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中西医结合治疗椎基底动脉扩张延长症合并缺血性卒中1例

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中国中西医结合杂志 2024年第3期44卷 369-372页

作者：王一战姬旭陈鹏刘慧林刘清泉王鑫郭妍刘宏伟首都医科大学附属北京中医医院针灸中心北京100010 北京中医医院顺义医院脑病科北京101399

椎基底动脉扩张延长症(vertebrobasilar dolichoectasia,VBD)是一种以椎动脉颅内段和(或)基底动脉显著扩张、延长、迂曲为特征,属于少见的不可逆的颅内血管病变。VBD合并缺血性脑卒中综合预后不良,现代医学在治疗上存在争议,常规剂量的... 详细信息

椎基底动脉扩张延长症(vertebrobasilar dolichoectasia,VBD)是一种以椎动脉颅内段和(或)基底动脉显著扩张、延长、迂曲为特征,属于少见的不可逆的颅内血管病变。VBD合并缺血性脑卒中综合预后不良,现代医学在治疗上存在争议,常规剂量的抗血小板聚集或抗凝治疗,可能增加脑出血风险[1]。本例患者运用中西医结合的治疗方式,日常生活能力明显改善,正常回归社会,取得满意疗效,现报道如下。病例简介患者男,45岁,因“突发右侧肢体力弱伴语言不利17 h”于2022年10月4日就诊于北京中医医院急诊。患者17 h前(2022年10月3日21时)安静状态下出现右侧肢体力弱,行走右偏,语言欠流利,未重视及就诊。后上述症状进展加重,右侧肢体抬举费力,行走拖沓、语言含糊明显,右侧口角下垂,于北京中医医院急诊完善脑MRI结果提示:(1)左侧桥脑脑梗死(急性期)可能性大;(2)基底动脉延长扩张症可能(图1)。

关键词：北京中医医院椎基底动脉扩张延长症口角下垂缺血性卒中安静状态颅内血管病变日常生活能力预后不良

不同植物对体外瘤胃发酵产气量和甲烷产量的影响

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饲料研究 2024年第10期47卷 93-98页

作者：刘尚王占义李琪宁玉娜刘海洋张梓婷李宏宇王成杰内蒙古农业大学草原与资源环境学院内蒙古呼和浩特010018 内蒙古农业大学草地资源教育部重点实验室内蒙古呼和浩特010018

试验旨在研究不同植物对体外瘤胃总产气量(GP)和甲烷(CH_(4))产量的影响。试验以11种植物的枝叶为材料,进行体外发酵培养,测定体外发酵24 h后的GP和CH_(4)产量。结果表明:在4种灌木、半灌木牧草中,紫丁香的GP最高;在多年生牧草中,紫花... 详细信息

试验旨在研究不同植物对体外瘤胃总产气量(GP)和甲烷(CH_(4))产量的影响。试验以11种植物的枝叶为材料,进行体外发酵培养,测定体外发酵24 h后的GP和CH_(4)产量。结果表明:在4种灌木、半灌木牧草中,紫丁香的GP最高;在多年生牧草中,紫花苜蓿、黄花苜蓿、百脉根、野大豆GP显著高于野豌豆、沙打旺和野艾蒿(P<0.05);紫丁香和冷蒿的CH_(4)产量低于达乌里胡枝子和百里香。紫丁香和野豌豆能够减少CH_(4)产量,提高微生物蛋白(MCP)含量。紫丁香、黄花苜蓿和野豌豆的总皂苷、生物碱含量与GP呈正相关,与CH_(4)呈负相关。研究表明,紫丁香、野豌豆和黄花苜蓿可以作为优质的饲料添加剂,调控反刍家畜瘤胃产气特征。

