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Clinical application of multidisciplinary teams in tumor therapy

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Chinese Journal of Cancer Research 2017年第2期29卷 168-170页

作者： Cong wang Dongjian Song Zhili Xu jiaxiang wang School of Humanities and Social Sciences Beihang University Department of Pediatric Surgery the First Affiliated Hospital of Zhengzhou University

Multidisciplinary team （MDT） model is a diagnostic and treatment model characterized by interdisciplinarity, integration, centralism, individualization, and precision and is becoming more common in the management of complex malignancies. MDT emphasizes team spirit and a personalized treatment strategy according to the actual condition of each patient. A cooperative and effective multidisciplinary team is an important guarantee for delivering high-quality services to patients. Under the guidance of a medical humanistic concept, MDT provides reasonable, effective, convenient, and a full range of excellent quality medical service to patients. The MDT maximizes patient benefits, and it is the developmental direction for large-scale general hospitals. At the same time, the MDT is also an important measure to strengthen the core competitiveness of hospitals. Here, we introduce the clinical application of the model in tumor therapy as well as the current state and development in our hospital.

关键词： Multidisciplinary team tumor therapy clinical application

Preparation of indium tin oxide targets with a high density and single phase structure by normal pressure sintering process

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Rare Metals 2011年第2期30卷 126-130页

作者： LIU Chen LIU jiaxiang wang Yue College of Materials Science and Engineering Beijing University of Chemical Technology Beijing 100029 China

The present work mainly describes the technology for preparing indium-tin oxide （ITO） targets by cold isostatic pressing （CIP） and normal pressure sintering process. ITO powders were produced by chemical co-precipitation and shaped into an ITO green compact with a relative density of 60% by CIP under 300 MPa. Then, an ITO target with a relative density larger than 99.6% was obtained by sintering this green compact at 1550℃ for 8 h. The effects of forming pressure, sintering temperature and sintering time on the density of the target were inves- tigated. Also, a discussion was made on the sintering atmosphere.

关键词： thin films indium tin oxide (ITO) isostatic pressing sintering relative density microstructure

Mechanical response of a tunnel subjected to strike-slip faulting processes,based on a multi-scale modeling method

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Frontiers of Structural and Civil Engineering 2024年第8期18卷 1281-1295页

作者： Guoguo LIU Ping GENG Tianqiang wang Xiangyu GUO jiaxiang wang Ti DING Key Laboratory of Transportation Tunnel Engineering Ministry of EducationChengdu 610031China College of Civil Engineering Huaqiao UniversityXiamen 361021China China Railway Design Corporation Tianjin 300308China

The stick-slip action of strike-slip faults poses a significant threat to the safety and stability of underground *** this study,the north-east area of the Longmenshan fault,Sichuan,provides the geological background;the rheological characteristics of the crustal lithosphere and the nonlinear interactions between plates are described by Burger’s viscoelastic constitutive model and the friction constitutive model,respectively.A large-scale global numerical model for plate squeezing analysis is established,and the seemingly periodic stick-slip action of faults at different crust depths is *** a second model at a smaller scale,a local finite element model(sub-model),the time history of displacement at a ground level location on the Longmenshan fault plane in a stick-slip action is considered as the displacement *** integration of these models,creating a multi-scale modeling method,is used to evaluate the crack propagation and mechanical response of a tunnel subjected to strike-slip *** determinations of the recurrence interval of stick-slip action and the cracking characteristics of the tunnel are in substantial agreement with the previous field investigation and experimental results,validating the multi-scale modeling *** can be concluded that,regardless of stratum stiffness,initial cracks first occur at the inverted arch of the tunnel in the footwall,on the squeezed side under strike-slip *** smaller the stratum stiffness is,the smaller the included angle between the crack expansion and longitudinal direction of the tunnel,and the more extensive the crack expansion *** the tunnel in a high stiffness stratum,both shear and bending failures occur on the lining under strike-slip faulting,while for that in the low stiffness stratum,only bending failure occurs on the lining.

关键词： stick-slip action plate squeezing analysis multi-scale modeling method lining cracking mechanical response

MIDNet:Deblurring Network for Material Microstructure Images

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Computers, Materials & Continua 2024年第4期79卷 1187-1204页

作者： jiaxiang wang Zhengyi Li Peng Shi Hongying Yu Dongbai Sun National Center for Materials Service Safety University of Science and Technology BeijingBeijing100083China School of Materials Sun Yat-Sen UniversityShenzhen518107China School of Materials Science and Engineering Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Sun Yat-Sen UniversityGuangzhou510006China

