检索结果-南通市图书馆

Taxonomic dependency and spatial heterogeneity in assembly mechanisms of bacteria across complex coastal waters

Ecological Processes 2024年第1期13卷 80-97页

作者： Huizhen Yan Dandan Lin Gaoke Gu Yujie Huang Xuya Hu Zhenhao Yu Dandi Hou Demin Zhang Barbara J.Campbell kai wang State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products School of Marine SciencesNingbo University Key Laboratory of Marine Biotechnology of Zhejiang Province School of Marine Sciences Ningbo University Department of Biological Sciences Clemson University

Background Understanding community assembly mechanisms across taxa and space is fundamental for microbial ecology. However, the variability and determinants of assembly processes over taxa and space remain unclear. Here, we investigated taxonomic dependency and spatial heterogeneity in bacterial assembly mechanisms across coastal waters in the East China Sea using neutral and null models with customized visualization *** Overall, bacterial assembly mechanisms varied across broad taxonomic groups(phyla and proteobacterial classes) and space at the regional scale. A determinism–stochasticity balanced mechanism governed total bacterial assembly, while taxonomic dependency existed in assembly mechanisms and ecological processes. Among community ecological features, niche breadth and negative-to-positive cohesion ratio were strongly associated with the determinism-to-stochasticity ratio of bacterial groups. Bacterial assembly mechanisms commonly exhibited spatial heterogeneity, the extent and determinants of which varied across taxonomic groups. Spatial assembly of total bacteria was directly driven by many environmental factors and potential interactions between taxa, but not directly by geographic factors. Overall, the bacterial groups with higher spatial heterogeneity in assembly mechanisms were more related to environmental and/or geographic factors(except Bacteroidetes), while those with lower heterogeneity were more related to ecological *** Our results confirm the pervasiveness of taxonomic dependency and spatial heterogeneity in bacterial assembly, providing a finer understanding about regulation across complex coastal waters.

关键词： Bacterioplankton Assembly mechanism Niche breadth Null model Environmental gradient Biogeography

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Effect of SARS-CoV-2 infection in early pregnancy on placental development

引用

Science China(Life Sciences) 2024年第3期67卷 622-625页

作者： Shanru Yi Liping wang Mengting wang Wei Hong Ben Xu Xiaoying He Mengtian Yang Zhiping Wu Beiying wang Guang Yang Shijun Shen Xinyu Cui Ruixue wang kai wang Hong wang Xiaocui Li Shaorong Gao Cizhong Jiang Jiayu Chen Clinical and Translation Research Center of Shanghai First Maternity and Infant Hospital Shanghai Key Laboratory of Signaling and Disease ResearchSchool of Life Sciences and TechnologyTongji UniversityShanghai 200092China Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of the Ministry of Education Orthopaedic Department of Tongji HospitalTongji UniversityShanghai 200065China Frontier Science Center for Stem cell Research Tongji UniversityShanghai 200092China Shanghai Key Laboratory of Maternal Fetal Medicine Shanghai First Maternity and Infant HospitalSchool of MedicineTongji UniversityShanghai 201204China

Dear Editor,Since the COVID-19 pandemic, the potential risks associated with maternal SARS-CoV-2 infection and its effect on fetal development have been a subject of considerable public concern. Previous studies have ... 详细信息

关键词： pregnancy fetal Effect

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Energy Saving Analysis of Coal Gas Resource Utilization in Iron and Steel Enterprises

Frontiers of Metallurgical Industry

引用

Frontiers of Metallurgical Industry 2024年第2期2卷 32-36页

作者： Lu Yan kai wang MCC Huatian Engineering Technology Co. Ltd. Hebei Puyang Iron and Steel Co. Ltd.

The article discusses the preparation of a gas balance sheet,as well as the recovery,storage,transporta-tion,and use of *** analysis was conducted on the occurrence and consumption quotas of various gas media,and specific energy-saving measures were elaborated for each *** provides a theoretical reference for saving gas and reducing energy consumption in steel enterprises.

