检索结果-南通市图书馆

Efficacy of Wen-Luo-Tong on Peripheral Neuropathy Induced by Chemotherapy or Target Therapy: A Randomized, Double-Blinded, Placebo-Controlled Trial

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2022年第7期28卷 579-585页

作者： DENG Bo JIA Li-qun WAN Dong-gui wang bao-yi CHENG Zhi-qiang DENG Chao Center of Science and Technology China-Japan Friendship HospitalBeijing 100029China Integrative Oncology Department of Chinese Medicine and Western Medicine China-Japan Friendship HospitalBeijing 100029China

Objective: To evaluate the efficacy of Wen-Luo-Tong Granules(WLT) local administration in the treatment of patients with peripheral neuropathy(PN) induced by chemotherapy or target therapy. Methods: This study is a randomized, double-blinded, and placebo-controlled trial. Seventy-eight patients with PN induced by chemotherapy or target therapy were enrolled from China-Japan Friendship Hospital between July 2019 and January 2020. They were randomly assigned to WLT(39 cases) and control groups(39 cases) using a block randomization method. The WLT group received WLT(hand and foot bath) plus oral Mecobalamin for 1 week, while the control group received placebo plus oral Mecobalamin. The primary endpoint was PN grade evaluated by the National Cancer Institute-Common Toxicity Criteria for Adverse Events(NCI-CTCAE). The secondary endpoints included quantitative touch-detection threshold, neuropathy symptoms, Quality of Life QuestionnaireChemotherapy Induced Peripheral Neuropathy(QLQ-CIPN20), and Quality of Life Questionnaire-Core30(QLQ-C30). Results: After treatment, the PN grade in the WLT group was significantly lower than that in the control group(1.00±0.29 vs. 1.75±0.68, P<0.01). The total effective rate in the WLT group was significantly higher than that in the control group(82.05% vs. 51.28%, P<0.01). Compared with the control group, the touchdetection thresholds at fingertips, neuropathy symptom score, QLQ-CIPN 20(sensory scale, motor scale, autonomic scale, and sum score), and QLQ-C30(physical functioning, role functioning, emotional functioning, and global health) in the WLT group significantly improved after treatment(P<0.01 or P<0.05). Conclusion: WLT local administration was significantly effective in the treatment of patients with PN induced by chemotherapy or target therapy.(Trial registration No. ChiCTR1900023862)

关键词： peripheral neuropathy chemotherapy target therapy Chinese medicine Wen-Luo-Tong randomized controlled trial

Synergistic Effect of Triple Ion Beams on Radiation Damage in CLAM Steel

在线全文

学校读者我要写书评

暂无评论

Chinese Physics Letters 2014年第4期31卷 93-95页

作者： YUAN Da-Qing ZHENG Yong-Nan ZUO yi FAN Ping ZHOU Dong-Mei ZHANG Qiao-Li MA Xiao-Qiang CUI bao-Qun CHEN Li-Hua JIANG Wei-Sheng WU yi-Can ttUANG Qun-ying PENG Lei CAO Xing-Zhong wang bao-yi WEI Long ZHU Sheng-Yun China Institute of Atomic Energy Beijing 102413 Institute of Nuclear Energy Safety Technology Chinese Academy of Sciences Hefei 230031 Institute of High Energy Physics Chinese Academy of Sciences Beijing 100039

The synergistic effect of triple ion beams is investigated by simultaneous and scquential irradiations of gold, hydrogen and helium ions on the low activation martensitie steel （CLAM） developed in China. The depth profile measurements of the positron annihilation Doppler broadening S parameter are carried out as a function of slow- positron beam energy to examine the produced radiation damage. The synergistic effect of displacement damage and hydrogen and helium on the formation of radiation damage is clearly observed. In the preset case ,this effect suppresses the radiation damage in the CLAM steel due to the helium and/or hydrogen filling of vacancy clusters.

