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International Journal of Minerals,Metallurgy and Materials 2023年第6期30卷 1128-1139页

作者： Dong wang Chen Ma Jinyu liu Weidong li Wei Shang ning peng Yuqing Wen Guangxi Key Laboratory of Electrochemical and Magnetochemical Function Materials College of Chemistry and BioengineeringGuilin University of TechnologyGuilin 541004China

Magnesium(Mg)alloys,the lightest metal construction material used in industry,play a vital role in future ***,the poor corrosion resistance of Mg alloys in corrosion environments largely limits their potential wide ***,a micro-arc oxidation/graphene oxide/stearic acid(MAO/GO/SA)superhydrophobic composite coating with superior corrosion resistance was fabricated on a Mg alloy AZ91D through micro-arc oxidation(MAO)technology,electrodeposition technique,and self-assembly *** composition and microstructure of the coating were characterized by scan{2. electron microscopy,X-ray diffraction,energy dispersive spectroscopy,and Raman *** effective protection of the MAO/GO/SA composite coating applied to a substrate was evaluated using potentiodynamic polarization,electrochemical impedance spectroscopy tests,and salt spray *** results showed that the MAO/GO/SA composite coating with a petal spherical structure had the best superhydrophobicity,and it attained a contact angle of 159.53°±2..The MAO/GO/SA composite coating exhibited high resistance to corrosion,according to electrochemical and salt spray tests.

关键词： magnesium alloy composite coating superhydrophobic corrosion resistance anti-soiling performance

Designing Unpowered Shoulder Complex Exoskeleton via Contralateral Drive for Self-rehabilitation of Post-stroke Hemiparesis

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Journal of Bionic Engineering 2023年第3期20卷 992-1007页

作者： ning li Tie Yang Yang Yang Wenyuan Chen {2. Yu Chuang Zhang ning Xi Ying Zhao Wenxue wang State Key Laboratory of Robotics Shenyang Institute of AutomationChinese Academy of SciencesShenyang110016China Institutes for Robotics and Intelligent Manufacturing Chinese Academy of SciencesShenyang110169China university of Chinese Academy of sciences Beijing100049China Emerging Technologies Institute Department of Industrial and Manufacturing Systems EngineeringUniversity of Hong KongPokfulamHong Kong999077China Department of General Surgery Shengjing Hospital of China Medical UniversityShenyang110004China

Rehabilitation using exoskeleton robots can effectively remediate dysfunction and restore post-stroke survivors’ physical ability. However, low kinematic compatibility and poor self-participation of post-stroke patients in rehabilitation restrict the outcomes of exoskeleton-based therapy. The study presents an Unpowered Shoulder Complex Exoskeleton (USCE), consisting of Shoulder Girdle Mechanism (SGM), Ball-and-Socket Joint Mechanism (BSM), Gravity Compensating Mechanism (GCM) and Adjustable Alignment Design (AAD), to achieve self-rehabilitation of shoulder via energy transfer from the healthy upper limb to the affected counterpart of post-stroke hemiplegic patients. The SGM and AAD are designed to improve the kinematic compatibility by compensating for displacements of the glenohumeral joint with the adaptable size of USCE for different wearers. The BSM and GCM can transfer the body movement and energy from the healthy half of the body to the affected side without external energy input and enhance the self-participation with sick posture correction. The experimental results show that the USCE can provide high kinematic compatibility with 90.9% movement similarity between human and exoskeleton. Meanwhile, the motion ability of a post-stroke patient’s affected limb can be increased through energy transfer. It is expected that USCE can improve outcomes of home-based self-rehabilitation.

关键词： Unpowered exoskeleton Health-paralysis combination Energy transfer Self-rehabilitation Shoulder mechanism design

Crystal structure of a novel two-dimensional supramolecular network based on polyoxoanion and yttrium~Ⅲcoordination cation

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Science china Chemistry 2005年第z1期48卷 9-13页

作者： HE Shuiyang,peng Ke,ning Wei,{2. Daqi & SHI Qizhen Department of Chemistry,Northwest university and Shaanxi Key Laboratory of Physico-Inorganic Chemistry,Xi’an 710069,china College of Chemistry and Chemical Engineering,liaocheng university,liaocheng 2.2.59,china 1. Department of Chemistry Northwest University and Shaanxi Key Laboratory of Physico-Inorganic Chemistry 710069 Xi’an China 2. College of Chemistry and Chemical Engineering Liaocheng University 252059 Liaocheng China

A novel compound (NH4)2.(H2.)8[PMo10V2.40]·10H2. has been prepared in an aqueous solution and characterized by elemental analysis, IR, and TG-DTG analysis. X-ray diffraction analysis was carried out on (NH4)2.(H2.)8 [PMo10V2.40]·10H2. single crystal, which crystallizes in the monoclinic system of a space group P2./C with a=0.9871(3) nm,b=1.542.(5) nm,c=2.792.(9) nm,β=94.183(5)°and Z=2. In the compound, a two-dimensional network is constructed by the PMo10V2.405- anion and the Y(H2.)83+ cation building blocks via hydrogen bonding exhibiting the porous structure.

