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散结膏外敷治疗肌肉注射后硬结20例

中医外治杂志 2008年第5期17卷 24-24页

作者：段沛涛董洪燕王富田山东省胶州市李哥庄中心卫生院山东胶州266316

目的:观察应用散结膏外敷治疗肌肉注射后硬结的临床疗效。方法:将肌肉注射后硬结患者60例随机分为三组,各20例,治疗组采用散结膏外敷治疗,对照组中A组采用热毛巾外敷,B组采用新鲜土豆切薄片贴于硬结治疗。1个疗程后观察临床效果。结果:... 详细信息

目的:观察应用散结膏外敷治疗肌肉注射后硬结的临床疗效。方法:将肌肉注射后硬结患者60例随机分为三组,各20例,治疗组采用散结膏外敷治疗,对照组中A组采用热毛巾外敷,B组采用新鲜土豆切薄片贴于硬结治疗。1个疗程后观察临床效果。结果:治疗组治愈率达100%,A组为10.00%,B组为55.00%。结论:采用散结膏外敷治疗肌肉注射后硬结有显著疗效。

关键词：肌肉注射后硬结散结膏外治法

Ionically Imprinting-Based Copper(Ⅱ)Label-Free Detection for Preventing Hearing Loss

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Engineering 2024年第2期33卷 276-282页

作者： Huan wang Hui Zhang Xiaoli Zhang Hong Chen Ling Lu Renjie Chai The Eighth Affiliated Hospital Sun Yat-Sen UniversityShenzhen 518033China State Key Laboratory of Digital Medical Engineering Department of Otolaryngology Head and Neck SurgeryZhongda Hospital&Advanced Institute for Life and HealthSoutheast UniversityNanjing 210096China Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging Department of Biomedical EngineeringShenzhen UniversityShenzhen 518060China Department of Otolaryngology Head and Neck Surgery Jiangsu Provincial Key Medical DisciplineNanjing Drum Tower HospitalThe Affiliated Hospital of Nanjing University Medical SchoolNanjing 210008China Co-Innovation Center of Neuroregeneration Nantong UniversityNantong 226001China Department of Otolaryngology Head and Neck Surgery Sichuan Provincial People's HospitalUniversity of Electronic Science and Technology of ChinaChengdu 610072China Institute for Stem Cell and Regeneration Chinese Academy of ScienceBeijing 100101China Beijing Key Laboratory of Neural Regeneration and Repair Capital Medical UniversityBeijing 100069China

Copper is a microelement with important physiological functions in the ***,the excess copper ion(Cu^(2+))may cause severe health problems,such as hair cell apoptosis and the resultant hearing ***,the assay of Cu^(2+)is *** integrate ionic imprinting technology(IIT)and structurally colored hydrogel beads to prepare chitosan-based ionically imprinted hydrogel beads(IIHBs)as a low-cost and high-specificity platform for Cu^(2+)*** IIHBs have a macroporous microstructure,uniform size,vivid structural color,and magnetic *** incubated in solution,IIHBs recognize Cu^(2+)and exhibit a reflective peak change,thereby achieving label-free *** addition,benefiting from the IIT,the IIHBs display good specificity and selectivity and have an imprinting factor of 19.14 at 100μmol·L^(-1).These features indicated that the developed IIHBs are promising candidates for Cu^(2+)detection,particularly for the prevention of hearing loss.

关键词： Structural color Microfluidics Ionic imprinting Label-free detection Hearing loss

城市内部创新空间集聚演化与环境要素对创新产出的影响——以深圳市为例

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经济地理 2024年第4期44卷 84-90页

作者：王波谢金燕王莉中山大学地理科学与规划学院广东广州510275 南方海洋科学与工程广东省实验室(珠海) 广东珠海519000 广东省城市化与地理环境空间模拟重点实验室广东广州510275 广州市城市规划勘测设计研究院广东广州510060

基于深圳市2005、2010、2015和2020年专利申请和兴趣点数据,从微观尺度上(1 km×1 km单元格)展示深圳市4个年份的创新空间演化特征,并通过对各年份的空间自回归泊松模型进一步考察了创新环境各要素对城市创新空间的影响及其变化。研究发... 详细信息

