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Efficacy of electroacupuncture on myocardial protection and postoperative rehabilitation in patients undergoing cardiac surgery with cardiopulmonary bypass:a systematic review and Meta-analysis

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Journal of Traditional Chinese Medicine 2024年第1期44卷 1-15页

作者： QIN Xiaoyu wang Chunai XUE Jianjun ZHANG Jie LU Xiaoting DING Shengshuang GE Long wang minzhen the First Clinical Medical College Gansu University of Chinese MedicineLanzhou 730030China Department of Anesthesiology Gansu Provincial Hospital of Traditional Chinese MedicineLanzhou 730050China Evidence-based Medicine Center Lanzhou UniversityLanzhou 730030China Institute of Epidemiology and Statistics School of Public HealthLanzhou UniversityLanzhou 730030China

OBJECTIVE:To evaluate the efficacy of electroacupuncture(EA)intervention on myocardial protection and postoperative rehabilitation in patients undergoing cardiac surgery with cardiopulmonary bypass(CPB).METHODS:Eight databases,including Pub Med,Embase,the Cochrane Library,Web of Science,Chinese Bio Medical Literature Database,China National Knowledge Infrastructure Database,Wanfang Data,China Science and Technology Journal Database,and two clinical trial registries,were *** randomized controlled trials(RCTs)related to EA intervention in cardiac surgery with CPB were *** on the inclusion and exclusion criteria,two researchers independently screened articles and extracted *** the quality evaluation,RevMan 5.3 software was used for ***:Fourteen RCTs involving 836 patients were *** with the control treatment,EA significantly increased the incidence of cardiac automatic rebeat after aortic unclamping[relative risk(RR)=1.15,95%confidence interval(CI)(1.01,1.31),P<0.05;moderate].Twenty-four hours after aortic unclamping,EA significantly increased the superoxide dismutase[standardized mean difference(SMD)=0.96,95%CI(0.32,1.61),P<0.05;low],and interleukin(IL)-2[SMD=1.33,95%CI(0.19,2.47),P<0.05;very low]expression levels and decreased the malondialdehyde[SMD=-1.62,95%CI(-2.15,-1.09),P<0.05;moderate],tumour necrosis factor-α[SMD=-1.28,95%CI(-2.37,-0.19),P<0.05;moderate],and cardiac troponin I[SMD=-1.09,95%CI(-1.85,-0.32),P<0.05;low]expression levels as well as the inotrope scores[SMD=-0.77,95%CI(-1.22,-0.31),P<0.05;high].There was no difference in IL-6 and IL-10 expression *** amount of intraoperative sedative[SMD=-0.31,95%CI(-0.54,-0.09),P<0.05;moderate]and opioid analgesic[SMD=-0.96,95%CI(-1.53,-0.38),P<0.05;low]medication was significantly lower in the EA group than in the control ***,the postoperative tracheal intubation time[SMD=-0.92,95%CI(-1.40,-0.45),P<0.05;low]and intensive care unit stay[SMD=-1.

关键词： electroacupuncture cardiopulmonary bypass thoracic surgery myocardial ischaemia-reperfusion injury myocardial protection postoperative rehabilitation Meta-analysis randomized controlled trial

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Research on Transmission Line Tower Tilting and Foundation State Monitoring Technology Based onMulti-Sensor Cooperative Detection and Correction

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Energy Engineering 2024年第1期121卷 169-185页

作者： Guangxin Zhang Minghui Liu Shichao Cheng minzhen wang Changshun Zhao Hongdan Zhao Gaiming Zhong College of Science and Technology(CST) Ningbo UniversityNingbo315000China Dadong Power Supply Company State Grid Liaoning Electric Power Co.Ltd.Dandong118000China Dalian Power Supply Company State Grid Liaoning Electric Power Co.Ltd.Dalian116000China Yanbian Power Supply Company State Grid Jilin Electric Power Co.Ltd.Yanji133000China Liaoyuan Power Supply Company State Grid Jilin Electric Power Co.Ltd.Liaoyuan136200China

