检索结果-南通市图书馆

基于脉冲序列标识的深度脉冲神经网络时空反向传播算法

在线全文

学校读者我要写书评

暂无评论

电子与信息学报 2024年第6期46卷 2596-2604页

作者：王子华叶莹刘洪运许燕樊瑜波王卫东北京航空航天大学生物与医学工程学院北京100191 中国人民解放军总医院医学创新研究部生物工程研究中心北京100853 工业和信息化部生物医学工程与转化医学重点实验室北京100853 华北计算技术研究所北京100083

尖峰放电的脉冲神经网络(SNN)具有接近大脑皮层的信号处理模式,被认为是实现大脑启发计算的重要途径。但是,目前对于深度脉冲神经网络的学习仍缺乏有效的监督学习算法。受尖峰放电速率标识的时空反向传播算法的启发,该文提出一种面向深... 详细信息

尖峰放电的脉冲神经网络(SNN)具有接近大脑皮层的信号处理模式,被认为是实现大脑启发计算的重要途径。但是,目前对于深度脉冲神经网络的学习仍缺乏有效的监督学习算法。受尖峰放电速率标识的时空反向传播算法的启发,该文提出一种面向深度脉冲神经网络训练的基于时间脉冲序列标识的监督学习算法,通过定义突触后电位和膜电位反传迭代因子分别分析脉冲神经元的空间和时间依赖关系,使用替代梯度的方法解决反传过程中不连续可微的问题。不同于现有基于尖峰放电速率标识的学习算法,该算法能够充分反映脉冲神经网络输出的时间脉冲序列的动态特性。因此,所提算法非常适合应用于需要较长时间序列标识的计算任务,例如行为的时间脉冲序列控制。该文在静态图像数据集CIFAR10和神经形态数据集NMNIST上验证了所提算法的有效性,在所有这些数据集上都显示出良好的性能,这有助于进一步研究基于时间脉冲序列应用的大脑启发计算。

关键词：脉冲神经网络监督学习误差反向传播时间脉冲序列标识替代梯度

在线全文

学校读者我要写书评

暂无评论

桑植县产业结构和经济增长的灰色关联分析

科技和产业 2024年第8期24卷 187-192页

作者：王自华韩芳新疆农业大学公共管理学院乌鲁木齐830052

地区产业结构发展的最高阶段呈“三、二、一”形式的结构,即第三产业在国内生产总值中所占比例最大,第二产业次之,第一产业最后的产业结构形式。这是根据“配第-克拉克定理”所得出的结论。数据显示,桑植县目前产业结构中出现第一、二... 详细信息

地区产业结构发展的最高阶段呈“三、二、一”形式的结构,即第三产业在国内生产总值中所占比例最大,第二产业次之,第一产业最后的产业结构形式。这是根据“配第-克拉克定理”所得出的结论。数据显示,桑植县目前产业结构中出现第一、二产业所占GDP比例相差不大,第三产业遥遥领先的局面。产业结构呈现明显的不合理。运用灰色关联分析方法对桑植县产业结构与经济增长进行研究,分析桑植县三次产业与GDP之间的灰色关联度,发现第三产业对桑植县的经济增长的作用最为明显,关联度最高,第二产业与经济的关联度最低,这与“三、二、一”产业结构形式相违背,于是针对第二产业的发展进行分析,在此基础上,为促进桑植县产业结构优化与经济增长提供了相关的对策建议。

关键词：产业结构灰色关联分析桑植县

Solute redistribution and micromechanical properties of rapidly solidified multicomponent Ni-based alloys

在线全文

学校读者我要写书评

暂无评论

Science China(Technological Sciences) 2019年第3期62卷 472-477页

作者： YAN Na wang zihua RUAN Ying WEI BingBo MOE Key Laboratory of Materials Physics and Chemistry under Extraordinary Conditions Department of Applied PhysicsNorthwestern Polytechnical University

The solute trapping effect and microhardness enhancement of quaternary Ni-5%Cu-5%Ag-5%Sn and quinary Ni-5%Cu-5%Ag-5%Sn-5%Ge alloys during rapid dendritic solidification are investigated by glass fluxing technique. In these two alloys, the experimental maximum undercoolings of 310 K(0.18 T_L) and 220 K(0.13 T_L) have been achieved and the rapidly solidified microstructures are composed of α(Ni) and(Ag) solid solution phases. The morphological transition from coarse dendrite into equiaxed structure is observed for α(Ni) phase with the increase of undercooling. The dendritic growth velocity of α(Ni) phase in quaternary Ni-5%Cu-5%Ag-5%Sn alloy is larger than that in quinary Ni-5%Cu-5%Ag-5%Sn-5%Ge alloy, which increases firstly and then decreases with the enhancement of bulk undercooling. The Vickers hardness of α(Ni) phase in these two alloys is enhanced with the increase of undercooling, which is attributed mainly to the grain refinement effect. Meanwhile, the solute trapping effect of Cu, Sn and Ge elements in the α(Ni) phase also contributes to the microhardness enhancement under large undercoolings. The addition of Ge element effectively increases the microhardness of α(Ni) phase due to solute strengthening mechanism.