基于深圳市2005、2010、2015和2020年专利申请和兴趣点数据,从微观尺度上(1 km×1 km单元格)展示深圳市4个年份的创新空间演化特征,并通过对各年份的空间自回归泊松模型进一步考察了创新环境各要素对城市创新空间的影响及其变化。研究发现:(1)2005—2020年深圳市专利申请数量快速增长,创新产出呈现出空间不均衡现象,创新空间结构经历了从“龙岗—南山双核心”向“南山—福田双核心、轴带状”的演化过程。(2)在创新生产要素方面,产业园区扮演着最重要的角色,信息科技企业替代制造业企业成为创新驱动的核心力量;同时,高校/科研机构也正向显著影响着创新产出。(3)在创新生产要素空间位置选择的相关因素方面,区域交通枢纽、区位与交通可达性均显著影响创新空间;不同类型公共服务设施对创新产出的影响存在时间阶段差异。

关键词：创新空间空间集聚专利申请数信息科技企业产业园区产业转型升级空间自回归泊松模型

Noncausal relationship between body weight and breast cancer based on bidirectional Mendelian randomization evidence

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Oncology and Translational Medicine 2024年第05期 245-251页

作者： Qiuhua Li Ying wang Lu Ren Zhaozhe Liu The Post-doctoral Research Station Liaoning University of Traditional Chinese Medicine Department of Oncology Shenzhen Hospital(Futian)of Guangzhou University of Chinese Medicine Shenzhen Department of Radiology Cancer Hospital of China Medical University Liaoning Cancer Hospital and Institute Department of Subject Liaoning University of Traditional Chinese Medicine Department of Oncology General Hospital of Northern Theater Command

Background: Some observational associations between body weight and breast cancer have attracted attention. However, the causal relationship between these 2 factors remains unclear, and more clinical outcomes are needed for its ***: Based on statistical data from a Genome Wide Association Study, we performed a bidirectional Mendelian randomization analysis to assess the bidirectional causal relationship between body weight and breast cancer using 4 methods, with inverse variance weighting as the primary method. To verify the robustness and reliability of the causal relationship, we performed a sensitivity analysis using horizontal pleiotropy, outlier, and one-by-one elimination ***: The inverse variance weighting results revealed no significant positive causal relationship between body weight and breast ***, the reverse analysis revealed no causal effect of breast cancer on body ***: The relationship between body weight and breast cancer may be attributed to confounding factors.

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Delivery room resuscitation intensity and associated neonatal outcomes of 24^(+0)-31^(+6) weeks'preterm infants in China:a retrospective cross-sectional study

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World Journal of Pediatrics 2024年第1期20卷 64-72页

作者： Si-Lu wang Chun Chen Xin-Yue Gu Zhao-Qing Yin Le Su Si-Yuan Jiang Yun Cao Li-Zhong Du Jian-Hua Sun Jiang-Qin Liu Chuan-Zhong Yang Department of Neonatology Shanghai Key Laboratory of Maternal Fetal MedicineShanghai Institute of Maternal-Fetal Medicine and Gynecologic OncologyShanghai First Maternity and Infant HospitalSchool of MedicineTongji UniversityNo.2699Gaoke Western RoadPudong DistrictShanghai 201204China Department of Neonatology Affiliated Shenzhen Maternity and Child Healthcare HospitalSouthern Medical UniversityNo.2004Hongli RoadFutian DistrictShenzhen 518028China NHC Key Laboratory of Neonatal Diseases Fudan UniversityChildren's Hospital of Fudan UniversityShanghaiChina Department of Neonatology People's Hospital of DehongKunming Medical UniversityDehongChina Department of Neonatology Children's Hospital of Fudan UniversityShanghaiChina Department of Neonatology Children's HospitalZhejiang University School of MedicineHangzhouChina Department of Neonatology Shanghai Children's Medical CenterSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina

Background The aim of this study was to review current delivery room(DR)resuscitation intensity in Chinese tertiary neonatal intensive care units and to investigate the association between DR resuscitation intensity and short-term outcomes in preterm infants born at 24+0_31+6 weeks gestation age(GA).Methods This was a retrospective cross-sectional *** source population was infants born at 24+0_31+6 weeks'GA who were enrolled in the Chinese Neonatal Network 2019 *** infants were categorized into five groups:(1)regular care;(2)oxygen supplementation and/or continuous positive airway pressure(O2/CPAP);(3)mask ventilation;(4)endotracheal intubation;and(5)cardiopulmonary resuscitation(CPR).The association between DR resuscitation and shortterm outcomes was evaluated by inverse propensity score-weighted logistic *** Of 7939 infants included in this cohort,2419(30.5%)received regular care,1994(25.1%)received O,/CPAP,1436(18.1%)received mask ventilation,1769(22.3%)received endotracheal intubation,and 321(4.0%)received CPR in the *** maternal age and maternal hypertension correlated with a higher need for resuscitation,and antenatal steroid use tended to be associated with a lower need for resuscitation(P<0.001).Severe brain impairment increased significantly with increasing amounts of resuscitation in DR after adjusting for perinatal *** strategies vary widely between centers,with over 50%of preterm infants in eight centers requiring higher intensity *** Increased intensity of DR interventions was associated with increased mortality and morbidities in very preterm infants in *** is wide variation in resuscitative approaches across delivery centers,and ongoing quality improvement to standardize resuscitation practices is needed.