关键词：体外发酵产气量甲烷

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“调神”思想在针灸临床中的运用概况及规律探讨

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针刺研究 2024年第8期49卷 867-874页

作者：曾宇涵付渊博李彬袁芳赵冰骢王一战宋玉强李柏洁沈琳博首都医科大学附属北京中医医院针灸科针灸神经调控北京市重点实验室北京100010

“神”在疾病治疗过程中所发挥的积极作用一直受到中医学者的重视,“调神”被认为是中医疗法的核心精髓所在。针灸调神作为一种身心并治的治疗手段,与当前的生物-心理-社会医学模式不谋而合。近年来,大量临床研究证实了针灸调神法的确... 详细信息

“神”在疾病治疗过程中所发挥的积极作用一直受到中医学者的重视,“调神”被认为是中医疗法的核心精髓所在。针灸调神作为一种身心并治的治疗手段,与当前的生物-心理-社会医学模式不谋而合。近年来,大量临床研究证实了针灸调神法的确切疗效。本文梳理近10年针灸调神法在精神心理疾病、神经系统疾病和消化系统疾病中的临床应用情况,简要总结多种针灸调神疗法的研究进展,探求通督调神法、疏肝调神法和“调神针法”的理论内涵,分析针灸调神的主要选穴规律,并为进一步完善针灸调神法的临床应用理论依据提出发展方向。

关键词：针灸调神临床应用

Reducing the voltage loss of Y-series acceptor based organic solar cells via ternary/quaternary strategies

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Chinese Chemical Letters 2024年第2期35卷 70-86页

作者： Pengyu zhang Zhiyang zhang Heng Sun Jie Li yi Chen Jiang wang Chuanlang zhan Key Laboratory of Advanced Materials Chemistry and Devices (AMC&DLab) of the Department of Education of Inner Mongolia Autonomous Region Inner Mongolia Key Laboratory of Green CatalysisCollege of Chemistry and Environment ScienceInner Mongolia Normal UniversityHuhehot 010022China

In recent years, with the emergence of non-fullerene fused-ring acceptors, power conversion efficiencies (PCEs) of organic solar cells (OSCs) have exceeded 19%.However, compared to inorganic or perovskite photovoltaic cells, a higher voltage loss has become one of the key factors limiting further improvement in the PCEs of *** ternary/quaternary strategy has been identified as a feasible and effective way to obtain high-efficiency *** this review, a brief outline is given of the key roles that guest materials played in reducing voltage losses in solar cell devices and a brief look at the future material design and the design of ternary/quaternary systems.

关键词： Organic solar cell Ternary/quaternary strategy Open-circuit voltage Voltage loss Non-radiative recombination loss

Lithium Sulfur Batteries:Insights from Solvation Chemistry to Feasibility Designing Strategies for Practical Applications

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Energy & Environmental Materials 2024年第4期7卷 5-27页

作者： Jian Tan Longli Ma Yuan wang Pengshu yi Chuming Ye zhan Fang Zhiheng Li Mingxin Ye Jianfeng Shen Institute of Special Materials and Technology Fudan University Department of Materials Science Fudan University Department of Chemistry Fudan University

Rechargeable lithium-sulfur (Li-S) batteries,featuring high energy density,low cost,and environmental friendliness,have been dubbed as one of the most promising candidates to replace current commercial rechargeable Li-ion ***,their practical deployment has long been plagued by the infamous"shuttle effect"of soluble Li polysulfides (LiPSs) and the rampant growth of Li dendrites.

关键词： characterization tools design strategies Li–S batteries practical applications solvation chemistry

Displacement-pressure biparametrically regulated softness sensory system for intraocular pressure monitoring

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National Science Review 2024年第6期11卷 159-168页

作者： Yu Cheng yifei zhan Fangyi Guan Junli Shi Jingxiao wang yi Sun Muhammad Zubair Cunjiang Yu Chuan Fei Guo Department of Materials Science and Engineering Southern University of Science and Technology Department of Engineering Science and Mechanics Pennsylvania State University Department of Biomedical Engineering Pennsylvania State University Department of Materials Science and Engineering Materials Research Institute Pennsylvania State University