The transmission line tower will be affected by bad weather and artificial subsidence caused by the foundation and other factors in the power *** tower’s tilt and severe deformation will cause the building to *** small changes caused the tower’s collapse,but the early staff often could not intuitively notice the changes in the tower’s *** the current tower online monitoring system,terminal equipment often needs to replace batteries frequently due to premature exhaustion of *** to the need for real-time measurement of power line tower,this research designed a real-time monitoring device monitoring the transmission tower attitude tilting and foundation state based on the inertial sensor,the acceleration of 3 axis inertial sensor and angular velocity raw data to pole average filtering pre-processing,and then through the complementary filtering algorithm for comprehensive calculation of tilt angle,the system meets the demand for inclined online monitoring of power line poles and towers regarding measurement accuracy,with low cost and power *** optimization multi-sensor cooperative detection and correction measured tilt angle result relative accuracy can reach 1.03%,which has specific promotion and application value since the system has the advantages of unattended and efficient calculation.

关键词： Transmission line tower tilting multi-sensor foundation state monitoring collaborative detection

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Predictive value of total cholesterol to high-density lipoprotein cholesterol ratio for chronic kidney disease among adult male and female in Northwest China

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Chronic Diseases and Translational Medicine 2024年第3期10卷 216-226页

作者： Yanli Liu Kang Lyu Shaodong Liu Jinlong You Xue wang minzhen wang Desheng Zhang Yana Bai Chun Yin Min Jiang Shan Zheng School of Public Health Institute of Epidemiology and StatisticsLanzhou UniversityLanzhouGansuChina Workers'Hospital of Jinchuan Group Co.Ltd. JinchangGansuChina Wuwei People's Hospital WuweiGansuChina

Background: Studies have found that the ratio of total cholesterol to high-density lipoprotein cholesterol (TC/HDL-C) was associated with the development of chronic kidney disease (CKD). However, the relationship in different genders was rarely discussed. The aim of this study was to explore this relationship and assess its predictive power for both males and ***: Based on a prospective cohort platform in northwest China, 32,351 participants without CKD were collected in the baseline and followed up for approximately 5 years. Cox proportional hazard model and restricted cubic spline regression analysis were performed to investigate the association between TC, HDL-C, TC/HDL-C and CKD in adult female and male. The clinical application value of the indicators in predicting CKD was evaluated by the receiver operator characteristic ***: During a mean follow-up of 2.2 years, 484 males and 164 females developed CKD. After adjusted for relevant confounders, for every one standard deviation increase in TC, HDL-C and TC/HDL-C, the hazard ratios (HRs) and 95% confidence intervals (95% CIs) for CKD were 1.17 (1.05-1.31), 0.84 (0.71-0.99), and 1.15 (1.06-1.25) for males, 0.94 (0.78-1.13), 0.58 (0.35-0.95), and 1.19 (1.01-1.40) for females, respectively. The results also showed that TC, HDL-C, and TC/HDL-C were associated with CKD in a linear dose-response relationship. The TC/HDL-C had the largest area under the curve (AUC) compared to TC and HDL-C, and the AUC among the females was larger than that among ***: The TC/HDL-C was significantly associated with CKD in adult males and females and has better clinical value in predicting CKD than TC and HDL-C, especially in females.

关键词： chronic kidney disease gender Jinchang Cohort predictive value TC/HDL-C

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金昌队列职业人群颈动脉粥样硬化发病情况及其与脑卒中发病关联

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中国公共卫生 2024年第6期40卷 666-673页

作者：吕康张晓飞刘少东王雪罗妍王敏珍尹春白亚娜郑山兰州大学公共卫生学院流行病与卫生统计学系西安市雁塔区疾病预防控制中心金川集团有限公司职工医院心血管内科

目的了解金昌队列职业人群颈动脉粥样硬化(CAS)发病情况及其与脑卒中发病的关系，为CAS及脑卒中的防治提供科学依据。方法依托金昌队列平台抽取2011年6月—2013年12月完成基线调查并进行颈部彩色多普勒超声检查且信息完整的职业人群... 详细信息