关键词： Cardiopulmonary resuscitation Delivery room Endotracheal intubation Neonatal resuscitation Preterm

考虑人群活动的城市场所洪涝灾害风险动态评估——以深圳市为例

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地理科学 2024年第4期44卷 711-720页

作者：黄晶王子勍戴强王慧敏河海大学商学院江苏南京211100 水灾害防御全国重点实验室江苏南京210098 南京师范大学虚拟地理环境教育部重点实验室江苏南京210023

为了揭示人群动态活动对城市洪涝灾害风险的影响,本文引入场所视角,建立了考虑人群活动的城市场所洪涝灾害风险评估模型,以深圳市福田区4个典型社区为例分析了工作日和休息日的白天、晚上4个时段下不同类型场所的洪涝灾害风险变化。结... 详细信息

为了揭示人群动态活动对城市洪涝灾害风险的影响,本文引入场所视角,建立了考虑人群活动的城市场所洪涝灾害风险评估模型,以深圳市福田区4个典型社区为例分析了工作日和休息日的白天、晚上4个时段下不同类型场所的洪涝灾害风险变化。结果表明:①除危险性以外,频繁的人群活动亦会增加场所的洪涝灾害风险,与人群活动相关的指标权重达0.31;②不同类型场所的洪涝灾害风险差异显著,且随着人群活动动态变化,生活场所平均风险最高,在4个时段波动较小;居住型混合场所洪涝平均风险次之,但晚上时段比白天高25%左右;商业场所、公共服务场所和办公型混合场所平均风险也较高,在工作日白天高于其他时段;绿色休闲场所在4个时段风险都最低;③居住型社区和综合型社区的洪涝风险存在显著差异,居住型社区为持续性高风险社区,其高风险场所占比在4个时段均超过40%,尤其在晚上达60%,而综合型社区风险呈现出工作日白天高于其他时段的特征,其高风险场所比例最高达54%。

关键词：城市洪涝灾害风险评估场所人群活动

Biomimetic natural biomaterials for tissue engineering and regenerative medicine:new biosynthesis methods,recent advances,and emerging applications

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Military Medical Research 2024年第1期11卷 50-79页

作者： Shuai Liu Jiang-Ming Yu Yan-Chang Gan Xiao-Zhong Qiu Zhe-Chen Gao Huan wang Shi-Xuan Chen Yuan Xiong Guo-Hui Liu Si-En Lin Alec McCarthy Johnson V.John Dai-Xu Wei Hong-Hao Hou Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering the Fifth Affiliated HospitalSchool of Basic Medical ScienceSouthern Medical UniversityGuangzhou 510900China Department of Orthopedics Tongren HospitalShanghai Jiao Tong UniversityShanghai 200336China The Eighth Affiliated Hospital Sun Yat-Sen UniversityShenzhen 518033GuangdongChina Engineering Research Center of Clinical Functional Materials and Diagnosis&Treatment Devices of Zhejiang Province Wenzhou InstituteUniversity of Chinese Academy of SciencesWenzhou 325011ZhejiangChina Department of Orthopedics Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Orthopaedics and Traumatology Faculty of Medicinethe Chinese University of Hong KongHong Kong SAR 999077China Department of Functional Materials Terasaki Institute for Biomedical InnovationLos AngelesCA 90064USA Mary&Dick Holland Regenerative Medicine Program College of MedicineUniversity of Nebraska Medical CenterOmahaNE 68130USA Zigong Affiliated Hospital of Southwest Medical University Zigong Psychiatric Research CenterZigong Institute of Brain ScienceZigong 643002SichuanChina Key Laboratory of Resource Biology and Biotechnology in Western China Ministry of EducationSchool of MedicineDepartment of Life Sciences and MedicineNorthwest UniversityXi’an 710127China

Biomimetic materials have emerged as attractive and competitive alternatives for tissue engineering(TE)and regenerative *** contrast to conventional biomaterials or synthetic materials,biomimetic scaffolds based on natural biomaterial can offer cells a broad spectrum of biochemical and biophysical cues that mimic the in vivo extracellular matrix(ECM).Additionally,such materials have mechanical adaptability,micro-structure interconnectivity,and inherent bioactivity,making them ideal for the design of living implants for specific applications in TE and regenerative *** paper provides an overview for recent progress of biomimetic natural biomaterials(BNBMs),including advances in their preparation,functionality,potential applications and future *** highlight recent advances in the fabrication of BNBMs and outline general strategies for functionalizing and tailoring the BNBMs with various biological and physicochemical characteristics of native ***,we offer an overview of recent key advances in the functionalization and applications of versatile BNBMs for TE ***,we conclude by offering our perspective on open challenges and future developments in this rapidly-evolving field.

