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关节镜下跖筋膜松解联合跟骨骨刺清除术治疗顽固性跟痛症

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实用骨科杂志 2024年第2期30卷 133-137页

作者：邓斌郑臣校吴健波张绍海林小永广州中医药大学附属中山中医院广东中山528400

目的探讨关节镜下跖筋膜松解联合跟骨骨刺清除术治疗顽固性跟痛症的临床疗效。方法回顾性分析中山市中医院创伤骨科足踝组2018年4月至2022年6月期间,关节镜下采用跖筋膜松解联合跟骨骨刺清除术治疗顽固性跟痛症的患者30例,其中男8例,女2... 详细信息

目的探讨关节镜下跖筋膜松解联合跟骨骨刺清除术治疗顽固性跟痛症的临床疗效。方法回顾性分析中山市中医院创伤骨科足踝组2018年4月至2022年6月期间,关节镜下采用跖筋膜松解联合跟骨骨刺清除术治疗顽固性跟痛症的患者30例,其中男8例,女22例;年龄43~69岁,平均(54.7±7.9)岁,定期于门诊复诊并完成随访。观察并记录术后相关并发症发生情况并定期复查术侧跟骨侧位X线片判断术侧跟骨骨刺是否复发。通过对比术前、术后1个月、术后3个月及末次随访时患者疼痛视觉模拟评分(visual analogue scale,VAS)、美国足踝外科协会踝-后足(American orthopedic foot and ankle society ankle and hindfoot,AOFAS-AH)评分和跟痛症评分(calcaneodynia score,CS)来评价手术疗效。结论30例患者术后随访时间为12~20个月,平均(16.27±2.32)个月。30例患者术后各观察时间点的VAS评分均低于术前,而AOFAS-AH评分和CS评分均高于术前,手术前后对比差异均有统计学意义(P<0.001)。术后定期复查术侧跟骨侧位X线片示跟骨骨刺均无复发。无一例患者出现血管、神经损伤、术口感染等并发症。结论关节镜下跖筋膜松解联合跟骨骨刺清除术能够显著缓解顽固性跟痛症患者足跟局部疼痛,改善足踝功能,其疗效满意,是一种值得推广的治疗方式。

关键词：顽固性跟痛症跖筋膜跟骨骨刺关节镜

LILRB4, an immune checkpoint on myeloid cells

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Blood Science 2022年第2期4卷 49-56页

作者： Ting Yang Yixin Qian Xiaoting Liang jianbo wu Ming Zou Mi Deng Peking University International Cancer Institute Health Science CenterPeking UniversityBeijingChina Peking University Cancer Hospital and Institute Peking UniversityBeijingChina

Leukocyte immunoglobulin-like receptor B4(LILRB4)is an inhibitory receptor in the LILR family mainly expressed on normal and malignant human cells of myeloid *** binding to ligands,LILRB4 is activated and subsequently recruits adaptors to cytoplasmic immunoreceptor tyrosine inhibitory motifs to initiate different signaling cascades,thus playing an important role in physiological and pathological conditions,including autoimmune diseases,microbial infections,and *** normal myeloid cells,LILRB4 regulates intrinsic cell activation and *** disease-associated or malignant myeloid cells,LILRB4 is significantly correlated with disease severity or patient survival and suppresses T cells,thereby participating in the pathogenesis of various *** summary,LILRB4 functions as an immune checkpoint on myeloid cells and may be a promising therapeutic target for various human immune diseases,especially for cancer immunotherapy.

关键词： Autoimmune disease Cancer Immune checkpoint Immunotherapy Inhibitory receptor LILR LILRB4,MDSC Myeloid cell TAM

糖尿病对关节镜下肩袖修复术后病人肩关节功能恢复影响的临床研究

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骨科 2024年第1期15卷 24-29页

作者：王东李朋赵峰吴剑波邱关羿张宇明山西医科大学第五临床医学院骨科太原030012

目的探讨糖尿病对关节镜下肩袖修复术后病人肩关节功能恢复的影响。方法回顾性分析我科自2019年5月至2022年5月接受关节镜下肩袖修复术的62例肩袖损伤病人的临床资料和随访结果,其中糖尿病组30例,男18例,女12例,年龄为(62.10±11.87)岁... 详细信息