目的了解金昌队列职业人群颈动脉粥样硬化(CAS)发病情况及其与脑卒中发病的关系，为CAS及脑卒中的防治提供科学依据。方法依托金昌队列平台抽取2011年6月—2013年12月完成基线调查并进行颈部彩色多普勒超声检查且信息完整的职业人群为研究对象，并分别匹配2015年和2017年完成的第1期及第2期随访信息，在排除不合格对象后最终纳入6 262名职业人群计算其CAS和脑卒中的累积发病率，应用多因素非条件logistic回归模型分析CAS、颈动脉内–中膜增厚和颈动脉硬化斑块发生的影响因素，并应用多因素Cox比例风险回归模型分析CAS、颈动脉内–中膜增厚和颈动脉硬化斑块者的脑卒中发病风险及发生脑卒中的影响因素。结果金昌队列职业人群第1期随访0.08～3.75年，平均随访(1.71±0.55)年；共发生CAS者1 147例，累积发病率为18.32%，其中发生颈动脉内–中膜增厚者和颈动脉硬化斑块者分别为287例和860例，累积发病率分别为4.58%和13.73%。多因素非条件logistic回归分析结果显示，年龄≥45岁、目前仍吸烟、高血压、糖尿病、总胆固醇(TC)异常、职业为干部或技术人员和内勤人员是金昌队列职业人群发生CAS的危险因素，大专及以上文化程度是金昌队列职业人群发生CAS的保护因素；年龄≥45岁、职业为干部或技术人员、目前仍吸烟、高糖饮食和高血压是金昌队列职业人群发生颈动脉内–中膜增厚的危险因素，女性是金昌队列职业人群发生颈动脉内–中膜增厚的保护因素；女性、年龄≥45岁、职业为内勤人员、高血压、糖尿病和TC异常是金昌队列职业人群发生颈动脉硬化斑块的危险因素，大专及以上文化程度是金昌队列职业人群发生颈动脉硬化斑块的保护因素。金昌队列职业人群第2期随访0.06～4.37年，平均随访(2.67±0.55)年；共发生脑卒中者240例，累积发病率为3.83%，其中CAS、颈动脉内–中膜增厚和颈动脉硬化斑块者的脑卒中发病数分别为104例、19例和85例，脑卒中累积发病率分别为9.07%、6.62%和9.88%；多因素Cox比例风险回归模型分析结果显示，在调整了性别、年龄、文化程度、职业、吸烟情况、饮酒情况、体育锻炼情况、是否高盐饮食、是否高脂饮食、是否高糖饮食、是否高血压、是否糖尿病、是否高尿酸血症、体质指数(BMI)、是否TC异常、是否高油三脂(TG)异常、是否高密度脂蛋白胆固醇(HDL-C)异常、是否低密度脂蛋白胆固醇(LDL-C)异常和是否肾小球滤过率下降等混杂因素后，金昌队列职业人群中CAS者脑卒中的发病风险为非CAS者的1.421倍(HR=1.421,95%CI=1.030～1.961)；年龄≥45岁、高盐饮食和超重是CAS者脑卒中发病的危险因素，女性和高尿酸血症是颈动脉内–中膜增厚者脑卒中发病的危险因素，文化程度高中或中专、高盐饮食和超重是颈动脉硬化斑块者脑卒中发病的危险因素。结论金昌队列职业人群CAS和脑卒中的累积发病率均较高，心血管疾病负担较重；CAS者的脑卒中发病风险较高，年龄较大、高盐饮食和超重是CAS者发生脑卒中的主要危险因素。

关键词：颈动脉粥样硬化(CAS) 脑卒中发病关系职业人群金昌队列

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Comparing the Diagnostic Criteria of MAFLD and NAFLD in the Chinese Population:A Population-based Prospective Cohort Study

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Journal of Clinical and Translational Hepatology 2022年第1期10卷 6-16页

作者： Cheng Yu minzhen wang Shan Zheng Miao Xia Hongyan Yang Desheng Zhang Chun Yin Ning Cheng Yana Bai Department of Epidemiology and Statistics School of Public HealthLanzhou UniversityLanzhouGansuChina Workers’Hospital of Jinchuan Group Co LtdJinchangGansuChina Centre of Medical Laboratory School of Basic Medical ScienceLanzhou UniversityLanzhouGansuChina