关键词： crystal structure, polyoxoanion, yttrium, supramolecular network.

高通量测序数据再分析在识别结直肠癌患者ERBB2.增中的价值

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复旦学报（医学版） 2024年第2期51卷 166-171页

作者：沈敏娜张丽陈馨宁黄斐白超刚陈丽萌彭海翔周琰王蓓丽潘柏申郭玮复旦大学附属中山医院检验科上海200032 复旦大学附属中山医院厦门医院检验科厦门361015 上海市宝山区吴淞中心医院检验科上海200940 上海市老年医学中心检验科上海201104 上海顿慧医疗科技发展有限公司上海201615

目的评估未涵盖即ERBB2.贝数变异(copynumbervariation,CNV)分析的高通量测序(highthroughput sequencing,HTS)数据再分析在识别结直肠癌患者ERBB2.增中的价值。方法回顾性分析经病理活检确诊为结直肠癌并接受外周血cfDNA高通量测序... 详细信息

目的评估未涵盖即ERBB2.贝数变异(copynumbervariation,CNV)分析的高通量测序(highthroughput sequencing,HTS)数据再分析在识别结直肠癌患者ERBB2.增中的价值。方法回顾性分析经病理活检确诊为结直肠癌并接受外周血cfDNA高通量测序样本的检测数据2.2.。根据经免疫组织化学(immunohistochemistry,IHC)和/或荧光原位杂交(fluorescence in situ hybridization,FISH)判断为ERBB2.扩增样本的HTS数据,计算17号染色体(Chr17)reads数占总reads数的比例范围,初步确定其为识别ERBB2.增的阈值。根据初步阈值筛选可疑阳性样本,通过数字PCR、IHC和FISH进行验证。结果89例经IHC和/或FISH判定为ERBB2.扩增样本的Chr17 reads数与总reads数的比值为0.2.9±0.192.0.188~0.2.9)。以均数的1.2.倍0.2.8作为识别ERBB2.增的阈值分析其余163例样本数据,发现7例疑似阳性,比值为0.302.0.853。其中5例经IHC和/或FISH判定为阳性,6例经数字PCR验证为阳性,Chr17 reads与总reads数的比值与ERBB2.EIF2.1比值成正相关,相关性好(r2.0.909)。结论再分析未涵盖ERBB2.CNV分析的HTS数据可以初步识别结直肠癌患者的ERBB2.增。

关键词：高通量测序(HTS) 数字PCR 免疫组织化学(IHC) 荧光原位杂交(FISH) 直肠癌

Wnt3a signaling promotes proliferation,myogenic differentiation,and migration of rat bone marrow mesenchymal stem cells

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Acta Pharmacologica Sinica 2007年第11期28卷 1761-1774页

作者： Yan-chang SHANG~(2.3),Shu-hui wang~4,Fu XIONG~5,Cui-ping ZHAO~2.Fu-ning {2.~2.Shan-wei FENG~2.Mei-shan li~2.Yongli~5,Cheng ZHANG~(2.5,6)~2.Department of Neurology First Affiliated Hospital,Sun Yat-sen university,Guangzhou 510080,china,~3 Department of Geriatric NeurologyChinese People's liberation Army General Hospital,Beijing 100853,china ~4 Department of Neurology,Beijing Friendship Hospital,CapitalMedical university,Beijing 100050,china,~5 Center for Stem Cell Biology and Tissue Engineering,Sun Yat-sen university Guangzhou510080.china ment of Neurology First Affiliated Hospital Sun Yat-sen University Guangzhou 510080China. zhangch6@***.

Aim:To investigate the effects of the wingless-related MMTV integration site 3A(Wnt3a) signaling on the proliferation,migration,and the myogenic and adipogenicdifferentiation of rat bone marrow mesenchymal stem cells (rMSC).Methods:Primary MSC were isolated and cultured from Sprague-Dawley rats and character-ized by flow *** L cells were transfected with Wnt3a cDNA,andconditioned media contai{2. active Wnt3a proteins were *** prolif-eration was evaluated by cell count and 5-bromodeoxyuridine incorporation *** migration of rMSC was performed by using a transwell migration and woundhealing *** myogenic and adipogenic differentiation in rMSC were exam-ined by light microscopy,immunofluorescence,and RT-PCR at different timepoints after myogenic or adipogenic ***:Wnt3a signaling in-duced β-catenin nuclear translocation and activated the Wnt pathway in *** the presence of Wnt3a,rMSC proliferated more rapidly than the control cells,keeping their differentiation ***,Wnt3a signaling induced 2.62.and 3.76% of rMSC-expressed desmin and myosin heavy chain after being cul-tured in myogenic *** myogenic differentiation genes,including Pax7,MyoD,Myf5,Myf4,and myogenin,were activated after Wnt3a *** theother hand,Wnt3a inhibited the adipogenic differentiation in rMSC through thedownregulated expression of CCAAT/enhancer-binding protein alpha (C/EBPalpha)and peroxisome proliferator-activated receptor gamma (PPARgamma).Furthermore,Wnt3a promoted the migration capacity of ***:The results indi-cate that Wnt3a signaling can induce myogenic differentiation in ***3asignaling is also involved in the regulation of the proliferation and migration *** results could provide a rational foundation for cell-based tissuerepair in humans.