关键词： steel enterprises gas energy conservation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

“机械灌注+”应用于扩大标准供肝移植--肝尽其用

引用

Engineering 2024年第1期32卷 29-40页

作者： Zhoucheng wang Jack Martin Jiongjie Yu kai wang Kourosh Saeb-Parsy Xiao Xu Zhejiang University School of Medicine Hangzhou 310058China Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province Hangzhou 310006China Department of Surgery Cambridge University Hospitals&NHS Foundation TrustCambridge CB22QQ UK Department of Surgery University of Cambridge&NIHR Cambridge Biomedical Research CentreCambridge CB22QQUK Institute of Organ Transplantation Zhejiang UniversityHangzhou 310003China

Transplantation represents the most effective treatment for end-stage liver diseases but is limited by the shortage of healthy donor *** criteria donor(ECD)liver grafts are increasingly utilized in clinical practice to mitigate this ***,impaired ischemic tolerance of these grafts jeopardizes organ viability during cold *** perfusion(MP)was designed to improve organ preservation and reduce posttransplant ***,it is increasingly evident that MP alone may not preserve ECD grafts *** emphasis has thus been placed on modified MP strategies,including the use of different perfusates,modified perfusion modalities,and different therapeutic ***,we introduce a novel term,"MP Plus,"denoting these additional strategies that are designed to restore organ function and potentially enable regeneration of ECD *** this review,we summarize the existing and potential modified MP strategies and discuss their advantages in reconditioning different ECD grafts in clinical settings.

关键词： Liver transplantation Extended criteria donor Machine perfusion plus Organ shortage

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Prohibitin 1 inhibits cell proliferation and induces apoptosis via the p53-mediated mitochondrial pathway in vitro

引用

World Journal of Gastrointestinal Oncology 2024年第2期16卷 398-413页

作者： Juan-Juan Shi Yi-kai wang Mu-Qi wang Jiang Deng Ning Gao Mei Li Ya-Ping Li Xin Zhang Xiao-Li Jia Xiong-Tao Liu Shuang-Suo Dang Wen-Jun wang Department of Infectious Diseases The Second Affiliated Hospital of Xi’an Jiaotong UniversityXi'an 710004Shaanxi ProvinceChina Department of Operating Room The Second Affiliated Hospital of Xi’an Jiaotong UniversityXi'an 710004Shaanxi ProvinceChina

BACKGROUND Prohibitin 1(PHB1)has been identified as an antiproliferative protein that is highly conserved and ubiquitously expressed,and it participates in a variety of essential cellular functions,including apoptosis,cell cycle regulation,prolifera-tion,and *** evidence indicates that PHB1 may play an important role in the progression of hepatocellular carcinoma(HCC).However,the role of PHB1 in HCC is *** To investigate the effects of PHB1 on the proliferation and apoptosis of human HCC cells and the relevant mechanisms in *** HCC patients and healthy individuals were enrolled in this study according to the inclusion and exclusion criteria;then,PHB1 levels in the sera and liver tissues of these participates were determined using ELISA,RT-PCR,and *** HepG2 and SMMC-7721 cells were transfected with the pEGFP-PHB1 plasmid and PHB1-specific shRNA(shRNA-PHB1)for 24-72 *** prolif-eration was analysed with an MTT *** cycle progression and apoptosis were analysed using flow cytometry(FACS).The mRNA and protein expression levels of the cell cycle-related molecules p21,Cyclin A2,Cyclin E1,and CDK2 and the cell apoptosis-related molecules cytochrome C(Cyt C),p53,Bcl-2,Bax,caspase 3,and caspase 9 were measured by real-time PCR and Western blot,*** Decreased levels of PHB1 were found in the sera and liver tissues of HCC patients compared to those of healthy individuals,and decreased PHB1 was positively correlated with low differentiation,TNM stage III-IV,and alpha-fetoprotein≥400μg/*** of PHB1 significantly inhibited human HCC cell proliferation in a time-dependent *** revealed that the overexpression of PHB1 arrested HCC cells in the G0/G1 phase of the cell cycle and induced *** proportion of cells in the G0/G1 phase was significantly increased and the proportion of cells in the S phase was decreased in HepG2 cells that were transfected with pEGFP-PHB1 compar

关键词： Prohibitin 1 Hepatocellular carcinoma cells Apoptosis Cell cycle Mitochondrial pathway

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Influence of sex on outcomes of liver transplantation for hepatocellular carcinoma:a multicenter cohort study in China

