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智能核电厂的发展及应用

中国核电 2020年第6期13卷 847-850页

作者：黄建华郭天觉中国核动力研究设计院四川成都610000 和昇集团中国香港

很多非核能工业已经广泛利用大数据和机器学习技术提升他们的生产力,而核电厂收集了大量历史、实时运转和维修数据,本论文提出核电厂“数字双胞胎”集成大数据和机器学习技术的构想,这就是数据驱动建模加上物理驱动建模的观念,这将更有... 详细信息

很多非核能工业已经广泛利用大数据和机器学习技术提升他们的生产力,而核电厂收集了大量历史、实时运转和维修数据,本论文提出核电厂“数字双胞胎”集成大数据和机器学习技术的构想,这就是数据驱动建模加上物理驱动建模的观念,这将更有效的利用核电厂历史和实时运转和维修数据,并依此开发预测维护系统和操作辅助工具,建立智能核电厂,目的是帮助核电厂的工程师和操作员更安全、更有效能地运转和维修核电厂。

关键词：智能核电厂核电厂先进仿真器数据同化技术数字双胞胎数据驱动建模物理驱动建模

Adrenomedullin and diabetes

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World Journal of Diabetes 2014年第3期5卷 364-371页

作者： Hoi kin wong Fai Tang Tsang Tommy Cheung Bernard Man Yung Cheung Department of Pharmacology and Pharmacy University of Hong Kong Department of Physiology University of Hong Kong Department of Medicine University of Hong Kong Department of Medicine Queen Mary Hospital

Adrenomedullin(ADM) is a peptide hormone widely expressed in different tissues, especially in the vasculature. Apart from its vasodilatatory and hypotensive effect, it plays multiple roles in the regulation of hormonal secretion, glucose metabolism and inflammatory response. ADM regulates insulin balance and may participate in the development of diabetes. The plasma level of ADM is increased in people with diabetes, while in healthy individuals the plasma ADM concentration remains low. Plasma ADM levels are further increased in patients with diabetic complications. In type 1 diabetes, plasma ADM level is correlated with renal failure and retinopathy, while in type 2 diabetes its level is linked with a wider range of complications. The elevation of ADM level in diabetes may be due to hyperinsulinemia, oxidative stress and endothelial injury. At the same time, a rise in plasma ADM level can trigger the onset of diabetes. Strategies to reduce ADM level should be explored so as to reduce diabetic complications.

关键词： Adrenomedullin Diabetes Diabetic complications Hyperglycemia Therapeutics

Static-Output-Feedback Based Robust Fuzzy Wheelbase Preview Control for Uncertain Active Suspensions With Time Delay and Finite Frequency Constraint

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自动化学报（英文版） 2021年第3期

作者： Wenfeng Li Zhengchao Xie Jing Zhao Pak kin wong Hui Wang Xiaowei Wang

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兒童抽動障礙臨床症狀及腦電圖分析

镜湖医学 2021年第2期21卷 40-41,39页

作者：黃健星黃潔馨宋冬其澳門鏡湖醫院兒科中國

目的探討兒童抽動障礙的臨床症狀特點與腦電圖結果的關係。方法回顧分析自2016年7月~2020年11月到本院兒科門診就診抽動障礙兒童的起病年齡、臨床症狀和腦電圖結果。結果兒童抽動障礙病例共233例,平均起病年齡6.4歲,男女比例為3.7:1,76... 详细信息

目的探討兒童抽動障礙的臨床症狀特點與腦電圖結果的關係。方法回顧分析自2016年7月~2020年11月到本院兒科門診就診抽動障礙兒童的起病年齡、臨床症狀和腦電圖結果。結果兒童抽動障礙病例共233例,平均起病年齡6.4歲,男女比例為3.7:1,76%有不自主眨眼,是最常見的抽動症狀,178例進行腦電圖檢查,腦電圖異常佔7.9%,包括慢波增多2.8%,癇樣放電5.1%。不同性別、年齡、抽動形式的腦電圖慢波異常和癇樣放電發生率差異無統計學意義(P>0.05)。結論兒童抽動障礙的診斷依靠臨床特點,腦電圖是常用的輔助檢查,少數抽動障礙兒童腦電圖可見癇樣放電,利用長程視頻腦電圖明確癇樣放電與不自主動作沒有鎖時關係,可協助排除癲癇性抽搐。

关键词：抽動障礙腦電圖癇樣放電

Review of Feynman’s Path Integral in Quantum Statistics:from the Molecular Schrödinger Equation to Kleinert’s Variational Perturbation Theory

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Communications in Computational Physics 2014年第4期15卷 853-894页

作者： kin-Yiu wong Department of Physics High Performance Cluster Computing CentreInstitute of Computational and Theoretical StudiesHong Kong Baptist University224 Waterloo RoadKowloon TongHong Kong Institute of Research and Continuing Education Hong Kong Baptist University(Shenzhen)