High intraocular pressure(IOP) is one of the high-risk pathogenic factors of glaucoma. Existing methods of IOP measurement are based on the direct interaction with the cornea. Commercial ophthalmic tonometers based on snapshot measurements are expensive, bulky, and their operation requires trained *** contact lenses are easy to use, but they may block vision and cause infection. Here, we report a sensory system for IOP assessment that uses a soft indentor with two asymmetrically deployed iontronic flexible pressure sensors to interact with the eyelid-eyeball in an eye-closed situation. Inspired by human fingertip assessment of softness, the sensory system extracts displacement-pressure information for soft evaluation, achieving high accuracy IOP monitoring(>96%). We further design and custom-make a portable and wearable ophthalmic tonometer based on the sensory system and demonstrate its high efficacy in IOP screening. This sensory system paves a way towards cost-effective, robust, and reliable IOP monitoring.

关键词： intraocular pressure tonometer deep learning softness iontronic sensor

Miniaturized, Shared Electric and Magnetic Dipole, Pattern Diversity IoT Antenna for Sub-6 GHz Applications

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Chinese Journal of Electronics 2024年第5期33卷 1224-1233页

作者： zhan wang Yuandan DONG University of Electronic Science and Technology of China

By using a novel meta-resonator structure, a miniaturized, surface mountable, shared aperture, and hybrid electric/magnetic dipole pattern diversity antenna is proposed for Internet of things（IoT） applications. By exploring the shared electric（E-dipole） and magnetic dipole（M-dipole） structures, a novel T-shaped split-ring resonator（SRR） with even and odd modes is presented and studied by current distributions and equivalent *** and omnidirectional（monopole-like） patterns are achieved by exciting the M-dipole and E-dipole modes of the T-shaped SRR, respectively. To validate the proposed design, this shared aperture metamaterial-inspired pattern diversity antenna with a small size of 0.295λ0× 0.0065λ0× 0.115λ0is fabricated and measured. The measured overlapped-10 dB bandwidth is from 3.40 GHz to 3.63 GHz（7.0%, covering the LTE B42 band） and the port isolation is greater than 23 dB. Both two modes achieve a good radiation efficiency better than-0.79 d B（>83.0%）.

关键词： Antenna measurements Dipole antennas Surface mount technology Switches Size measurement Aperture antennas Internet of Things Electric/magnetic dipoles Internet of things (IoT) Metamaterial-based/inspired antenna LOW-PROFILE PATCH ANTENNA RECONFIGURABLE ANTENNA MICROSTRIP ANTENNA RADIATION-PATTERN HIGH-GAIN FREQUENCY ARRAY

Establishment of NaLuF_(4):15%Tb-based low dose X-PDT agent and its application on efficient antitumor therapy

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International Journal of Minerals,Metallurgy and Materials 2024年第3期31卷 599-610页

作者： yi Tian Zhiguang Fu Xiaosheng Zhu Chunjing zhan Jinwei Hu Li Fan Chaojun Song Qian Yang Yu wang Mei Shi Department of Radiation Oncology Xijing HospitalThe Fourth Military Medical UniversityXi’an 710032China Department of Oncology Air Force Medical CenterPLAThe Fourth Military Medical UniversityBeijing 100142China Department of Tumor Radiotherapy Air Force Medical CenterPLAThe Fourth Military Medical UniversityBeijing 100142China Department of Gastroenterology Air Force Hospital of Southern Theater CommandGuangzhou 510062China Department of Pharmaceutical Chemistry and Analysis School of PharmacyThe Fourth Military Medical UniversityXi’an 710032China School of Life Sciences Northwestern Polytechnical UniversityXi’an 710072China Institue of Materia Medica School of PharmacyThe Fourth Military Medical UniversityXi’an 710032China

