameliorate APAP-induced oxidative injury as evidenced by a range of biochemical analysis,histopathological examination and immunoblotting ***-SeNPs could hosphorylate and activate PKCδ,depress Keap1,and increase nuclear accumulation of Nrf2,resulting in upregulation of GCLC,GCLM,HO-1 and NQO-1 ***,PTR-SeNPs suppressed the biotransformation of APAP to generate intracellular ROS through CYP 2E1 inhibition,restoring the mitochondrial ***,the protective effect of PTR-SeNPs against APAP induced hepatotoxicity was weakened as Nrf2 was depleted in vivo,indicating the pivotal role of Nrf2 signaling pathway in PTR-SeNPs mediated hepatoprotective *** a potential hepatic protectant,PTR-SeNPs could serve as a new source of selenium supplement for health-promoting and biomedical applications.

关键词： PTR-SeNPs(polysaccharide-proteincomplex functionalized selenium nanoparticles) Acetaminophen-induced hepatotoxicity Nuclear factor erythroid 2-related factor 2 Cytochrome P450 enzyme 2E1 Mitochondria

The study on a new technology of waterway information system

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Acta Oceanologica Sinica 2009年第5期28卷 112-127页

作者： HUANG Yu wu Honghai HE Ye YAO Shengchu College of Civil Engineering and Architecture Zhejiang University Hangzhou 310058 China College of Science Zhejiang University Hangzhou 310058 China

It is a lot limitations to survey and design waterway by the CAD technique, due to timely variation of hydrology and ecology in the complicated estuary area, such as Changjing River estuary. In this paper, the advantages of GIS technique is applied to manage and process the multi kind , multi scale and multi time hydrographic parameters, including water depth, current velocity, tidal, waves, wind speed, temperature and salinity etc., also to deal with different projection, different scale charts. Meanwhile, in the paper, combination techniques of GIS and CAD has been developed for unification of the charts for efficient management, two-way automatic carts conversion between GIS and CAD, automatic cutting and assemble of a number of Charts, flight path of the projection of spatial data and coordinate transformation. This new technique has been applied to survey and design waterway of Changing River estuary. The result shows that the combination technology of GIS and CAD has application potentiality in the waterway survey and design.

关键词： GIS CAD waterway information system

A DIRECT METHOD IN OPTIMAL PORTFOLIO AND CONSUMPTION CHOICE

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Applied Mathematics(A Journal of Chinese Universities) 1996年第3期11卷 349-354页

作者： wu ZHEN AND XU WENSHENG (Department of Mathematics,Shandong university, Jinan 250100.)(Department of Applied Mathematics, zhejiang university,hangzhou 310027.)

In this paper we use a direct method to solve the optimal portfolio andconsumption choice problem in the security market for a specific case,in which theutility function is of a given homogenous form, i.e. the so-call... 详细信息

关键词： Optimal strategy portfolio consumption security market.

Spatial Variability of Micronutrients in Rice Grain and Paddy Soil

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Pedosphere 2009年第6期19卷 748-755页

作者： WANG Lin, wu Jia-Ping 2 , LIU Yan-Xuan, HUANG Hui-Qing and FANG Qian-Fang College of Environment and Natural Resources, zhejiang university, hangzhou 310029 (china) College of Environment and Natural Resources Zhejiang University Hangzhou 310029 (China)