目的探讨糖尿病对关节镜下肩袖修复术后病人肩关节功能恢复的影响。方法回顾性分析我科自2019年5月至2022年5月接受关节镜下肩袖修复术的62例肩袖损伤病人的临床资料和随访结果,其中糖尿病组30例,男18例,女12例,年龄为(62.10±11.87)岁;对照组32例,男18例,女14例,年龄为(63.78±12.98)岁。手术方式均为关节镜下缝线桥技术缝合肩袖。分别记录两组病人术前1周、术后3个月、6个月和12个月各时间点肩关节最大外展角度值,以及肩关节功能评分,包括疼痛视觉模拟量表(visual analogue scale,VAS)评分、美国肩肘外科协会(American Shoulder Elbow Surgeon,ASES)评分、加州大学洛杉矶分校(University of California at Los Angeles,UCLA)肩关节评分以及Constant⁃Murley评分。据此对手术效果进行评估。结果62例病人均未出现伤口感染、术后僵硬、术后再撕裂等并发症。两组病人的肩关节最大外展角度值、VAS评分、ASES评分、UCLA评分以及Constant⁃Murley评分均在术后3个月、6个月和1年得到显著改善(P0.05)。结论糖尿病对关节镜下肩袖修复术后的病人短期恢复会存在影响,但长期临床结果没有显著差异。围手术期血糖控制良好的糖尿病病人在关节镜下肩袖修复术后表现出与非糖尿病病人相当的临床和结构恢复。

关键词：糖尿病肩袖损伤肩关节关节镜修复外科手术

微针注射胶原蛋白及氨甲环酸治疗黄褐斑的临床疗效观察

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中国美容医学 2024年第5期33卷 86-89页

作者：洪圣蓉吴剑波谢君黄竹君张志英武汉大学中南医院皮肤科湖北武汉430062

目的:观察微针注射胶原蛋白及氨甲环酸治疗黄褐斑的临床疗效。方法:选取武汉大学中南医院2023年3月-2023年4月收治的60例黄褐斑患者,采用随机数字表法分为两组。对照组采用微针注射氨甲环酸治疗,观察组给予微针注射胶原蛋白联合氨甲环... 详细信息

目的:观察微针注射胶原蛋白及氨甲环酸治疗黄褐斑的临床疗效。方法:选取武汉大学中南医院2023年3月-2023年4月收治的60例黄褐斑患者,采用随机数字表法分为两组。对照组采用微针注射氨甲环酸治疗,观察组给予微针注射胶原蛋白联合氨甲环酸治疗。统计两组治疗疗效,检测两组面部图像分析参数水平,并评估两组黄褐斑面积和严重指数(Melasma area and severity index,MASI)评分差异。结果:观察组临床总有效治疗率明显高于对照组(P0.05)。治疗后,两组L^(*)值均明显升高(P0.05),治疗后,两组MASI评分均降低(P<0.05),且观察组MASI评分低于对照组(P<0.05)。结论:微针注射胶原蛋白联合氨甲环酸治疗黄褐斑可改善患者色素沉着,提高治疗效果。

关键词：微针注射胶原蛋白氨甲环酸黄褐斑色素沉着

A method to determine the bonded-particle model parameters for simulation of ores

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Particuology 2024年第3期86卷 24-38页

作者： Shuwei wu Guoqiang Wang Longfei Fan Wei Guan jianbo Guo Zhengbin Liu Yukuan Wang School of Mechanical and Aerospace Engineering Jilin UniversityChangchun130025China

