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Effectivity and safety of trifocal intraocular lenses and capsular tension rings implantation for cataract patients with axial high myopia

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 499-508页

作者： shan Hua Qiu-Xia Xie Hu wang Jing-Xiang Zhong Dongguan Aier Eye Hospital Jinan UniversityDongguan 523106Guangdong ProvinceChina Department of Ophthalmology the First Affiliated Hospital of Jinan UniversityGuangzhou 510630Guangdong ProvinceChina Department of Ophthalmology the Sixth Affiliated Hospital of Jinan UniversityDongguan 523576Guangdong ProvinceChina

●AIM:To assess effectivity and safety of trifocal intraocular lenses(IOLs)and capsular tension rings in treating cataract patients with axial high myopia.●METHODS:A prospective nonrandomized controlled clinical trial was *** 98 eyes(74 patients)who underwent femtosecond laser-assisted cataract surgery(FLACS)with trifocal IOLs were enrolled in the study and followed up for 2y after surgery:46 eyes(33 patients)with capsular tension ring implantation in the long axial lengths(AL)group(260.05).The dysfunctional lens index and total modulation transfer function(MTF)average height were similar between the two *** postoperative internal coma aberrations in the axial high myopia eyes were significantly higher than that in the normal AL group(P<0.05).The total satisfaction score in the long AL group(91.32±2.76)was slightly higher than that in the normal AL group(90.36±3.47),but there was no difference(P=0.136).A statistically negative correlation was found between corrected distance visual acuity(CDVA)and dysfunctional lens index(r=-0.382,P=0.009),and between CDVA and the total MTF average height(r=-0.374,P=0.01).But there was no significant correlation between CDVA and total satisfaction score(r=0.059,P=0.696).Postoperative complications mainly presented as posterior capsular opacity(PCO),retinal detachment and cystoid macular *** was no difference in the incidenc

关键词： trifocal intraocular lenses capsular tension ring axial high myopia cataract visual quality

Two-dimensional precise figuring of 500 mm-long X-ray mirror using one-dimensional ion beam system

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Advances in Manufacturing 2024年第1期12卷 177-184页

作者： Qiu-Shi Huang Han-Dan Huang Qiao-Yu Wu Jun Yu Zhong Zhang Zhan-shan wang MOE Key Laboratory of Advanced Micro-Structured Materials Institute of Precision Optical Engineering(IPOE)School of Physics Science and EngineeringTongji UniversityShanghai200092People’s Republic of China shanghai Professional Technical Service Platform for Full-Spectrum and High-Performance Optical Thin Film Devices and Applications Tongji UniversityShanghai200092People’s Republic of China shanghai Frontiers Science Center of Digital Optics Tongji UniversityShanghai200092People’s Republic of China

In this study,a new method was developed to realize two-dimensional(2D)figure correction of grazing-incidence X-ray mirrors using a one-dimensional(1D)ion-beam figuring system.A mask of holes was specifically designed to generate removal functions at different widths and extend the figuring capability over a wide ***,a long mirror could be *** this method,the surface height root-mean-square(RMS)error of the center area of 484 mm×16 mm was reduced from 11.49 nm to 2.01 nm,and the 1D meridional RMS error reached 1.0 *** proposed method exhibits high precision and cost effectiveness for production of long X-ray mirrors.

关键词： Long-size mirrors Ion beam figuring Two-dimensional figure correction Mask

IGF2BPs as novel m^(6)A readers:Diverse roles in regulating cancer cell biological functions,hypoxia adaptation,metabolism,and immunosuppressive tumor microenvironment

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Genes & Diseases 2024年第2期11卷 890-920页