Feynman’s path integral reformulates the quantum Schrödinger differential equation to be an integral *** has been being widely used to compute internuclear quantum-statistical effects on many-body molecular *** this Review,the molecular Schrödinger equation will first be introduced,together with the BornOppenheimer approximation that decouples electronic and internuclear *** effective semiclassical potentials,e.g.,centroid potential,which are all formulated in terms of Feynman’s path integral,will be discussed and *** semiclassical potentials can be used to directly calculate the quantum canonical partition function without individual Schrödinger’s energy *** a result,path integrations are conventionally performed with Monte Carlo and molecular dynamics sampling *** complement these techniques,we will examine how Kleinert’s variational perturbation(KP)theory can provide a complete theoretical foundation for developing non-sampling/non-stochastic methods to systematically calculate centroid *** enable the powerful KP theory to be practical for many-body molecular systems,we have proposed a new path-integral method:automated integrationfree path-integral(AIF-PI)*** to the integration-free and computationally inexpensive characteristics of our AIF-PI method,we have used it to perform ab initio path-integral calculations of kinetic isotope effects on proton-transfer and RNA-related phosphoryl-transfer chemical *** computational procedure of using our AIF-PI method,along with the features of our new centroid path-integral theory at the minimum of the absolute-zero energy(AMAZE),are also highlighted in this review.

关键词： Feynman’s path integral Kleinert’s variational perturbation theory Schrödinger’s equation quantum statistics centroid potential energy quantum tunneling zero-point energy isotope effects

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產後出血性子宮切除的回顧分析

镜湖医学 2014年第2期14卷 40-41,36页

作者：古少君何健菁黃淑健澳門鏡湖醫院婦產科中國

目的探討嚴重產後出血致子宮切除的病因及危險因素,掌握圍產期子宮切除的手術指徵、手術時機及手術方法,可減少孕產婦的發病率和死亡率。方法收集2004年6月~2014年5月本院10年內因產後出血致子宮切除的病例作出回顧性分析。結果本院10... 详细信息

目的探討嚴重產後出血致子宮切除的病因及危險因素,掌握圍產期子宮切除的手術指徵、手術時機及手術方法,可減少孕產婦的發病率和死亡率。方法收集2004年6月~2014年5月本院10年內因產後出血致子宮切除的病例作出回顧性分析。結果本院10年內分娩總人數25459人,產後出血(按胎兒娩出後24小時內出血量>500mL為標準)1186例,發生率4.66%。其中產後出血性子宮切除共12例,發生率為4.7萬分之1。病因依次為:產後宮縮乏力5例(佔41.67%)、前置胎盤3例(佔25.00%)、羊水栓塞2例(佔16.67%)、子宮破裂1例(佔8.33%)、胎盤植入1例(佔8.33%)。12例患者中行子宮次全切除術10例,子宮全切除術2例,均治癒出院。結論產後出血性子宮切除病因主要為產後宮縮乏力及前置胎盤,需時刻警惕及預防。由於產後出血的預後因失血量,失血速度及產婦體質不同而有所差異,雖然子宮切除代表永久喪失生殖能力,但卻被認為是嚴重產後出血經保守治療無效時一個金標準和挽救生命的有效方法。

关键词：產後出血圍產期子宮切除

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鏈球菌中毒休克綜合癥一例

镜湖医学 2016年第2期16卷 75-75,77页

作者：姚時賢何健菁黃耀斌黃淑健朱茜黃艷慶澳門鏡湖醫院婦產科澳門

病患者女性,36歲,因“性交後腹痛1天,發熱半天”入院,既往史體健,曾順產1胎。入院時查體T39.1℃,全腹有壓痛、反跳痛。婦科檢查:陰道膿性分泌物,宮頸光滑,舉痛,子宮如孕7週大小,壓痛,雙側附件區壓痛,未及明顯包塊。CBC:WBC:33.0×10E9/L... 详细信息

病患者女性,36歲,因“性交後腹痛1天,發熱半天”入院,既往史體健,曾順產1胎。入院時查體T39.1℃,全腹有壓痛、反跳痛。婦科檢查:陰道膿性分泌物,宮頸光滑,舉痛,子宮如孕7週大小,壓痛,雙側附件區壓痛,未及明顯包塊。CBC:WBC:33.0×10E9/L、NEU:0.982,TBIL:42.4μmol/L、DBIL:110μmol/L。B超提示:子宮肌瘤,附件未見包塊,宮後見少許液暗。腹盆腔C T示:1.子宮多發肌瘤,約0.6~2.0cm;2.下腹-盆部腹膜稍增厚;腹盆腔少量積液;3.輕度脂肪肝;4.其餘腹盆CT平掃+增強未見明顯異常。

关键词：腹盆腔盆部脂肪肝肌瘤 DBIL

Photoelectrochemical degradation of Methylene Blue with β-PbO_2 electrodes driven by visible light irradiation

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Journal of Environmental Sciences 2011年第6期23卷 998-1003页

作者： Guoting Li HoYin Yip kin Hang wong Chun Hu Jiuhui Qu Po Keung wong Department of Environmental and Municipal Engineering North China University of Water Conservancy and Electric Power Zhengzhou 450011 China School of Life Sciences The Chinese University of Hong Kong Shatin N.T. Hong Kong SAR China State Key Laboratory of Environmental Aquatic Chemistry Research Center for Eco-Environmental Sciences Chinese Academy of Sciences Beifing 100085 China