关键词： Wingless-related MMTV integration site (Wnt) mesenchymal stem cells myogenic differentiation adipogenic differentiation proliferation migration

Spatial resolution and image processing for pinhole camera-based X-ray fluorescence imaging: a simulation study

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Nuclear Science and Techniques 2022年第5期33卷 135-153页

作者： Ze He ning Huang peng {2. Zi-Han Chen Bo peng Key Laboratory of Radiation Physics and Technology of the Ministry of Education Institute of Nuclear Science and TechnologySichuan UniversityChengdu 610064China

Spatial resolution and image-processing methods for full-field X-ray fluorescence(FF-XRF)imaging using X-ray pinhole cameras were studied using Geant4simulations with different geometries and algorithms for image *** main objectives were:(1)calculating the quantum efficiency curves of specific cameras,(2.studying the relationships between the spatial resolution and the pinhole diameter,magnification,and camera binning value,and(3)comparing image-processing methods for pinhole camera *** results were obtained using a point and plane source as the X-ray fluorescence emitter and an array of 100×100 silicon pixel detectors as the X-ray *** quantum efficiency of a back-illuminated deep depletion(BI-DD)structure was above 30%for the XRF energies in the 0.8–9 keV range,with the maximum of 93.7%at 4 *** best spatial resolution of the pinhole camera was 2..7μm and 31.3 lp/mm when measured using the profile function of the point source,with the diameter of 2.μm,magnification of 3.16,and camera bin of 1.A blind deconvolution algorithm with Gaussian filtering performed better than the Wiener filter and Richardson iterative methods on FF-XRF images,with the signal-to-noise ratio of 7.81 dB and improved signalto-noise ratio of 7.2. dB at the diameter of 12.μm,magnification of 1.0,and camera bin of 1.

关键词： Full-field X-ray fluorescence(FF-XRF) X-ray pinhole camera Spatial resolution Image processing

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政策工具视角下地方性学前教育法规研究

黑龙江教师发展学院学报 2024年第9期43卷 140-145页

作者：王鹏宁杨晓萍西南大学教育学部重庆400715

推进学前教育高质量发展是目前学前教育事业的重点之一,而高质量发展离不开法规的支持。以地方现行有效的2.部法规为研究对象,通过对政策工具与政策内容的交叉分析发现,目前法规内容可操作性不强、政策工具尚可优化、法规内容同质化明... 详细信息

推进学前教育高质量发展是目前学前教育事业的重点之一,而高质量发展离不开法规的支持。以地方现行有效的2.部法规为研究对象,通过对政策工具与政策内容的交叉分析发现,目前法规内容可操作性不强、政策工具尚可优化、法规内容同质化明显。因此,要细化法规内容,增强可操作性;增强政策工具的多元性和灵活性;突出法规的特色性,避免同质化。

关键词：学前教育地方性法规政策工具

Low dose of hydroxychloroquine reduces fatality of critically ill patients with COVID-19

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Science china(life {2.) 2020年第10期63卷 1515-1521页

作者： Bo Yu Chenze li peng Chen {2. Zhou Luyun wang Jia li Hualiang Jiang Dao-Wen wang Division of Cardiology Department of Internal Medicine and Hubei Key Laboratory of Genetics and Molecular Mechanisms of Cardiological DisordersTongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China State Key Laboratory of Drug Research Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Shanghai Institute for Advanced Immunochemical Studies and school of life Science and Technology Shanghai Tech UniversityShanghai 201210China

Coronavirus disease 2.19(COVID-19)is a pandemic with no specific drugs and high *** most urgent need is to find effective *** sought to determine whether hydroxychloroquine(HCQ)application may reduce the death risk of critically ill COVID-19 *** this retrospective study,we included 550 critically ill COVID-19 patients who need mechanical ventilation in Tongji Hospital,Wuhan,from February 1,2.2. to April 4,*** 550 patients received comparable basic treatments including antiviral drugs and antibiotics,and 48 of them were treated with oral HCQ treatment(2.0 mg twice a day for 7–10 days)in addition to the basic *** endpoint is fatality of patients,and inflammatory cytokine levels were compared between HCQ and non-hydroxychloroquine(NHCQ)*** found that fatalities are 18.8%(9/48)in HCQ group,which is significantly lower than 47.4%(2.8/502.in the NHCQ group(P2.)days and 8(4–14)days for the HCQ and NHCQ groups,respectively(P2..2.8.3–118.9)pg mL–1 at the beginning of the treatment to 5.2.3.0–2..4)pg mL–1(Plity of critically ill patients of COVID-19 through attenuation of inflammatory cytokine ***,HCQ should be prescribed as a part of treatment for critically ill COVID-19 patients,with possible outcome of saving lives.