关键词： Biomimic Scaffold Biosynthesis Natural biomaterial Tissue engineering

基于耕地发展权价值测算的陕西省耕地保护补偿研究

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农业工程学报 2018年第22期34卷 256-266页

作者：张浩靳亚亚王博冯淑怡曲福田南京农业大学中国土地问题研究中心南京210095 浙江大学土地与国家发展研究院杭州310058

基于耕地发展权价值视角测算耕地保护补偿价值,建立耕地保护补偿机制,有利于明确耕地保护权责、调动耕地保护主体的积极性、促进各区域经济发展和耕地保护的均衡和谐。因此,为准确测量耕地发展权价值,建立起融合耕地发展权价值在内的耕... 详细信息

基于耕地发展权价值视角测算耕地保护补偿价值,建立耕地保护补偿机制,有利于明确耕地保护权责、调动耕地保护主体的积极性、促进各区域经济发展和耕地保护的均衡和谐。因此,为准确测量耕地发展权价值,建立起融合耕地发展权价值在内的耕地保护补偿机制,该文以陕西省为例,基于耕地发展权价值测算视角,构建耕地发展权价值测算方法体系,测算了耕地盈亏平衡和耕地发展权价值,最终依据该价值确定出相应的补给和受偿情况。研究结果表明:1)2015年陕西省总体处于耕地亏损区,总赤字面积为39.52×10~4 hm^2,人均耕地赤字面积为0.0136 hm^2,耕地总面积赤字率为9.89%;2)在省级层面,陕西省现实耕地发展权价值为50.57元/m^2,考虑到陕西省耕地盈亏量,陕西省总体耕地发展权价值处于亏损状态,因此在国家未给予政策优惠的情况下实际需要支付1998.50亿元的耕地发展权资金;3)在地级市层面,西安市、汉中市、商洛市、延安市、安康市和铜川市6市(亏损程度从重到轻排序)处于耕地发展权价值补给区域,而榆林市、渭南市、宝鸡市和咸阳市4市(盈余程度从高到低排序)则处于耕地发展权价值受偿区域。

关键词：土地利用农产品耕地保护补偿耕地发展权价值陕西省

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农户土地和劳动力资源配置决策及其影响因素

资源科学 2022年第8期44卷 1577-1588页

作者：吕沛璐冯淑怡王博曲福田南京农业大学公共管理学院南京210095 南京农业大学中国资源环境与发展研究院南京210095

推动农村农地流转和劳动力转移有序健康发展是中国全面深化农村改革、实现乡村振兴的重要内容。本文利用江苏、江西、辽宁和重庆的1248户农户实地调查数据,运用双变量有序probit模型,实证分析了农户农地流转和劳动力转移决策行为的相关... 详细信息

推动农村农地流转和劳动力转移有序健康发展是中国全面深化农村改革、实现乡村振兴的重要内容。本文利用江苏、江西、辽宁和重庆的1248户农户实地调查数据,运用双变量有序probit模型,实证分析了农户农地流转和劳动力转移决策行为的相关关系及其影响因素。研究表明:(1)农户农地流转和劳动力转移决策行为之间具有显著的正向相关关系,农户对土地和劳动力资源的配置决策具有方向一致性的特征。(2)农户农地流转和劳动力转移决策行为受到若干因素的显著影响。农户拥有的人力资本(劳动力数量、劳动力健康、劳动力教育、劳动力年龄、劳动力农业技能培训、受抚养子女比例和老年人比例)、社会资本(劳动力非农务工经验)、自然资本(承包地面积)、物质资本(耐用消费品资产、农业生产性固定资产)以及所在地外部环境特征(村庄农地流转情况、劳动力非农务工情况)都会显著影响农户农地流转和劳动力转移决策行为。本文认为,在农村经济结构转型升级、乡村振兴战略全面推进的新发展格局下,政府应为农村农地流转市场和劳动力市场的协调发展提供相应的政策支持,注重农户不同类型生计资本的数量积累和质量提升,从而进一步提高农户农地流转和劳动力转移的积极性和稳定性。

关键词：农地流转劳动力转移农户决策资源配置影响因素生计资本双变量有序probit模型