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Science china chemistry 2009年第8期52卷 1216-1219页

作者： wang naixing1,2 & tang xinliang1,3 1 technical institute of physics and chemistry,chinese academy of sciences,beijing 100080,china 2 College of chemistry and Chemical Engineering,Graduate University of chinese academy of sciences,beijing 100049,china 3 School of Chemical Engineering and Environment,beijing institute of Technology,beijing 100081,china technical institute of physics and chemistry Chinese Academy of Sciences Beijing China College of chemistry and Chemical Engineering Graduate University of Chinese Academy of Sciences Beijing China School of Chemical Engineering and Environment Beijing Institute of Technology Beijing China

R-Enantiomer of the β-receptor antagonist N-[3-acetyl-4-(2-hydroxy-3-isopropylamino-propoxy)phenyl] butanamide with high enantioselectivity was synthesized from cheap starting materials and enantiopure chiral reagent through an efficient,convenient and practical synthetic *** product was detected by 1H NMR,13C NMR,and MS,and the enatiomeric excess was determined by chiral HPLC analysis using a chiracel AD-H column.

关键词： chiral synthesis enantioselectivity enatiomeric excess chiral HPLC analysis

Correlation of Behavior Changes and BOLD Signal in Alzheimer-like Rat Model

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Acta Biochimica et Biophysica Sinica 2004年第12期36卷 803-810页

作者： Zheng-Hui HU#, Xiao-Chuan wang1#, Li-Yun LI3, Mai-Li LIU3, Rong LIU1, Zhiqun LING1, Qing TIAN1, Xiao-Wei tang, Yi-Gen WU2*, and Jian-Zhi wang1* Department of physics and Bio-X disciplinary Laboratory, Zhejiang University, Hangzhou 310027,china 1 Department of Pathophysiology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, china 2institute of High Energy physics and Key Laboratory of Nuclear Analysis Techniques, chinese academy of sciences, P.O. Box 918, beijing 100039, china 3Wuhan institute of physics and Mathematics, State Key Laboratory of Magnetic Resonance and Atomic and Molecular physics, chinese academy of sciences, Wuhan 430071, china Department of physics and Bio-X disciplinary Laboratory Zhejiang UniversityHangzhou 310027China Department of Pathophysiology Tongji Medical College Huazhong University of Science and TechnologyWuhan 430030 China Wuhan institute of physics and Mathematics State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Chinese Academy of SciencesWuhan 430071 China institute of High Energy physics and Key Laboratory of Nuclear Analysis Techniques Chinese Academy of SciencesP.O. Box 918 Beijing 100039 China

To explore a potential means for the early diagnosis of Alzheimer disease, we studied the relationship of resting T2* signal and tau hyperphosphorylation/spatial memory deficit. The rat model with tau hyperphosphorylation and spatial memory deficit was established by bilateral hippocampi injection of isoproterenol (IP). Then, the correlative alteration between resting T2* signal and spatial memory retention was assessed with blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) study and Morris Water Maze test, and Western blot was employed to confirm tau hyperphosphorylation. The analysis showed following results. (1) Tau phosphorylation at Ser396/Ser404 and Ser199/Ser202 was signifi- cantly increased in IP-injected rats as detected by PHF-1 and tau-1, respectively. (2) An AD-like spatial memory retention disturbance was induced at 24 h after isoproterenol injection. (3) A sensitivity threshold of resting T2* signal intensity, which separated the IP-treated rats from vehicle control, was obtained by applying linear regression analysis, and an estimated sensitivity statistical threshold was at 32.62. These results suggest that resting T2* signal may serve as a noninvasive quantitative marker in predicting AD-like spatial memory deficits and tau hyperphosphorylation.

关键词： Alzheimer disease (AD) functional magnetic resonance imaging (fMRI) isoproterenol (IP) Morris Water Maze diagnosis

Study of proton resonances in ^(18)Ne via resonant elastic scattering of ^(17)F+p and its astrophysical implication

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Science china(physics,Mechanics & Astronomy) 2011年第S1期54卷 32-36页