Consumption of rice is the main source of micronutrients to human in Asia. A paddy field with unknown anthro- pogenic contamination in Deqing County, zhejiang Province, china was selected to characterize the spatial variability and distribution of micronutrients in rice grain and soil. A total of 96 paired soil and rice grain samples were collected at harvest. The micronutrients in the soil samples were extracted by diethylenetriamine pentaacetic acid （DTPA）. The mean micronutrient concentrations in rice grain were 3.85 μg Cu g^-1, 11.6 μg Fe g^-1, 39.7 μg Mn g^-1 and 26.0 μg Zn g^-1 The mean concentrations were 2.54μg g^-1 for DTPA-Cu, 133.5μg g^-1 for DTPA-Fe, 30.6μg g^-1 for DTPA-Mn, and 0.84μg g^-1 for DTPA-Zn. Semivariograms showed that measured micronutrients in rice grain were moderately dependent, with a range distance of about 110 m. The concentrations of the DTPA-extractable micronutrients all displayed strong spatial dependency, with a range distance of about 60 m. There was some resemblance of spatial structure between soil pH and the grain Cu, Fe, Mn, and Zn. By analogy, similar spatial variation was observed between soil organic matter （SOM） and DTPA-extractable table micronutrients in the soil. Kriging estimated maps of the attributes showed the spatial distributions of the variables in the field, which is beneficial for better understanding the spatial variation of micronutrients and for potentially refining agricultural management practices at a field scale.

关键词： correlation dependency kriging soil properties

Photonic analog signal processing and neuromorphic computing[Invited]

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Chinese Optics Letters 2024年第3期22卷 123-136页

作者： James Garofolo Ben wu Department of Electrical and Computer Engineering Rowan UniversityGlassboroNJ 08028USA

In this review paper,we discuss the properties and applications of photonic computing and analog signal *** computational circuits have large operation bandwidth,low power consumption,and fine frequency control,enabling a wide range of application-specific computational techniques that are impossible to implement using traditional electrical and digital hardware *** advantages are illustrated in the elegant implementation of optical steganography,the real-time blind separation of signals in the same bandwidth,and the efficient acceleration of artificial neural network *** working principles and use of photonic circuits for analog signal processing and neuromorphic computing are reviewed and notable demonstrated applications are highlighted.

关键词： blind-source separation optical steganography neuromorphic photonics

The physiological role of the unfolded protein response in the nervous system

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Neural Regeneration Research 2024年第11期19卷 2411-2420页

作者： Shuangchan wu Wensheng Lin Department of Neuroscience University of MinnesotaMinneapolisMNUSA Institute for Translational Neuroscience University of MinnesotaMinneapolisMNUSA

The unfolded protein response(UPR)is a cellular stress response pathway activated when the endoplasmic reticulum,a crucial organelle for protein folding and modification,encounters an accumulation of unfolded or misfolded *** UPR aims to restore endoplasmic reticulum homeostasis by enhancing protein folding capacity,reducing protein biosynthesis,and promoting protein *** also plays a pivotal role in coordinating signaling cascades to determine cell fate and function in response to endoplasmic reticulum *** research has highlighted the significance of the UPR not only in maintaining endoplasmic reticulum homeostasis but also in influencing various physiological processes in the nervous ***,we provide an overview of recent findings that underscore the UPR’s involvement in preserving the function and viability of neuronal and myelinating cells under physiological conditions,and highlight the critical role of the UPR in brain development,memory storage,retinal cone development,myelination,and maintenance of myelin thickness.

关键词： myelin neuron oligodendrocyte Schwann cell unfolded protein response

The photosynthetic oxygen evolution does not exclude the important role and contribution of bicarbonate photolysis

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Acta Geochimica 2024年第1期43卷 174-179页

作者： Yanyou wu Shaogang Guo State Key Laboratory of Environmental Geochemistry Institute of GeochemistryChinese Academy of SciencesGuiyang 550081People’s Republic of China university of Chinese Academy of Sciences Beijing 100049People’s Republic of China