X-ray excited photodynamic therapy(X-PDT)is the bravo answer of photodynamic therapy(PDT)for deep-seated tumors,as it employs X-ray as the irradiation source to overcome the limitation of light penetration ***,high X-ray irradiation dose caused organ lesions and side effects became the major barrier to X-PDT *** address this issue,this work employed a classic-al co-precipitation reaction to synthesize NaLuF_(4):15%Tb^(3+)(NLF)with an average particle size of(23.48±0.91)nm,which was then coupled with the photosensitizer merocyanine 540(MC540)to form the X-PDT system NLF-MC540 with high production of singlet *** system could induce antitumor efficacy to about 24%in relative low dose X-ray irradiation range(0.1-0.3 Gy).In vivo,when NLF-MC540 irradiated by 0.1 Gy X-ray,the tumor inhibition percentage reached 89.5%±5.7%.The therapeutic mechanism of low dose X-PDT was found.A significant increase of neutrophils in serum was found on the third day after *** immunohistochemical staining of tumor sections,the Ly6G^(+),CD8^(+),and CD11c^(+)cells infiltrated in the tumor microenvironment were *** the bilat-eral tumor model,the NLF-MC540 with 0.1 Gy X-ray irradiation could inhibit both the primary tumor and the distant tumor ***-tected by enzyme linked immunosorbent assay(ELISA),two cytokines IFN-γand TNF-αin serum were upregulated 7 and 6 times than negative control,*** by enzyme linked immune spot assay(ELISPOT),the number of immune cells attributable to the IFN-γand TNF-αlevels in the group of low dose X-PDT were 14 and 6 times greater than that in the negative control group,***,it conclude that low dose X-PDT system could successfully upregulate the levels of immune cells,stimulate the secretion of cy-tokines(especially IFN-γand TNF-α),activate antitumor immunity,and finally inhibit colon tumor growth.

关键词： X-ray excited photodynamic therapy singlet oxygen low dose X-Ray irradiation efficient antitumor therapy anti-tumor immunity

Experimental investigation of engineered geopolymer composite for structural strengthening against blast loads

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Defence Technology（防务技术） 2024年第2期32卷 496-509页

作者： Shan Liu Chunyuan Liu yifei Hao yi zhang Li Chen zhan Li Key Laboratory of Coast Civil Structure Safety of Ministry of Education Tianjin UniversityTianjin 300072China Tianjin Key Laboratory of Prefabricated Buildings and Intelligent Construction Hebei University of TechnologyTianjin 300400China Institute of Defense Engineering AMSPLABeijing 100850China Engineering Research Center of Safety and Protection of Explosion&Impact of Ministry of Education Southeast UniversityNanjing 211189JiangsuChina State Key Laboratory of Disaster Prevention&Mitigation of Explosion&Impact Army Engineering University of the PLANanjing 210007JiangsuChina

The recent increase in blast/bombing incidents all over the world has pushed the development of effective strengthening approaches to enhance the blast resistance of existing civil *** geopolymer composite(EGC)is a promising material featured by eco-friendly,fast-setting and strain-hardening characteristics for emergent strengthening and ***,the fiber optimization for preparing EGC and its protective effect on structural elements under blast scenarios are *** this study,laboratory tests were firstly conducted to evaluate the effects of fiber types on the properties of EGC in terms of workability,dry shrinkage,and mechanical properties in compression,tension and *** experimental results showed that EGC containing PE fiber exhibited suitable workability,acceptable dry shrinkage and superior mechanical properties compared with other types of *** that,a series of field tests were carried out to evaluate the effectiveness of EGC retrofitting layer on the enhancement of blast performance of typical *** tests include autoclaved aerated concrete(AAC)masonry walls subjected to vented gas explosion,reinforced AAC panels subjected to TNT explosion and plain concrete slabs subjected to contact *** was found that EGC could effectively enhance the blast resistance of structural elements in different *** AAC masonry walls and panels,with the existence of EGC,the integrity of specimens could be maintained,and their deflections and damage were significantly *** plain concrete slabs,the EGC overlay could reduce the diameter and depth of the crater and spallation of specimens.

关键词： Engineered geopolymer composites Fiber optimization Strengthening material Blast resistance Masonry wall Reinforced AAC panel Plain concrete slab