Background and Aims:Metabolic dysfunction-associ-ated fatty liver disease(MAFLD)is a new concept,pro-posed in 2020;however,its applicability in Asia populations has yet to be ***,we aimed to compare the difference in epidemiological and clinical characteris-tics between MAFLD and non-alcoholic fatty liver disease(NAFLD)among Asian ***:Based on the Jinchang cohort,30,633 participants were *** prevalence and incidence of MAFLD and NAFLD were used to analyze the epidemic characteristics and its overlapping *** addition,the corresponding clinical character-istics of the two diagnostic criteria populations were ***:The prevalence rates of MAFLD and NAFLD were 21.03%and 18.83%,*** an average 2.28-year follow-up,the incidence densities of MAFLD and NAFLD were 41.58 per 1,000 person-years and 37.69 per 1,000 person-years,*** the increase of baseline age,body mass index(BMI),and waist circumfer-ence(WC)levels,the prevalence and incidence of MAFLD and NAFLD were on the rise(all ptrend<0.05).Among the total patients diagnosed at baseline or follow-up,most pa-tients had both MAFLD and NAFLD,accounting for 78.84%and 82.88%,*** with NAFLD,MAFLD patients had greater proportions of males and metabolic diseases(diabetes,dyslipidemia),and had higher BMI,WC,liver enzymes,blood glucose,and lipid levels in the base-line diagnosis patients(p<0.05).Additionally,lean MAFLD patients had higher metabolic disorders than lean NAFLD patients(p<0.05).Conclusions:Compared with NAFLD,the newly proposed definition of MAFLD is more practical and accurate,and it can help identify more fatty liver pa-tients with high-risk diseases.

关键词： MAFLD NAFLD Diagnostic criteria Applicability Prospective cohort study.

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Astrocytic endothelin-1 overexpression impairs learning and memory ability in ischemic stroke via altered hippocampal neurogenesis and lipid metabolism

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Neural Regeneration Research 2024年第3期19卷 650-656页

作者： Jie Li Wen Jiang Yuefang Cai Zhenqiu Ning Yingying Zhou Chengyi wang Sookja Ki Chung Yan Huang Jingbo Sun minzhen Deng Lihua Zhou Xiao Cheng Guangzhou University of Traditional Chinese Medicine GuangzhouGuangdong ProvinceChina State Key Laboratory of Dampness Syndrome of Chinese Medicine The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhouGuangdong ProvinceChina Guangdong Provincial Key Laboratory of Research on Emergency in TCM GuangzhouGuangdong ProvinceChina Department of Anesthesiology West China HospitalSichuan UniversityChengduSichuan ProvinceChina Department of Anatomy Sun Yat-Sen School of MedicineSun Yat-Sen UniversityShenzhenGuangdong ProvinceChina Faculty of Medicine Macao University of Science and TechnologyMacao Special Administration RegionChina

Vascular etiology is the second most prevalent cause of cognitive impairment ***-1,which is produced and secreted by endothelial cells and astrocytes,is implicated in the pathogenesis of ***,the way in which changes in astrocytic endothelin-1 lead to poststroke cognitive deficits following transient middle cerebral artery occlusion is not well ***,using mice in which astrocytic endothelin-1 was overexpressed,we found that the selective overexpression of endothelin-1 by astrocytic cells led to ischemic stroke-related dementia(1 hour of ischemia;7 days,28 days,or 3 months of reperfusion).We also revealed that astrocytic endothelin-1 overexpression contributed to the role of neural stem cell proliferation but impaired neurogenesis in the dentate gyrus of the hippocampus after middle cerebral artery *** proteome profiles and western blot analysis confirmed that levels of glial fibrillary acidic protein and peroxiredoxin 6,which were differentially expressed in the brain,were significantly increased in mice with astrocytic endothelin-1 overexpression in comparison with wild-type mice 28 days after ischemic ***,the levels of the enriched differentially expressed proteins were closely related to lipid metabolism,as indicated by Kyoto Encyclopedia of Genes and Genomes pathway *** chromatography-mass spectrometry nontargeted metabolite profiling of brain tissues showed that astrocytic endothelin-1 overexpression altered lipid metabolism products such as glycerol phosphatidylcholine,sphingomyelin,and phosphatidic ***,this study demonstrates that astrocytic endothelin-1 overexpression can impair hippocampal neurogenesis and that it is correlated with lipid metabolism in poststroke cognitive dysfunction.