关键词： HELIUM ions HYDROGEN MARTENSITIC stainless steel POSITRON annihilation RADIATION damage

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics Letters 2012年第4期29卷 206-209页

作者： LI Yue DENG Ai-Hong ZHOU Yu-Lu ZHOU Bing wang Kang HOU Qing SHI Li-Qun QIN Xiu-Bo wang bao-yi Department of Physics Sichuan UniversityChengdu 610064 Key Laboratory of Radiation Physics and Technology of Ministry of Education Institute of Nuclear Science and TechnologySichuan UniversityChengdu 610064 Institute of Modern Physics Fudan UniversityShanghai 200433 Laboratory of Nuclear Analysis Technique Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049

Various helium-containing titanium films were deposited on Si substrates by magnetron sputtering under different helium/argon (He/Ar) *** concentrations and corresponding depth profiles in the Ti films are obtained by elastic recoil detection analysis (ERDA).X-ray diffraction (XRD) measurements are carried out to evaluate the crystallization of the titanium ***-type defects and their depth profiles were revealed by slow positron beam analysis (SPBA).It is found that the defect-characteristic parameter S rises with the increment of the He/Ar flow *** variation of S indicates the formation and evolution of various Herelated defects,with uniform distribution into the depth around 400nm.

关键词： titanium Titanium increment

Anomalous change of the Antarctic sea ice and global sea level change

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Oceanologica Sinica 1996年第2期15卷 193-208页

作者： Xie Simei Zou Bing wang yi and bao Chenglan (National Marine Environment Forecasting Center, State oceanic Administration, Beijing 100081, China) National Marine Environment Forecasting Center State Oceanic Administration Beijing 100081 China

In this paper, the long-term variation trend of the Antarctic sea ice in 1973～1994 and the inter-decade variation rule of the global sea level are analyzed. It is found that the sea ice area in the Antarctic in the 1980s was significantly less than in the 1970s and the average global sea level height value in the 1980s was also significantly higher than in the 1970s. Connecting variation of both and analyzing their physical mechanism, it indicates that the accumulated sea ice anomaly value in the 1980s less than in the 1970s means a global climate warming, the sea water temperature and air temperature were obviously higher in the 1980s it introduced the long-term accumulated sea ice decreased greatly; a higher sea water temperature introduced sea water volume expanding, and more icebergs transporting from the ice cover in the Antarctic continent to ocean in the warmer year. As a result induced by these multi-causes, the global sea level raised significantly in the 1980s. The global average sea level value in the 1980s, was 22 mm higher than in the 1970s. The sea level raising(SLR) was distributed unevenly. It is especially true in the Pacific Ocean with two expensive we level raising regions in the Northeast Pacific and Southeast Pacific as well as a raising region near the Bering Sea; and with two descent regions in the Northwest and Southwest Pacific. It is considered that this kind of uneven SLR distribution closely relates to the sustained decreasing of the Antarctic sea ice. The higher sea water tem This study was supported both by the National Natural Science Foundation of China under contrast Nod 49376252 and by the National '85' Plan 'Key Project 903': 7th *** in the south ocean introduces a rather warmer water temperature of the Peru Cold Current which is a northward branch of the South Oceanic Current along the South American continent, then it is easier to the occurrence of El Nino event. When El Nino event occurs, the prevailed tropical easte

关键词： Antarctic sea ice global sea level long-term variation El Nino event oceanic circulation

Interaction of Hypocrellin B or Mono-cysteine Substituted Hypocrellin B with CT-DNA by Spectral Methods

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2003年第10期14卷 1054-1057页

作者： Jia Hong ZHOU, Sheng Qin XIA,Xue Song wang, bao Wen ZHANG, yi CAO Technical Institute of Physics and Chemistry, Chinese Academy of Sciences,Beijing 100101 Technical Institute of Physics and Chemistry Chinese Academy of Sciences

The interaction of the anticancer drug hypocrellin B (HB) or the mono-cysteine substituted hypocrellin B (MCHB) and calf thymus deoxyribonucleic acid (CT-DNA) has been investigated using spectral methods. The results of UV-visible spectra show that the HB and MCHB could intercalate into the base-stacking domain of the CT-DNA double helix. The studies of fluorescence spectra and circular dichroism(CD) spectra also support the interacalation mechanism.

关键词： Hypocrellin B mono-cysteine substituted hypocrellin B CT-DNA interacalation mechanism.