Scanning electron microscopy(SEM)is a crucial tool in the field of materials science,providing valuable insightsinto the microstructural characteristics of ***,SEM images often suffer from blurrinesscaused by improper hardware calibration or imaging automation errors,which present challenges in analyzingand interpretingmaterial ***,rectifying the blurring of these images assumes paramountsignificance to enable subsequent *** address this issue,we introduce a Material Images DeblurringNetwork(MIDNet)built upon the foundation of the Nonlinear Activation Free Network(NAFNet).MIDNetis meticulously tailored to address the blurring in images capturing the microstructure of *** keycontributions include enhancing the NAFNet architecture for better feature extraction and representation,integratinga novel soft attention mechanism to uncover important correlations between encoder and decoder,andintroducing newmulti-loss functions to improve training effectiveness and overallmodel *** conducta comprehensive set of experiments utilizing the material blurry dataset and compare them to several state-of-theartdeblurring *** experimental results demonstrate the applicability and effectiveness of MIDNet in thedomain of deblurring material microstructure images,with a PSNR(Peak Signal-to-Noise Ratio)reaching 35.26 dBand an SSIM(Structural Similarity)of *** dataset is available at:https://***/woshigui/MIDNet.

关键词： Image deblurring material microstructure attention mechanism deep learning

Relating the probability distribution of a de Broglie wave to its phase velocity

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Chinese Science Bulletin 2012年第13期57卷 1494-1498页

作者： wang PingXiao wang jiaxiang HUO YuKun SCHEID Werner HORA Heinrich Key Laboratory of Applied Ion Beam Physics(Ministry of Education)and Institute of Modern Physics Department of Nuclear Science and TechnologyFudan UniversityShanghai 200433China State Key Laboratory of Precision Spectroscopy and Department of Physics East China Normal UniversityShanghai 200062China Institute for Theoretical Physics Justus-Liebig-UniversityGiessen D-35392Germany Department of Theoretical Physics University of New South WalesSydney 2052Australia

We show that the phase velocity in a stationary state of a de Broglie wave can be directly obtained from the probability distribution, i.e. the quantum trajectories, without detailed knowledge of the phase term itself. In other words, the amplitude of a de Broglie wave function describes not only the probability distribution but also the phase velocity distribution. Using this relationship, we comment on two calculations of the Goos-H nchen shift in de Broglie waves.

关键词：德布罗意波概率分布相速度静止状态速度分布波函数量子

Histone Deacetylation Modifier Induced One New Resorcylic Acid Lactone 7′(Z)-zeaenol from the Zoanthid-Derived Fungus Cochliobolus lunatus

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Journal of Ocean University of China 2023年第1期22卷 198-204页

作者： ZHANG Zhenkun wang jiaxiang CAO Fei ZHOU Xiaojian WU Jingshuai FU Xiumei CHEN Min wang Changyun College of Medicine and Pharmacy Ocean University of ChinaQingdao 266003China College of Environmental Science&Engineering Yangzhou UniversityYangzhou 225127China Laboratory for Marine Drugs and Bioproducts Qingdao National Laboratory for Marine Science and TechnologyQingdao 266237China College of Pharmaceutical Sciences Hebei UniversityBaoding 071002China

Chemical epigenetic manipulation was applied to the zoanthid-derived fungus Cochliobolus lunatus(TA26-46)with a histone deacetylation modifier(100μmol L^(−1) nicotinamide),resulting in the isolation of a new 14-membered resorcylic acid lactone named 7′(Z)-zeaenol(1),together with six known analogues(2−7)from the treated *** planar structure of 1 was determined by comprehensive NMR spectroscopy and HRESIMS *** absolute configuration of 1 was elucidated by ECD spectrum,^(13)C NMR shift calculations,and on the basis of biogenetic *** 5 exhibited cytotoxic activity against the human tumor cell lines A549,HCT-116,HT-29,Hela,MCF-7,and K562 with the IC_(50) values ranging from 2.54 to 7.44μmolL^(−1).

关键词： Cochliobolus lunatus 14-membered resorcylic acid lactone chemical epigenetic manipulation cytotoxic activity

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Local hardening and asymmetric twin growth by twin-twin interactions in a Mg alloy

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Journal of Magnesium and Alloys 2023年第1期11卷 176-191页

作者： Krishna Yaddanapudi Mariyappan Arul Kumar jiaxiang wang Xin wang Timothy J.Rupert Enrique J.Lavernia Julie M.Schoenung Irene J.Beyerlein Subhash Mahajan Department of Materials Science and Engineering University of CaliforniaDavisCA 95616USA Materials Science and Technology Division Los Alamos National LaboratoryLos AlamosNM 87545USA Department of Mechanical Engineering Materials DepartmentUniversity of CaliforniaSanta BarbaraCA 93106USA Department of Materials Science and Engineering University of CaliforniaIrvineUSA Materials Department University of CaliforniaSanta BarbaraCA 93106USA