引用

Cancer Biology & Medicine 2024年第4期21卷 347-362页

作者： Jian Chen Zhe Yang Fengqiang Gao Zhisheng Zhou Junli Chen Di Lu kai wang Meihua Sui Zhengxin wang Wenzhi Guo Guoyue Lyu Haizhi Qi Jinzhen Cai Jiayin Yang Shusen Zheng Xiao Xu Zhejiang University School of Medicine Hangzhou 310030China Institute of Organ Transplantation Zhejiang UniversityHangzhou 310030China Department of Hepatobiliary and Pancreatic Surgery Shulan Hospital of HangzhouHangzhou 310006China National Center for Healthcare Quality Management in Liver Transplant Hangzhou 310003China Department of General Surgery Huashan HospitalFudan UniversityShanghai 200040China Department of Hepatobiliary and Pancreatic Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Department of Hepatobiliary and Pancreatic Surgery The First Hospital of Jilin UniversityChangchun 130021China Department of Liver Transplantation Second Xiangya HospitalCentral South UniversityChangsha 410008China Department of Organ Transplantation Center The Affiliated Hospital of Qingdao UniversityQingdao 266003China Department of Liver Surgery and Liver Transplantation Center West China HospitalSichuan UniversityChengdu 610044China NHC Key Laboratory of Combined Multi-organ Transplantation Hangzhou 310003China Department of Hepatobiliary and Pancreatic Surgery The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China

Objective:Sex-specific differences are observed in various liver diseases,but the influence of sex on the outcomes of hepatocellular carcinoma(HCC)after liver transplantation(LT)remains to be *** study is the first Chinese nationwide investigation of the role of sex in post-LT outcomes in patients with ***:Data for recipients with HCC registered in the China Liver Transplant Registry between January 2015 and December 2020 were *** associations between donor,recipient,or donor-recipient transplant patterns by sex and the post-LT outcomes were studied with propensity score matching(PSM).The survival associated with different sex-based donor-recipient transplant patterns was further ***:Among 3,769 patients enrolled in this study,the 1-,3-,and 5-year overall survival(OS)rates of patients with HCC after LT were 96.1%,86.4%,and 78.5%,respectively,in female recipients,and 95.8%,79.0%,and 70.7%,respectively,in male recipients after PSM(P=0.009).However,the OS was comparable between recipients with female donors and male *** analysis indicated that male recipient sex was a risk factor for post-LT survival(HR=1.381,P=0.046).Among the donor-recipient transplant patterns,the male-male donor-recipient transplant pattern was associated with the poorest post-LT survival(P<0.05).Conclusions:Our findings highlighted that the post-LT outcomes of female recipients were significantly superior to those of male recipients,and the male-male donor-recipient transplant pattern was associated with the poorest post-LT *** from male donors may provide the most benefit to female *** results indicate that sex should be considered as a critical factor in organ allocation.

关键词： Sex liver transplantation hepatocellular carcinoma outcome recipient donor

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

生命、价值与自我——儒家亲子伦理的价值基础及其现代境遇

引用

孔子研究 2024年第3期 5-17,157页

作者：王楷北京师范大学哲学学院北京100875

本着一种祛魅而不解构的理论自觉,在现代性视角之下审视并重理儒家亲子伦理的价值基础。传统儒家孝道以亲生子这一自然事实作为存在论基础,如此,亲子一体不仅在发生学上解释了一个人之所由来,更在价值上规定了一个人之所应是。这也意味... 详细信息

本着一种祛魅而不解构的理论自觉,在现代性视角之下审视并重理儒家亲子伦理的价值基础。传统儒家孝道以亲生子这一自然事实作为存在论基础,如此,亲子一体不仅在发生学上解释了一个人之所由来,更在价值上规定了一个人之所应是。这也意味着人子的道德自我是先天受限的、残缺的,从而在实践层面可能造成“从父”与“从义”之间的紧张。在现代性视角之下,仅仅基于亲生子这一生理事件的孝道只是干瘪的生殖崇拜,并不足以从自然推出价值。较之传统孝道强调亲生子这一自然事实的本体论意义,更应看重亲子伦理的生成性(“父父,子子”),如此方可在自我与“一体”之间寻找一种恰当的平衡。