作者： Meiqi Duan Haiyang Liu Shasha Xu Zhi Yang Fusheng Zhang Guang wang Yutian wang shan Zhao Xiaofeng Jiang Department of General Surgery The Fourth Affiliated Hospital of China Medical UniversityShenyangLiaoning 110032China Department of Gastroendoscopy The Fourth Affiliated Hospital of China Medical UniversityShenyangLiaoning 110032China Department of Rheumatology and Immunology The First Affiliated Hospital of China Medical UniversityShenyangLiaoning 110002China

m^(6)A methylation is the most frequent modification of mRNA in eukaryotes and plays a crucial role in cancer progression by regulating biological ***-like growth factor 2 mRNA-binding proteins(IGF2BP)are newly identified m^(6)A‘readers’.They belong to a family of RNA-binding proteins,which bind to the m^(6)A sites on different RNA sequences and stabilize them to promote cancer *** this review,we summarize the mechanisms by which different upstream factors regulate IGF2BP in *** current literature analyzed here reveals that the IGF2BP family proteins promote cancer cell proliferation,survival,and chemoresistance,inhibit apoptosis,and are also associated with cancer glycolysis,angiogenesis,and the immune response in the tumor ***,with the discovery of their role as‘readers’of m^(6)A and the characteristic re-expression of IGF2BPs in cancers,it is important to elucidate their mechanism of action in the immunosuppressive tumor *** also describe in detail the regulatory and interaction network of the IGF2BP family in downstream target RNAs and discuss their potential clinical applications as diagnostic and prognostic markers,as well as recent advances in IGF2BP biology and associated therapeutic value.

关键词： Cancer IGF2BP Immunosuppressive TME m^(6)A Molecular mechanism Therapy

Tuning the exciton binding energy of covalent organic frameworks for efficient photocatalysis

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Chinese Chemical Letters 2024年第2期35卷 577-583页

作者： Zhangjie Gu Zhen shan Yulan wang Jinjian wang Tongtong Liu Xiaoming Li Zhiyang Yu Jian Su Gen Zhang Key Laboratory for Soft Chemistry and Functional Materials of Ministry of Education School of Chemistry and Chemical EngineeringNanjing University of Science and TechnologyNanjing 210094China State Key Laboratory of Photocatalysis on Energy and Environment College of ChemistryFuzhou UniversityFuzhou 350002China MIIT Key Laboratory of Advanced Display Material and Devices School of Materials Science and EngineeringNanjing University of Science and TechnologyNanjing 210094China Key Laboratory of Preclinical Study for New Drugs of Gansu Province School of Basic Medical SciencesLanzhou UniversityLanzhou 730000China

Owing to the large exciton binding energy(>100 meV)of most organic materials,the process of exciton dissociation into free electrons and holes is seriously hindered,which plays a key role in the photocatalytic *** this study,a series of chalcogen(S,Se)-substituted mesoporous covalent organic frameworks(COFs)have been synthesized for enhanced photocatalytic organic *** measurements indicate that the introduction of semi-metallic Se atom and the enlargement of conjugation degree can not only reduce the exciton binding energy accelerating the charge separation,but also reduce the band gap of *** a result,the COF-NUST-36 with the lowest exciton binding energy(39.5 meV)shows the highest photocatalytic performance for selective oxidation of amines(up to 98%*** 97.5%Sel.).This work provides a feasible method for designing COFs with high photocatalytic activity by adjusting exciton binding energy.

关键词： Covalent organic frameworks Exciton binding energy Atom substitution Extended conjugation Photocatalysis

Double-nylon purse-string suture in closing postoperative wounds following endoscopic resection of large(≥3 cm)gastric submucosal tumors

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World Journal of Gastroenterology 2024年第9期30卷 1143-1153页

作者： shan-shan wang Meng-Yao Ji Xu Huang Yan-Xia Li Shi-Jie Yu Yu Zhao Lei Shen Department of Gastroenterology Renmin Hospital of Wuhan UniversityWuhan 430000Hubei provinceChina