Photosynthesis is the most important biochemical reaction on Earth. It has co-evolved and developed with the Earth, driving the biogeochemical cycle of all elements on the planet and serving as the only chemical process in nature that can convert light energy into chemical energy. Some heavy oxygen isotopic(^(18)O) labeling experiments have"conclusively" demonstrated that the oxygen released by photosynthesis comes only from water and are written into textbooks. However, it is not difficult to find that bicarbonate has never been excluded from the direct substrate of photosynthesis from beginning to end during the history of photosynthesis research. No convincing mechanism can be used to explain photosynthetic oxygen evolution solely from water photolysis. The bicarbonate effect, the Dole effect, the thermodynamic convenience of bicarbonate photolysis, the crystal structure characteristics of photosystem Ⅱ, and the reinterpretation of heavy oxygen isotopic labeling(^(18)O)experiments all indicate that the photosynthetic oxygen evolution does not exclude the important role and contribution of bicarbonate photolysis. The recently proposed view that bicarbonate photolysis is the premise of water photolysis, bicarbonate photolysis and water photolysis work together with a 1:1(mol/mol) stoichiometric relationship, and the stoichiometric relationship between oxygen and carbon dioxide released during photosynthetic oxygen evolution is also 1:1, has excellent applicability and objectivity, which can logically and reasonably explain the precise coordination between light and dark reactions during photosynthesis, the bicarbonate effect, the Dole effect, the Kok cycle and the neutrality of water and carbon in *** is of great significance for constructing the bionic artificial photosynthetic reactors and scientifically answering the question of the source of elemental stoichiometric relationships in nature.

关键词： Bicarbonate effect Dole effect Kok cycle Heavy oxygen isotope Artificial photosynthetic reactor

A new Metallacrown compound [Ru（Ⅱ）6（SMe）12] formed by reduction of DMSO under mild condition

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A new Metallacrown compound [Ru（Ⅱ）6（SMe）12] formed by r...

Roles of Upper-Level Descending Inflow in Moat Development in Simulated Tropical Cyclones with Secondary Eyewall Formation

中国化学会第五届全国结构化学学术会议

作者： Chuan-De wu~2 Department of chemistry,zhejiang university,hangzhou,310027,P.R.china

＜正＞In the past few years,considerable interests are focused on the construction of metal-organic frameworks（MOFs）for aesthetically appealing nature and potential applications in various research *** the designed ...

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来源： cnki会议评论

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Advances in Atmospheric Sciences 2024年第6期41卷 1100-1114页

作者： Nannan QIN Liguang wu Nanjing Joint Institute for Atmospheric Sciences Nanjing 210041China Shanghai Typhoon Institute China Meteorological AdministrationShanghai 200030China Department of Atmospheric and Oceanic Sciences and Institute of Atmospheric Sciences Fudan UniversityShanghai 200438China Innovation Center of Ocean and Atmosphere System Zhuhai Fudan Innovation Research InstituteZhuhai 518057China

This study investigated the effects of upper-level descending inflow(ULDI)associated with inner-eyewall convection on the formation of the moat in tropical cyclones(TCs)with secondary eyewall formation(SEF).In our numerical experiments,a clear moat with SEF occurred in TCs with a significant ULDI,while no SEF occurred in TCs without a significant *** eyewall convection developed more vigorously in the control run.A ULDI occurred outside the inner-eyewall convection,where it was symmetrically *** ULDI was initially triggered by the diabatic warming released by the inner eyewall and later enhanced by the cooling below the anvil *** ULDI penetrated the outer edge of the inner eyewall with relatively dry air and prevented excessive solid-phase hydrometeors from being advected further *** produced extensive sublimation cooling of falling hydrometeors between the eyewall and the outer *** sublimation cooling resulted in negative buoyancy and further induced strong subsidence between the eyewall and the outer *** a result,a clear moat was *** of the moat in the ongoing SEF prevented the outer rainband from moving farther inward,helping the outer rainband to symmetrize into an outer *** the sensitivity experiment,no significant ULDI formed since the eyewall convection was weaker,and the eyewall anvil developed relatively lower,meaning the formation of a moat and thus an outer eyewall was less *** study suggests that a better-represented simulation of inner-eyewall convective structures and distribution of the solid-phase hydrometeors is important to the prediction of SEF.

关键词： tropical cyclone secondary eyewall formation upper-level descending inflow eyewall convection