The bonded-particle model(BPM)is commonly used in the numerical analysis of ore *** improve the accuracy of simulating the mechanical process of ore process of ore crushing in a crusher,the parameters of the BPM for the ore must be *** this study,a calibration method was proposed for the scientific determination of the parameters of the BPM for ore undergoing uniaxial ***,physical tests and simulations were conducted to determine the mechanical response(uniaxial compressive strength and macroscopic stiffness)of ore during uniaxial ***,the sensitivity of the mechanical response to the values of microscopic parameters was tested using a Plackett-Burman ***,the microscopic parameters with the greatest impact on the response were identified,and the range of parameters that met the target response was determined using a steepest ascent design;Second,a second-order model of the mechanical response was established using the sensitive parameters by combining a Box-Behnken design with response surface methodology to obtain the optimal BPM *** tests showed that the normal stiffness per unit area,critical shear stress,and bonded disk radius had significant effects on the uniaxial compressive strength(UCS)and macroscopic stiffness(MS).To verify the validity of the proposed calibration method,laboratory tests were *** consistency of the simulation results with experimental results indicated that response surface methodology with the Plackett-Burman design,steepest ascent design,and Box-Behnken design can be an effective method for calibrating the BPM of ores.

关键词： Bonded-particle model Discrete element method Calibration method Design of experiment Uniaxial compression test

Clean water generation with switchable dispersion of multifunctional Fe3O4-reduced graphene oxide particles

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Progress in Natural Science:Materials International 2018年第4期28卷 422-429页

作者： Ruijie Zhao Jiale Xu Peng Tao Fenglei Shi Fan Yu Xiaoliang Zeng Chengyi Song jianbo wu Wen Shang Tao Deng State Key Laboratory of Metal Matrix Composites School of Materials Science and Engineering Shanghai Jiao Tong University Guangdong Provincial Key Laboratory of Materials for High Density Electronic Packaging Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences

With the increased need for clean water and decreased supply of fresh water, purification of contaminated water can provide clean water that supplements the fresh water from nature. Physical adsorption, photo-degradation and solar-driven evaporation processes are promising ways to generate clean water with minimum environmental impact. However, different purification process requires different dispersion state of the treating agent to maximize its performance. Herein, we demonstrate that Fe3O4-reduced graphene oxide(MrGO) particles with switchable dispersion can be used as the multifunctional water treating agents to efficiently purify contaminated water through different processes. Under homogenously dispersed nanofluid mode, the MrGO particles have large exposed surface areas and can efficiently remove organic dye pollutants through physical adsorption. The uniform dispersion state also favors high contact efficiency facilitating decontamination of high concentration of organic compounds through solar-driven photocatalytic degradation by the MrGO particles. The excellent magnetic response of MrGO particles not only allows for easy collection of the treating agent from water but also enables assembly of MrGO at the air-water interface with external magnets. Under such interfacial assembled mode, clean water can be distilled out of the contaminated solution with high evaporation efficiency of 74.7% under simulated natural solar radiation. This work demonstrates that dispersion state can be used as another important means to optimize water purification performances.

关键词： Adsorption Photo-degradation Evaporation Dispersion state Water treatment

High?Index?Faceted Ni_3S_2 Branch Arrays as Bifunctional Electrocatalysts for Efficient Water Splitting

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Nano-Micro Letters 2019年第1期11卷 205-216页

作者： Shengjue Deng Kaili Zhang Dong Xie Yan Zhang Yongqi Zhang Yadong Wang jianbo wu Xiuli Wang Hong Jin Fan Xinhui Xia Jiangping Tu State Key Laboratory of Silicon Materials Key Laboratory of Advanced Materials and Applications for Batteries of Zhejiang Province and Department of Materials Science and Engineering Zhejiang University Guangdong Engineering and Technology Research Center for Advanced Nanomaterials School of Environment and Civil Engineering Dongguan University of Technology School of Physical and Mathematical Sciences Nanyang Technological University School of Engineering Nanyang Polytechnic Zhejiang Provincial Key Laboratory for Cutting Tools Taizhou University

