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PARAREAL ALGORITHMS APPLIED TO STOCHASTIC DIFFERENTIAL EQUATIONS WITH CONSERVED QUANTITIES

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Journal of Computational Mathematics 2019年第1期37卷 48-60页

作者： Liying Zhang weien Zhou Lihai Ji School of Mathematical Science China University of Mining and TechnologyBeijing 100083China National Innovation Institute of Defense Technology Beijing 100000China College of Science National University of Defense TechnologyChangsha 410072China Institute of Applied Physics and Computational Mathematics Beijing 100088China

In this paper,we couple the parareal algorithm with projection methods of the trajectory on a specifc manifold,defined by the preservation of some conserved quantities of stochastic differential ***,projection methods are introduced as the coarse and fine ***,we apply the projection methods for systems with conserved quantities in the correction step of original parareal ***,three mumerical experiments are performed by different kinds of algorithms to show the property of convergence in iteration,and preservation in conserved quantities of model systems.

关键词： Stochastic differential equation Parareal algorithm Conserved quantity Structurepreserving method

On the rate of convergence of two generalized Bernstein type operators

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Applied Mathematics(A Journal of Chinese Universities) 2020年第3期35卷 321-331页

作者： LIAN bo-yong CAI qing-bo Department of Mathematics Yang-En UniversityQuanzhou 362014China School of Mathematics and Computer Science Quanzhou Normal UniversityQuanzhou 362000China

In this paper,we introduce the Bézier variant of two new families of generalized Bernstein type *** establish a direct approximation by means of the Ditzian-Totik modulus of smoothness and a global approximation theorem in terms of second order modulus of *** means of construction of suitable functions and the method of bojanic and Cheng,we give the rate of convergence for absolutely continuous functions having a derivative equivalent to a bounded variation function.

关键词： Bernstein operators modulus of smoothness rate of convergence bounded variation

Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology,cognition,and behavior in APP/PS1 mice

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Neural Regeneration Research 2025年第2期20卷 533-547页

作者： Yanli Zhang Tian Li Jie Miao Zhina Zhang Mingxuan Yang Zhuoran Wang bo Yang Jiawei Zhang Haiting Li Qiang Su Junhong Guo Department of Neurology First Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Neurology Sixth Hospital of Shanxi Medical University(General Hospital of Tisco)TaiyuanShanxi ProvinceChina Department of Physiology Key Laboratory of Cellular PhysiologyMinistry of EducationShanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Hernia and Abdominal Wall Surgery Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Laboratory Medicine of Fenyang College Shanxi Medical UniversityFenyangShanxi ProvinceChina

In patients with Alzheimer’s disease,gamma-glutamyl transferase 5(GGT5)expression has been observed to be downregulated in cerebrovascular endothelial ***,the functional role of GGT5 in the development of Alzheimer’s disease remains *** study aimed to explore the effect of GGT5 on cognitive function and brain pathology in an APP/PS1 mouse model of Alzheimer’s disease,as well as the underlying *** observed a significant reduction in GGT5 expression in two in vitro models of Alzheimer’s disease(Aβ_(1-42)-treated hCMEC/D3 and bEnd.3 cells),as well as in the APP/PS1 mouse ***,injection of APP/PS1 mice with an adeno-associated virus encoding GGT5 enhanced hippocampal synaptic plasticity and mitigated cognitive ***,increasing GGT5 expression in cerebrovascular endothelial cells reduced levels of both soluble and insoluble amyloid-βin the brains of APP/PS1 *** effect may be attributable to inhibition of the expression ofβ-site APP cleaving enzyme 1,which is mediated by nuclear factor-kappa *** findings demonstrate that GGT5 expression in cerebrovascular endothelial cells is inversely associated with Alzheimer’s disease pathogenesis,and that GGT5 upregulation mitigates cognitive deficits in APP/PS1 *** findings suggest that GGT5 expression in cerebrovascular endothelial cells is a potential therapeutic target and biomarker for Alzheimer’s disease.