作者： HE JianJun1, HU Jun1,2, XU ShiWei1, CHEN ZhiQiang1, ZHANG XueYing1, wang JianSong1, YU XiangQing1, ZHANG LiYong1,2, LI Long1,2, YANG YanYun1,2, MA Peng1,2, ZHANG XueHeng1, HU ZhengGuo1, GUO ZhongYan1, XU Xing1,2, YUAN XiaoHua1, LU Wan1,2, YU YuHong1, ZANG YongDong1,2, tang ShuWen1,2, YE RuiPing1,2, CHEN JinDa1,2, JIN ShiLun1,2, DU ChengMing1,2, wang ShiTao1,2, MA JunBing1,2, LIU LongXiang1,2, BAI Zhen1,2, LEI XiangGuo1, SUN ZhiYu1, ZHANG YuHu1, ZHOU XiaoHong1, XU HuShan1, SU Jun3, LI ErTao3, wang HongWei4, TIAN WenDong4 & LI XiangQing5 1 institute of Modern physics (IMP), chinese academy of sciences, Lanzhou 730000, china 2 Graduate University of chinese academy of sciences, beijing 100049, china 3 china institute of Atomic Energy (CIAE), beijing 102413, china 4 Shanghai institute of Applied physics (SINAP), chinese academy of sciences, Shanghai 201800, china 5 School of physics and State Key Laboratory of Nuclear physics and Technology, Peking University, beijing 100871, china institute of Modern physics (IMP) Chinese Academy of Sciences Lanzhou China Graduate University of chinese academy of sciences Beijing China china institute of Atomic Energy (CIAE) Beijing China Shanghai institute of Applied physics (SINAP) Chinese Academy of Sciences Shanghai China School of physics and State Key Laboratory of Nuclear physics and Technology Peking University Beijing China

The proton resonant properties in 18Ne, which determine the reaction rate of the key stellar 14O(α,p)17F reaction, have been studied by using a technique of proton resonant elastic scattering of 17F+p. A 4.22 MeV/nucleon 17F radioactive ion (RI) beam was produced via a projectile-fragmentation reaction, and separated by a Radioactive Ion Beam Line in Lanzhou (RIBLL). By bombarding a thick (CH2)n target, the energy spectra of the recoiled protons were measured by two ΔE-E silicon telescopes at the center-of-mass scattering angles of θc.m.≈175°±5°, θc.m.≈152°±8°, respectively. Several proton resonances in 18Ne were ob served clearly. A further R-matrix analysis of the experimental data is under way to determine the resonant parameters. The present work reports the preliminary results briefly.

关键词： resonant reaction reaction rate explosive burning accreting binary systems

A template of rat brain based on fMRI T2* imaging

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Progress in Natural Science:Materials International 2005年第6期15卷 502-506页

作者： HU Zhenghui1, WU Yigen2, wang Xiaochuan3, wang Jianzhi3, CHEN Feiyan1 and tang Xiaowei1*(1. Department of physics and Bio-X Laboratory, Zhejiang University, Hangzhou 310027, china 2. institute of High Energy physics and Key Laboratory of Nuclear Analysis Techniques, chinese academy of sciences,beijing 100039, china 3. Department of Pathophysiology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, china) Department of physics and Bio-X Laboratory Zhejiang University Hangzhou 310027 China Key Laboratory of Nuclear Analysis Techniques Institute of High Energy Physics Chinese Academy of Sciences Beijing 100039 China Department of Pathophysiology Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 China

The development of functional magnetic resonance imaging (fMRI) technology has made it possible to carry out functional brain imaging experiments in small animals. Usually, group data is required to form the assessment of population, which can not only increase the sensitivity of the overall experiment, but also allow the generalization of the conclusion to the whole population. In order to average the signals of functional brain images from different subjects, it is necessary to put all the mapping images into the same standard space (template image). However, up to now, most animal brain templates remain unavailable and it must be done by ourselves. In this study, a template image based on the brains of eight male Wistar rats is obtained, and it is successfully used in our present Alzheimer disease (AD)-like rat model studies as template for spatially normalizing images to the same stereotaxical space. The fMRI results processed with statistical parametric mapping (SPM99) software are in agreement with the results from immunohistochemical experiment, which proves that this method is universally applicable to the pathologic models of other small animals and to human brain lesion studies.

关键词： fMRI animal model atlas template normalization T*2.

Environment-adaptive phase-separation-porous fluorofilm for highperformance passive radiation cooling

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Nano Research 2024年第6期17卷 5636-5644页

作者： Weiming tang Yong Li Xue Meng Shutao wang Ziguang Zhao School of Future Technology University of Chinese Academy of SciencesBeijing 100049China CAS Key Laboratory of Bio-inspired Materials and Interfacial Science Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China CAS Key Laboratory of Cryogenics Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China

Passive radiative cooling is widely recognized as an environmentally sustainable method for achieving significant cooling ***,the mechanical properties and environmental adaptability of current radiative cooling materials are not sufficient to maintain high cooling performance in external *** we reported an environment-adaptive phase-separation-porous fluorofilm for high-performance passive radiation *** to the homogenous fluoro-porous network with limited scattering efficiencies,we modulated the porous structure of the fluorofilm to achieve a strong emissivity of 95.2%(8-13μm)and a high reflectivity of 97.1%(0.3-2.5μm).The fluorofilm demonstrates a temperature drop of 10.5°C and an average cooling power of 81 W·m^(−2)under a sunlight power of 770 W·m^(−2).The high mechanical performance and environmental adaptability of fluorofilms are also *** its significant radiative cooling capability and robust environmental adaptability,the fluorofilm is expected to have a promising future in radiative temperature regulation.

