Efficacy of electroacupuncture on myocardial protection and postoperative rehabilitation in patients undergoing cardiac surgery with cardiopulmonary bypass:a systematic review and Meta-analysis

作     者：QIN Xiaoyu WANG Chunai XUE Jianjun ZHANG Jie LU Xiaoting DING Shengshuang GE Long WANG Minzhen QIN Xiaoyu;WANG Chunai;XUE Jianjun;ZHANG Jie;LU Xiaoting;DING Shengshuang;GE Long;WANG Minzhen

作者机构：the First Clinical Medical CollegeGansu University of Chinese MedicineLanzhou 730030China Department of AnesthesiologyGansu Provincial Hospital of Traditional Chinese MedicineLanzhou 730050China Evidence-based Medicine CenterLanzhou UniversityLanzhou 730030China Institute of Epidemiology and StatisticsSchool of Public HealthLanzhou UniversityLanzhou 730030China 

出 版 物：《Journal of Traditional Chinese Medicine》 (中医杂志（英文版）)

年 卷 期：2024年第44卷第1期

页      面：1-15页

核心收录：

学科分类：1005[医学-中医学] 1002[医学-临床医学] 100512[医学-针灸推拿学] 10[医学] 

基　　金：the National Natural Science Foundation of China:Mechanism of Protective Effect of Acupoint Preconditioning on Myocardial Mitochondria and Energy Metabolism in Rats with Bupivacaine Toxicity(No.81760892) 

主　　题：electroacupuncture cardiopulmonary bypass thoracic surgery myocardial ischaemia-reperfusion injury myocardial protection postoperative rehabilitation Meta-analysis randomized controlled trial 

摘      要：OBJECTIVE:To evaluate the efficacy of electroacupuncture(EA)intervention on myocardial protection and postoperative rehabilitation in patients undergoing cardiac surgery with cardiopulmonary bypass(CPB).METHODS:Eight databases,including Pub Med,Embase,the Cochrane Library,Web of Science,Chinese Bio Medical Literature Database,China National Knowledge Infrastructure Database,Wanfang Data,China Science and Technology Journal Database,and two clinical trial registries,were *** randomized controlled trials(RCTs)related to EA intervention in cardiac surgery with CPB were *** on the inclusion and exclusion criteria,two researchers independently screened articles and extracted *** the quality evaluation,RevMan 5.3 software was used for ***:Fourteen RCTs involving 836 patients were *** with the control treatment,EA significantly increased the incidence of cardiac automatic rebeat after aortic unclamping[relative risk(RR)=1.15,95%confidence interval(CI)(1.01,1.31),P0.05;moderate].Twenty-four hours after aortic unclamping,EA significantly increased the superoxide dismutase[standardized mean difference(SMD)=0.96,95%CI(0.32,1.61),P0.05;low],and interleukin(IL)-2[SMD=1.33,95%CI(0.19,2.47),P0.05;very low]expression levels and decreased the malondialdehyde[SMD=-1.62,95%CI(-2.15,-1.09),P0.05;moderate],tumour necrosis factor-α[SMD=-1.28,95%CI(-2.37,-0.19),P0.05;moderate],and cardiac troponin I[SMD=-1.09,95%CI(-1.85,-0.32),P0.05;low]expression levels as well as the inotrope scores[SMD=-0.77,95%CI(-1.22,-0.31),P0.05;high].There was no difference in IL-6 and IL-10 expression *** amount of intraoperative sedative[SMD=-0.31,95%CI(-0.54,-0.09),P0.05;moderate]and opioid analgesic[SMD=-0.96,95%CI(-1.53,-0.38),P0.05;low]medication was significantly lower in the EA group than in the control ***,the postoperative tracheal intubation time[SMD=-0.92,95%CI(-1.40,-0.45),P0.05;low]and intensive care unit stay[SMD=-1.