关键词： Alzheimer’s disease amyloid-β APP/PS1 mice cerebrovascular endothelial cells cognitive deficits gamma-glutamyl transferase 5 neurovascular unit nuclear factor‐kappa B synaptic plasticity β-site APP cleaving enzyme 1

Postnatal development of rat retina:a continuous observation and comparison between the organotypic retinal explant model and in vivo development

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Neural Regeneration Research 2025年第3期20卷 900-912页

作者： Baoqi Hu Rui Wang Hanyue Zhang Xiou Wang Sijia Zhou bo Ma Yan Luan Xin Wang Xinlin Chen Zhichao Zhang Qianyan Kang Department of Ophthalmology The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi ProvinceChina Department of Ophthalmology The First Affiliated Hospital of Northwest UniversityXi’anShaanxi ProvinceChina Institute of Neurobiology Xi’an Jiaotong University Health Science CenterXi’anShaanxi ProvinceChina

The organotypic retinal explant culture has been established for more than a decade and offers a range of unique advantages compared with in vivo experiments and cell ***,the lack of systematic and continuous comparison between in vivo retinal development and the organotypic retinal explant culture makes this model controversial in postnatal retinal development ***,we aimed to verify the feasibility of using this model for postnatal retinal development studies by comparing it with the in vivo *** this study,we showed that postnatal retinal explants undergo normal development,and exhibit a consistent structure and timeline with retinas in ***,we used SOX2 and PAX6 immunostaining to identify retinal progenitor *** then examined cell proliferation and migration by immunostaining with Ki-67 and doublecortin,***-67-and doublecortin-positive cells decreased in both in vivo and explants during postnatal retinogenesis,and exhibited a high degree of similarity in abundance and distribution between ***,we used Ceh-10 homeodomain-containing homolog,glutamate-ammonia ligase(glutamine synthetase),neuronal nuclei,and ionized calcium-binding adapter molecule 1 immunostaining to examine the emergence of bipolar cells,Müller glia,mature neurons,and microglia,*** timing and spatial patterns of the emergence of these cell types were remarkably consistent between in vivo and explant *** study showed that the organotypic retinal explant culture model had a high degree of consistency with the progression of in vivo early postnatal retina *** findings confirm the accuracy and credibility of this model and support its use for long-term,systematic,and continuous observation.

关键词： bipolar cells differentiation in vivo microglia Müller glia organotypic retinal explant culture postnatal retina development proliferation retinal progenitor cells

Anomaly monitoring and early warning of electric moped charging device with infrared image

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Optoelectronics Letters 2025年第3期 136-141页

作者： LI Jiamin HAN bo JIANG Mingshun School of Control Science and Engineering Shandong University

Potential high-temperature risks exist in heat-prone components of electric moped charging devices, such as sockets,interfaces, and controllers. Traditional detection methods have limitations in terms of real-time performance and monitoring scope. To address this, a temperature detection method based on infrared image processing has been proposed:utilizing the median filtering algorithm to denoise the original infrared image, then applying an image segmentation algorithm to divide the image.

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Effective AC Response of Nonlinear Spherical Coated Compositest

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Communications in Theoretical Physics 2004年第5期41卷 771-774页

作者： CHENXiao-Gang weien-bo SONGJin-Bao InstituteofOceanology theChineseAcademyofSciencesQingdao266071China

Under alternating current electric field, effective response of granular nonlinear composites with sphericalcoated inclusions is investigated in the dilute limit by using the perturbation approach. For an external sinusoidalapplied field with finite frequency ω, the local fields and potentials of composites in general Consist of components at allharmonics for cubic nonlinear constitutive relationships. We derive the local potentials of spherical coated composites atharmonics. Moreover, we give the formulae of the nonlinear effective AC susceptibility at the third harmonic frequency.

关键词：非线性合成非线性响应电场电流密度交流响应微扰理论

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高原环境爆炸冲击波传播规律及计算模型研究

火工品 2025年第1期 62-69页

作者：赵伟成翟红波李尚青毛伯永西安近代化学研究所陕西西安710065

为研究高原地区的低温低压环境对冲击波传播特性的影响,在海拔1500,3000,4500 m环境下开展了TNT爆炸试验,并使用有限元软件对高原环境TNT的爆炸冲击波进行数值仿真计算,分析了不同海拔对冲击波传播特性的影响规律。对比了Sadovskyi,Kinn... 详细信息