关键词： fluorofilm passive radiation cooling porous optimization thermal regulation

STRUCTURE AND MAGNETIC PROPERTIES OF YFe_(12-x)Ti_x COMPOUNDS

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Acta Metallurgica Sinica(English Letters) 2001年第3期14卷 171-176页

作者： B. Fuquan, J.L. wang, N. tang, W.Q. wang, Z.Z. Guo, G.H. Wu and F.M. Yang (State Key Laboratory of Magnetism, institute of physics, The chinese academy of sciences, beijing 100080, china) (Department of physics, Inner Mongolia Normal University, Huhhot 01 State Key Lab. of Magnetism Inst. of Phys. Chinese Acad. of Sci. Beijing 100080 China

The structure and magnetic properties of the YFe12-xTix compounds (x=0.85, 1.00, 1.10, 1.20 and 1.30) have been investigated. Both the thermomagnetic analysis and X-ray diffraction patterns show that all compounds studied are almost single phase and crystallize in the ThMn12-type structure. The lattice parameters a, c and unit cell volume V increase monotonously with the increase of Ti content. Curie temperature Tc is almost independent on the Ti content while the spontaneous magnetization M0, the anisotropy field Ba and the anisotropy constant K1 decrease monotonously with the increase of Ti content and the temperature increases from 1.5 K to 293 K.

关键词： Iron Magnetic properties Structure (composition) Titanium Yttrium

A draft sequence of the rice (Oryza sativa ssp. indica) genome

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chinese Science Bulletin 2001年第23期46卷 1937-1942页

作者： YU Jun, HU Songnian, wang Jun,LI Songgang WONG Ka-Shu Gane, LIU Bin,DENG Yajun, DAI Li, ZHOU Yan,ZHANG Xiuqing, CAO Mengliang, LIU Jing,SUN Jiandong , tang Jiabin, CHEN Yanjiong,HUANG Xiaobing, LIN Wei, YE Chen, TONG Wei,CONG Lijuan, GENG Jianing, HAN Yujun, LI Lin,LI Wei, HU Guangqiang, HUANG Xiangang,LI Wenjie, LI Jian, LIU Zhanwei, LI Long,LIU Jianping, Ql Qiuhui, LIU Jinsong, LI Li,wang Xuegang, LU Hong, WU Tingling,ZHU Miao, Nl Peixiang, HAN Hua, DONG Wei,REN Xiaoyu, FENG Xiaoli, GUI Peng,LI Xianran, wang Hao, XU Xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, HE Sijie,ZHANG Jianguo, XU Jichen, ZHANG Kunlin,ZHENG Xianwu, DONG Jianhai, ZENG Wanyong,TAO Lin, CHEN Xuewei, HE Jun, LIU Daofeng,TIAN Wei, TIAN Chaoguang, XIA Hongai,LI Gang, GAO Hui, LI Ping, CHEN Wei ,wang Xudong, ZHANG Yong, HU Jianfei,wang Jing, LIU Song, YANG Jian,ZHANG Guangyu, XIONG Yuqing, LI Zhijie,MAO Long, ZHOU Chengshu, ZHU Zhen,CHEN Runsheng, HAO Bailin,ZHENG Weimou, CHEN Shouyi, QUO Wei,LI Guojie, LIU Siqi, HUANG Guyang,TAO Ming, wang Jian, ZHU Lihuang,YUAN Longping& YANG Huanmingbeijing Genomics institute/Center of Genomics & Bioinformatics, chinese academy of sciences, beijing 101300, china Hangzhou Genomics institute/institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, china institute of Genetics, chinese academy of sciences, beijing 100101, china National Hybrid Rice R & D Center, Changsha 410125, china Laboratory of Bioinformatics, institute of Biophysics, chinese academy of sciences, beijing 100101, china College of Life sciences, Peking University, beijing 100871, china institute of Theoretical physics, chinese academy of sciences, beijing 1Q0080, china Digital china Ltd., beijing 100080, china institute of Computing Technology, chinese academy of sciences, beijing 100080, china Medical College, Xi’an Jiaotong University, Xi’an 710061, chinaThese authors contributed equally to this work.Corresponding author.Corresponden beijing Genomics institute/Center of Genomics & Bioinformatics Chinese Academy of Sciences Beijing China Hangzhou Genomics institute/institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province Hangzhou China College of Life sciences Peking University Beijing China Medical College Xi’an Jiaotong University Xi’an China institute of Genetics Chinese Academy of Sciences Beijing China Laboratory of Bioinformatics Institute of Biophysics Chinese Academy of Sciences Beijing China National Hybrid Rice R & D Center Changsha China institute of Theoretical physics Chinese Academy of Sciences Beijing China Digital china Ltd. Beijing China institute of Computing Technology Chinese Academy of Sciences Beijing China

The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a "whole genome shotgun" approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in china and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2214.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.29% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLER, a custom-designed software package

关键词： rice genome draft sequences.