In this study,the role of twin-twin interactions on the distributions of local defects(e.g.,dislocations)and stress fields in a magnesium alloy is investigated.A co-zone(1012)-(1012)tensile twin junction in a deformed Mg-3wt.%Y alloy is analyzed using transmission electron microscopy(TEM).The results show that the morphology of the impinging(1012)twin is asymmetric,and the non-interacting boundary of the recipient(1012)twin is *** analysis of TEM images reveals that type-II pyramidal[1213](1212)dislocations concentrate in the vicinity of the twin-twin junction *** samedislocations are also observed inside the interacting twin domains along with a few ***dislocations emanating from the impinging(1012)twin boundary have edge character and are extended with faults parallel to the basal *** contrast,thedislocations connected to the recipient(1012)twin are predominantly screw orientation and ***-viscoplastic fast Fourier transform based crystal plasticity calculations are performed to rationalize the observed twin morphology and local dislocation *** model calculations suggest that the local stress fields generated at the junction site where the two twins meet are responsible for the experimentally observed concentration of*** calculated stress fields are asymmetric with respect to the junction site,explaining the observed asymmetric morphology of the impinging ***,these findings show strong effects of twin-twin interactions on the distribution of dislocations as well as the evolution of the twinned microstructure and as such,can help advance understanding of twinning in Mg alloys and their effect on mechanical behavior.

关键词： Tensile twins Twin-twin intersections Mg alloys Crystal plasticity TEM

Structural evolution and bandgap modulation of layeredβ-GeSe_(2)single crystal under high pressure

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Chinese Physics B 2022年第7期31卷 428-435页

作者： Hengli Xie jiaxiang wang Lingrui wang Yong Yan Juan Guo Qilong Gao Mingju Chao Erjun Liang Xiao Ren Key Laboratory of Materials Physics of Ministry of Education School of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450052China College of Physics and Materials Science Henan Normal UniversityXinxiang 453007China

Germanium diselenide(GeSe_(2))is a promising candidate for electronic devices because of its unique crystal structure and optoelectronic ***,the evolution of lattice and electronic structure ofβ-GeSe_(2)at high pressure is still *** we prepared high-qualityβ-GeSe_(2)single crystals by chemical vapor transfer(CVT)technique and performed systematic experimental studies on the evolution of lattice structure and bandgap ofβ-GeSe_(2)under ***-precision high-pressure ultra low frequency(ULF)Raman scattering and synchrotron angle-dispersive x-ray diffraction(ADXRD)measurements support that no structural phase transition exists under high pressure up to 13.80 GPa,but the structure ofβ-GeSe_(2)turns into a disordered state near 6.91 GPa and gradually becomes amorphous forming an irreversibly amorphous crystal at 13.80 *** Raman modes keep softening abnormally upon *** bandgap ofβ-GeSe_(2)reduced linearly from 2.59 eV to 1.65 eV under pressure with a detectable narrowing of 36.5%,and the sample under pressure performs the piezochromism *** bandgap after decompression is smaller than that in the atmospheric pressure environment,which is caused by incomplete *** results enrich the insight into the structural and optical properties ofβ-GeSe_(2)and demonstrate the potential of pressure in modulating the material properties of two-dimensional(2D)Ge-based binary material.

关键词： high pressure structural phase transition Raman spectroscopy scattering layered material

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基于数据挖掘技术的税务风险检测方法评述

Engineering 2024年第3期34卷 43-59页

作者： Qinghua Zheng Yiming Xu Huixiang Liu Bin Shi jiaxiang wang Bo Dong School of Computer Science and Technology Xi’an Jiaotong UniversityXi’an 710049China Shaanxi Provincial Key Laboratory of Big Data Knowledge Engineering Xi’an Jiaotong UniversityXi’an 710049China School of Distance Education Xi’an Jiaotong UniversityXi’an 710049China

Tax risk behavior causes serious loss of fiscal revenue,damages the country’s public infrastructure,and disturbs the market economic order of fair *** recent years,tax risk detection,driven by information technology such as data mining and artificial intelligence,has received extensive *** promote the high-quality development of tax risk detection methods,this paper provides the first comprehensive overview and summary of existing tax risk detection methods *** specifi-cally,it first discusses the causes and negative impacts of tax risk behaviors,along with the development of tax risk *** then focuses on data-mining-based tax risk detection methods utilized around the *** on the different principles employed by the algorithms,existing risk detection methods can be divided into two categories:relationship-based and non-relationship-based.A total of 14 risk detection methods are identified,and each method is thoroughly explored and ***,four major technical bottlenecks of current data-driven tax risk detection methods are analyzed and discussed,including the difficulty of integrating and using fiscal and tax fragmented knowledge,unexplainable risk detection results,the high cost of risk detection algorithms,and the reliance of existing algorithms on labeled *** investigating these issues,it is concluded that knowledge-guided and datadriven big data knowledge engineering will be the development trend in the field of tax risk in the future;that is,the gradual transition of tax risk detection from informatization to intelligence is the future development direction.

关键词： Tax risk detection Data mining Knowledge guide Informatization Intellectualization