关键词： high undercooling dendritic growth solute redistribution microhardness enhancement

A novel PD-L1 targeting peptide self-assembled nanofibers for sensitive tumor imaging and photothermal immunotherapy in vivo

在线全文

学校读者我要写书评

暂无评论

Nano Research 2022年第8期15卷 7286-7294页

作者： Linping Fu Jianhu Zhang Chenchen Wu Weizhi wang Dong wang Zhiyuan Hu zihua wang CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety CAS Key Laboratory of Standardization and Measurement for NanotechnologyCAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190China School of Nanoscience and Technology Sino-Danish CollegeUniversity of Chinese Academy of SciencesBeijing 100049China Fujian Provincial Key Laboratory of Brain Aging and Neurodegenerative Diseases School of Basic Medical SciencesFujian Medical UniversityFuzhou 350122China School of Chemical Engineering and Pharmacy Wuhan Institute of TechnologyWuhan 430205China School of Chemistry and Chemical Engineering Beijing Institute of TechnologyBeijing 100081China Center for AIE Research Shenzhen Key Laboratory of Polymer Science and TechnologyGuangdong Research Center for Interfacial Engineering of Functional MaterialsCollege of Materials Science and EngineeringShenzhen UniversityShenzhen 518060China

Programmed death 1(PD-1)and its ligand PD-L1 are two typical immune ***-based immune checkpoint blockade(ICB)strategy targeting PD-1/PD-L1 achieved a significant therapeutic effect on ***,due to the impenetrability of antibody drugs and the occurrence of immune-related adverse events,only a minority of patients benefit from this *** multimerization has been widely proved to be an effective method to improve receptor binding affinity through a multivalent synergistic *** this study,we report a novel peptide-aggregation-induced emission(AIE)hybrid supramolecular TAP,which can self-assemble into nanofibers through non-covalent interactions such as hydrogen bonds,with a specific nanomolar affinity to PD-L1 in vivo and in *** with near-infrared agents,it can be used for tumor imaging and photothermal therapy,which enables photothermal ablation of cancer cells for generating tumor-associated antigen(TAA)and triggering a series of immunological ***,our work suggests that synthetic self-assembled peptide nanofibers can be developed as attractive platforms for active photothermal immunotherapies against cancer.

关键词： programmed death 1(PD-1) targeting peptide self-assembly immune checkpoint blockade photothermal therapy

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

王济华运用角药治疗类风湿关节炎经验

河南中医 2024年第3期44卷 351-355页

作者：王荷珺王子华杜明瑞河南省中医药大学第一附属医院河南郑州450001

王济华教授认为,类风湿关节炎早期多因外感风、寒、湿三邪,三者之间相互促进、互相转化,风寒表邪入里日久或郁而化热;病程日久多虚实夹杂,肝肾亏虚、气血不足,同时兼有寒湿痹阻、痰瘀互结。故王教授治疗痹证早期以祛邪散寒为主,兼顾清... 详细信息

王济华教授认为,类风湿关节炎早期多因外感风、寒、湿三邪,三者之间相互促进、互相转化,风寒表邪入里日久或郁而化热;病程日久多虚实夹杂,肝肾亏虚、气血不足,同时兼有寒湿痹阻、痰瘀互结。故王教授治疗痹证早期以祛邪散寒为主,兼顾清热利湿、化痰散结,中晚期则偏于滋养气血、补益肝肾。王济华教授运用角药治疗痹证颇有心得,组方精妙、配伍严谨,常用角药川芎-延胡索-白芍行气活血、柔筋止痛;忍冬藤-络石藤-青风藤清热通络、祛风除湿;半夏-陈皮-竹茹燥湿化痰、理气和中;白术-薏苡仁-茯苓益气健脾、利湿消肿;桑寄生-续断-杜仲滋补肝肾、强筋壮骨;酸枣仁-合欢皮-首乌藤宁心安神、解郁除烦。王教授临证时,追求阴阳调和平衡、气机升降有度,临床用药有药简力专、增效减负之功。

关键词：类风湿关节炎角药川芎-延胡索-白芍忍冬藤-络石藤-青风藤半夏-陈皮-竹茹白术-薏苡仁-茯苓桑寄生-续断-杜仲酸枣仁-合欢皮-首乌藤王济华

Person video alignment with human pose registration

在线全文

学校读者我要写书评

暂无评论

Frontiers of Computer Science 2023年第4期17卷 229-231页

作者： Yu ZHANG zihua wang Jingyang ZHOU Siya MI School of Computer Science and Engineering and the Key Lab of Computer Network and Information Integration(Ministry of Education)Southeast UniversityNanjing 211189China School of Cyber Science and Engineering Southeast UniversityNanjing 211189China Purple Mountain Laboratories Nanjing 211111China

1 Introduction and main *** alignment,especially human action alignment,is a challenging *** purpose is to develop an algorithm to match the same process so that videos can be *** the progress that has been made in image recognition,it is still a difficult problem for distinguishing from similar frames for alignment without context information.