重型柴油机Urea-SCR系统控制策略建模与仿真研究

在线全文

学校读者我要写书评

暂无评论

内燃机工程 2015年第4期36卷 46-52页

作者：王谦王保义江苏大学能源与动力工程学院镇江212013

针对重型柴油机选择性催化还原(selective catalytic reduction,SCR)系统,基于质量及能量守恒定律,推导出催化器内部各组分的数学控制表达式,并在MATLAB/Simulink软件中建立SCR催化转化器模型、SCR开环控制模型及SCR闭环控制模型。通过... 详细信息

针对重型柴油机选择性催化还原(selective catalytic reduction,SCR)系统,基于质量及能量守恒定律,推导出催化器内部各组分的数学控制表达式,并在MATLAB/Simulink软件中建立SCR催化转化器模型、SCR开环控制模型及SCR闭环控制模型。通过对SCR开环控制模型的欧洲稳态测试循环(European steady state cycle,ESC)发现,与试验结果相比,除个别工况外,NOx转化效率的模拟结果误差均控制在10%之内,符合精度要求。通过对闭环控制模型的欧洲瞬态循环(European transient cycle,ETC)测试发现,虽然NOx转化效率提高幅度较小,但是NH3的平均泄漏量大幅度降低,为开环控制中NH3平均泄漏量的60%,NH3泄漏峰值也大幅度降低。

关键词：内燃机柴油机 SCR催化转化器控制策略 NOx转化效率

Bias Effects on the Growth of Helium-Containing Titanium Films

在线全文

学校读者我要写书评

暂无评论

Chinese Physics Letters 2011年第7期28卷 286-289页

作者： ZHANG Li-Ran DENG Ai-Hong YANG Dong-Xu ZHOU Yu-Lu HOU Qing SHI Li-Qun ZHONG Yu-Rong wang bao-yi Department of Physics Sichuan UniversityChengdu 610064 Key Laboratory of Radiation Physics and Technology of the Ministry of Education Institute of Nuclear Science and TechnologySichuan UniversityChengdu 610064 Institue of Modern Physics Fudan UniversityShanghai 200433 Laboratory of Nuclear Analysis Technique Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049

Helium-containing titanium films were prepared on Si substrates with various biases applied by magnetron sputtering under stable He/Ar *** backscattering and elastic recoil detection analyses are used to measure the thickness of the He-Ti films and the helium depth profile,*** of x-ray diffraction and variable energy positron annihilation spectroscopy are carried out to investigate the microstructures of titanium films and the corresponding helium-related defects *** behavior of the implanted He,the microstructure of the He-Ti film and the formation of He-related defects all are affected by the substrate biases applied.

关键词： microstructure titanium Titanium

供给侧改革的动因与规制研究:基于政府与市场的博弈关系

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国软科学 2018年第3期 76-85页

作者：王赫奕王义保中国矿业大学公共管理学院江苏徐州221000

供给侧改革作为当今的热点话题之一,对我国今后的紧急发展有着至关重要的影响。政府作为供给侧改革的实施者,推行供给侧改革具有深刻的动因。旧常态下全面政府的博弈组合模式不再能适应新常态的大环境,使得经济增速下降,此时的政府在博... 详细信息

供给侧改革作为当今的热点话题之一,对我国今后的紧急发展有着至关重要的影响。政府作为供给侧改革的实施者,推行供给侧改革具有深刻的动因。旧常态下全面政府的博弈组合模式不再能适应新常态的大环境,使得经济增速下降,此时的政府在博弈之中需要对市场做出适当的让步,恢复与"强市场"的并存的均衡路径,通过对两部门模型的分析,找到供给侧改革的关键所在。并且供给侧改革的实施者——政府对微观经济体的规制也需要革新。如此,在实现有限政府与有效市场的良性互动的条件下,才能使得供给侧结构性改革得以有效实施。

关键词：博弈帕累托最优两部门模型规制互动

在线全文

学校读者我要写书评

暂无评论

中国特色多党合作和政治协商制度发展30年

山东社会科学 2008年第9期 14-19页

作者：王义保中国矿业大学文法学院江苏徐州221116

改革开放30年来,中国共产党领导的多党合作和政治协商制度取得了制度发展与建设的巨大成就。总结我国这一基本政治制度的发展成就与成功经验,科学认识我国政党制度的特点和优势,对于进一步坚定和完善我国特色多党合作和政治协商制度建... 详细信息

改革开放30年来,中国共产党领导的多党合作和政治协商制度取得了制度发展与建设的巨大成就。总结我国这一基本政治制度的发展成就与成功经验,科学认识我国政党制度的特点和优势,对于进一步坚定和完善我国特色多党合作和政治协商制度建设具有重大的理论与现实意义。

关键词：多党合作制度成就经验