为研究高原地区的低温低压环境对冲击波传播特性的影响,在海拔1500,3000,4500 m环境下开展了TNT爆炸试验,并使用有限元软件对高原环境TNT的爆炸冲击波进行数值仿真计算,分析了不同海拔对冲击波传播特性的影响规律。对比了Sadovskyi,Kinney-Graham和Sachs修正公式的超压峰值和比冲量计算结果与试验结果,并采用Sachs修正中的温度修正项对Sadovskyi高原超压峰值公式进行了修正。研究结果表明:随着海拔的升高,冲击波的波阵面速度加快,到达时间提前,每升高1 km,冲击波超压峰值下降约2%~4%,比冲量下降约4%;对超压峰值进行修正时,3种修正公式均具有一定的准确性;对比冲量进行修正时,Kinney-Graham修正的比冲量值随比例距离增加呈线性降低,与试验结果吻合较差,庞春桥与Sachs的修正结果随比例距离增加呈指数降低;基于温度项修正的Sadovskyi高原冲击波超压峰值经验公式的平均误差减小了3.1%。该研究结果对于高海拔地区的弹药毁伤效能评估有参考意义。

关键词：爆炸试验高原环境冲击波传播特性计算模型

数字公共性:数字乡村治理共同体的建构逻辑与优化路径

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西北农林科技大学学报（社会科学版） 2025年第1期25卷 10-16页

作者：丁波安徽大学社会与政治学院合肥230039

数字乡村建设以数字技术嵌入乡村社会,改变乡村社会的结构特征与治理模式,重构乡村治理共同体,形成具有数字公共性特征的数字乡村治理共同体。数字乡村治理共同体以数字主体、数字空间和数字场景的建构逻辑,培育数字参与理念、构建数字... 详细信息

数字乡村建设以数字技术嵌入乡村社会,改变乡村社会的结构特征与治理模式,重构乡村治理共同体,形成具有数字公共性特征的数字乡村治理共同体。数字乡村治理共同体以数字主体、数字空间和数字场景的建构逻辑,培育数字参与理念、构建数字联结纽带、搭建数字交往平台,实现数字公共性生产。数字乡村治理共同体通过治理主体的行动共建、治理方式的技术共治、治理资源的利益共享,推动乡村治理的数字赋权、数字赋能、数字赋利,有助于构建人人有责、人人尽责、人人享有的数字乡村治理共同体。

关键词：数字乡村建设数字公共性乡村治理数字乡村治理共同体

Infiltration by monocytes of the central nervous system and its role in multiple sclerosis: reflections on therapeutic strategies

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Neural Regeneration Research 2025年第3期20卷 779-793页

作者： Guangyong Zhang qing Yao Chubing Long Pengcheng Yi Jiali Song Luojia Wu Wei Wan Xiuqin Rao Yue Lin Gen Wei Jun Ying Fuzhou Hua Department of Anesthesiology the Second Affiliated Hospital of Nanchang UniversityNanchangJiangxi ProvinceChina Key Laboratory of Anesthesiology of Jiangxi Province NanchangJiangxi ProvinceChina

Mononuclear macrophage infiltration in the central nervous system is a prominent feature of neuroinflammation. Recent studies on the pathogenesis and progression of multiple sclerosis have highlighted the multiple roles of mononuclear macrophages in the neuroinflammatory process. Monocytes play a significant role in neuroinflammation, and managing neuroinflammation by manipulating peripheral monocytes stands out as an effective strategy for the treatment of multiple sclerosis, leading to improved patient outcomes. This review outlines the steps involved in the entry of myeloid monocytes into the central nervous system that are targets for effective intervention: the activation of bone marrow hematopoiesis, migration of monocytes in the blood, and penetration of the blood–brain barrier by monocytes. Finally, we summarize the different monocyte subpopulations and their effects on the central nervous system based on phenotypic differences. As activated microglia resemble monocyte-derived macrophages, it is important to accurately identify the role of monocyte-derived macrophages in disease. Depending on the roles played by monocyte-derived macrophages at different stages of the disease, several of these processes can be interrupted to limit neuroinflammation and improve patient prognosis. Here, we discuss possible strategies to target monocytes in neurological diseases, focusing on three key aspects of monocyte infiltration into the central nervous system, to provide new ideas for the treatment of neurodegenerative diseases.

关键词： blood–brain barrier macrophages monocytes multiple sclerosis neuroinflammation review therapy