关键词： alignment video frames

吐哈盆地丘东洼陷碱泉子沟断裂描述及致密油气控藏分析

在线全文

学校读者我要写书评

暂无评论

断块油气田 2024年第5期31卷 786-794页

作者：阴学彬石楠林煜杨斌郭翔孙博王兵牟克勋王梓骅中国石油东方物探公司研究院乌鲁木齐分院新疆乌鲁木齐830000 中国石油吐哈油田分公司勘探事业部新疆哈密839009 三亚学院外国语学院海南三亚572000

走滑断裂在油气成藏中具有重要的控制作用,其识别、判断和对油气藏控制要素的研究分析是当前勘探的热点。文中首次在吐哈盆地台北凹陷丘东洼陷中部发现碱泉子沟断裂,为了落实其空间展布特征、成因机制及其对油气藏的控制作用,开展了进... 详细信息

走滑断裂在油气成藏中具有重要的控制作用,其识别、判断和对油气藏控制要素的研究分析是当前勘探的热点。文中首次在吐哈盆地台北凹陷丘东洼陷中部发现碱泉子沟断裂,为了落实其空间展布特征、成因机制及其对油气藏的控制作用,开展了进一步研究。结果表明:碱泉子沟断裂在露头上水平错动、在剖面上断面陡直且发育“花状构造”、在平面上呈“雁列式”展布,并具有“四层构造”特征,走滑特征明显;碱泉子沟断裂是照壁山大断裂的派生次级走滑断裂,沿Sylveser简单剪切模式中的R′剪切面发育,结合流体包裹体均一温度推测其形成于晚印支期,早—中燕山期活动强烈,晚燕山期活动减弱;碱泉子沟断裂具有控圈、控储、控运和控藏作用,其空间结构、活动期次和与成藏期次的匹配关系决定油气运聚的流体相态、油气排替顺序和聚集位置,尤其是断裂中下层结构在中燕山期活动,后续静止封闭,这是导致下侏罗统致密油气藏大面积分布的重要原因。研究成果对吐哈盆地致密油气勘探具有非常重要的指导意义。

关键词：走滑断裂形成机制控藏作用丘东洼陷吐哈盆地

Enzymatic Conversion of Biobased Levulinic Acid into an Alternative Biofuel Candidate--Methyl Levulinate

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China Petroleum Processing & Petrochemical Technology 2020年第1期22卷 8-16页

作者： Xu Yanli Li Pan Chang Chun Xu Guizhuan Du Zeji wang zihua School of Chemical Engineering Zhengzhou UniversityZhengzhou 450001 Henan Center for Outstanding Overseas Scientists Zhengzhou 450001 College of Mechanical and Electrical Engineering Henan Agricultural UniversityZhengzhou 450002

Methyl levulinate(ML)is a promising green candidate for bio-based diesel fuel and fuel *** efficient enzyme-catalyzed process to synthesize ML from levulinic acid(LA)in methanol was *** catalytic activity of a series of lipases including Novozyme 435(N435),NRTL IM,and 40086 was screened,and the N435 was identified as the optimal biocatalyst for the *** effects of lipase amount,methyl tert-butyl ether(MTBE)volume,methanol to LA molar ratio,reaction temperature,and magnetic stirrer speed on LA conversion and ML yield were *** response surface methodology was adopted to optimize the enzymatic conversion process,and the model validation experiments showed that the predicted values corresponded well with the experimental values.A LA conversion of 90.1%and a ML yield of 89.8%were achieved under reaction conditions covering:a temperature of 45°C,a reaction time of 4.6 h,a N435 dosage of 26 mg,a methanol to LA molar ratio of 3.6:1,a MTBE volume of 3.85 mL,and a stirrer speed of 150 r/*** N435 recycling experiment indicated that the lipase activity was quite high after 12 ***,upon using crude LA prepared from carbohydrates as the reactant,the conversion of LA and the ML yield decreased due to impurities existing in the crude LA.

关键词： enzyme methyl levulinate levulinic acid biomass

Mechanism of E' center induced by γ ray radiation in silica optical fiber material

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2013年第4期24卷 28-31页

作者： LUO Wenyun XIAO Zhongyin WEN Jianxiang YIN Jianchong WU Wenkai CHEN Zhenyi wang zihua wang Tingyun School of Communication and Information Engineering Key Laboratory of Specialty Fiber Optics and Optical Access NetworksShanghai University School of Environmental and Chemical Engineering Shanghai Applied Radiation Institute Shanghai University

The characteristics of the best known defect centers E' in silica optical fiber material irradiated with ray were investigated by ESR at room temperature.A mechanism model of production of the E' center defect was *** production of E' center includes two processes creation and *** strained bonds(or oxygen replacement) in silica networks lead to the creation of new defects whose concentration increases linearly with the *** pre-existing defects produce the activation,which tends to *** to this model,the relation of E' center concentration changing with irradiation dose was obtained *** results are in good agreement with the experimental results.

关键词：光纤材料射线辐射机制石英缺陷中心二氧化硅机理模型缺陷产生