关键词： astrocytic endothelin-1 dentate gyrus differentially expressed proteins hippocampus ischemic stroke learning and memory deficits lipid metabolism neural stem cells neurogenesis proliferation

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Research on the Work-for-Relief Policy within the Scope of Comprehensive Rural Revitalization:Quantitative Analysis of Policy Texts Based on 71 Policy Documents

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Proceedings of Business and Economic Studies 2024年第3期7卷 212-219页

作者： Mengyuan Li minzhen Li Zhaoxian wang Yuyu Chen Jiaxin Di College of Humanities Tianjin Agricultural UniversityTianjin 300384China College of Economics and Management Tianjin Agricultural UniversityTianjin 300384China

Work-for-relief plays a unique role in China’s journey toward *** the perspectives of policy tools and interest analysis,this paper uses quantitative analysis of policy texts and integrates grounded theory to build a policy expression analysis model to discuss the current work-for-relief policy *** study found that China’s use of the work-for-relief policy is unbalanced,and it is necessary to enhance the involvement of non-governmental sectors,as well as to fully consider the policy’s target groups and the social issues that need addressing.

关键词： Work-for-relief Policy analysis Policy tools

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新型冠状病毒感染疫情期间高校学生睡眠现状及其与心理健康的双向关联研究

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世界睡眠医学杂志 2024年第1期11卷 226-230页

作者：汤静张静霞陈少锋蒋霞王敏珍孙伟伟甘肃中医药大学卫生管理学院兰州730000 西北民族大学附属医院(甘肃省第二人民医院)精神卫生中心儿童青少年心理科兰州730000 西北民族大学附属医院(甘肃省第二人民医院)精神卫生中心心理危机干预科兰州730000 兰州大学临床医学院流行病教研室兰州730000 西北民族大学附属医院(甘肃省第二人民医院)精神卫生中心心身疾病科兰州730000

目的:分析新型冠状病毒感染疫情期间高校学生睡眠、抑郁和焦虑情绪现状及其双向关联。方法:以在校高校学生为研究对象,采用线上问卷调查方法,共收集有效问卷1078份,使用匹兹堡睡眠质量指数量表(PSQI)、抑郁自评量表(SDS)、焦虑自评量表(... 详细信息

目的:分析新型冠状病毒感染疫情期间高校学生睡眠、抑郁和焦虑情绪现状及其双向关联。方法:以在校高校学生为研究对象,采用线上问卷调查方法,共收集有效问卷1078份,使用匹兹堡睡眠质量指数量表(PSQI)、抑郁自评量表(SDS)、焦虑自评量表(SAS)评估睡眠质量及抑郁和焦虑情绪,主要分析方法有t检验、χ^(2)检验、Logistics回归分析。结果:新型冠状病毒感染疫情期间本科院校学生的抑郁、焦虑情绪和睡眠较差的检出率分别为39.86%、23.13%和20.64%,高职(专科)院校学生分别为23.84%、50.83%和21.71%,本科院校与高职(专科)院校学生抑郁情绪检出率比较差异有统计学意义(P<0.05)。无论是本科院校还是高职(专科)院校,存在抑郁情绪的学生PSQI得分和睡眠较差的检出率均高于无抑郁情绪的学生(P<0.05);存在焦虑情绪的学生PSQI得分和睡眠较差的检出率均高于无焦虑情绪的学生(P<0.05)。Logistics回归分析显示,无论是本科院校还是高职(专科)院校的学生,睡眠较差是产生抑郁情绪(OR=4.798,95%CI为2.448~9.402、OR=3.768,95%CI为1.963~7.232)和焦虑情绪(OR=3.424,95%CI为2.324~5.046、OR=4.407,95%CI为3.006~6.459)的危险因素;存在抑郁情绪(OR=5.092,95%CI为2.640~9.822、OR=3.614,95%CI为2.435~5.363)和焦虑情绪(OR=4.692,95%CI为2.513~8.759、OR=4.397,95%CI为2.979~6.490)是出现睡眠较差的危险因素。结论:新型冠状病毒感染疫情期间大学生睡眠质量一般,抑郁和焦虑情绪检出率较高,睡眠与焦虑、抑郁情绪存在双向关联。高校应加强对学生的心理健康教育,需要更加关注睡眠质量较差的学生,必要时干预存在抑郁和焦虑情绪学生的睡眠。