BACKGROUND Endoscopic full-thickness resection(EFTR)of gastric submucosal tumors(SMTs)is safe and effective;however,postoperative wound management is equally *** on suturing following EFTR for large(≥3 cm)SMTs is scarce and *** To evaluate the efficacy and clinical value of double-nylon purse-string suture in closing postoperative wounds following EFTR of large(≥3 cm)*** We retrospectively analyzed the data of 85 patients with gastric SMTs in the fundus of the stomach or in the lesser curvature of the gastric body whose wounds were treated with double-nylon purse-string sutures after successful tumor resection at the Endoscopy Center of Renmin Hospital of Wuhan *** operative,postoperative,and follow-up conditions of the patients were *** All tumors were completely resected using EFTR.36(42.35%)patients had tumors located in the fundus of the stomach,and 49(57.65%)had tumors located in the body of the *** patients underwent suturing with double-nylon sutures after EFTR without laparoscopic assistance or further surgical *** fever and stomach pain were reported in 13(15.29%)and 14(16.47%)patients,*** serious adverse events occurred during the intraoperative or postoperative periods.A postoperative review of all patients revealed no residual or recurrent *** Double-nylon purse-string sutures can be used to successfully close wounds that cannot be completely closed with a single nylon suture,especially for large(≥3 cm)EFTR wounds in SMTs.

关键词： Endoscopic full-thickness resection Purse-string suture Postoperative wounds Submucosal tumors

When quantum dots meet blue phase liquid crystal elastomers:visualized full-color and mechanically-switchable circularly polarized luminescence

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Light(Science & Applications) 2024年第6期13卷 1210-1220页

作者： shan Li Yuqi Tang Qingyan Fan Ziyuan Li Xinfang Zhang Jingxia wang Jinbao Guo Quan Li Key Laboratory of Carbon Fibers and Functional Polymers Ministry of Educationand College of Materials Science and EngineeringBeijing University of Chemical Technology100029BeijingChina Institute of Advanced Materials and School of Chemistry and Chemical Engineering Southeast UniversityNanjing211189China Materials Science Graduate Program Kent State UniversityKentOH44242USA CAS Key Laboratory of Bio-Inspired Materials and Interfacial Sciences Technical Institute of Physics and ChemistryChinese Academy of Sciences100190BeijingChina

Polymer-based circularly polarized luminescence(CPL)materials with the advantage of diversified structure,easy fabrication,high thermal stability,and tunable properties have garnered considerable ***,adequate and precise tuning over CPL in polymer-based materials remains challenging due to the difficulty in regulating chiral ***,visualized full-color CPL is achieved by doping red,green,and blue quantum dots(QDs)into reconfigurable blue phase liquid crystal elastomers(BPLCEs).In contrast to the CPL signal observed in cholesteric liquid crystal elastomers(CLCEs),the chiral 3D cubic superstructure of BPLCEs induces an opposite CPL ***,this effect is entirely independent of photonic bandgaps(PBGs)and results in a high glum value,even without matching between PBGs and the emission bands of ***,the lattice structure of the BPLCEs can be reversibly switched via mechanical stretching force,inducing on-off switching of the CPL signals,and these variations can be further fixed using dynamic disulfide bonds in the ***,the smart polymer-based CPL systems using the BPLCEs for anti-counterfeiting and information encryption have been demonstrated,suggesting the great potential of the BPLCEs-based CPL active materials.

关键词： circular quantum crystal

A Three-Dimensional DEM Method for Trajectory Simulations of Rockfall under Irregular-Shaped Slope Surface and Rock Blocks

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Journal of Earth Science 2024年第1期35卷 306-312页

作者： Liang Chen Weiqian Zeng Xianbiao wang Yang Ye Yunfeng Ge Dongming Gu shan Dong Huadong Engineering Corporation Limited Fuzhou 350003China Faculty of Engineering China University of GeosciencesWuhan 430074China Badong National Observation and Research Station of Geohazards China University of GeosciencesWuhan 430074China

0 *** is a common geological hazard that poses a serious threat to residents and infrastructures(Gao et al.,2022;Ye et al.,2022).The precise prediction of rockfall trajectories is essential to the design of protection engineering structures of rockfall(Ma et al.,2021).The discrete element modelling(DEM)is increasingly used to analyse rockfall movement *** et al.(2022)used Rockyfor3D software to obtain the possible trajectory of falling rock blocks.