关键词： patients drugs critically

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In-situ embedding CoTe catalyst into 1D-2. nitrogen-doped carbon to didirectionally regulate lithium-sulfur batteries

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Nano Research 2022年第10期15卷 8972-8982页

作者： Bin li peng {2. Baojuan Xi ning Song Xuguang An Weihua Chen Jinkui Feng Shenglin Xiong Key Laboratory of Colloid and Interface Chemistry Ministry of EducationSchool of Chemistry and Chemical EngineeringState Key Laboratory of Crystal MaterialsShandong UniversityJinan 250100China Key Laboratory of Mechanical Engineering of Education School of Mechanical EngineeringChengdu UniversityChengdu 610106China Key Laboratory of Material Processing and Mold of Ministry of Education Zhengzhou UniversityZhengzhou 450001China school of Materials Science and Engineering Shandong UniversityJinan 250061China

lithium-sulfur(li-S)batteries have been widely investigated attributed to their advantages of high energy density and cost ***,it is still limited by the uncontrolled shuttle effect of the sulfur cathode and the promiscuous dendrite growth over the lithium *** handle the above issues,the highly conductive CoTe catalyst is precisely loaded onto nitrogendoped nanotube and graphene-like carbon(CoTe NCGs),which is employed as a bi-functionally integrated *** the lithium anode,the CoTe NCGs with excellent lithiophilic property effectively regulate the uniform deposition of lithium and achieve the effect of suppressing the disorderly growth of lithium *** the sulfur cathode,the electrochemical conversion of lithium polysulfides(liPSs)is catalyzed to mitigate the notorious shuttle *** view of the bifunctionality of CoTe NCGs,the assembled full cell can be steadily stable even for 800 cycles at a high rate of 2.C,and the capacity decay rate is only 0.05%per *** areal capacity of 6.0 mAh·cm^(−2. is well retained after 50 cycles under the conditions of high sulfur loading,poor electrolyte(a low electrolyte-to-sulfur ratio,E/S=4.2.,and low negative to positive capacity ratio(N/P=1.6:1).

关键词： CoTe nanocrystals dual-functional shuttling effect lithium dendrite li-S batteries

补光光源和日累积光照量对草地早熟禾草坪质量的影响

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草地学报 2024年第7期32卷 2254-2262页

作者：谢昊鹏王宁刘进玮张敏王森陈佳宝张浩男李富翠王磊韩烈保北京林业大学草坪研究所北京100083 华体体育发展股份有限公司北京102101 北京华体创研工程设计咨询有限公司北京102400 北京建工集团有限责任公司北京100055

为降低体育场遮荫环境对草坪草生长的制约,提高运动场草坪的质量与性能,本研究以不补光为对照(CK),选用发光二极管(LED)和高压钠灯(HPS)作为补光光源,分别在11.18,15.12.18.36 mol·(m^(2.·d)^(-1)的日累积光照量(Daily light integra... 详细信息

为降低体育场遮荫环境对草坪草生长的制约,提高运动场草坪的质量与性能,本研究以不补光为对照(CK),选用发光二极管(LED)和高压钠灯(HPS)作为补光光源,分别在11.18,15.12.18.36 mol·(m^(2.·d)^(-1)的日累积光照量(Daily light integral,Dli)下培育草地早熟禾(Poa pratensis)草坪56天,探讨了补光对草坪温湿度、草坪质量、生物量、根系生长和叶绿素含量的影响。结果表明:HPS补光对草坪冠层增温效果高于LED,同时HPS补光降低了冠层湿度。LED和HPS补光灯均能维持草地早熟禾的草坪质量,增加Dli有利于草地早熟禾的生物量累积和根系生长,在Dli为18.36 mol·(m^(2.·d)^(-1)的处理下效果最佳。在LED补光18.36 mol·(m^(2.·d)^(-1)下生长的草地早熟禾的叶绿素a和叶绿素b含量显著高于HPS补光(Pli为18.36 mol·(m^(2.·d)^(-1)进行草地早熟禾草坪的补光养护,在夏季或气温较高的时候推荐使用LED补光。

关键词： LED 高压钠灯日累积光照量草地早熟禾草坪质量叶绿素含量