关键词：新型冠状病毒感染疫情大学生睡眠焦虑抑郁双向关联

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人本位护理方式在高龄妊娠期高血压产妇中的临床效果

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中国医药指南 2022年第2期20卷 148-151页

作者：王敏珍营口市妇产儿童医院辽宁营口115000

目的探讨高龄妊娠期高血压产妇应用人本位护理方式的效果。方法回顾性选取2018年7月至2019年10月本院收治的高龄妊娠期产妇66例,采用时间分界将患者分为对照组(2018年7月至2019年2月)和试验组(2019年3—10月),每组33例。对照组实施常规... 详细信息

目的探讨高龄妊娠期高血压产妇应用人本位护理方式的效果。方法回顾性选取2018年7月至2019年10月本院收治的高龄妊娠期产妇66例,采用时间分界将患者分为对照组(2018年7月至2019年2月)和试验组(2019年3—10月),每组33例。对照组实施常规护理干预,试验组实施人本位护理干预,对比两组患者的心率、血压水平变化、负性情绪评分及护理满意度。结果干预前,试验组心率、舒张压、收缩压水平及SAS评分、SDS评分与对照组比较,差异无统计学意义(P>0.05);干预后,试验组患者心率、舒张压、收缩压水平显著低于对照组,差异有统计学意义(P<0.05);试验组SDS评分、SAS评分显著低于对照组,差异有统计学意义(P<0.05);试验组护理满意度显著高于对照组,差异有统计学意义(P<0.05)。结论在高龄妊娠期高血压产妇中应用人本位护理干预有助于使心率、血压控制在正常水平,缓解患者的负性情绪,提升产妇对护理服务工作的满意度,帮助其产后更好的恢复。

关键词：妊娠高血压高龄人本位护理

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前置胎盘期待疗法中应用阶段性目标护理的效果观察

引用

中国医药指南 2022年第9期20卷 50-53页

作者：王敏珍营口市妇产儿童医院辽宁营口115000

目的探讨阶段性目标护理应用在前置胎盘期待疗法中的效果。方法随机选取2018年9月至2019年9月本院收治前置胎盘患者94例进行回顾性分析,按照患者盲摸双色球法分组法,分为两组研究组和对照组,两组患者组内均为47例。对照组实施常规护... 详细信息

目的探讨阶段性目标护理应用在前置胎盘期待疗法中的效果。方法随机选取2018年9月至2019年9月本院收治前置胎盘患者94例进行回顾性分析,按照患者盲摸双色球法分组法,分为两组研究组和对照组,两组患者组内均为47例。对照组实施常规护理干预措施,研究组实施阶段性目标护理干预措施,将两组患者干预前后的焦虑(SAS)评分、抑郁(SDS)评分及对各项护理的依从性、干预前后生活质量的数据评分进行对比。结果研究得知,两组在护理干预以前SAS评分、SDS评分不具有统计学差异(P>0.05),护理干预后研究组SAS评分(49.56±1.06)分、SDS评分(51.25±2.57)分全部低于对照组SAS评分(54.12±1.13)分、SDS评分(56.84±2.92)分,统计学意义具有(P0.05);护理干预以后研究组生理功能、躯体疼痛、精力、情感职能、健康变化、一般健康状况、生理职能、社会功能评分均高于对照组,统计学意义具有(P<0.05)。结论将阶段性目标护理应用在前置胎盘期待疗法中改善患者焦虑、抑郁情绪,提高患者对干预的依从性,并且提高了生活质量,改善产妇的妊娠结局。

关键词：前置胎盘阶段性目标护理效果生活质量依从性

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