Knockout reaction mechanism studied by ~6He projectile

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Science china(physics,Mechanics & Astronomy) 2011年第S1期54卷 136-140页

作者： Lü LinHui1, YE YanLin1, JIANG DongXing1, HUA Hui1, ZHENG Tao1, LI ZhiHuan1, GE YuCheng1, LI XiangQing1, LOU JianLing1, CAO ZhongXin1, SONG YuShou1, XIAO Jun1, LI QiTe1, QIAO Rui1, YOU HaiBo1, CHEN RuiJiu1, XU HuShan2, wang JianSong2, GUO ZhongYan2, ZHANG XueYing2, LI Chen2, HU ZhengGuo2, CHEN RuoFu2, wang Meng2, XU ZhiGuo2, YUE Ke2, tang Bin2, ZANG YongDong2, ZHANG XueHeng2, YAO XiangWu2, CHEN JinDa2 & BAI Zhen2 1 School of physics and State Key Laboratory of Nuclear physics and Technology, Peking University, beijing 100871, china 2 institute of Modern physics, chinese academy of sciences, Lanzhou 730000, china School of physics and State Key Laboratory of Nuclear physics and Technology Peking University Beijing China institute of Modern physics Chinese Academy of Sciences Lanzhou China

Knockout reaction experiment was carried out by using the 6He beams at 61.2 MeV/u impinging on a CH2 target. The α core fragments at forward angles were detected in coincidence with the recoiled protons at larger angles. From this exclusive meas urement the valence nucleon knockout mechanism and the core knockout mechanism can be distinguished by the relation be tween the polar angles of the core fragments and the recoiled protons, respectively. It is demonstrated that the core knockout mechanism may result in some strong contamination to the real invariant mass spectrum.

关键词： exotic nuclei knockout reaction reaction mechanism invariant mass spectra

Interface optimization of graphene paper-Cu composite prepared by electrodeposition

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Journal of Iron and Steel Research International 2024年第1期31卷 64-73页

作者： Jing Guo Hai-jing wang Shuang-juan Liu Peng Zhang Jing-yu tang Wei-yang Zhang Han-jie Guo Peng-cheng wang Cai Meng School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing100083China institute of High Energy physics Chinese Academy of SciencesBeijing100049China Advanced Technology and Materials Co. Ltd.Beijing100083China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei230027AnhuiChina

A room-temperature electrodeposition method with an organic electrolyte was developed to fabricate a HNO3-pretreated graphene paper Cu(GP'-Cu)*** improve the interfacial bonding of GP'-Cu composite,magnetron sputtering technology was used to create a"sandwich"structural gradient GP'-Cu *** selection of the intermediate transition layer metal was based on two-dimensional *** electron microscopy,X-ray photoelectron spectroscopy,and other analytical methods confirmed that the addition of an intermediate transition metal(Cr,Ni)layer reduced the gap distance and enhanced the interfacial bonding of the GP'and Cu deposited *** GP'-Ni-Cu composite exhibited the largest increase in tensile strength and *** addition,it had the highest thermal diffusivity and elongation at break among the GP'-Cu,GP'-Cr-Cu and GP'-Ni-Cu composites.

关键词： Graphene paper Two-dimensional disregistry Magnetron sputtering Metal composite

Synthesis and characterization of a three-ring bent-core compound

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Science Bulletin 2005年第17期 35-39页

作者： tang Yanhong1, MEI Chongyu1, LI Shaojun2, wang Yan1, wang Xingdong1, wang Lixiang1, YAN Donghang1 & YE Cheng2 1. State Key Laboratory of Polymer physics and chemistry, Changchun institute of Applied chemistry, chinese academy of sciences, Changchun 130022, china 2. Center for Molecular Science, Laboratory of Organic Solid, institute of chemistry, chinese academy of sciences, beijing 100080, china

To investigate the vacuum-deposited films of the banana-shaped mesogens, we prepared a three-ring bent-core (that is, banana-shaped) compound m-bis(4-p- octoxysryrenyl)benzene (m-OSB) and used it as a prototype for studying the related film physics. Herein the synthesis and the structural characterization of m-OSB are reported. 13C and 1H NMR spectra and IR spectrum confirm that m-OSB has a symmetric and all-trans conformation. The results of differential scanning calorimetry, polarizing optical microscopy and X-ray diffractometry indicate that no liquid crystalline phase but two crystalline phases are present in this material: phase I (T<66℃) and phase II (66℃更多还原AbstractFilter('ChDivSummary', 'ChDivSummaryMore', 'ChDivSummaryReset');

关键词： banana-shaped mesogens bent-core molecules anti-ferro-electric alignment.