For efficient electrolysis of water for hydrogen generation or other valueadded chemicals, it is highly relevant to develop low-temperature synthesis of low-cost and high-e ciency metal sulfide electrocatalysts on a large scale. Herein, we construct a new core–branch array and binder-free electrode by growing Ni_3S_2 nanoflake branches on an atomic-layer-deposited(ALD) TiO_2 skeleton. Through induced growth on the ALD-TiO_2 backbone, cross-linked Ni_3S_2 nanoflake branches with exposed { 210} highindex facets are uniformly anchored to the preformed TiO_2 core forming an integrated electrocatalyst. Such a core–branch array structure possesses large active surface area, uniform porous structure, and rich active sites of the exposed { 210 } high-index facet in the Ni_3S_2 nanoflake. Accordingly, the TiO_2@Ni_3S_2 core/branch arrays exhibit remarkable electrocatalytic activities in an alkaline medium, with lower overpotentials for both oxygen evolution reaction(220 mV at 10 mA cm^(-2)) and hydrogen evolution reaction(112 m V at 10 mA cm^(-2)), which are better than those of other Ni_3S_2 counterparts. Stable overall water splitting based on this bifunctional electrolyzer is also demonstrated.

关键词： Nickel sulfide Core/branch arrays Porous film Bifunctional electrocatalysts Electrochemical water splitting Oxygen evolution reaction(OER) Hydrogen evolution reaction(HER)

Rational construction of cross-linked porous nickel arrays for efficient oxygen evolution reaction

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Chinese Journal of Catalysis 2019年第7期40卷 1063-1069页

作者： Kaili Zhang Shengjue Deng Yu Zhong Yadong Wang jianbo wu Xiuli Wang Xinhui Xia Jiangping Tu State Key Laboratory of Silicon Materials Key Laboratory of Advanced Materials and Applications for Batteries of Zhejiang Provinceand School of MaterialsScience and EngineeringZhejiang UniversityHangzhou 310027ZhejiangChina School of Engineering Nanyang Polytechnic569830Singapore Zhejiang Provincial Key Laboratory for Cutting Tools Taizhou UniversityTaizhou 318000ZhejiangChina

It is important but challenging to design and fabricate an efficient and cost-effective electrocatalyst for the oxygen evolution reaction(OER). Herein, we report free-standing 3 D nickel arrays with a cross-linked porous structure as interesting and high-performance electrocatalysts for OER via a facile one-step electrodeposition method. The 3 D nickel arrays are strongly anchored on the substrate, forming self-supported electrocatalysts with reinforced structural stability and high electrical conductivity. Because of their increased active surface area, abundant channels for electron/ion transportation and enhanced electronic conductivity, the designed 3 D nickel arrays exhibit superior electrocatalytic OER performance with a low overpotential(496 mV at 50 mA cm–2) and a small Tafel slope(43 mV dec–1) as well as long-term stability(no decay after 24 h) in alkaline solution. Our proposed rational design strategy may open up a new way to construct other advanced 3 D porous materials for widespread application in electrocatalysis.

关键词： Oxygen evolution reaction Nickel arrays Electrocatalysis Porous structure Electrodeposition

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东南沿海地区滑坡识别与监测研究进展及趋势

河南水利与南水北调 2024年第7期53卷 92-93页

作者：张士铎王继凯孙强伍剑波邱明杨华北水利水电大学地球科学与工程学院郑州450045 中国地质调查局南京地质调查中心南京210016

中国东南沿海地区地形险峻,地质构造十分复杂,随着东南沿海区域城市化进程的加快以及受极端天气影响严重,滑坡灾害的频发程度不断加剧。滑坡作为一种常见的地质灾害,会给人们的生命财产安全以及当地经济造成严重损失,近年来研究者们加... 详细信息

中国东南沿海地区地形险峻,地质构造十分复杂,随着东南沿海区域城市化进程的加快以及受极端天气影响严重,滑坡灾害的频发程度不断加剧。滑坡作为一种常见的地质灾害,会给人们的生命财产安全以及当地经济造成严重损失,近年来研究者们加强了对滑坡识别和监测的研究。文章通过在滑坡形成因素和失稳机理的基础上,探讨了遥感技术、无人机技术、全球导航卫星系统、高密度电法监测、钻孔监测等多种技术在滑坡识别和监测中的应用,并提出了未来的发展趋势,包括利用人工智能进行滑坡预警、建立一套完整的滑坡监测体系等。对东南沿海地区滑坡识别和监测的研究进展进行阐述,对今后的相关研究具有一定参考价值。

关键词：东南沿海地区滑坡滑坡识别滑坡监测