关键词： rock prediction hazard

Improved Weighted Local Contrast Method for Infrared Small Target Detection

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Journal of Beijing Institute of Technology 2024年第1期33卷 19-27页

作者： Pengge Ma Jiangnan wang Dongdong Pang Tao shan Junling Sun Qiuchun Jin School of Intelligent Engineering Zhengzhou University of AeronauticsZhengzhou 450000China Beijing Key Laboratory of Fractional Signals and Systems School of Information and ElectronicsBeijing Institute of TechnologyBeijing 100081China

In order to address the problem of high false alarm rate and low probabilities of infrared small target detection in complex low-altitude background,an infrared small target detection method based on improved weighted local contrast is proposed in this ***,the ratio information between the target and local background is utilized as an enhancement *** local contrast is calculated by incorporating the heterogeneity between the target and local ***,a local product weighted method is designed based on the spatial dissimilarity between target and background to further enhance target while suppressing ***,the location of target is obtained by adaptive threshold *** experimental results demonstrate,the method shows superior performance in several evaluation metrics compared with six existing algorithms on different datasets containing targets such as unmanned aerial vehicles(UAV).

关键词： infrared small target unmanned aerial vehicles(UAV) local contrast target detection

Paleoenvironmental reconstruction and organic matter accumulation of the paleogene shahejie oil shale in the Zhanhua Sag, Bohai Bay Basin, Eastern China

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Petroleum Science 2024年第3期21卷 1552-1568页

作者： Xiao-Lin wang Xiao-Min Zhu Jin Lai Xing-Yue Lin Xiang wang Yu-shan Du Chao Huang Yu-Rui Zhu State Key Laboratory of Petroleum Resources and Engineering China University of Petroleum(Beijing)Beijing102249China College of Geosciences China University of Petroleum(Beijing)Beijing102249China Shengli Oilfield SINOPECDongying257000ShandongChina

The controlling factors of organic-rich shale accumulation is essential for the exploration and development of shale oil and gas *** sedimentary environment plays a vital role in the formation of organic-rich sediments in lacustrine *** article unravels the mineralogy,geochemistry,and paleoenvironmental evolution during the deposition of the Paleogene Shahejie Formation(Es3L).It discusses the effects of paleoclimate,paleosalinity,paleoredox conditions,paleowater depth,and paleoproductivity on organic matter(OM)***,the OM enrichment model was *** results show that the mineralogical compositions are mainly composed of calcite(avg.40.13%),quartz(avg.21.64%)and clay minerals(avg.24.07%),accompanied by dolomite(avg.7.07%),feldspar(avg.6.36%)and pyrite(avg.2.95%).The Es3Lshale has a high abundance of OM,with total organic carbon(TOC)ranging from 1.07%to 5.12%.The organic matter type is mainly composed of type I-II1kerogen,which is generally considered a good-quality source *** source of OM is a mixture of lower bacteria,algae,and *** the early sedimentary period,the paleoclimate was dry and cold,with high salinity,intense reducibility,and relatively low *** the late sedimentary period,the climate became warmer and more *** a result,the salinity decreased to a level that was suitable for biological reproduction,and productivity increased gradually due to the input of terrigenous *** and paleoclimate determined the environment of the sedimentary period,in addition,paleoproductivity and paleoredox condition indicated the formation and preservation conditions of *** warm and humid climate,brackish water,suitable reduction conditions and high productivity are the favorable conditions for the generation and preservation of organic *** research results may have implications for the genetic mechanisms of organic matter *** will provide theoretical and technica

关键词： Elemental geochemical Paleoenvironment Organic matter accumulation Paleogene shahejie formation Zhanhua Sag Bohai Bay Basin