β-PbO2 electrodes were prepared by electro-deposition and characterized by scanning electron microscopy,X-ray diffraction,X-ray photoelectron spectroscopy,and linear sweep *** confirmed pure β-PbO2 crystals were on the electrode and it had a high oxygen evolution *** photoactivity and photoelectrochemical（PEC） properties of the β-PbO2 electrode were investigated under visible light irradiation（λ 〉 420 nm） for the decolorization of Methylene *** first-order kinetics parameter（Kapp） for dye decolorization using the β-PbO2 electrode achieved 6.71×10-4 min-1 under visible light irradiation,which indicated its excellent visible light-induced *** Kapp of the PEC process was as much as 1.41×10-3 min-1 and was 1.71 times that of visible light irradiation or electrolysis even in the presence of the β-PbO2 electrode.A significant synergetic effect was observed in the PEC *** also employed TiO2 modified β-PbO2 electrodes in this test,which revealed that the TiO2 immobilized on the β-PbO2 electrode inhibited the visible light-induced PEC efficiency despite the amount of TiO2 used for electrode *** β-PbO2 electrode was also superior to the dimensionally stable anode（Ti/Ru0.3Ti0.7O2） in visible light-induced photoactivity and PEC efficiency.

关键词： photocatalysis photoelectrochemical process visible light β-PbO2 electrode

Global Pediatric Pulmonology Alliance recommendation to strengthen prevention of pediatric seasonal influenza under COVID-19 pandemic

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World Journal of Pediatrics 2020年第5期16卷 433-437页

作者： Kun-Ling Shen Leyla Namazova-Baranova Yong-Hong Yang Gary Wing kin wong Lanny J.Rosenwasser Lance E.Rodewald Anne Eng Neo Goh Eitan Kerem Chris O'Callaghan T.Bernard kinane Basil Elnazir Rina Triasih Rosemary Horne Anne B Chang Jim Buttery Ruth A.Etzel Kazunobu Ouchi Hilary Hoey Varinder Singh Genesis C.Rivera Spencer SLi Yu Guan Ling Cao Yue-Jie Zheng Lu-Zhao Feng Wu Zhong Zheng-De Xie Bao-Ping Xu Rong-Jun Lin Gen Lu Qiang Qin Chun-Mei Zhu Su-Yun Qian Gang Liu Cheng-Song Zhao Zhuang Wei Yu-Hong Zhao Global Pediatric Pulmonology Alliance(GPPA)Expert Panel on Infectious Diseases&COVID-19 China National Clinical Research Center of Respiratory Diseases Department of Respiratory Medicine of Beijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijingChina Pediatrics and Child Health Research Institute Central Clinical HospitalRussian Academy of SciencesMoscowRussian Federation Department of Respiratory Shenzhen Children's HospitalShenzhenChina Chinese University of Hong Kong Hong Kong SARChina UMKC School of Medicine Kansas CityMOUSA National Immunization Program Chinese Center for Disease Control and PreventionBeijingChina K Women's and Children's Hospital SingaporeSingapore Department of Pediatrics Hadassah Hebrew University Medical CenterJerusalemIsrael UCL Great Ormond Street Institute of Child Health and Great Ormond Street Hospital(GOSH)BRC University College LondonLondonUK Massachusetts General Hospital for Children BostonMAUSA Children's Health Ireland and Trinity College Dublin DublinIreland Department of Paediatric Faculty of MedicinePublic Health and NursingUniversitas Gadjah Mada/Dr.Sardjito HospitalYogyakartaIndonesia Monash University MelbourneAustralia Queensland Children's Hospital BrisbaneAustralia Monash Children's Hospital Menzies School of Health ResearchMelbourneAustralia George Washington University WashingtonDCUSA Department of Pediatrics Kawasaki Medical SchoolKurashiki-CityJapan Department of Pediatrics University of Dublin Trinity CollegeDublinIreland Lady Hardinge Medical College and Assoc Kalawati Saran Children's Hospital New DelhiIndia Center for Medical and Allied Health Sciences New Era UniversityQuezon Citythe Philippines Global Pediatric Pulmonology Alliance Hong Kong SARChina Department of Respiratory the Children's Hospital Affiliated to the Capital Institute of PediatricsBeijingChina School of Population Medicine and Public Health Chinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina National Engineering Research Center for the Emergency Drug BeijingChina Nati

The World Health Organization(WHO)announced COVID-19 as a global pandemic in March of 2020[1].The COVID-19 pandemic may persist for a long period of *** prevention and control becomes a complex and challenging task,and such efforts should be *** general measures,such as social distancing,face masks,respiratory hygiene and hand sanitization,will bear fruits for decreasing spread of other respiratory illnesses including influenza,the specific prevention through vaccination is a key focus especially in the upcoming winter and spring seasons[2].

关键词： prevention influenza sustained