关键词：生命价值自我孝一体

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

“王权至尊”的真伪之辩与合法性叙事——以莫尔与圣·杰曼的论战为中心

引用

北京大学学报（哲学社会科学版） 2024年第3期61卷 166-174页

作者：王凯华南理工大学法学院广州510006

“王权至尊”作为英格兰脱离普世基督教帝国的合法性叙事,被视作英格兰主权国家的理论表达。但现有研究并不重视都铎政府高层对其的反对意见。莫尔因拒绝对《继承法案》宣誓而遭受叛国罪审判时,就已阐明“王权至尊”真实性的缺陷。在此... 详细信息

“王权至尊”作为英格兰脱离普世基督教帝国的合法性叙事,被视作英格兰主权国家的理论表达。但现有研究并不重视都铎政府高层对其的反对意见。莫尔因拒绝对《继承法案》宣誓而遭受叛国罪审判时,就已阐明“王权至尊”真实性的缺陷。在此之前莫尔还就教会成员构成、教会本质及议会立法权等问题与圣·杰曼展开论战。上述问题正是莫尔判断“王权至尊”真实性的“前理解”。圣·杰曼认为教会是神职人员与平信徒的集合体,并将“王在议会”作为英格兰王国整体性的代表等同于王国的至高性,从而主张议会具有管辖教会并授予国王教会领袖的权力。但“王在议会”的模糊性也决定了“王权至尊”只能证成英格兰脱离大公教会的合法性,却无法明确本土属灵事务的管辖权究竟归属于国王本人或议会。

关键词： “王权至尊” 莫尔与圣·杰曼的论战政教关系亨利八世宗教改革

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

论备案审查中法院申请审查的条件和路径

引用

浙江社会科学 2024年第8期 75-85,158页

作者：王锴北京航空航天大学法学院北京100191

2023年12月,全国人大常委会通过的《关于完善和加强备案审查制度的决定》规定了法院在审判工作中发现法规、司法解释同宪法、法律相抵触或者存在合宪性、合法性问题的,可以逐级上报至最高人民法院向全国人大常委会提出书面审查要求的制... 详细信息

2023年12月,全国人大常委会通过的《关于完善和加强备案审查制度的决定》规定了法院在审判工作中发现法规、司法解释同宪法、法律相抵触或者存在合宪性、合法性问题的,可以逐级上报至最高人民法院向全国人大常委会提出书面审查要求的制度,该规定激活了法院在备案审查中的角色,有必要进行细化。通过参考德国的具体审查和法国的合宪性问题移送制度,未来我国法院申请备案审查的条件包括:(1)该法规、司法解释属于案件的裁判依据;(2)法院怀疑其与宪法、法律相抵触或者存在合宪性、合法性的疑虑;(3)法院在提起申请前要经过本院审判委员会的同意;(4)法院应当提交书面申请并附理由。法院申请备案审查的路径包括逐级上报和直接向全国人大常委会提出审查建议两种,以此来更好地实现法院在维护国家法制统一中的作用。

关键词：具体审查备案审查裁判重要性逐级上报溯及力

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

人民检察院法律监督的体系分析

引用

法学研究 2024年第1期46卷 39-54页

作者：王锴北京航空航天大学法学院

法律监督是在当代中国宪法制度和实践中生成的标志性概念。从一般监督理念的确立,到一般监督不被强调直至被取消,再到一般监督理念的回归,具有中国特色的法律监督概念日渐成熟。要系统全面地把握中国法治理论与实践中的法律监督概念,有... 详细信息

法律监督是在当代中国宪法制度和实践中生成的标志性概念。从一般监督理念的确立,到一般监督不被强调直至被取消,再到一般监督理念的回归,具有中国特色的法律监督概念日渐成熟。要系统全面地把握中国法治理论与实践中的法律监督概念,有必要从宪法所构建的监督体系入手,理顺法律监督与宪法上其他监督之间的关系、法律监督与检察权之间的关系,以及法律监督与检察一体、独立行使检察权原则之间的关系。不同于宪法上明示或隐含的其他监督类型,人民检察院法律监督的监督内容只包括合法性,监督手段侧重程序性,监督方式强调与办案相结合。法律监督是检察权的本质属性,检察权指的就是检察机关所行使的法律监督权。宪法同时规定了检察一体原则和独立行使检察权原则,这两者之间存在张力,但都必须朝着有利于开展法律监督的方向发展。

关键词：法律监督检察权一般监督检察一体独立行使检察权

来源：

维普期刊数据库

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：